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Aliases for MEF2BNB Gene

Aliases for MEF2BNB Gene

  • MEF2B Neighbor 2 3
  • MEF2B Neighbor Gene Protein 4

External Ids for MEF2BNB Gene

Previous GeneCards Identifiers for MEF2BNB Gene

  • GC19M019288

Summaries for MEF2BNB Gene

GeneCards Summary for MEF2BNB Gene

MEF2BNB (MEF2B Neighbor) is a Protein Coding gene. Among its related pathways are L1CAM interactions and AMPK signaling.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MEF2BNB Gene

Genomics for MEF2BNB Gene

Genomic Location for MEF2BNB Gene

Start:
19,176,903 bp from pter
End:
19,192,591 bp from pter
Size:
15,689 bases
Orientation:
Minus strand

Genomic View for MEF2BNB Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MEF2BNB Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MEF2BNB Gene

No data available for Regulatory Elements for MEF2BNB Gene

Proteins for MEF2BNB Gene

  • Protein details for MEF2BNB Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96FH0-MF2NB_HUMAN
    Recommended name:
    Protein MEF2BNB
    Protein Accession:
    Q96FH0
    Secondary Accessions:
    • B2RXF9
    • Q9BT01

    Protein attributes for MEF2BNB Gene

    Size:
    119 amino acids
    Molecular mass:
    13403 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MEF2BNB Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MEF2BNB Gene

Proteomics data for MEF2BNB Gene at MOPED

Post-translational modifications for MEF2BNB Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MEF2BNB Gene

No data available for DME Specific Peptides for MEF2BNB Gene

Domains for MEF2BNB Gene

Protein Domains for MEF2BNB Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MEF2BNB Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96FH0

UniProtKB/Swiss-Prot:

MF2NB_HUMAN :
  • Q96FH0
Family:
  • Belongs to the MEF2BNB family.
genes like me logo Genes that share domains with MEF2BNB: view

No data available for Gene Families for MEF2BNB Gene

Function for MEF2BNB Gene

Gene Ontology (GO) - Molecular Function for MEF2BNB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with MEF2BNB: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MEF2BNB Gene

Localization for MEF2BNB Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MEF2BNB Gene

Pathways for MEF2BNB Gene

genes like me logo Genes that share pathways with MEF2BNB: view

Pathways by source for MEF2BNB Gene

1 BioSystems pathway for MEF2BNB Gene
3 Reactome pathways for MEF2BNB Gene

Interacting Proteins for MEF2BNB Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000425864%0d%0a9606.ENSP00000340995%0d%0a
Selected Interacting proteins: ENSP00000425864 Q96FH0-MF2NB_HUMAN for MEF2BNB Gene via STRING UniProtKB I2D

Gene Ontology (GO) - Biological Process for MEF2BNB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007507 heart development IEP 10458488
genes like me logo Genes that share ontologies with MEF2BNB: view

Transcripts for MEF2BNB Gene

mRNA/cDNA for MEF2BNB Gene

(2) REFSEQ mRNAs :
(11) Additional mRNA sequences :
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MEF2BNB Gene

MEF2B neighbor:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MEF2BNB

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for MEF2BNB
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MEF2BNB Gene

No ASD Table

Relevant External Links for MEF2BNB Gene

GeneLoc Exon Structure for
MEF2BNB
ECgene alternative splicing isoforms for
MEF2BNB

Expression for MEF2BNB Gene

mRNA expression in normal human tissues for MEF2BNB Gene

mRNA differential expression in normal tissues according to GTEx for MEF2BNB Gene

This gene is overexpressed in Whole Blood (6.7).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for MEF2BNB Gene

SOURCE GeneReport for Unigene cluster for MEF2BNB Gene Hs.153629

genes like me logo Genes that share expressions with MEF2BNB: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for MEF2BNB Gene

Orthologs for MEF2BNB Gene

This gene was present in the common ancestor of animals.

Orthologs for MEF2BNB Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MEF2BNB 35
  • 99.69 (n)
  • 100 (a)
MEF2BNB 36
  • 75 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 76 (a)
OneToMany
MEF2BNB 35
  • 90.76 (n)
  • 98.32 (a)
MEF2BNB 36
  • 98 (a)
OneToMany
dog
(Canis familiaris)
Mammalia MEF2BNB 35
  • 89.92 (n)
  • 98.32 (a)
MEF2BNB 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2310045N01Rik 35
  • 87.65 (n)
  • 98.15 (a)
2310045N01Rik 16
oppossum
(Monodelphis domestica)
Mammalia MEF2BNB 36
  • 86 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mef2bnb 35
  • 86.42 (n)
  • 97.22 (a)
chicken
(Gallus gallus)
Aves MEF2BNB 35
  • 81.13 (n)
  • 83.02 (a)
MEF2BNB 36
  • 75 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia mef2bnb 35
  • 71.52 (n)
  • 80.58 (a)
zebrafish
(Danio rerio)
Actinopterygii mef2bnb 35
  • 66.98 (n)
  • 75.47 (a)
mef2bnb 36
  • 66 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP008600 35
  • 53.47 (n)
  • 38.61 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG32590 35
  • 49.14 (n)
  • 28.87 (a)
CG32590 36
  • 16 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea K11B4.2 36
  • 21 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 27 (a)
OneToOne
Species with no ortholog for MEF2BNB:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MEF2BNB Gene

ENSEMBL:
Gene Tree for MEF2BNB (if available)
TreeFam:
Gene Tree for MEF2BNB (if available)

Paralogs for MEF2BNB Gene

Selected SIMAP similar genes for MEF2BNB Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for MEF2BNB Gene

genes like me logo Genes that share paralogs with MEF2BNB: view

No data available for Paralogs for MEF2BNB Gene

Variants for MEF2BNB Gene

Structural Variations from Database of Genomic Variants (DGV) for MEF2BNB Gene

Variant ID Type Subtype PubMed ID
nsv833779 CNV Loss 17160897
nsv911303 CNV Loss 21882294

Relevant External Links for MEF2BNB Gene

HapMap Linkage Disequilibrium report
MEF2BNB

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MEF2BNB Gene

Disorders for MEF2BNB Gene

No disorders were found for MEF2BNB Gene.

No data available for UniProtKB/Swiss-Prot for MEF2BNB Gene

Publications for MEF2BNB Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 3
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3

Products for MEF2BNB Gene

Sources for MEF2BNB Gene

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