MED8 Gene
protein-coding GIFtS: 50
GCID: GC01M043849
|
|
mediator complex subunit 8(Previous names: mediator of RNA polymerase II transcription, subunit 8...)
| |
Aliases
for MED8 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Mediator Complex Subunit 81 2 3 | | MGC196411 | | ARC321 2 3 | | Mediator Of RNA Polymerase II Transcription, Subunit 8 Homolog (S. Cerevisiae)1 | | Activator-Recruited Cofactor 32 KDa Component2 3 | | Mediator Of RNA Polymerase II Transcription Subunit 82 | | MGC175441 | | Mediator Of RNA Polymerase II Transcription Subunit MED82 |
Export aliases for MED8 gene to outside databasesPrevious GC identifers: GC01U990453 GC01M042850 GC01M043279 GC01M043262 GC01M043518 GC01M043622 GC01M041968 |
Summaries
for MED8 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MED8:
This gene encodes a protein component of the mediator complex, which aids in transcriptional activation throughinteraction with RNA polymerase II and gene-specific transcription factors. The encoded protein may also function inubiquitin ligation and protein degradation. Alternatively spliced transcript variants encoding multiple isoforms havebeen observed for this gene. (provided by RefSeq, Jan 2013)
UniProtKB/Swiss-Prot: MED8_HUMAN, Q96G25Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNApolymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatoryproteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by directinteractions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complexwith RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of targetproteins
Gene Wiki entry for MED8
|
Genomic Views
for MED8 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MED8 gene promoter:
TBP ISGF-3 NF-1/L NF-1 AP-4
Other transcription factors
Search SABiosciences Chromatin IP Primers for MED8
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MED8 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p34.2 Ensembl cytogenetic band: 1p34.2 HGNC cytogenetic band: 1p34.1MED8 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M043849: view genomic region
(about GC identifiers)
Start:
|
43,849,588 bp from pter |
End:
|
43,855,483 bp from pter |
Size:
|
5,896 bases |
Orientation:
|
minus strand |
|
Proteins
for MED8 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MED8_HUMAN, Q96G25 (See
protein sequence)Recommended Name: Mediator of RNA polymerase II transcription subunit 8 Size: 268 amino acids; 29080 Da
Subunit: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11,MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26,MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinctmodule termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module insupporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinctsubunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP. May be part of a multisubunit E3ubiquitin-protein ligase complex with the elongin BC complex (TCEB1 and TCEB2), CUL2 and RBX1
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=BG722466; Type=Frameshift; Positions=258;
Secondary accessions: A9IZ91 A9IZ92 Q5JUY8 Q96FQ4Alternative splicing: 3 isoforms: Q96G25-1 Q96G25-2 Q96G25-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MED8: NX_Q96G25
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96G25
MED8 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001001653.1 NP_443109.2 NP_963836.2
ENSEMBL proteins: ENSP00000290663 ENSP00000361535 ENSP00000361533 Reactome Protein details: Q96G25
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
MED8 for ontologies About GeneDecksing
MED8 Antibody Products:
Assay Products for MED8: |
Protein
Domains /
Families
for MED8 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MED8 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96G25ProtoNet protein and cluster: Q96G25 UniProtKB/Swiss-Prot: MED8_HUMAN, Q96G25Domain: The elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x(3)-C-x(3)-[AILV]Similarity: Belongs to the Mediator complex subunit 8 family |
Function
for MED8 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MED8_HUMAN, Q96G25Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNApolymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatoryproteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by directinteractions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complexwith RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of targetproteins
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MED8 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MED8 (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): MED8 (NM_052877) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MED8 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MED8 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MED8 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001104 | RNA polymerase II transcription cofactor activity |
IEA | -- | | GO:0005515 | protein binding |
IPI | 12149480 |
MED8 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for MED8:
|
Pathways & Interactions
for MED8 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | | | 2 | Transcriptional Regulation of White Adipocyte Differentiation | | | 3 | Axon guidance | |
Pathway sources
See GeneCards unified pathways
Show all pathways
4 
Reactome Pathways for MED8
UniProtKB/Swiss-Prot: MED8_HUMAN, Q96G25Pathway: Protein modification; protein ubiquitination
MED8 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MED8
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/108 Interacting proteins for MED8 (Q96G251, 2, 3 ENSP000002906634) via UniProtKB, MINT, STRING, and/or I2D (see all 108)
| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| PEX14 | O753812, 3, ENSP000003490164 | MINT-63204 I2D:
score=5 STRING: ENSP00000349016 | | TCEB2 | Q153701, 3, ENSP000002623064 | EBI-394405,EBI-301238 I2D:
score=2 STRING: ENSP00000262306 | | HSPB3 | Q129882, 3 | MINT-64108 I2D:
score=5 | | SNTA1 | Q134242, 3 | MINT-64135 I2D:
score=4 | | TCEB1 | Q153691, 3, ENSP000002848114 | EBI-394405,EBI-301231 I2D:
score=4 STRING: ENSP00000284811 |
