Aliases for MEF2B Gene
External Ids for MEF2B Gene
Previous GeneCards Identifiers for MEF2B Gene
The product of this gene is a member of the MADS/MEF2 family of DNA binding proteins. The protein is thought to regulate gene expression, including expression of the smooth muscle myosin heavy chain gene. This region undergoes considerable alternative splicing, with transcripts supporting two non-overlapping loci (GeneID 729991 and 100271849) as well as numerous read-through transcripts that span both loci (annotated as GeneID 4207). Several isoforms of this protein are expressed from either this locus or from some of the read-through transcripts annotated on GeneID 4207. [provided by RefSeq, Jan 2014]
GeneCards Summary for MEF2B Gene
MEF2B (Myocyte Enhancer Factor 2B) is a Protein Coding gene. Among its related pathways are Ca-dependent events and Development Angiotensin activation of ERK. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and histone deacetylase binding. An important paralog of this gene is MEF2BNB-MEF2B.
UniProtKB/Swiss-Prot for MEF2B Gene
Transcriptional activator which binds specifically to the MEF2 element, 5-YTA[AT](4)TAR-3, found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription