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MDH1B Gene

protein-coding   GIFtS: 43
GCID: GC02M207602

Malate Dehydrogenase 1B, NAD (Soluble)

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Malate Dehydrogenase 1B, NAD (Soluble)1 2
RP11-95H112
Putative Malate Dehydrogenase 1B2
EC 1.1.1.-3

External Ids:    HGNC: 178361   Entrez Gene: 1307522   Ensembl: ENSG000001384007   UniProtKB: Q5I0G33   

Export aliases for MDH1B gene to outside databases

Previous GC identifers: GC00U991156 GC02M207805 GC02M207428 GC02M207310 GC02M199451


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MDH1B Gene:
MDH1B (malate dehydrogenase 1B, NAD (soluble)) is a protein-coding gene. GO annotations related to this gene include malate dehydrogenase activity and oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. An important paralog of this gene is MDH1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MDH1B gene promoter:
         HSF1 (long)   CUTL1   Cdc5   C/EBPalpha   AREB6   POU2F1   POU2F1a   HFH-1   Sox9   Ik-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for MDH1B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MDH1B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q33.3   Ensembl cytogenetic band:  2q33.3   HGNC cytogenetic band: 2q33.3

MDH1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MDH1B gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M207602:  view genomic region     (about GC identifiers)

Start:
207,602,487 bp from pter      End:
207,630,271 bp from pter
Size:
27,785 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: MDH1B_HUMAN, Q5I0G3 (See protein sequence)
Recommended Name: Putative malate dehydrogenase 1B  
Size: 518 amino acids; 58651 Da
Secondary accessions: A8K8M1 Q53TK9 Q8IV51
Alternative splicing: 3 isoforms:  Q5I0G3-1   Q5I0G3-2   Q5I0G3-3   (Ref.4 (AAH33509) sequence is in conflict in position: 261:I->T)

Explore the universe of human proteins at neXtProt for MDH1B: NX_Q5I0G3

Explore proteomics data for MDH1B at MOPED


See MDH1B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts): 
NP_001034934.1  NP_001269869.1  

ENSEMBL proteins: 
 ENSP00000363533   ENSP00000392464   ENSP00000416577   ENSP00000389916   ENSP00000403810  
 ENSP00000376049  

MDH1B Human Recombinant Protein Products:

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Novus Biologicals MDH1B Protein
Novus Biologicals MDH1B Lysates
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Cloud-Clone Corp. Proteins for MDH1B

 
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antibodies-online proteins for MDH1B (5 products) 

 
antibodies-online peptides for MDH1B

MDH1B Antibody Products:

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antibodies-online antibodies for MDH1B (13 products) 

MDH1B Assay Products:

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GenScript Custom Assay Services for MDH1B
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Cloud-Clone Corp. ELISAs for MDH1B
Cloud-Clone Corp. CLIAs for MDH1B
Search eBioscience for ELISAs for MDH1B 
antibodies-online kits for MDH1B (3 products) 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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4 InterPro protein domains:
 IPR010945 Malate_DH_type2
 IPR022383 Lactate/malate_DH_C
 IPR015955 Lactate_DH/Glyco_Ohase_4_C
 IPR016040 NAD(P)-bd_dom

Graphical View of Domain Structure for InterPro Entry Q5I0G3

ProtoNet protein and cluster: Q5I0G3

1 Blocks protein domain: IPB008267 Malate dehydrogenase

UniProtKB/Swiss-Prot: MDH1B_HUMAN, Q5I0G3
Similarity: Belongs to the LDH/MDH superfamily. MDH type 2 family


Find genes that share domains with MDH1B           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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     Enzyme Number (IUBMB): EC 1.1.1.-1

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003824catalytic activity ----
GO:0016615malate dehydrogenase activity IEA--
GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA--
     
Find genes that share ontologies with MDH1B           About GenesLikeMe


Animal Models:
   genOway: Develop your customized and physiologically relevant rodent model for MDH1B

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat MDH1B using miScript Target Protectors
3 qRT-PCR Assays for microRNAs that regulate MDH1B:
hsa-miR-146a* hsa-miR-549 hsa-miR-607
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for MDH1B
Predesigned siRNA for gene silencing in human, mouse, rat MDH1B

Gene Editing
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Clone
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OriGene clones in human, mouse for MDH1B (see all 6)
OriGene ORF clones in mouse, rat for MDH1B
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: MDH1B (NM_001039845)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for MDH1B
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MDH1B

