Aliases for MED12L Gene
- TRALP 3 4
- Mediator Of RNA Polymerase II Transcription, Subunit 12 Homolog (S. Cerevisiae)-Like 2
- Mediator Of RNA Polymerase II Transcription, Subunit 12 Homolog-Like 3
- Mediator Of RNA Polymerase II Transcription Subunit 12-Like Protein 3
- Mediator Complex Subunit 12-Like Protein 4
- No Opposite Paired Repeat Protein 3
External Ids for MED12L Gene
The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery. [provided by RefSeq, May 2010]
GeneCards Summary for MED12L Gene
MED12L (Mediator Complex Subunit 12-Like) is a Protein Coding gene. Among its related pathways are Thyroid hormone signaling pathway. GO annotations related to this gene include beta-catenin binding and RNA polymerase II transcription cofactor activity. An important paralog of this gene is MED12.
UniProtKB/Swiss-Prot for MED12L Gene
May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).