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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MDGA1 Gene

protein-coding   GIFtS: 49
GCID: GC06M037598

MAM domain containing glycosylphosphatidylinositol anchor...
 Explore 3 diseases affiliated with
MDGA1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for MDGA1    

Aliases
for MDGA1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
MAM Domain Containing Glycosylphosphatidylinositol Anchor 11 2     Glycosyl-Phosphatidyl-Inositol-MAM1
GPIM1 2 3 5     Glycosylphosphatidylinositol-MAM3
MAMDC31 2 3     MAM Domain-Containing Glycosylphosphatidylinositol Anchor Protein 12
GPI And MAM Protein2 3     Glycosylphosphatidylinositol-MAM3
MAM Domain-Containing Protein 32 3     

External Ids:    HGNC: 192671   Entrez Gene: 2667272   Ensembl: ENSG000001121397   OMIM: 6096265   UniProtKB: Q8NFP43   

Export aliases for MDGA1 gene to outside databases

Previous GC identifers: GC06U990326 GC06M037596 GC06M037647 GC06M037708 GC06M037319


Summaries
for MDGA1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: MDGA1_HUMAN, Q8NFP4
Function: Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity)




Genomic Views
for MDGA1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MDGA1 gene promoter:
         E2F-4   E2F-3a   USF1   E2F-5   Elk-1   MAZR   AP-4   E2F-2   E2F   E2F-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MDGA1 promoter sequence
   Search SABiosciences Chromatin IP Primers for MDGA1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MDGA1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21   Ensembl cytogenetic band:  6p21.2   HGNC cytogenetic band: 6p21

MDGA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MDGA1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M037598:  view genomic region     (about GC identifiers)

Start:
 37,598,455 bp from pter      End:
 37,667,082 bp from pter
Size:
 68,628 bases      Orientation:
 minus strand

Proteins
for MDGA1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: MDGA1_HUMAN, Q8NFP4 (See protein sequence)
Recommended Name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor  
Size: 955 amino acids; 105790 Da
Subunit: Interacts heterophilically through its MAM domain with proteins in axon-rich regions and through its Ig-like
domains with proteins in differentiating muscle (By similarity)
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor. Note=Associated with lipid rafts
Sequence caution: Sequence=BAC03502.1; Type=Erroneous initiation;
Secondary accessions: A6NHG0 Q8NBE3
Alternative splicing: 2 isoforms:  Q8NFP4-1   Q8NFP4-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MDGA1: NX_Q8NFP4

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8NFP4

    • MDGA1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_705691.1  
    ENSEMBL proteins: 
     ENSP00000402584   ENSP00000422042   ENSP00000393330   ENSP00000425911   ENSP00000421510  
     ENSP00000427645   ENSP00000297153  

    Human Recombinant Protein Products: 
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    R&D Systems Recombinant & Natural Proteins for MDGA1
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    OriGene Protein Over-expression Lysate: MDGA1
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    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for MDGA1

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0046658anchored to plasma membrane ISS15019943


    MDGA1 for ontologies           About GeneDecksing



    MDGA1 Antibody Products: 
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    Assay Products for MDGA1: 
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    Uscn ELISAs and CLIAs for MDGA1

    Protein Domains /
    Families
    for MDGA1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    MDGA1 for domains           About GeneDecksing

    5/8 InterPro domains/families (see all 8):
     IPR003598 Ig_sub2
     IPR003961 Fibronectin_type3
     IPR013098 Ig_I-set
     IPR013783 Ig-like_fold
     IPR007110 Ig-like_dom

    Graphical View of Domain Structure for InterPro Entry Q8NFP4

    ProtoNet protein and cluster: Q8NFP4

    3 Blocks protein families:
    IPB000998 MAM domain signature
    IPB003598 Immunoglobulin C-2 type
    IPB003599 Immunoglobulin subtype


    UniProtKB/Swiss-Prot: MDGA1_HUMAN, Q8NFP4
    Similarity: Contains 1 fibronectin type-III domain
    Similarity: Contains 6 Ig-like (immunoglobulin-like) domains
    Similarity: Contains 1 MAM domain


    Function
    for MDGA1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: MDGA1_HUMAN, Q8NFP4
    Function: Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity)

    miRNA
    Products:            		miRTarBase miRNAs that target MDGA1:
    hsa-mir-210 (MIRT003161)

    OriGene 3'-UTR Clone: MDGA1
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MDGA1
    8/86 QIAGEN miScript miRNA Assays for microRNAs that regulate MDGA1 (see all 86):
    hsa-miR-3607-3p hsa-miR-200a hsa-miR-134 hsa-miR-128 hsa-miR-3138 hsa-miR-877* hsa-miR-629* hsa-miR-509-3-5p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MDGA1 (see all 6)
    OriGene siRNA: MDGA1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MDGA1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for MDGA1