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MDH1B


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytosol2
nucleus2
cytoskeleton1
extracellular1
golgi apparatus1
mitochondrion1
peroxisome1

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Pathway & Disease-focused RT2 Profiler PCR Arrays including MDH1B: 
          Molecular Toxicology PathwayFinder 384HT in human mouse rat
          Glucose Metabolism in human mouse rat

Interactions:

    Search GeneGlobe Interaction Network for MDH1B

STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

Selected Interacting proteins for MDH1B (ENSP000003635334) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
InteractantInteraction Details
GeneCardExternal ID(s)
CCNHENSP000002568974STRING: ENSP00000256897
RAE1ENSP000003602864STRING: ENSP00000360286
CYC1ENSP000003171594STRING: ENSP00000317159
ATP5A1ENSP000002820504STRING: ENSP00000282050
IDH1ENSP000002609854STRING: ENSP00000260985
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Gene Ontology (GO): 4 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005975carbohydrate metabolic process IEA--
GO:0006099tricarboxylic acid cycle IEA--
GO:0006108malate metabolic process IEA--
GO:0055114oxidation-reduction process ----

Find genes that share ontologies with MDH1B           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for MDH1B



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for MDH1B gene (3 alternative transcripts): 
NM_206892.1  NM_001039845.2  NM_001282940.1  

Unigene Cluster for MDH1B:

Malate dehydrogenase 1B, NAD (soluble)
Hs.147816  [show with all ESTs]
Unigene Representative Sequence: NM_001039845
7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000374412(uc010ziw.2 uc002vbs.3 uc010fui.3) ENST00000432911(uc002vbt.3)
ENST00000449792(uc021vvm.1) ENST00000454776 ENST00000436472 ENST00000471988
ENST00000392214
miRNA
Products:
     
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3 qRT-PCR Assays for microRNAs that regulate MDH1B:
hsa-miR-146a* hsa-miR-549 hsa-miR-607
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for MDH1B
Predesigned siRNA for gene silencing in human, mouse, rat MDH1B
Clone
Products:
     
OriGene clones in human, mouse for MDH1B (see all 6)
OriGene ORF clones in mouse, rat for MDH1B
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: MDH1B (NM_001039845)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for MDH1B
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MDH1B
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for MDH1B
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MDH1B
  QuantiTect SYBR Green Assays in human, mouse, rat MDH1B
  QuantiFast Probe-based Assays in human, mouse, rat MDH1B

Additional mRNA sequence: 

AK058070.1 AK292378.1 AK292386.1 AK302250.1 AK308257.1 AK309144.1 BC033509.1 BC088356.1 

5 DOTS entries:

DT.40206723  DT.92003755  DT.86847255  DT.91707010  DT.120991682 

Selected AceView cDNA sequences (see all 41):

AI783669 AK058070 CR593018 AI076012 BM717644 BF221699 BF056314 BF979825 
BC033509 CD251991 CD104917 NM_206892 AA889831 BU844500 BX371624 BX098360 
AW118920 AA758811 N66501 AI221878 BX369192 AI025196 BX369191 BF197105 

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for MDH1B    About this scheme

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12
SP1:                          -                                   -                     
SP2:                          -     -     -                                             
SP3:                          -     -     -                                             
SP4:                                                                                    


ECgene alternative splicing isoforms for MDH1B

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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MDH1B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
MDH1B Expression
About this image

MDH1B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

MDH1B Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.147816
    Pathway & Disease-focused RT2 Profiler PCR Arrays including MDH1B: 
          Molecular Toxicology PathwayFinder 384HT in human mouse rat
          Glucose Metabolism in human mouse rat

Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for MDH1B
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MDH1B
QuantiTect SYBR Green Assays in human, mouse, rat MDH1B
QuantiFast Probe-based Assays in human, mouse, rat MDH1B
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MDH1B

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for MDH1B gene from Selected species (see all 14)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Mdh1b1 , 5 malate dehydrogenase 1B, NAD (soluble)1, 5 77.16(n)1
72.19(a)1
  1 (32.31 cM)5
766681  NM_029696.41  NP_083972.31 
 636988195 
chicken
(Gallus gallus)
Aves MDH1B1 malate dehydrogenase 1B, NAD (soluble) 63.26(n)
57.14(a)
  424097  XM_421952.4  XP_421952.1 
lizard
(Anolis carolinensis)
Reptilia MDH1B6
malate dehydrogenase 1B, NAD (soluble)
52(a)
1 ↔ 1
GL343208.1(345990-372301)
tropical clawed frog
(Xenopus tropicalis)
Amphibia mdh1b1 malate dehydrogenase 1B, NAD (soluble) 60.25(n)
49.28(a)
  100490547  XM_002937125.2  XP_002937171.2 
zebrafish
(Danio rerio)
Actinopterygii zgc:1539221 zgc:153922 55.34(n)
47.92(a)
  767794  NM_001076761.1  NP_001070229.1 
fruit fly
(Drosophila melanogaster)
Insecta Mdh16
Malate dehydrogenase 1
26(a)
1 → many
2L(10393847-10396275)
worm
(Caenorhabditis elegans)
Secernentea mdh-16
Protein MDH-1, isoform a
26(a)
1 → many
V(6515276-6516526) WBGene00018491


