Aliases for MED30 Gene
External Ids for MED30 Gene
Previous HGNC Symbols for MED30 Gene
Previous GeneCards Identifiers for MED30 Gene
The multiprotein TRAP/Mediator complex facilitates gene expression through a wide variety of transcriptional activators. MED30 is a component of this complex that appears to be metazoan specific (Baek et al., 2002 [PubMed 11909976]).[supplied by OMIM, Nov 2010]
GeneCards Summary for MED30 Gene
MED30 (Mediator Complex Subunit 30) is a Protein Coding gene. Among its related pathways are Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) and Thyroid hormone signaling pathway. GO annotations related to this gene include receptor activity and ligand-dependent nuclear receptor transcription coactivator activity.
UniProtKB/Swiss-Prot for MED30 Gene
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.