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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MDN1 Gene

protein-coding   GIFtS: 55
GCID: GC06M090352

MDN1, midasin homolog (yeast)

 Explore 2 diseases affiliated with
MDN1 via our new
 Human Malady Compendium 
Biological research products
for MDN1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
MDN1, Midasin Homolog (Yeast)1 2     EC 2.4.2.188
KIAA03011 3     EC 2.7.7.68
MIDAS-Containing Protein2 3     EC 3.6.18
Midasin1     

External Ids:    HGNC: 183021   Entrez Gene: 231952   Ensembl: ENSG000001121597   UniProtKB: Q9NU223   

Export aliases for MDN1 gene to outside databases

Previous GC identifers: GC06M090298 GC06M090348 GC06M090409 GC06M087570


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MDN1_HUMAN, Q9NU22
Function: Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits (By similarity)

Gene Wiki entry for MDN1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007299.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MDN1 gene promoter:
         Nkx5-1   Tal-1beta   Roaz   Arnt   HNF-1A   HNF-1   TGIF   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMDN1 promoter sequence
   Search SABiosciences Chromatin IP Primers for MDN1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MDN1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q15   Ensembl cytogenetic band:  6q15   HGNC cytogenetic band: 6q15

MDN1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MDN1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M090352:  view genomic region     (about GC identifiers)

Start:
90,352,218 bp from pter      End:
90,529,442 bp from pter
Size:
177,225 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MDN1_HUMAN, Q9NU22 (See protein sequence)
Recommended Name: Midasin  
Size: 5596 amino acids; 632820 Da
Subcellular location: Nucleus (By similarity). Nucleus, nucleolus
Secondary accessions: O15019 Q5T794

Explore the universe of human proteins at neXtProt for MDN1: NX_Q9NU22

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NU22

  • 3 DME Specific Peptides for MDN1 (Q9NU22)
     PCRSSLV  GDTGCGK  LDEISLA 

    MDN1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_055426.1  
    ENSEMBL proteins: 
     ENSP00000358400   ENSP00000409664   ENSP00000413970  

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    Browse Sino Biological Recombinant Proteins
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    Uscn Proteins for MDN1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus NAS12102729
    GO:0005730nucleolus IEA--


    MDN1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for MDN1


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    MDN1 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR011704 ATPase_dyneun-rel_AAA
     IPR012099 Midasin
     IPR003593 AAA+_ATPase
     IPR002035 VWF_A

    Graphical View of Domain Structure for InterPro Entry Q9NU22

    ProtoNet protein and cluster: Q9NU22

    2 Blocks protein families:
    IPB002035 Von Willebrand factor type A domain signature
    IPB011704 ATPase associated with various cellular activities


    UniProtKB/Swiss-Prot: MDN1_HUMAN, Q9NU22
    Similarity: Belongs to the midasin family
    Similarity: Contains 1 VWFA domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: MDN1_HUMAN, Q9NU22
    Function: Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits (By similarity)

    Enzyme Numbers (IUBMB): EC 3.6.12 EC 2.7.7.62 EC 2.4.2.182

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidMDN1 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005524ATP binding IEA--
    GO:0016887ATPase activity NAS12102729
    GO:0051082unfolded protein binding NAS12102729


    MDN1 for ontologies           About GeneDecksing


    4 GenomeRNAi human phenotypes for MDN1:
     Decreased Tat-dependent transc  Nuclear 60S biogenesis defects  Synthetic lethal with c-Myc af  Wnt reporter downregulated 

    Animal Models:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Mdn1):
     immune system  mortality/aging 

    MDN1 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Ribosome biogenesis in eukaryotes
    Ribosome biogenesis in eukaryotes1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways



    1         Kegg Pathway  (Kegg details for MDN1):
        Ribosome biogenesis in eukaryotes


    MDN1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MDN1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/856 Interacting proteins for MDN1 (Q9NU222, 3 ENSP000003584004) via UniProtKB, MINT, STRING, and/or I2D (see all 856)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=4 
    HIST1H4BP628053I2D: score=4 
    HIST1H4CP628053I2D: score=4 
    HIST1H4DP628053I2D: score=4 
    HIST1H4EP628053I2D: score=4 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006200ATP catabolic process NAS12102729
    GO:0006461protein complex assembly NAS12102729


