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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MED30 Gene

protein-coding   GIFtS: 49
GCID: GC08P118603

mediator complex subunit 30

(Previous name: thyroid hormone receptor associated protein 6 )
(Previous symbol: THRAP6)
 Explore 3 diseases affiliated with
MED30 via our new
 Human Malady Compendium 
Biological research products
for MED30
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Mediator Complex Subunit 301 2 3     TRAP/Mediator Complex Component TRAP252 3
THRAP61 2 3 5     MED30S2
TRAP251 2 3 5     Mediator Of RNA Polymerase II Transcription Subunit 302
Thyroid Hormone Receptor Associated Protein 61 2     Putative Mediator Of RNA Polymerase II Transcription Subunit 302
Thyroid Hormone Receptor-Associated Protein 62 3     Trap253
Thyroid Hormone Receptor-Associated Protein Complex 25 KDa Component2 3     

External Ids:    HGNC: 230321   Entrez Gene: 903902   Ensembl: ENSG000001647587   OMIM: 6102375   UniProtKB: Q96HR33   

Export aliases for MED30 gene to outside databases

Previous GC identifer: GC08P113859


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MED30:
The multiprotein TRAP/Mediator complex facilitates gene expression through a wide variety of transcriptional
activators. MED30 is a component of this complex that appears to be metazoan specific (Baek et al., 2002 (PubMed
11909976)).(supplied by OMIM, Nov 2010)

UniProtKB/Swiss-Prot: MED30_HUMAN, Q96HR3
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA
polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory
proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex
with RNA polymerase II and the general transcription factors

Gene Wiki entry for MED30


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.1  NT_008046.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MED30 gene promoter:
         HFH-3   TBP   AML1a   Olf-1   CUTL1   AREB6   POU2F1   POU2F1a   FOXJ2 (long isoform)   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMED30 promoter sequence
   Search SABiosciences Chromatin IP Primers for MED30

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MED30


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.11   Ensembl cytogenetic band:  8q24.11   HGNC cytogenetic band: 8q24.11

MED30 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MED30 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P118603:  view genomic region     (about GC identifiers)

Start:
118,532,952 bp from pter      End:
118,552,501 bp from pter
Size:
19,550 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MED30_HUMAN, Q96HR3 (See protein sequence)
Recommended Name: Mediator of RNA polymerase II transcription subunit 30  
Size: 178 amino acids; 20277 Da
Subunit: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11,
MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26,
MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct
module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in
supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct
subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP
Subcellular location: Nucleus (Probable)

Explore the universe of human proteins at neXtProt for MED30: NX_Q96HR3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96HR3

  • MED30 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_542382.1  
    ENSEMBL proteins: 
     ENSP00000297347   ENSP00000431051  
    Reactome Protein details: Q96HR3
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: MED30
    OriGene Protein Over-expression Lysate: MED30
    OriGene Custom Protein Services for MED30 
    GenScript Custom Purified and Recombinant Proteins Services for MED30
    Novus Biologicals MED30 Protein
    Novus Biologicals MED30 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for MED30

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA10235267
    GO:0005654nucleoplasm TAS--
    GO:0016592mediator complex IDA10198638


    MED30 for ontologies           About GeneDecksing



    MED30 Antibody Products: 
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    Uscn Antibodies for MED30
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    Uscn ELISAs and CLIAs for MED30


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    MED30 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR021019 Mediator_Med30_met

    Graphical View of Domain Structure for InterPro Entry Q96HR3

    ProtoNet protein and cluster: Q96HR3

    UniProtKB/Swiss-Prot: MED30_HUMAN, Q96HR3
    Similarity: Belongs to the Mediator complex subunit 30 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: MED30_HUMAN, Q96HR3
    Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA
    polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory
    proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct
    interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex
    with RNA polymerase II and the general transcription factors

    miRNA
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    OriGene 3'-UTR Clone: MED30
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MED30
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate MED30
    SwitchGear 3'UTR luciferase reporter plasmidMED30 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MED30 (see all 4)
    OriGene shRNA RFP: MED30
    OriGene siRNA: MED30
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MED30

