MED12L Gene
protein-coding GIFtS: 49
GCID: GC03P150803
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|
mediator complex subunit 12-like(Previous names: mediator of RNA polymerase II transcription, subunit 12...)
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Aliases for MED12L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Mediator Complex Subunit 12-Like1 2 | | NOPAR2 5 | | TNRC11L1 2 3 | | Mediator Of RNA Polymerase II Transcription, Subunit 12 Homolog (S.Cerevisiae)-Like1 | | TRALP1 2 3 | | Mediator Of RNA Polymerase II Transcription Subunit 12-Like Protein2 | | TRALPUSH1 2 3 | | Mediator Of RNA Polymerase II Transcription, Subunit 12 Homolog-Like2 | | KIAA16351 3 5 | | No Opposite Paired Repeat Protein2 | | Thyroid Hormone Receptor-Associated-Like Protein2 3 | | Mediator Complex Subunit 12-Like Protein3 | | Trinucleotide Repeat-Containing Gene 11 Protein-Like2 3 | | |
Export aliases for MED12L gene to outside databasesPrevious GC identifers: GC03P152287 GC03P148177 |
Summaries for MED12L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for MED12L: The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation ofnearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators withthe basal transcription machinery. (provided by RefSeq, May 2010) UniProtKB/Swiss-Prot: MD12L_HUMAN, Q86YW9Function: May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearlyall RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specificregulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters bydirect interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiationcomplex with RNA polymerase II and the general transcription factors (By similarity)
|
Genomic Views for MED12L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_005612.16
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the MED12L gene promoter: USF1 Elk-1 Pax-5 USF2 USF-1:USF-2 LCR-F1 Evi-1 CP2 Zic1 USF-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for MED12L
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MED12L |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3q25.1 Ensembl cytogenetic band: 3q25.1 HGNC cytogenetic band: 3q25.1MED12L Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P150803: view genomic region
(about GC identifiers)
Start:
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150,803,484 bp from pter |
End:
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151,154,860 bp from pter |
Size:
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351,377 bases |
Orientation:
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plus strand |
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Proteins for MED12L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: MD12L_HUMAN, Q86YW9 (See
protein sequence)Recommended Name: Mediator of RNA polymerase II transcription subunit 12-like protein Size: 2145 amino acids; 240120 Da
Subunit: May be a component of the Mediator complex, which is known to be composed of MED1, MED4, MED6, MED7, MED8,MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24,MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form adistinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking thismodule in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or moredistinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP (By similarity)
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=AAF24035.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknownorigin in the N-terminal part and potential poly-A sequence; Sequence=BAB14198.1; Type=Erroneous initiation;
Secondary accessions: Q96PC7 Q96PC8 Q9H9M5 Q9HCD7 Q9UI69Alternative splicing: 4 isoforms: Q86YW9-1 Q86YW9-2 Q86YW9-3 Q86YW9-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MED12L: NX_Q86YW9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86YW9 MED12L Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins: NP_443728.3 ENSEMBL proteins: ENSP00000403308 ENSP00000310760 ENSP00000417235 ENSP00000273432 ENSP00000417420 Human Recombinant Protein Products for MED12L:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016592 | mediator complex |
IEA | -- |
MED12L for ontologies About GeneDecksing
MED12L Antibody Products: Assay Products for MED12L: |
Protein
Domains / Families for MED12L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MED12L for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q86YW9ProtoNet protein and cluster: Q86YW9 UniProtKB/Swiss-Prot: MD12L_HUMAN, Q86YW9Similarity: Belongs to the Mediator complex subunit 12 family |
Function for MED12L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: MD12L_HUMAN, Q86YW9Function: May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearlyall RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specificregulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters bydirect interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiationcomplex with RNA polymerase II and the general transcription factors (By similarity) Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001104 | RNA polymerase II transcription cofactor activity |
IEA | -- | | GO:0008013 | beta-catenin binding |
IEA | -- |
MED12L for ontologies About GeneDecksing
Phenotypes: 3 GenomeRNAi human phenotypes for MED12L: Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MED12L (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MED12L OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MED12L (NM_053002) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MED12L | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MED12L  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MED12L |
|
Pathways & Interactions for MED12L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MED12L
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/562 Interacting proteins for MED12L (Q86YW92, 3 ENSP000004172354) via UniProtKB, MINT, STRING, and/or I2D (see all 562)About this table
|
Drugs & Compounds for MED12L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MED12L for compounds About GeneDecksing
Browse Tocris compounds for MED12L 1 PharmGKB related drug/compound annotation for MED12L gene About this tableSearch CenterWatch for drugs/clinical trials and news about MED12L / MD12L 