About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006367 | transcription initiation from RNA polymerase II promoter |
TAS | -- | | GO:0010467 | gene expression |
TAS | -- | | GO:0016567 | protein ubiquitination |
IEA | -- |
MED8 for ontologies About GeneDecksing
|
Drugs & Compounds
for MED8 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MED8
Search CenterWatch for drugs/clinical trials and news about MED8
|
Transcripts
for MED8 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MED8 gene (3 alternative transcripts): NM_001001653.2 NM_052877.4 NM_201542.4 Unigene Cluster for MED8: Mediator complex subunit 8 Hs.301756 [show with all ESTs]Unigene Representative Sequence: BM4579755 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000290663(uc001cje.1) ENST00000372457(uc001cjg.4) ENST00000372455(uc001cjf.4)
ENST00000460803 ENST00000473560
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MED8 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MED8 (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): MED8 (NM_052877) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MED8 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MED8 |
Additional cDNA sequence: AF521562.1 BC010543.1 16 DOTS entries: DT.92470414 DT.102837558 DT.100707551 DT.97848207 DT.100028374 DT.448349 DT.100886652 DT.100728317 DT.92470444 DT.91747218 DT.92470393 DT.121444985 DT.92020732 DT.95327446 DT.75104753 DT.99972132 24/728 AceView cDNA sequences (see all 728): BQ228100 CF552704 BU163168 CR596193 AA031470 AL549859 NM_001001651 BQ334434 NM_201542 CA307454 BU687589 BE328199 BU838268 AA482416 AA402217 BU161349 BU185747 BU185513 BM974606 BM823298 CB216011 BP356234 BU553636 BE544249
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for MED8 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | · | 7c | ^ | 8 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | |
| SP2: | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MED8
|
Expression
for MED8 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MED8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGCAGGGGTT
About this image
See MED8 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MED8
SOURCE GeneReport for Unigene cluster: Hs.301756
SABiosciences Custom PCR Arrays for MED8
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MED8
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MED8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MED8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MED8 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MED8 |
Orthologs
for MED8 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for MED8 gene from 7/22 species (see all 22) About this table
ENSEMBL Gene Tree for MED8 (if available)
TreeFam Gene Tree for MED8 (if available) |
Paralogs
for MED8 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MED8 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MED8 (43849588 - 43855483 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MED8: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MED8 |
|
Disorders
/ Diseases
for MED8 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MED8 for disorders About GeneDecksing
OMIM gene information: 607956
OMIM disorders: --
4  diseases for MED8: About MalaCardsintrahepatic cholangiocarcinoma cholangiocarcinoma hepatocellular carcinoma carcinoma
Export disorders for MED8 gene to outside databases
|
Publications
for MED8 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MED8 gene, integrated from 9 sources (see all 30):
(articles sorted by number of sources associating them with MED8) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase. (PubMed id 12149480)1, 2, 3 Brower C.S.... Conaway R.C. (2002)
- MED1/TRAP220 exists predominantly in a TRAP/Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription. (PubMed id 15989967)1, 2 Zhang X....Roeder R.G. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. (PubMed id 15175163)1, 2 Sato S....Conaway R.C. (2004)
- Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3. (PubMed id 12584197)1, 2 Sato S....Conaway J.W. (2003)
- Composite co-activator ARC mediates chromatin-directed transcriptional activation. (PubMed id 10235267)1, 2 Naeaer A.M....Tjian R. (1999)
- Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways. (PubMed id 9671713)1, 3 Jiang Y.W.... Kornberg R.D. (1998)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Screening and identification of host factors interact ing with UL14 of herpes simplex virus 1. (PubMed id 21512757)1 Wu F....Zheng C. (2011)
|
External Searches for MED8 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MED8 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MED8 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MED8 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MED8 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MED8 gene:
Search GeneIP for patents involving MED8
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MED8 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MED8 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MED8 | | | OriGene Protein Over-expression Lysate for MED8 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MED8 | | OriGene 3'-UTR Clone for MED8 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MED8 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MED8 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MED8 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MED8 | | OriGene Custom Protein Services for MED8 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MED8 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MED8 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MED8 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MED8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MED8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MED8 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for MED8 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | MED8 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MED8 |
|  |  |  | | | | Search ThermoFisher Antibodies for MED8 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MED8 |
|
|
|
|
