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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MDFI Gene

protein-coding   GIFtS: 54
GCID: GC06P041604

MyoD Family Inhibitor

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
MyoD Family Inhibitor1 2
Inhibitor Of MyoD Family A1 2
Myogenic Repressor I-Mf2 3
I-MF2
I-mfa2

External Ids:    HGNC: 69671   Entrez Gene: 41882   Ensembl: ENSG000001125597   OMIM: 6049715   UniProtKB: Q997503   

Export aliases for MDFI gene to outside databases

Previous GC identifers: GC06P041606 GC06P041653 GC06P041714 GC06P041324


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MDFI Gene:
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the
mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization
signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs
that also involve cartilage formation in these structures. (provided by RefSeq, Jul 2008)

GeneCards Summary for MDFI Gene: 
MDFI (MyoD family inhibitor) is a protein-coding gene. Diseases associated with MDFI include mycosis fungoides, and fanconi's anemia. GO annotations related to this gene include protein binding and transcription factor binding. An important paralog of this gene is MDFIC.

UniProtKB/Swiss-Prot: MDFI_HUMAN, Q99750
Function: Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis.
Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear
localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important
role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by
interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in
an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways (By
similarity)

Gene Wiki entry for MDFI Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_007592.15  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MDFI gene promoter:
         PPAR-gamma1   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): MDFI promoter sequence
   Search SABiosciences Chromatin IP Primers for MDFI

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MDFI


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21   Ensembl cytogenetic band:  6p21.1   HGNC cytogenetic band: 6p21

MDFI Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MDFI gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P041604:  view genomic region     (about GC identifiers)

Start:
41,604,620 bp from pter      End:
41,621,984 bp from pter
Size:
17,365 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MDFI_HUMAN, Q99750 (See protein sequence)
Recommended Name: MyoD family inhibitor  
Size: 246 amino acids; 25029 Da
Subunit: The C-terminus interacts with AXIN1 and LEF1 (By similarity)
Subcellular location: Nucleus (By similarity). Cytoplasm (By similarity)

Explore the universe of human proteins at neXtProt for MDFI: NX_Q99750

Explore proteomics data for MDFI at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q99750

  • MDFI Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MDFI Protein Expression
    REFSEQ proteins: NP_005577.1  
    ENSEMBL proteins: 
     ENSP00000413226   ENSP00000393881   ENSP00000362142   ENSP00000406600   ENSP00000230321  
     ENSP00000362141   ENSP00000411829   ENSP00000403587  

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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MDFI 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--
    GO:0005737cytoplasm IEA--

    MDFI for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR026134 MDFI/MDFIC

    Graphical View of Domain Structure for InterPro Entry Q99750

    ProtoNet protein and cluster: Q99750

    UniProtKB/Swiss-Prot: MDFI_HUMAN, Q99750
    Similarity: Belongs to the MDFI family


    MDFI for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MDFI_HUMAN, Q99750
    Function: Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis.
    Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear
    localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important
    role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by
    interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in
    an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways (By
    similarity)

         Genatlas biochemistry entry for MDFI:
    myogenic factor D family (MYOD) inhibitor homolog of mouse I-mfa,expressed in the sclerotome,involved in the
    patterning of somites

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16189514
    GO:0008134transcription factor binding IEA--
         
    MDFI for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for MDFI:
     Decreased number of cells in m 

         7 MGI mutant phenotypes (inferred from 1 allele(MGI details for Mdfi):
     embryogenesis  growth/size  limbs/digits/tail  mortality/aging  nervous system 
     respiratory system  skeleton 

    MDFI for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Mdfitm1Krt for MDFI

       inGenious Targeting Laboratory - Custom generated mouse model solutions for MDFI 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MDFI

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MDFI 
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    SwitchGear 3'UTR luciferase reporter plasmidMDFI 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MDFI

