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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MDGA1 Gene

protein-coding GIFtS: 49
GCID: GC06M037598

MAM domain containing glycosylphosphatidylinositol anchor...

Explore 3 diseases affiliated with
MDGA1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
MAM Domain Containing Glycosylphosphatidylinositol Anchor 1¹ ²		Glycosyl-Phosphatidyl-Inositol-MAM¹
GPIM¹ ² ³ ⁵		Glycosylphosphatidylinositol-MAM³
MAMDC3¹ ² ³		MAM Domain-Containing Glycosylphosphatidylinositol Anchor Protein 1²
GPI And MAM Protein² ³		Glycosylphosphatidylinositol-MAM³
MAM Domain-Containing Protein 3² ³

External Ids:	HGNC: 19267¹	Entrez Gene: 266727²	Ensembl: ENSG00000112139⁷	OMIM: 609626⁵	UniProtKB: Q8NFP4³

Export aliases for MDGA1 gene to outside databases

Previous GC identifers: GC06U990326 GC06M037596 GC06M037647 GC06M037708 GC06M037319

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MDGA1_HUMAN, Q8NFP4

Function: Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000006.11 NC_018917.1 NT_007592.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the MDGA1 gene promoter:
E2F-4 E2F-3a USF1 E2F-5 Elk-1 MAZR AP-4 E2F-2 E2F E2F-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MDGA1 promoter sequence

Search SABiosciences Chromatin IP Primers for MDGA1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MDGA1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21 Ensembl cytogenetic band: 6p21.2 HGNC cytogenetic band: 6p21

MDGA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MDGA1 gene location

GeneLoc information about chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M037598: view genomic region (about GC identifiers)

Start:	37,598,455 bp from pter	End:	37,667,082 bp from pter
Size:	68,628 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MDGA1_HUMAN, Q8NFP4 (See protein sequence)

Recommended Name: MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor

Size: 955 amino acids; 105790 Da

Subunit: Interacts heterophilically through its MAM domain with proteins in axon-rich regions and through its Ig-like

domains with proteins in differentiating muscle (By similarity)

Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor. Note=Associated with lipid rafts

Sequence caution: Sequence=BAC03502.1; Type=Erroneous initiation;

Secondary accessions: A6NHG0 Q8NBE3

Alternative splicing: 2 isoforms: Q8NFP4-1 Q8NFP4-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MDGA1: NX_Q8NFP4

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8NFP4

MDGA1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_705691.1

ENSEMBL proteins:

ENSP00000402584 ENSP00000422042 ENSP00000393330 ENSP00000425911 ENSP00000421510

ENSP00000427645 ENSP00000297153

Human Recombinant Protein Products:

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	Browse ProSpec Recombinant Proteins
	Uscn Proteins for MDGA1

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0046658	anchored to plasma membrane	ISS	15019943

MDGA1 for ontologies About GeneDecksing

MDGA1 Antibody Products:

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	Search ThermoFisher Antibodies for MDGA1

Assay Products for MDGA1:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for MDGA1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for MDGA1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

MDGA1 for domains About GeneDecksing

5/8 InterPro domains/families (see all 8):

IPR003598 Ig_sub2

IPR003961 Fibronectin_type3

IPR013098 Ig_I-set

IPR013783 Ig-like_fold

IPR007110 Ig-like_dom

Graphical View of Domain Structure for InterPro Entry Q8NFP4

ProtoNet protein and cluster: Q8NFP4

3 Blocks protein families:

IPB000998 MAM domain signature

IPB003598 Immunoglobulin C-2 type

IPB003599 Immunoglobulin subtype

UniProtKB/Swiss-Prot: MDGA1_HUMAN, Q8NFP4

Similarity: Contains 1 fibronectin type-III domain

Similarity: Contains 6 Ig-like (immunoglobulin-like) domains

Similarity: Contains 1 MAM domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: MDGA1_HUMAN, Q8NFP4

Function: Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity)

miRNA Products:		miRTarBase miRNAs that target MDGA1: hsa-mir-210 (MIRT003161)

		OriGene 3'-UTR Clone: MDGA1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MDGA1
		8/86 QIAGEN miScript miRNA Assays for microRNAs that regulate MDGA1 (see all 86):
		hsa-miR-3607-3p hsa-miR-200a hsa-miR-134 hsa-miR-128 hsa-miR-3138 hsa-miR-877* hsa-miR-629* hsa-miR-509-3-5p

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MDGA1 (see all 6) OriGene siRNA: MDGA1
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Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for MDGA1