    Gene Editing
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MED30 (see all 3)
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: MED30 (NM_080651)
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MED30
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MED30 

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    Search LifeMap BioReagents cell lines for MED30

    In Situ Assay
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    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for MED30

    Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001104RNA polymerase II transcription cofactor activity IDA10198638
    GO:0003712transcription cofactor activity IDA12218053
    GO:0004872receptor activity IDA12218053
    GO:0005515protein binding IPI--
    GO:0030374ligand-dependent nuclear receptor transcription coactivator activity NAS10235266


    MED30 for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for MED30:
     Decreased viability  Increased circadian period len  Synthetic lethal with c-Myc af 

    Animal Models:
         6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Med30):
     cardiovascular system  cellular  growth/size  hematopoietic system  mortality/aging 
     muscle 

    MED30 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Generic Transcription Pathway
    Generic Transcription Pathway1.00
    Gene Expression0.46
    2HIV Infection
    Transcription Ligand-Dependent Transcription of Retinoid-Target genes0.28
    Transcription_Ligand-Dependent Transcription of Retinoid-Target genes0.28
    3Transcriptional Regulation of White Adipocyte Differentiation
    Transcriptional Regulation of White Adipocyte Differentiation1.00
    4Axon guidance
    Developmental Biology0.69

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for MED30
        Transcription Ligand-Dependent Transcription of Retinoid-Target genes


    1 GeneGo (Thomson Reuters) Pathway for MED30
        Transcription Ligand-Dependent Transcription of Retinoid-Target genes

    4        Reactome Pathways for MED30
        Developmental Biology
    Transcriptional Regulation of White Adipocyte Differentiation
    Generic Transcription Pathway
    Gene Expression



    MED30 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MED30

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/85 Interacting proteins for MED30 (Q96HR33 ENSP000002973474) via UniProtKB, MINT, STRING, and/or I2D (see all 85)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MED28Q9H2043, ENSP000002373804I2D: score=5 STRING: ENSP00000237380
    MED10Q9BTT43, ENSP000002557644I2D: score=2 STRING: ENSP00000255764
    MED19A0JLT23, ENSP000003373404STRING: ENSP00000337340 I2D: score=2 
    MED20Q9H9443, ENSP000002653504I2D: score=2 STRING: ENSP00000265350
    MED8Q96G253, ENSP000002906634I2D: score=2 STRING: ENSP00000290663
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006367transcription initiation from RNA polymerase II promoter TAS--
    GO:0010467gene expression TAS--
    GO:0019827stem cell maintenance IEA--
    GO:0030518intracellular steroid hormone receptor signaling pathway IDA11867769
    GO:0030521androgen receptor signaling pathway IDA12218053


    MED30 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MED30
    Search CenterWatch for drugs/clinical trials and news about MED30 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MED30 gene: 
    NM_080651.2  

    Unigene Cluster for MED30:

    Mediator complex subunit 30
    Hs.492612  [show with all ESTs]
    Unigene Representative Sequence: BM458612
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000297347(uc003yoj.3 uc011lib.2) ENST00000519879 ENST00000522839
    ENST00000519391

    miRNA
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    OriGene 3'-UTR Clone: MED30
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MED30
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    SwitchGear 3'UTR luciferase reporter plasmidMED30 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MED30 (see all 4)
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    Clone
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    GenScript: all cDNA clones in your preferred vector: MED30 (NM_080651)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MED30
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MED30 
    Primer
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    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MED30
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MED30
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MED30
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MED30

    Additional cDNA sequence: 

    AY083305.1 BC008226.1 FM179284.1 

    4 DOTS entries:

    DT.220335  DT.86844569  DT.91697509  DT.91697498 

    24/67 AceView cDNA sequences (see all 67):

    AW103865 CR602778 CN483837 AW162597 BX281284 AY083305 BM458612 AA573111 
    AW614040 AW439215 AI184166 CB305552 BE618444 AI767024 CF529815 AI656945 
    AA810068 NM_080651 BI757886 BC008226 BM505094 AI149753 BI769041 AW026676 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MED30 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AATTGAATAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See MED30 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MED30