|
Transcripts for MED12L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for MED12L gene: NM_053002.4 Unigene Cluster for MED12L: Mediator complex subunit 12-like Hs.744234 [show with all ESTs]Unigene Representative Sequence: NM_0530029 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000469768 ENST00000422248(uc003eym.1 uc003eyo.3) ENST00000309237(uc003eyn.3) ENST00000474524(uc003eyp.3 uc011bnz.2) ENST00000273432(uc003eyy.1) ENST00000480026 ENST00000491549 ENST00000468305 ENST00000488092
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MED12L (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MED12L OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MED12L (NM_053002) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MED12L | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MED12L  |
Additional cDNA sequence: AB046855.1 AF087980.1 AF090917.1 AF388364.1 AF388365.1 AF399708.1 AK022714.1 AK124913.1 AK128165.1 7 DOTS entries: DT.40128724 DT.101978528 DT.97821934 DT.95083041 DT.120862017 DT.404239 DT.97811078 24/35 AceView cDNA sequences (see all 35): AK022714 AU125717 AF399708 BX484379 AF388365 AA292658 AF388364 BX956402 AK128165 AI018271 NM_053002 AU132578 BF970855 AU154084 AK124913 AA931311 AF090917 AB046855 BG620396 AA428945 BX108326 AA648291 H97302 AF087980 GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for MED12L About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for MED12L
|
Expression for MED12L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MED12L expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CCTATGGCTG
 About this image See MED12L Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for MED12L
SOURCE GeneReport for Unigene cluster: Hs.744234 SABiosciences Custom PCR Arrays for MED12L
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MED12L Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat MED12L | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MED12L | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MED12L | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MED12L |
Orthologs for MED12L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for MED12L gene from 4/18 species (see all 18) About this table
ENSEMBL Gene Tree for MED12L (if available) TreeFam Gene Tree for MED12L (if available)  |
Paralogs for MED12L gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for MED12L gene
- MED122
2 SIMAP similar genes for MED12L using alignment to 4 protein entries: MD12L_HUMAN (see all proteins):TNRC11 MED12
MED12L for paralogs About GeneDecksing
|
Genomic Variants for MED12L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 3 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for MED12L (150803484 - 151053484 bp, first 250kb of MED12L)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 5 variations for MED12L 4 CNVs: 4356 36082 32525 3456 1 Indel: 46308  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MED12L |
|
Disorders
/ Diseases for MED12L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MED12L for disorders About GeneDecksing
OMIM gene information: 611318
OMIM disorders: --
3 diseases for MED12L: About MalaCardsusher syndrome type 3 thyroiditis usher syndrome Human Genome Epidemiology (HuGE) Navigator: MED12L (4 documents) Export disorders for MED12L gene to outside databases
|
Publications for MED12L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MED12L gene integrated from 9 sources: (articles sorted by number of sources associating them with MED12L) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Mutations in a novel gene with transmembrane domains underlie Usher syndrome type 3. (PubMed id 11524702)1, 2, 3 Joensuu T.... Sankila E.-M. (2001)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10997877)1, 2 Nagase T.... Ohara O. (2000)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
- Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
- Functional screening of FxxLF-like peptide motifs ide ntifies SMARCD1/BAF60a as an androgen receptor cofactor that modulates TMPRSS2 expression. (PubMed id 19762545)1 van de Wijngaart D.J....Jenster G. (2009)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs. (PubMed id 11483580)2 Yu Y....He F. (2001)
|
External Searches for MED12L gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing MED12L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MED12L gene
(According to HUGE)
About This Section
| |
Specialized Databases showing MED12L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for MED12L | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MED12L gene: Search GeneIP for patents involving MED12L
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for MED12L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for MED12L | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MED12L | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MED12L | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for MED12L | | OriGene 3'-UTR Clone for MED12L | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MED12L | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MED12L | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for MED12L | | OriGene Custom Protein Services for MED12L | | OriGene Custom Immunoassay Development | | |
| |  |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MED12L | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MED12L | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MED12L | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MED12L | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MED12L | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MED12L |
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 |  |  |  | |
| | | Search Tocris compounds for MED12L |
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 | | MED12L Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MED12L |
|  |  |  |  | | | Search ThermoFisher Antibodies for MED12L |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MED12L |
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