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Aliases for MEDAG Gene

Aliases for MEDAG Gene

  • Mesenteric Estrogen Dependent Adipogenesis 2 3
  • Activated In W/Wv Mouse Stomach 3 Homolog 2 3 4
  • Mesenteric Estrogen-Dependent Adipose 4 2 3 4
  • Mesenteric Estrogen-Dependent Adipogenesis 2 5
  • C13orf33 3 4
  • MEDA-4 3 4
  • HAWMS3 3 4
  • AWMS3 3 4
  • MEDA4 3 4
  • Chromosome 13 Open Reading Frame 33 2

External Ids for MEDAG Gene

Previous HGNC Symbols for MEDAG Gene

  • C13orf33

Previous GeneCards Identifiers for MEDAG Gene

  • GC13P031481

Summaries for MEDAG Gene

GeneCards Summary for MEDAG Gene

MEDAG (Mesenteric Estrogen Dependent Adipogenesis) is a Protein Coding gene.

UniProtKB/Swiss-Prot for MEDAG Gene

  • Involved in processes that promote adipocyte differentiation, lipid accumulation, and glucose uptake in mature adipocytes.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MEDAG Gene

Genomics for MEDAG Gene

Regulatory Elements for MEDAG Gene

Promoters for MEDAG Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MEDAG on UCSC Golden Path with GeneCards custom track

Genomic Location for MEDAG Gene

30,906,175 bp from pter
30,925,572 bp from pter
19,398 bases
Plus strand

Genomic View for MEDAG Gene

Genes around MEDAG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MEDAG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MEDAG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MEDAG Gene

Proteins for MEDAG Gene

  • Protein details for MEDAG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Mesenteric estrogen-dependent adipogenesis protein
    Protein Accession:
    Secondary Accessions:
    • Q8IXF1
    • Q96K26
    • Q96NC8

    Protein attributes for MEDAG Gene

    303 amino acids
    Molecular mass:
    34190 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MEDAG Gene


neXtProt entry for MEDAG Gene

Proteomics data for MEDAG Gene at MOPED

Post-translational modifications for MEDAG Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MEDAG Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MEDAG Gene

Domains & Families for MEDAG Gene

Protein Domains for MEDAG Gene


Suggested Antigen Peptide Sequences for MEDAG Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MEDAG: view

No data available for Gene Families and UniProtKB/Swiss-Prot for MEDAG Gene

Function for MEDAG Gene

Molecular function for MEDAG Gene

UniProtKB/Swiss-Prot Function:
Involved in processes that promote adipocyte differentiation, lipid accumulation, and glucose uptake in mature adipocytes.

Phenotypes for MEDAG Gene

genes like me logo Genes that share phenotypes with MEDAG: view

Animal Model Products

CRISPR Products

miRNA for MEDAG Gene

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MEDAG Gene

Localization for MEDAG Gene

Subcellular locations from UniProtKB/Swiss-Prot for MEDAG Gene


Subcellular locations from

Jensen Localization Image for MEDAG Gene COMPARTMENTS Subcellular localization image for MEDAG gene
Compartment Confidence
nucleus 3
cytosol 2
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for MEDAG Gene

Pathways & Interactions for MEDAG Gene

SuperPathways for MEDAG Gene

No Data Available

Interacting Proteins for MEDAG Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: Q5VYS4-MEDAG_HUMAN ENSP00000369849 for MEDAG Gene via I2D STRING

Gene Ontology (GO) - Biological Process for MEDAG Gene


No data available for Pathways by source and SIGNOR curated interactions for MEDAG Gene

Drugs & Compounds for MEDAG Gene

No Compound Related Data Available

Transcripts for MEDAG Gene

mRNA/cDNA for MEDAG Gene

Unigene Clusters for MEDAG Gene

Mesenteric estrogen-dependent adipogenesis:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MEDAG Gene

No ASD Table

Relevant External Links for MEDAG Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MEDAG Gene

mRNA expression in normal human tissues for MEDAG Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MEDAG Gene

This gene is overexpressed in Adipose - Visceral (Omentum) (x7.3), Artery - Aorta (x6.6), Artery - Tibial (x5.3), and Artery - Coronary (x4.3).

SOURCE GeneReport for Unigene cluster for MEDAG Gene Hs.147880

mRNA Expression by UniProt/SwissProt for MEDAG Gene

Tissue specificity: Highly expressed in the visceral fat depot.
genes like me logo Genes that share expression patterns with MEDAG: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for MEDAG Gene

Orthologs for MEDAG Gene

This gene was present in the common ancestor of chordates.

Orthologs for MEDAG Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MEDAG 35
  • 90.1 (n)
  • 91.09 (a)
  • 91 (a)
(Canis familiaris)
Mammalia MEDAG 35
  • 91.81 (n)
  • 94.88 (a)
  • 93 (a)
(Mus musculus)
Mammalia Medag 35
  • 86.25 (n)
  • 91.42 (a)
Medag 16
Medag 36
  • 91 (a)
(Pan troglodytes)
Mammalia MEDAG 35
  • 99.23 (n)
  • 99.34 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Medag 35
  • 86.27 (n)
  • 92.03 (a)
(Monodelphis domestica)
Mammalia MEDAG 36
  • 41 (a)
(Ornithorhynchus anatinus)
Mammalia MEDAG 36
  • 75 (a)
(Anolis carolinensis)
Reptilia MEDAG 36
  • 60 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia medag 35
  • 56.49 (n)
  • 45.38 (a)
Species with no ortholog for MEDAG:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MEDAG Gene

Gene Tree for MEDAG (if available)
Gene Tree for MEDAG (if available)

Paralogs for MEDAG Gene

No data available for Paralogs for MEDAG Gene

Variants for MEDAG Gene

Sequence variations from dbSNP and Humsavar for MEDAG Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
VAR_030261 -

Variation tolerance for MEDAG Gene

Residual Variation Intolerance Score: 51.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.35; 63.29% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MEDAG Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MEDAG Gene

Disorders for MEDAG Gene

Relevant External Links for MEDAG

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MEDAG Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MEDAG Gene

Publications for MEDAG Gene

  1. Novel genes of visceral adiposity: identification of mouse and human mesenteric estrogen-dependent adipose (MEDA)-4 gene and its adipogenic function. (PMID: 22510272) Zhang H. … Sairam M.R. (Endocrinology 2012) 2 3 4 67
  2. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for MEDAG Gene

Sources for MEDAG Gene

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