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/251 Interacting proteins for MDFI (Q997501, 2, 3 ENSP000002303214) via UniProtKB, MINT, STRING, and/or I2D (see all 251)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    C19orf60Q96EN91, 2, 3, ENSP000003514224EBI-724076,EBI-745810 MINT-66725 I2D: score=5 STRING: ENSP00000351422
    CNNM3Q8NE011, 2, 3, ENSP000003054494EBI-724076,EBI-741032 MINT-67938 I2D: score=5 STRING: ENSP00000305449
    FAM124BQ9H5Z61, 2, 3, ENSP000003868954EBI-724076,EBI-741626 MINT-66231 I2D: score=5 STRING: ENSP00000386895
    HOXB9P174821, 2, 3, ENSP000003094394EBI-724076,EBI-745290 MINT-67244 I2D: score=5 STRING: ENSP00000309439
    LASP1Q148471, 2, 3, ENSP000003252404EBI-724076,EBI-742828 MINT-67947 I2D: score=5 STRING: ENSP00000325240
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter ISS--
    GO:0007257activation of JUN kinase activity IEA--
    GO:0009790embryo development TAS8797820
    GO:0009950dorsal/ventral axis specification ISS--
    GO:0030111regulation of Wnt receptor signaling pathway ----

    MDFI for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MDFI

    Search CenterWatch for drugs/clinical trials and news about MDFI

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MDFI gene: 
    NM_005586.3  

    Unigene Cluster for MDFI:

    MyoD family inhibitor
    Hs.520119  [show with all ESTs]
    Unigene Representative Sequence: NM_005586
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000432027 ENST00000419164 ENST00000373051 ENST00000441667 ENST00000230321(uc003oqq.4 uc010jxn.3)
    ENST00000373050 ENST00000446650 ENST00000435476 ENST00000471092
    miRNA
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    8/23 QIAGEN miScript miRNA Assays for microRNAs that regulate MDFI (see all 23):
    hsa-let-7d hsa-miR-513a-5p hsa-miR-128 hsa-let-7c hsa-let-7g hsa-let-7a hsa-miR-23a hsa-miR-3909
    SwitchGear 3'UTR luciferase reporter plasmidMDFI 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: MDFI (NM_005586)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MDFI
    Sirion Biotech Customized lentivirus for stable overexpression of MDFI 
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MDFI

    Additional mRNA sequence: 

    BC007836.2 U78313.1 

    8 DOTS entries:

    DT.442453  DT.102827346  DT.102827347  DT.86852438  DT.91973964  DT.91814088  DT.92001583  DT.97812951 

    24/79 AceView cDNA sequences (see all 79):

    AI969786 AI291578 CR594049 BQ575606 BC007836 CR622975 CR610379 AI568654 
    AW628730 AI805342 AI805527 BI824391 BM662705 BQ679836 BF526462 BU164669 
    BF510961 BU190872 AI190979 CA487393 BF592879 BF344627 NM_005586 AI963860 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for MDFI (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b · 8c · 8d
    SP1:        -     -     -     -     -                                                         
    SP2:                    -     -     -                                                         
    SP3:                                                                                          
    SP4:                                                                                          
    SP5:                                            -                                             


    ECgene alternative splicing isoforms for MDFI

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MDFI expression in normal human tissues (normalized intensities)      MDFI embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCAGAGAAGC
    MDFI Expression
    About this image


    MDFI expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 3 entries
             Myoblasts Mandibular Arch Muscles
     
     Limb (Muscoskeletal System)
             Limb Muscle Progenitor Cells Forelimb Myotome
     
     Blood (Hematopoietic System)
             Hematopoietic Stem Cells Hematopoietic Bone Marrow

    See MDFI Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MDFI

    SOURCE GeneReport for Unigene cluster: Hs.520119
        SABiosciences Custom PCR Arrays for MDFI
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MDFI

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for MDFI gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mdfi1 , 5 MyoD family inhibitor1, 5 83.88(n)1
    79.92(a)1
      17 (23.99 cM)5
    172401  NM_001109973.11  NP_001103443.11 
     478153285 
    chicken
    (Gallus gallus)
    Aves LOC1008590311 myoD family inhibitor-like 74.41(n)
    68.69(a)
      100859031  XM_003642750.1  XP_003642798.1 
    lizard
    (Anolis carolinensis)
    Reptilia MDFI6
    Uncharacterized protein
    94(a)
    1 ↔ 1
    4(119766565-119766819)
    zebrafish
    (Danio rerio)
    Actinopterygii MDFI6
    zgc:1133636
    zgc:113363
    44(a)
    28(a)
    1 ↔ 1
    possible ortholog
    11(22944255-22997866)
    8(8276897-8290354)