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MDGA1 (see all 3)
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: MDGA1 (NM_153487)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MDGA1 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for MDGA1
    Search LifeMap BioReagents cell lines for MDGA1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MDGA1

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--


    MDGA1 for ontologies           About GeneDecksing


    Animal Models:
         2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Mdga1):
     cellular  nervous system 

    MDGA1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for MDGA1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MDGA1

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001764neuron migration ISS--
    GO:0007420brain development ISS15019943
    GO:0021527spinal cord association neuron differentiation ISS15019943


    MDGA1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for MDGA1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MDGA1
    Search CenterWatch for drugs/clinical trials and news about MDGA1 

    Transcripts
    for MDGA1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for MDGA1 gene: 
    NM_153487.3  

    Unigene Cluster for MDGA1:

    MAM domain containing glycosylphosphatidylinositol anchor 1
    Hs.437993  [show with all ESTs]
    Unigene Representative Sequence: AF478693
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000434837(uc003onu.1 uc003onv.1) ENST00000373401 ENST00000505425
    ENST00000503419 ENST00000418178 ENST00000502298 ENST00000510077 ENST00000478143
    ENST00000515437 ENST00000508399 ENST00000297153

    miRNA
    Products:             		 OriGene 3'-UTR Clone: MDGA1
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MDGA1
    8/86 QIAGEN miScript miRNA Assays for microRNAs that regulate MDGA1 (see all 86):
    hsa-miR-3607-3p hsa-miR-200a hsa-miR-134 hsa-miR-128 hsa-miR-3138 hsa-miR-877* hsa-miR-629* hsa-miR-509-3-5p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MDGA1 (see all 6)
    OriGene siRNA: MDGA1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MDGA1
    Clone
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    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MDGA1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MDGA1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MDGA1

    Additional cDNA sequence: 

    AF478693.1 AK055376.1 AK091650.1 AK092308.1 AK126965.1 BX647180.1 BX647253.1 

    7 DOTS entries:

    DT.40113406  DT.101973692  DT.100022137  DT.100755333  DT.100022135  DT.204494  DT.40313562 

    24/81 AceView cDNA sequences (see all 81):

    AA481631 AW014039 AF478693 BP344579 BX101256 NM_153487 AA325266 AK091149 
    AI813394 CK300811 AI827393 AW593235 R88808 AW003899 AX746808 AX746568 
    BF195188 BX647180 BU620610 BM673820 BE730067 AK055376 AI276717 AK126965 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for MDGA1 (see all 12)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13a · 13b · 13c ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18a ·
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                                  -     -   
    SP3:        -                                                                                                                                                   
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 18b · 18c ^ 19 ^ 20a · 20b · 20c
    SP1:                                    
    SP2:                                    
    SP3:                                    
    SP4:                                    
    SP5:                                    


    ECgene alternative splicing isoforms for MDGA1

    Expression
    for MDGA1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MDGA1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TCTGACCACC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    MDGA1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    6 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Spinal CordSpinal Dorsal ColumnsDorsal Spinal Cord Progenitor CellsSpinal Cord
    Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor CellsMotor Neurons
    BrainMedulla OblongataBrain
    Neural TubeMetencephalonNeural Tube
    Spinal CordSpinal Dorsal ColumnsSpinal Cord
    Spinal CordSpinal Ventral ColumnsSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See MDGA1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MDGA1

    SOURCE GeneReport for Unigene cluster: Hs.437993

    UniProtKB/Swiss-Prot: MDGA1_HUMAN, Q8NFP4
    Tissue specificity: Has been found in brain, heart, skeletal muscle and kidney. Found to be overexpressed in tumor
    tissues

        SABiosciences Custom PCR Arrays for MDGA1
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MDGA1

    Orthologs
    for MDGA1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for MDGA1 gene from 4/14 species (see all 14)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves MDGA11 MAM domain containing glycosylphosphatidylinositol anchor 1 less 74.64(n)
    79.45(a)    		   421431  NM_001044647.1  NP_001038112.1 
    lizard
    (Anolis carolinensis)    		 Reptilia MDGA16
    		 --
    		 76(a)
    		 possible ortholog
    		 1(228758968-229100355)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.135492 Xenopus laevis transcribed sequence with weak similarity to protein pirI49583 (M.musculus) I49583 differentiation antigen - mouse less 72.51(n)    BJ057835.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii LOC5691801 MAM domain-containing glycosylphosphatidylinositol anchor protein 1-like less 65.54(n)
    63.33(a)    		   569180  XM_692548.5  XP_697640.5 


