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ME1 Gene

protein-coding GIFtS: 62

GC06M083977

malic enzyme 1, NADP(+)-dependent, cytosolic
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
EC 1.1.1.40 ^³
HUMNDME ^²
MES ^²
NADP-ME ^³
OTTHUMP00000016792 ^²

Descriptions
Malic enzyme 1 ^³
Malic enzyme, cytoplasmic ^²
NADP-dependent malic enzyme ^²
cytosolic malic enzyme 1 ^²
malate dehydrogenase ^²
malic enzyme 1, NADP(+)-dependent, cytosolic ^²
malic enzyme 1, soluble ^²
pyruvic-malic carboxylase ^²

External Ids
HGNC: 6983¹
Entrez Gene: 4199²
UniProtKB: P48163³
Ensembl: ENSG00000065833⁷

Search outside databases for aliases for ME1 gene

Previous GC identifers: GC06M083867 GC06M083916

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for ME1:

This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid

biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate,

links the glycolytic and citric acid cycles. The regulation of expression for this gene is

complex. Increased expression can result from elevated levels of thyroid hormones or by higher

proportions of carbohydrates in the diet. [provided by RefSeq]

Gene Wiki entry for ME1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ME1 gene

Entrez Gene cytogenetic band: 6q12 Ensembl cytogenetic band: 6q14.2 HGNC cytogenetic band: 6q12

ME1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M083977: (about GC identifiers)

Start:	83,976,827 bp from pter
End:	84,197,498 bp from pter
Size:	220,672 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000006.10 NT_007299.12

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: MAOX_HUMAN, P48163 (See protein sequence)

Recommended Name: NADP-dependent malic enzyme

Size: 572 amino acids; 64150 Da

Cofactor: Divalent metal cations. Prefers magnesium or manganese (By similarity)

Subunit: Homotetramer

Subcellular location: Cytoplasm

PDB structures from and Proteopedia :

2AW5 (3D)

Secondary accessions: Q16797 Q16855 Q53F72 Q5VWA2 Q9BWX8 Q9H1W3 Q9UIY4

REFSEQ proteins: NP_002386.1

ENSEMBL proteins:

ENSP00000358719

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (ME1)
	Human Recombinant Proteins from Abnova (ME1)

OriGene Purified Recombinant Human Protein: ME1

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	18029348
GO:0005730	NOT nucleolus	IDA	18029348
GO:0005737	cytoplasm	IEA	--
GO:0005829	cytosol	ISS	--

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Antibodies for ME1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for ME1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (ME1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ME1)
	Novus Biologicals Antibodies for ME1

Assays for ME1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry P48163

ProtoNet protein and cluster: P48163

1 Blocks protein family: IPB001891 Malic oxidoreductase

UniProtKB/Swiss-Prot: MAOX_HUMAN, P48163

Similarity: Belongs to the malic enzymes family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ME1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ME1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002395

Applied Biosystems Silencer® siRNAs for ME1

Sigma-Aldrich siRNA and siRNA Panels for ME1

Sigma-Aldrich shRNA for ME1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for ME1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_002395
Myc/DDK tagged cDNA clone in CMV expression vector: NM_002395
untagged cDNA clones in CMV expression vector (see all 2): NM_002395

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002395

UniProtKB/Swiss-Prot: MAOX_HUMAN, P48163

Catalytic activity: (S)-malate + NADP(+) = pyruvate + CO(2) + NADPH

Enzyme Number (IUBMB): EC 1.1.1.40

Genatlas biochemistry entry for ME1:

malic enzyme 1,soluble

3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Me1):

homeostasis/metabolism

life span-post-weaning/aging

no phenotypic analysis

5/9 Gene Ontology (GO) molecular function terms (links to tree view) (see all 9 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004473	malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity	ISS	--
GO:0005488	binding	IEA	--
GO:0009055	electron carrier activity	TAS	7622060
GO:0016491	oxidoreductase activity	IEA	--
GO:0030145	manganese ion binding	IDA	7622060

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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2 Sigma-Aldrich "Your Favorite Gene" Pathways for ME1 (Your Favorite Gene powered by Ingenuity)

Pyruvate Metabolism
TR/RXR Activation

GeneDecks ME1 for the pathways selected above

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5/45 Interacting proteins for ME1 (ENSP00000358719³) via UniProtKB, MINT, and/or STRING (see all 45 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
MDH2	ENSP00000327070³	STRING (score=.932)
LDHC	ENSP00000280704³	STRING (score=.903)
MDH1	ENSP00000233114³	STRING (score=.903)
PC	ENSP00000347900³	STRING (score=.9)
ACOX1	ENSP00000301608³	STRING (score=.899)