    ENSEMBL Gene Tree for MDFI (if available)
    TreeFam Gene Tree for MDFI (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MDFI gene
    MDFIC2  
    1 SIMAP similar gene for MDFI using alignment to 7 protein entries:     MDFI_HUMAN (see all proteins):
    MDFIC

    MDFI for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/460 SNPs in MDFI are shown (see all 460)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs737359031,2
    C,F--41604209(+) TCCCAT/CGCCAG 1 -- us2k13Minor allele frequency- C:0.21WA CSA 121
    rs1905861891,2
    --41604272(+) TTAATA/GTGTTG 1 -- us2k10--------
    rs1412156841,2
    --41604274(+) AATGTA/GTTGAT 1 -- us2k10--------
    rs1500469821,2
    C--41604317(+) ATACAA/TACAAG 1 -- us2k10--------
    rs1930368701,2
    C--41604536(+) CTGGAC/TTGAGA 1 -- us2k10--------
    rs1453496881,2
    C--41604589(+) CGGGAA/GGGGGC 1 -- us2k10--------
    rs1853803111,2
    --41604605(+) ACGCGA/GGAGGA 1 -- us2k10--------
    rs1888912261,2
    --41604647(+) AGGTGA/GGTGAG 1 -- us2k10--------
    rs767411591,2
    F--41604722(+) CGTCCC/AGTCCG 1 -- us2k11Minor allele frequency- A:0.07WA 118
    rs1135774361,2
    F--41604795(+) GCCGGA/GTCCCG 1 -- us2k12Minor allele frequency- G:0.07CSA WA 120

    HapMap Linkage Disequilibrium report for MDFI (41604620 - 41621984 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for MDFI:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2657739CNV Deletion23128226
    esv2109973CNV Deletion18987734
    esv2731976CNV Deletion23290073
    nsv519925CNV Loss19592680
    nsv885830CNV Loss21882294
    dgv1943e1CNV Complex17122850
    dgv1944e1CNV Complex17122850
    dgv1945e1CNV Complex17122850

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604971    OMIM disorders: --

    4 diseases for MDFI:    About MalaCards
    mycosis fungoides    fanconi's anemia    choroiditis    anemia


    MDFI for disorders           About GeneDecksing

    Genetic Association Database (GAD): MDFI

    Export disorders for MDFI gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MDFI gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with MDFI)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The gene encoding I-mf (Mdfi) maps to human chromosome 6p21 and mouse chromosome 17. (PubMed id 9250874)1, 2, 3 Kraut N. (1997)
    2. Developmental regulators containing the I-mfa domain interact with T cyclins and Tat and modulate transcription. (PubMed id 17289077)1, 3, 9 Wang Q....Pe'ery T. (2007)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    5. Protein interactions of the transcription factor Hoxa1 . (PubMed id 23088713)1 Lambert B....Rezsohazy R. (2012)
    6. The global gene-expression profiles of U-937 human mac rophages treated with Tat peptide and Tat-FITC conjugate. (PubMed id 22632162)1 Lin C.W....Jan M.S. (2012)
    7. I-mfa domain proteins specifically interact with SERT A domain proteins and repress their transactivating functions. (PubMed id 21664411)1 Kusano S....Eizuru Y. (2011)
    8. Genetic determinants of cardiovascular events among w omen with migraine: a genome-wide association study. (PubMed id 21779381)4 SchA1rks M....Kurth T. (2011)
    9. Shifted Transversal Design smart-pooling for high cov erage interactome mapping. (PubMed id 19447967)1 Xin X....Thierry-Mieg N. (2009)
    10. TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells. (PubMed id 19850743)1 Vanderwerf S.M....Bagby G.C. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4188 HGNC: 6967 AceView: MDFI Ensembl:ENSG00000112559 euGenes: HUgn4188
    ECgene: MDFI H-InvDB: MDFI

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MDFI Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MDFI gene:
    Search GeneIP for patents involving MDFI

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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