ENSEMBL Gene Tree for MDH1B (if available)
TreeFam Gene Tree for MDH1B (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for MDH1B gene
MDH12  
1 SIMAP similar gene for MDH1B using alignment to 3 protein entries:     MDH1B_HUMAN (see all proteins):
MDH1

Find genes that share paralogs with MDH1B           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for MDH1B (see all 626)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 2 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1436312111,2
--207601992(+) TCTGCA/GTAAAG 1 -- ds50010--------
rs46756331,2
C,F,A,H--207602049(+) CTTGGG/ATTGAG 1 -- ds500113Minor allele frequency- A:0.38NA WA CSA EA 515
rs1480861661,2
--207602050(+) TTGGGC/TTGAGG 1 -- ds50010--------
rs1419096721,2
--207602104(+) AAATCA/GATGTC 1 -- ds50010--------
rs557142161,2
C,F--207602117(+) TAACAC/TGGATA 1 -- ds50012Minor allele frequency- T:0.15WA 120
rs1460849251,2
--207602216(+) TATGAA/TGGTGC 1 -- ds50010--------
rs1389737631,2
C--207602234(+) ATGCAA/GAAGAT 1 -- ds50010--------
rs1147464341,2
C,F--207602299(+) AAACAT/CACAGA 1 -- ds50011Minor allele frequency- C:0.07WA 118
rs21938841,2
C,F,A,H--207602424(-) AAAGCA/GGTAAT 1 -- ds500123Minor allele frequency- G:0.48NS EA NA WA CSA 3837
rs1833161821,2
--207602851(+) CCACTC/TAGGTG 1 -- ut310--------

HapMap Linkage Disequilibrium report for MDH1B (207602487 - 207630271 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for MDH1B:    About this table    
Variant IDTypeSubtypePubMed ID
nsv875739CNV Gain21882294

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing MDH1B
DNA2.0 Custom Variant and Variant Library Synthesis for MDH1B

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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Find genes that share disorders with MDH1B           About GenesLikeMe

Genetic Association Database (GAD): MDH1B
Human Genome Epidemiology (HuGE) Navigator: MDH1B (1 document)

Export disorders for MDH1B gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for MDH1B gene integrated from 10 sources:
(articles sorted by number of sources associating them with MDH1B)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
  2. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. (PubMed id 21248752)2 Varela I....Futreal P.A. (Nature 2011)
  3. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PubMed id 17903301)4 Vasan R.S....Benjamin E.J. (BMC Med. Genet. 2007)
  4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
  7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 130752 HGNC: 17836 AceView: MDH1B Ensembl:ENSG00000138400 euGenes: HUgn130752
ECgene: MDH1B H-InvDB: MDH1B

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for MDH1B Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for MDH1B gene:
Search GeneIP for patents involving MDH1B

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for MDH1B  
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 Block miRNA regulation of human, mouse, rat MDH1B using miScript Target Protectors SeqTarget long-range PCR primers for resequencing MDH1B
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 Search Tocris compounds for MDH1B
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 Novus Tissue Slides
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 Search for Antibodies for MDH1B at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for MDH1B
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 Browse ESI BIO Cell Lines and PureStem Progenitors for MDH1B
 Gene Synthesis
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 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MDH1B
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 Search ThermoFisher Antibodies for MDH1B
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MDH1B
 Browse compounds at ApexBio
 Search Addgene for plasmids for MDH1B
  Search eBioscience for proteins for MDH1B
  Search eBioscience for elisas for MDH1B
  eBioscience FlowRNA Probe Sets
 genOway: Develop your customized and physiologically relevant rodent model for MDH1B
 antibodies-online antibodies for MDH1B (13 products)
 antibodies-online kits for MDH1B (3 products)
 antibodies-online peptides for MDH1B
 antibodies-online proteins for MDH1B (5 products)
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

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