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5/6 Gene Ontology (GO) biological process terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005975	carbohydrate metabolic process	NAS	8187880
GO:0006108	malate metabolic process	IDA	7622060 8187880
GO:0006741	NADP biosynthetic process	TAS	8187880
GO:0009725	response to hormone stimulus	ISS	--
GO:0009743	response to carbohydrate stimulus	TAS	8187880

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ME1
3 Novoseek chemical compound relationships for ME1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
phosphoenolpyruvate	69.32	5	8704306 (1), 15290293 (1), 16464879 (1), 16228537 (1) (see all 5)
isocitrate	52.22	1	11326687 (1)
pyruvate	48.53	3	12685039 (1), 18445600 (1), 17928289 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ME1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ME1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002395

Sigma-Aldrich siRNA and siRNA Panels for ME1

Sigma-Aldrich shRNA for ME1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002395

REFSEQ mRNAs for ME1 gene:

NM_002395.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002395

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_002395
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_002395
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_002395

Additional cDNA sequence:

AJ420574.1 AK223417.1 AK289783.1 AK301875.1 AK302777.1 BC017403.1 BC025246.1 CR591849.1

CR601714.1 L34035.1 U43944.1 X77244.1

10 DOTS entries:

DT.214180 DT.121372107 DT.92449275 DT.100797729 DT.92449265 DT.100797733 DT.100797737 DT.121372126

DT.95269623 DT.121372118

24/236 AceView cDNA sequences (see all 236 ):

F02108 NM_002395 BG192549 BM720874 AW612304 BG110590 X77244 CB143689

CB120022 CR591849 BQ127991 CB160273 CD108416 BF568564 AI337365 U43944

BX371460 BC025246 T16759 AA927767 CR601714 BU181299 BX488025 AV682650

highest scoring ESTs for ME1:

U43944 AI857682 AL041987 AU279729 AW002307 AW662146 BC025246 BE206224 BF434425 BG764703

Unigene Cluster for ME1:

Malic enzyme 1, NADP(+)-dependent, cytosolic

Hs.21160 [show with all ESTs]

Unigene Representative Sequence: NM_002395

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000369705

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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ME1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ME1

¹ / ² / ³

9 probe-sets matching ME1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
837_s_at²^{, 3}	U95-A	1	1.00	1.00	0.91	1.45	U43944	1.00	1.00	1.00	1
33644_at²^{, 3}	U95-A	1	1.00	1.00	0.67	0.39	L34035	0.80	1.00	0.91	1
31824_at²^{, 3}	U95-A	1	1.00	1.00	0.94	1.22	AL049699	0.20	0.50	0.38	1
204058_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AL049699	0.20	0.50	0.38	1
211204_at²^{, 3}	U133-A	1	1.00	1.00	--	--	L34035	0.80	1.00	0.91	1
204059_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_002395	0.60	1.00	0.82	1
204058_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
211204_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
204059_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks ME1 for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AGACAATTTT

SOURCE GeneReport for Unigene cluster: Hs.21160
Expression variation in blood from EXPOLDB for ME1
UniProtKB/Swiss-Prot: MAOX_HUMAN, P48163
Tissue specificity: Expressed in all tissues tested including liver, placenta and white adipose
tissue

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ME1 gene from 5/19 species (see all 19 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ME1¹	--	malic enzyme 1, NADP(+)-dependent, cytosolic	92.26(n) 93.24(a)	403709 XM_532217.2 XP_532217.2
chimpanzee (Pan troglodytes)	ME1¹	--	malic enzyme 1, NADP(+)-dependent, cytosolic	99.77(n) 99.65(a)	462853 XM_518610.2 XP_518610.2
cow (Bos taurus)	ME1¹	--	malic enzyme 1, NADP(+)-dependent, cytosolic	91.56(n) 92.66(a)	540985 XM_613987.3 XP_613987.3
rat (Rattus norvegicus)	Me1¹	--	malic enzyme 1, NADP(+)-dependent, cytosolic	86.32(n) 90.41(a)	24552 NM_012600.1 NP_036732.1
mouse (Mus musculus)	Me1^{1, 5}	9 (48.00 cM)⁵	malic enzyme 1, NADP(+)-dependent, cytosolic^{1, 5}	86.25(n)¹ 89.34(a)¹	17436¹ NM_008615.1¹ NP_032641.1¹ AK004980⁵ AK006387⁵ (see all 28)

About this table Species with no ortholog for ME1

ENSEMBL Gene Tree for ME1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ME1 gene

ME3² ME2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/1073 NCBI SNPs in ME1 are shown (see all 1073 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 311)