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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for MDGA1
		Search LifeMap BioReagents cell lines for MDGA1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MDGA1

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--

MDGA1 for ontologies About GeneDecksing

Animal Models:
2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Mdga1):

cellular

nervous system

MDGA1 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MDGA1

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001764	neuron migration	ISS	--
GO:0007420	brain development	ISS	15019943
GO:0021527	spinal cord association neuron differentiation	ISS	15019943

MDGA1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MDGA1
Search CenterWatch for drugs/clinical trials and news about MDGA1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MDGA1 gene:

NM_153487.3

Unigene Cluster for MDGA1:

MAM domain containing glycosylphosphatidylinositol anchor 1

Hs.437993 [show with all ESTs]

Unigene Representative Sequence: AF478693

11 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000434837(uc003onu.1 uc003onv.1) ENST00000373401 ENST00000505425

ENST00000503419 ENST00000418178 ENST00000502298 ENST00000510077 ENST00000478143

ENST00000515437 ENST00000508399 ENST00000297153

miRNA Products:		OriGene 3'-UTR Clone: MDGA1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MDGA1
		8/86 QIAGEN miScript miRNA Assays for microRNAs that regulate MDGA1 (see all 86):
		hsa-miR-3607-3p hsa-miR-200a hsa-miR-134 hsa-miR-128 hsa-miR-3138 hsa-miR-877* hsa-miR-629* hsa-miR-509-3-5p

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MDGA1 (see all 6) OriGene siRNA: MDGA1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MDGA1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MDGA1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MDGA1 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: MDGA1 (NM_153487)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MDGA1
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Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MDGA1 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MDGA1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MDGA1

Additional cDNA sequence:

AF478693.1 AK055376.1 AK091650.1 AK092308.1 AK126965.1 BX647180.1 BX647253.1

7 DOTS entries:

DT.40113406 DT.101973692 DT.100022137 DT.100755333 DT.100022135 DT.204494 DT.40313562

24/81 AceView cDNA sequences (see all 81):

AA481631 AW014039 AF478693 BP344579 BX101256 NM_153487 AA325266 AK091149

AI813394 CK300811 AI827393 AW593235 R88808 AW003899 AX746808 AX746568

BF195188 BX647180 BU620610 BM673820 BE730067 AK055376 AI276717 AK126965

GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for MDGA1 (see all 12) About this scheme

ExUns:	1	^	2	^	3a	·	3b	^	4	^	5a	·	5b	^	6a	·	6b	^	7	^	8a	·	8b	^	9a	·	9b	^	10	^	11	^	12	^	13a	·	13b	·	13c	^	14a	·	14b	^	15	^	16	^	17	^	18a	·
SP1:
SP2:																																																	-		-
SP3:			-
SP4:
SP5:

ExUns:	18b	·	18c	^	19	^	20a	·	20b	·	20c
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for MDGA1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MDGA1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCTGACCACC

About this image

MDGA1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

6 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Spinal Cord

Spinal Dorsal Columns

Dorsal Spinal Cord Progenitor Cells

Spinal Cord

Spinal Ventral Columns

Ventral Spinal Cord Progenitor Cells

Motor Neurons

Brain

Neural Tube

Spinal Dorsal Columns

Spinal Cord

Spinal Ventral Columns

Spinal Cord

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See MDGA1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MDGA1

SOURCE GeneReport for Unigene cluster: Hs.437993

UniProtKB/Swiss-Prot: MDGA1_HUMAN, Q8NFP4

Tissue specificity: Has been found in brain, heart, skeletal muscle and kidney. Found to be overexpressed in tumor

tissues

SABiosciences Custom PCR Arrays for MDGA1

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MDGA1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MDGA1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for MDGA1 gene from 4/14 species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	MDGA1¹	MAM domain containing glycosylphosphatidylinositol more	74.64(n) 79.45(a)		421431 NM_001044647.1 NP_001038112.1
lizard (Anolis carolinensis)	Reptilia	MDGA1⁶	--	76(a)	possible ortholog	1(228758968-229100355)
African clawed frog (Xenopus laevis)	Amphibia	Xl.13549²	Xenopus laevis transcribed sequence with weak similarity more	72.51(n)		BJ057835.1
zebrafish (Danio rerio)	Actinopterygii	LOC569180¹	MAM domain-containing glycosylphosphatidylinositol more	65.54(n) 63.33(a)		569180 XM_692548.5 XP_697640.5

ENSEMBL Gene Tree for MDGA1 (if available)
TreeFam Gene Tree for MDGA1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for MDGA1 gene

