MED21 Gene
protein-coding GIFtS: 51
GCID: GC12P027175
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|
mediator complex subunit 21(Previous names: SRB7 (suppressor of RNA polymerase B, yeast) homolog, SRB7...)
(Previous symbol: SURB7)
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Aliases
for MED21 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Mediator Complex Subunit 211 2 3 | | RNAPII Complex Component SRB72 3 | | SRB71 2 3 5 | | SRB7 (Suppressor Of RNA Polymerase B, Yeast) Homolog1 | | SURB71 2 3 5 | | SRB7 Suppressor Of RNA Polymerase B Homolog (Yeast)1 | | HSrb71 | | Mediator Of RNA Polymerase II Transcription Subunit 212 | | RNA Polymerase II Holoenzyme Component SRB72 3 | | SRB7 Suppressor Of RNA Polymerase B Homolog2 |
Export aliases for MED21 gene to outside databasesPrevious GC identifers: GC12P027067 GC12P026945 |
Summaries
for MED21 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MED21:
This gene encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNApolymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. Apseudogene of this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants.(provided by RefSeq, Nov 2012)
UniProtKB/Swiss-Prot: MED21_HUMAN, Q13503Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNApolymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatoryproteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by directinteractions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complexwith RNA polymerase II and the general transcription factors
Gene Wiki entry for MED21
|
Genomic Views
for MED21 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_009714.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MED21 gene promoter:
AhR AML1a POU2F1 POU2F1a Nkx2-5 Arnt C/EBPalpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for MED21
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MED21 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12p11.23 Ensembl cytogenetic band: 12p11.23 HGNC cytogenetic band: 12p12MED21 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P027175: view genomic region
(about GC identifiers)
Start:
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27,175,479 bp from pter |
End:
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27,219,276 bp from pter |
Size:
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43,798 bases |
Orientation:
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plus strand |
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Proteins
for MED21 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MED21_HUMAN, Q13503 (See
protein sequence)Recommended Name: Mediator of RNA polymerase II transcription subunit 21 Size: 144 amino acids; 15564 Da
Subunit: Interacts with PPARG (By similarity). Component of the Mediator complex, which is composed of MED1, MED4,MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21,MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC andCDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active thanMediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complexlacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP. Interacts withTHRA in a ligand-dependent fashion
Subcellular location: Nucleus (Probable)
Secondary accessions: B2R4I3 Q6IB05 Q92811Explore the universe of human proteins at neXtProt for MED21: NX_Q13503
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13503
MED21 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001258740.1 NP_004255.2
ENSEMBL proteins: ENSP00000442126 ENSP00000282892 ENSP00000444297 Reactome Protein details: Q13503
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table
MED21 for ontologies About GeneDecksing
MED21 Antibody Products:
Assay Products for MED21: |
Protein
Domains /
Families
for MED21 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MED21 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q13503ProtoNet protein and cluster: Q13503 UniProtKB/Swiss-Prot: MED21_HUMAN, Q13503Similarity: Belongs to the Mediator complex subunit 21 family |
Function
for MED21 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MED21_HUMAN, Q13503Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNApolymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatoryproteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by directinteractions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complexwith RNA polymerase II and the general transcription factors
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MED21 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MED21
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MED21 (NM_004264) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MED21 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MED21 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MED21 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
MED21 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for MED21:
Animal Models:
Mouse knock-out Med21tm1Ryng for MED21
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Med21):
MED21 for phenotypes About GeneDecksing
|
Pathways & Interactions
for MED21 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | HIV Infection | | | 2 | Transcriptional Regulation of White Adipocyte Differentiation | | | 3 | Axon guidance | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for MED21
1  GeneGo (Thomson Reuters) Pathway for MED21
2 
Reactome Pathways for MED21
MED21 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MED21
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/107 Interacting proteins for MED21 (Q135033 ENSP000002828924) via UniProtKB, MINT, STRING, and/or I2D (see all 107)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001824 | blastocyst development |
IEA | -- | | GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006357 | regulation of transcription from RNA polymerase II promoter |
TAS | 8598913 | | GO:0019827 | stem cell maintenance |
IEA | -- | | GO:0045944 | positive regulation of transcription from RNA polymerase II promoter |
IDA | 12037571 |
MED21 for ontologies About GeneDecksing
|
Drugs & Compounds
for MED21 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MED21
Search CenterWatch for drugs/clinical trials and news about MED21