AB	SNP ID	Valid	Chr 6 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs3812142^1,2	A,C,F	84198112(-)	`GGCGAA/GGGTTG`	1	--	ng3¹		2		MN EA	1252
	rs3812144^1,2	A,C,F	84197972(-)	`CCCCTA/CGGTGT`	1	--	ng3¹		2		MN EA	1252
	rs7356974^1,2	C,H	84004169(+)	`TAATCC/TTTTTG`	1	G/R	mis¹ ese³		4		EU EA WA	412
	rs7356975^1,2	C,H	84004220(+)	`TAAACC/TTTCTT`	1	G/S	mis¹ trp³		4		EU EA WA	418
	rs7750800^1,2	F,H	84199474(+)	`TCATAT/CGTAGT`	1	--	ng3¹		4		EU EA WA	416
--	rs2230902^1,2	A,F	84004272(-)	`GCTGGA/GGAGGC`	3	E TE	fra¹ mis¹		0	--	--	--	--
--	rs13202923^1,2	A	83976428(+)	`TATAtA/Tttttt`	1	--	ng5¹		0	--	--	--	--
	rs3812143^1,2	C	84198001(-)	`CCCCTC/GACGAG`	1	--	ng3¹		0	--	--	--	--
	rs1180245^1,2	C	83977603(-)	`TGTCCC/TGAGGT`	1	--	ut3¹ ese³		0	--	--	--	--
	rs4706997^1,2	F	84197445(+)	`GCGCGG/ATRCAG`	1	--	ut5¹ ese³		2		MN EA	1252

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HapMap Linkage Disequilibrium images for ME1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 154250

Genetic Association Database: ME1
Human Genome Epidemiology Navigator: ME1 (3 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/50 PubMed articles for ME1 gene (see all 50 ):

Characterization of cytosolic malic enzyme in human tumor cells. (PubMed id 8187880)^{2, 3, 4} Loeber G.... Ahorn H. (1994)
Cloning, sequencing and functional expression of a cDNA encoding a NADP-dependent malic enzyme from human liver. (PubMed id 7622060)^{1, 3, 4} Gonzalez-Manchon C.... Parrilla R. (1995)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{3, 4} Mungall A.J.... Beck S. (2003)
The interaction between microsomal epoxide hydrolase polymorphisms and cumulative cigarette smoking in different histological subtypes of lung cancer. (PubMed id 11352855)^{3, 6} Zhou W....Christiani D.C. (2001)
Nonidentity of the cDNA sequence of human breast cancer cell malic enzyme to that from the normal human cell. (PubMed id 8804575)^{3, 4} Chou W.Y.... Chang G.G. (1996)
A new locus for autosomal dominant dilated cardiomyopathy identified on chromosome 6q12-q16. (PubMed id 11085912)^{1, 3} Sylvius N....Komajda M. (2001)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)³ Barbe L....Andersson-Svahn H. (2008)
Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. (PubMed id 18660489)³ Lu Y....Boer J.M. (2008)
Determinants of the dual cofactor specificity and substrate cooperativity of the human mitochondrial NAD(P)+-dependent malic enzyme: functional roles of glutamine 362. (PubMed id 16757477)³ Hsieh J.Y....Hung H.C. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 4199	HGNC: 6983	AceView: ME1	Ensembl:ENSG00000065833	euGenes: HUgn4199
ECgene: ME1	H-InvDB: ME1

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
SHMPD	http://shmpd.bii.a-star.edu.sg/gene.php?genestart=A&genename=ME1

Licensable Technologies for ME1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for ME1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ME1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ME1		Antibodies for ME1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ME1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
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	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
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ME1 Gene

protein-coding GIFtS: 62

Aliases &
Descriptions
for ME1

Summaries
for ME1

Genomic Location
for ME1

Proteins
for ME1

Protein Domains/
Families
for ME1

Gene Function
for ME1

Pathways & Interactions
for ME1

Drugs & Compounds
for ME1

Transcripts
for ME1

Expression
for ME1

Orthologs
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SNPs/Variants
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Disorders & Mutations
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Medical News
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Publications
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Genome Databases showing ME1

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Licensable Technologies
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ME1 Gene

protein-coding GIFtS: 62

Aliases & Descriptionsfor ME1

Summariesfor ME1

Genomic Locationfor ME1

Proteinsfor ME1

Protein Domains/Familiesfor ME1

Gene Functionfor ME1

Pathways & Interactionsfor ME1

Drugs & Compoundsfor ME1

Transcriptsfor ME1

Expression for ME1

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Disorders & Mutationsfor ME1

Medical Newsfor ME1

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Genome Databases showing ME1

Other Databases showing ME1

Specialized Databases showing ME1

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ME1

Summaries
for ME1

Genomic Location
for ME1

Proteins
for ME1

Protein Domains/
Families
for ME1

Gene Function
for ME1

Pathways & Interactions
for ME1

Drugs & Compounds
for ME1

Transcripts
for ME1

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