    MDN1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MDN1
    Search CenterWatch for drugs/clinical trials and news about MDN1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MDN1 gene: 
    NM_014611.1  

    Unigene Cluster for MDN1:

    MDN1, midasin homolog (yeast)
    Hs.529948  [show with all ESTs]
    Unigene Representative Sequence: AF503925
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000369393(uc003pnn.1) ENST00000487831 ENST00000468568 ENST00000439638
    ENST00000428876(uc003pno.1 uc003pnp.1)

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    hsa-miR-204 hsa-miR-3714 hsa-miR-4287 hsa-miR-211
    SwitchGear 3'UTR luciferase reporter plasmidMDN1 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MDN1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MDN1

    Additional cDNA sequence: 

    AB002299.2 AF503925.1 AK027048.1 AK098453.1 AK123109.1 AK124025.1 AK125181.1 BC014882.2 
    BC020432.1 BC036888.1 CR627399.1 

    21 DOTS entries:

    DT.416515  DT.91748145  DT.95098521  DT.99974319  DT.40208140  DT.205489  DT.121383974  DT.40254890 
    DT.95271645  DT.86841154  DT.100008614  DT.100666849  DT.100789301  DT.100789302  DT.102838109  DT.65286765 
    DT.75103782  DT.91983044  DT.95257456  DT.95271643  DT.416963 

    24/235 AceView cDNA sequences (see all 235):

    BQ923756 AI633939 BG942924 AI424987 AI133682 BM456078 CK300312 BM977350 
    AU125556 C04730 BE858085 BF195855 BE792924 BX111329 AL135200 BQ287975 
    AK125181 BX500874 AI360878 CR627399 AA369698 BQ437357 BQ073374 AI923602 

    GeneLoc Exon Structure

    5/16 Alternative Splicing Database (ASD) splice patterns (SP) for MDN1 (see all 16)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^
    SP1:                                                                                                                                                            
    SP2:                                                                          -                                                                                 
    SP3:                    -                                                                                                                                       
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30a · 30b ^ 31 ^ 32 ^ 33 ^ 34a · 34b ^ 35 ^ 36 ^ 37 ^ 38 ^ 39 ^ 40 ^ 41 ^ 42 ^ 43 ^ 44 ^ 45 ^ 46 ^ 47 ^ 48 ^
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                  -                                                                                                         

    ExUns: 49 ^ 50 ^ 51a · 51b ^ 52a · 52b ^ 53 ^ 54a · 54b ^ 55a · 55b ^ 56a · 56b ^ 57 ^ 58 ^ 59 ^ 60 ^ 61 ^ 62 ^ 63 ^ 64 ^ 65 ^ 66 ^ 67 ^ 68 ^ 69 ^
    SP1:  -                       -                                                                                                                                 
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                    -                                                                                       
    SP5:                                                                                                                                                            

    ExUns: 70a · 70b ^ 71a · 71b · 71c ^ 72a · 72b ^ 73a · 73b · 73c ^ 74 ^ 75a · 75b ^ 76 ^ 77 ^ 78 ^ 79 ^ 80 ^ 81 ^ 82 ^ 83 ^ 84 ^ 85 ^ 86 ^ 87a · 87b ·
    SP1:  -           -                 -                                   -                                                                       -               
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            


    ECgene alternative splicing isoforms for MDN1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MDN1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See MDN1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MDN1