|
Transcripts
for MED21 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MED21 gene (2 alternative transcripts): NM_001271811.1 NM_004264.4 Unigene Cluster for MED21: Mediator complex subunit 21 Hs.286145 [show with all ESTs]Unigene Representative Sequence: NR_0734646 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000546323 ENST00000536503 ENST00000282892(uc001rhp.1 uc009zjh.1)
ENST00000536711 ENST00000538186 ENST00000544998
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MED21 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MED21
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MED21 (NM_004264) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MED21 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MED21 |
Additional cDNA sequence: AK309064.1 AK311838.1 BC008380.1 CR456999.1 NR_073463.1 NR_073464.1 U46837.1 U52960.1 9 DOTS entries: DT.75184631 DT.95321003 DT.121142075 DT.121142068 DT.121142069 DT.121142072 DT.121142070 DT.40203905 DT.92430897 24/191 AceView cDNA sequences (see all 191): T17234 AI961119 AA877665 AW051625 CR621668 AA449476 F13227 AW341584 AA449905 AW293367 BM920061 AA450370 AA314508 CA426752 Z45389 BQ017440 BM993369 AL548435 BU661021 BQ772003 AA370665 BU169702 BQ879565 BU728538
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for MED21 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5 |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | - | | - | | | | |
| SP2: | | | | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MED21
|
Expression
for MED21 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MED21 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAATACATTA
About this image
See MED21 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MED21
SOURCE GeneReport for Unigene cluster: Hs.286145
SABiosciences Custom PCR Arrays for MED21
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MED21
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MED21 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MED21 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MED21 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MED21 |
Orthologs
for MED21 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for MED21 gene from 7/23 species (see all 23) About this table
ENSEMBL Gene Tree for MED21 (if available)
TreeFam Gene Tree for MED21 (if available) |
Paralogs
for MED21 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MED21 gene
MED21 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for MED21
PGOHUM00000260419
|
Genomic Variants
for MED21 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MED21 (27175479 - 27219276 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MED21: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MED21 |
|
Disorders
/ Diseases
for MED21 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MED21 for disorders About GeneDecksing
OMIM gene information: 603800
OMIM disorders: --
4  diseases for MED21: About MalaCardsimmunodeficiency thyroiditis pancreatic cancer pancreatitis
Export disorders for MED21 gene to outside databases
|
Publications
for MED21 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MED21 gene, integrated from 9 sources (see all 48):
(articles sorted by number of sources associating them with MED21) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A mammalian SRB protein associated with an RNA polymerase II holoenzyme. (PubMed id 8598913)1, 2, 3 Chao D.M.... Young R.A. (1996)
- NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription. (PubMed id 9734358)1, 2, 9 Sun X.... Reinberg D. (1998)
- MED1/TRAP220 exists predominantly in a TRAP/Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription. (PubMed id 15989967)1, 2 Zhang X....Roeder R.G. (2005)
- hSrb7, an essential human Mediator component, acts as a coactivator for the thyroid hormone receptor. (PubMed id 15249124)1, 2 Nevado J.... Aranda A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. (PubMed id 15175163)1, 2 Sato S....Conaway R.C. (2004)
- A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation. (PubMed id 10024883)1, 2 Gu W.... Roeder R.G. (1999)
- A human RNA polymerase II complex associated with SRB and DNA-repair proteins. (PubMed id 8609996)1, 2 Maldonado E.... Reinberg D. (1996)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Mediator acts upstream of the transcriptional activato r Gal4. (PubMed id 22479149)1 Ang K....Lehming N. (2012)
|
External Searches for MED21 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MED21 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MED21 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MED21 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MED21 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MED21 gene:
Search GeneIP for patents involving MED21
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MED21 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MED21 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MED21 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MED21 | | | OriGene Protein Over-expression Lysate for MED21 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MED21 | | OriGene 3'-UTR Clone for MED21 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MED21 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MED21 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MED21 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MED21 | | OriGene Custom Protein Services for MED21 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MED21 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MED21 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MED21 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MED21 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MED21 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MED21 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for MED21 |
| |  |  |  |  | | | | |
 |
 |
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 | | | MED21 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MED21 |
|  |  |  | | | | Search ThermoFisher Antibodies for MED21 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MED21 |
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