    SOURCE GeneReport for Unigene cluster: Hs.492612

    UniProtKB/Swiss-Prot: MED30_HUMAN, Q96HR3
    Tissue specificity: Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle

        SABiosciences Custom PCR Arrays for MED30
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MED30
    In Situ
    Assay Products:
     

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for MED30

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for MED30 gene from 6/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Med301 , 5 mediator complex subunit 301, 5 90.07(n)1
    94.94(a)1
      15 (19.95 cM)5
    697901  NM_027212.21  NP_081488.11 
     527124455 
    chicken
    (Gallus gallus)
    Aves MED301 mediator complex subunit 30 80.79(n)
    88.7(a)
      420284  XM_418397.2  XP_418397.1 
    lizard
    (Anolis carolinensis)
    Reptilia MED306
    --
    88(a)
    1 ↔ 1
    4(6869375-6886373)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.290362 Xenopus laevis transcribed sequence with moderate similarity more 74.56(n)    48036292 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc731132 hypothetical protein MGC73113 76.78(n)   393690  BC059478.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta MED301 Mediator complex subunit 30 55.56(n)
    41.67(a)
      38078  NM_138202.3  NP_612046.1 


    ENSEMBL Gene Tree for MED30 (if available)
    TreeFam Gene Tree for MED30 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/354 NCBI SNPs in MED30 are shown (see all 354    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1140135651,2
    F,--118531395(+) GTCCTC/AACACT 1 -- us2k11Minor allele frequency- A:0.12WA 118
    rs1442925921,2
    --118531404(+) CTGAAC/TTTCTT 1 -- us2k10--------
    rs1911522881,2
    --118531448(+) CTTCAC/GGTGTT 1 -- us2k10--------
    rs625211981,2
    --118531470(+) TCCTCG/ATCCTC 1 -- us2k14Minor allele frequency- A:0.14NA WA EA 360
    rs1830526281,2
    --118531585(+) TATCAG/TGAACT 1 -- us2k10--------
    rs1876118281,2
    --118531587(+) TCAGGA/GACTTT 1 -- us2k10--------
    rs726721261,2
    C,F,--118531669(+) GTTTGT/GTCAGT 1 -- us2k13Minor allele frequency- G:0.06WA NA EA 358
    rs772356921,2
    --118531676(+) CAGTAC/GGCTAT 1 -- us2k10--------
    rs1912786791,2
    --118531708(+) CATAAC/TAGGTG 1 -- us2k10--------
    rs2003266641,2
    --118531917(+) TGAAC-/AGTAAG
            
    AGTAA
    1 -- us2k10--------

    HapMap Linkage Disequilibrium report for MED30 (118532952 - 118552501 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for MED30: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MED30
    DNA2.0 Custom Variant and Variant Library Synthesis for MED30

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    MED30 for disorders           About GeneDecksing

    OMIM gene information: 610237    OMIM disorders: --

    3 diseases for MED30:    About MalaCards
    thyroiditis    conjunctivitis    neuronitis


    Export disorders for MED30 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MED30 gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with MED30)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. MED1/TRAP220 exists predominantly in a TRAP/Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription. (PubMed id 15989967)1, 2 Zhang X....Roeder R.G. (2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. (PubMed id 15175163)1, 2 Sato S....Conaway R.C. (2004)
    4. Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3. (PubMed id 12584197)1, 2 Sato S....Conaway J.W. (2003)
    5. Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s. (PubMed id 11909976)1, 2 Baek H.J.... Roeder R.G. (2002)
    6. Two new susceptibility loci for Kawasaki disease ident ified through genome-wide association analysis. (PubMed id 22446961)1 Lee Y.C....Wu J.Y. (2012)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    9. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 90390 HGNC: 23032 AceView: THRAP6 Ensembl:ENSG00000164758 euGenes: HUgn90390
    ECgene: MED30 H-InvDB: MED30

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MED30 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MED30 gene:
    Search GeneIP for patents involving MED30

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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