    ENSEMBL Gene Tree for MDGA1 (if available)
    TreeFam Gene Tree for MDGA1 (if available) 

    Paralogs
    for MDGA1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MDGA1 gene
    MAMDC42  MDGA22  C10orf1122  MAMDC22  
    7 SIMAP similar genes for MDGA1 using alignment to 7 protein entries:     MDGA1_HUMAN (see all proteins):
    MDGA2    NRP1    L1CAM    MUSK    DCC    NFASC
    LSAMP

    MDGA1 for paralogs           About GeneDecksing



    Genomic Variants
    for MDGA1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1295 NCBI SNPs in MDGA1 are shown (see all 1295)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1930385341,2
    		--37599786(+) TCCTTA/GAGCCT 1 -- ds50010--------
    rs1857809301,2
    		--37599853(+) CTCTCC/TCAATC 1 -- ds50010--------
    rs1872204551,2
    		--37599947(+) CCTCTC/TCATAC 1 -- ds50010--------
    rs69267351,2
    		C,F,A,H,--37599962(+) TTTCAT/CAGCAC 1 -- ds500119Minor allele frequency- C:0.25NS EA WA NA 2756
    rs773116661,2
    		F,--37599985(+) CCAGCC/TCTCAC 1 -- ds50011Minor allele frequency- T:0.04WA 118
    rs1112448461,2
    		C,--37599995(+) CTGTAC/TACATC 1 -- ds50011Minor allele frequency- T:0.50NA 2
    rs1455934551,2
    		C,--37600107(+) AATGC-/ACGAGG
                ACACA     		1 -- ds50010--------
    rs611510791,2
    		C--37600109(+) TGCAC-/GAGGAC
                ACAAG     		1 -- ds50010--------
    rs69270741,2
    		C,F,A,H,--37600120(+) TTCACT/CGGGAG 1 -- ds50017Minor allele frequency- C:0.24NS EA WA NA 778
    rs752896151,2
    		F,--37600172(+) GGATCC/TCTGTC 1 -- ds50011Minor allele frequency- T:0.03WA 118

    HapMap Linkage Disequilibrium report for MDGA1 (37598455 - 37667082 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for MDGA1
         2 CNVs: 69491 8512

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MDGA1
    DNA2.0 Custom Variant and Variant Library Synthesis for MDGA1

    Disorders / Diseases
    for MDGA1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    MDGA1 for disorders           About GeneDecksing

    OMIM gene information: 609626    OMIM disorders: --

    3 diseases for MDGA1:    About MalaCards
    bipolar disorder    schizophrenia    neuronitis

    Human Genome Epidemiology (HuGE) Navigator: MDGA1 (4 documents)

    Export disorders for MDGA1 gene to outside databases

    Publications
    for MDGA1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MDGA1 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with MDGA1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of MDGA1, a novel human glycosylphosphatidylinositol-anchored protein localized in lipid rafts. (PubMed id 15922729)1, 2, 3 Diaz-Lopez A....De Juan C. (2005)
    2. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (2005)
    3. Identification and characterization of two novel brain-derived immunoglobulin superfamily members with a unique structural organization. (PubMed id 15019943)1, 3 Litwack E.D....O'Leary D.D. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Genomic organization of a novel glycosylphosphatidylinositol MAM gene expressed in human tissues and tumors. (PubMed id 12082541)1, 2 De Juan C.... Benito M. (2002)
    6. Proteomics strategy to identify substrates of LNX, a P DZ domain-containing E3 ubiquitin ligase. (PubMed id 22889411)1 Guo Z....Gao Y. (2012)
    7. The MDGA1 gene confers risk to schizophrenia and bipo lar disorder. (PubMed id 21146959)1 Li J....Shi Y. (2011)
    8. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    9. WITHDRAWN: Common polymorphisms in the MDGA1 gene are associated with bipolar disorder and schizophrenia in the Chinese Han populati on. (PubMed id 20036297)1 Li J....Shi Y. (2009)
    10. Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene. (PubMed id 18384059)1 Kahler A.K....Andreassen O.A. (2008)

    External Searches for MDGA1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Genome Databases showing MDGA1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 266727 HGNC: 19267 AceView: MDGA1 Ensembl:ENSG00000112139 euGenes: HUgn266727
    ECgene: MDGA1 H-InvDB: MDGA1

    Other Databases showing MDGA1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing MDGA1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MDGA1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for MDGA1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for MDGA1 gene:
    Search GeneIP for patents involving MDGA1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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