MAMDC4² MDGA2² C10orf112² MAMDC2²

7 SIMAP similar genes for MDGA1 using alignment to 7 protein entries: MDGA1_HUMAN (see all proteins):

MDGA2 NRP1 L1CAM MUSK DCC NFASC

LSAMP

MDGA1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 6 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs193038534^1,2		--	37599786(+)	`TCCTTA/GAGCCT`	1	--	ds500¹		0	--	--	--	--
rs185780930^1,2		--	37599853(+)	`CTCTCC/TCAATC`	1	--	ds500¹		0	--	--	--	--
rs187220455^1,2		--	37599947(+)	`CCTCTC/TCATAC`	1	--	ds500¹		0	--	--	--	--
rs6926735^1,2	C,F,A,H,	--	37599962(+)	`TTTCAT/CAGCAC`	1	--	ds500¹		19		NS EA WA NA	2756
rs77311666^1,2	F,	--	37599985(+)	`CCAGCC/TCTCAC`	1	--	ds500¹		1		WA	118
rs111244846^1,2	C,	--	37599995(+)	`CTGTAC/TACATC`	1	--	ds500¹		1		NA	2
rs145593455^1,2	C,	--	37600107(+)	`AATGC-/ACGAGG ACACA`	1	--	ds500¹		0	--	--	--	--
rs61151079^1,2	C	--	37600109(+)	`TGCAC-/GAGGAC ACAAG`	1	--	ds500¹		0	--	--	--	--
rs6927074^1,2	C,F,A,H,	--	37600120(+)	`TTCACT/CGGGAG`	1	--	ds500¹		7		NS EA WA NA	778
rs75289615^1,2	F,	--	37600172(+)	`GGATCC/TCTGTC`	1	--	ds500¹		1		WA	118

HapMap Linkage Disequilibrium report for MDGA1 (37598455 - 37667082 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for MDGA1
2 CNVs: 69491 8512

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MDGA1

DNA2.0 Custom Variant and Variant Library Synthesis for MDGA1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

MDGA1 for disorders           About GeneDecksing

OMIM gene information: 609626    OMIM disorders: --

3 diseases for MDGA1:    About MalaCards

bipolar disorder schizophrenia neuronitis

Human Genome Epidemiology (HuGE) Navigator: MDGA1 (4 documents)

Export disorders for MDGA1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MDGA1 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with MDGA1)

Utopia: connect your pdf to the dynamic
world of online information

Characterization of MDGA1, a novel human glycosylphosphatidylinositol-anchored protein localized in lipid rafts. (PubMed id 15922729)^{1, 2, 3} Diaz-Lopez A....De Juan C. (2005)
Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)^{1, 2} Liu T.... Smith R.D. (2005)
Identification and characterization of two novel brain-derived immunoglobulin superfamily members with a unique structural organization. (PubMed id 15019943)^{1, 3} Litwack E.D....O'Leary D.D. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Genomic organization of a novel glycosylphosphatidylinositol MAM gene expressed in human tissues and tumors. (PubMed id 12082541)^{1, 2} De Juan C.... Benito M. (2002)
Proteomics strategy to identify substrates of LNX, a P DZ domain-containing E3 ubiquitin ligase. (PubMed id 22889411)¹ Guo Z....Gao Y. (2012)
The MDGA1 gene confers risk to schizophrenia and bipo lar disorder. (PubMed id 21146959)¹ Li J....Shi Y. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
WITHDRAWN: Common polymorphisms in the MDGA1 gene are associated with bipolar disorder and schizophrenia in the Chinese Han populati on. (PubMed id 20036297)¹ Li J....Shi Y. (2009)
Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene. (PubMed id 18384059)¹ Kahler A.K....Andreassen O.A. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 266727	HGNC: 19267	AceView: MDGA1	Ensembl:ENSG00000112139	euGenes: HUgn266727
ECgene: MDGA1	H-InvDB: MDGA1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for MDGA1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for MDGA1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for MDGA1 gene:
Search GeneIP for patents involving MDGA1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MDGA1

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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MDGA1 Gene

MAM domain containing glycosylphosphatidylinositol anchor...

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for MDGA1 gene

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for MDGA1 gene

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for MDGA1 gene

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for MDGA1 gene

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for MDGA1 gene

Genomic Variants
for MDGA1 gene

Disorders / Diseases
for MDGA1 gene

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for MDGA1 gene

Intellectual Property
for MDGA1 gene

Products
for MDGA1 gene