    SOURCE GeneReport for Unigene cluster: Hs.529948
        SABiosciences Custom PCR Arrays for MDN1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MDN1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MDN1 gene from 10/32 species (see all 32)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mdn11 , 5 midasin homolog (yeast)1, 5 83.96(n)1
    82.92(a)1
      4 (14.30 cM)5
    1000191  NM_001081392.11  NP_001074861.11 
     326571195 
    chicken
    (Gallus gallus)
    Aves MDN11 MDN1, midasin homolog (yeast) 69.82(n)
    68.97(a)
      421811  XM_419835.3  XP_419835.3 
    lizard
    (Anolis carolinensis)
    Reptilia MDN16
    --
    66(a)
    1 ↔ 1
    1(174677584-174809187)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.257152 Xenopus laevis transcribed sequence with weak similarity more 76(n)    BJ084735.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mdn11 midasin homolog (yeast) 60.25(n)
    57.91(a)
      555704  XM_003200703.1  XP_003200751.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG131851 , 3 CG131851 32(a)3
    46.94(n)1
    38.36(a)1
      362681  NM_001103809.11  NP_001097279.11 
    worm
    (Caenorhabditis elegans)
    Secernentea F55F10.13   -- 38(a)   IV(4361048-4386449)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MDN1(YLR106C)4
    MDN11
    Huge dynein-related AAA-type ATPase (midasin), forms more4
    Mdn1p1
    47.92(n)1
    38.44(a)1
      12(363738-349006)4
    8507961, 4  NP_013207.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G671206
    AAA ATPase containing von Willebrand factor type A...
    26(a)
    1 ↔ 1
    1(25069562-25095526)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    midasin-related, putative, expressed
    29(a)
    23(a)
    1 ↔ 1
    possible ortholog
    10(16645003-16671307)
    10(16638950-16644310)


    ENSEMBL Gene Tree for MDN1 (if available)
    TreeFam Gene Tree for MDN1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2953 NCBI SNPs in MDN1 are shown (see all 2953    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1893180001,2
    --90352791(+) CCAAGC/TAAAAA 1 -- ds50010--------
    rs94512581,2
    H--90352828(+) TGGAAA/TAAATA 1 -- ds50014Minor allele frequency- T:0.00NS EA 414
    rs76821,2
    C,F,H,--90352862(-) AGAAAC/TGCTGT 1 -- ds5001 ese310Minor allele frequency- T:0.05MN EA NS NA WA 2324
    rs1390903031,2
    --90353208(+) TCACAA/GTAAGA 1 -- ds50010--------
    rs1808051521,2
    --90353352(+) GGACTA/GTCAGA 1 -- ut310--------
    rs1427141151,2
    --90353370(+) CTCCT-/GGGCAG 1 -- ut310--------
    rs1499407081,2
    --90353383(+) TCTCCG/TCAAGG 1 -- ut310--------
    rs1861852871,2
    --90353478(+) CAAGGC/TAGGGA 1 -- ut310--------
    rs1919471251,2
    --90353508(+) AGTTAC/TGAGTT 1 -- ut310--------
    rs177357871,2
    C--90353523(+) CACCTG/CCTGCT 1 -- ut31 ese33Minor allele frequency- C:0.01NA 138

    HapMap Linkage Disequilibrium report for MDN1 (90352218 - 90529442 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for MDN1: --
    Human Gene Mutation Database (HGMD): MDN1

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MDN1
    DNA2.0 Custom Variant and Variant Library Synthesis for MDN1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    MDN1 for disorders           About GeneDecksing

    2 diseases for MDN1:    About MalaCards
    fanconi's anemia    anemia

    Human Genome Epidemiology (HuGE) Navigator: MDN1 (2 documents)

    Export disorders for MDN1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MDN1 gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with MDN1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Expression and genomic analysis of midasin, a novel and highly conserved AAA protein distantly related to dynein. (PubMed id 12102729)1, 2, 3 Garbarino J.E. and Gibbons I.R. (2002)
    2. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2, 3 Nagase T.... Ohara O. (1997)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
    7. Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization. (PubMed id 22002106)2 Ahmad Y.... Lamond A.I. (2012)
    8. NOTCH1 nuclear interactome reveals key regulators of i ts transcriptional activity and oncogenic function. (PubMed id 23022380)1 Yatim A....Benkirane M. (2012)
    9. Maintenance of silent chromatin through replication r equires SWI/SNF-like chromatin remodeler SMARCAD1. (PubMed id 21549307)1 Rowbotham S.P....Mermoud J.E. (2011)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23195 HGNC: 18302 AceView: MDN1 Ensembl:ENSG00000112159 euGenes: HUgn23195
    ECgene: MDN1 Kegg: 23195 H-InvDB: MDN1

    (According to HUGE)
    About This Section
    HUGE: KIAA0301

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MDN1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MDN1 gene:
    Search GeneIP for patents involving MDN1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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