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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MDFI Gene

protein-coding   GIFtS: 53
GCID: GC06P041604

MyoD family inhibitor
 Explore 5 diseases affiliated with
MDFI via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for MDFI    

Aliases
for MDFI gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
MyoD Family Inhibitor1 2
I-Mfa1
Myogenic Repressor I-Mf2 3
I-MF2
Inhibitor Of MyoD Family A2

External Ids:    HGNC: 69671   Entrez Gene: 41882   Ensembl: ENSG000001125597   OMIM: 6049715   UniProtKB: Q997503   

Export aliases for MDFI gene to outside databases

Previous GC identifers: GC06P041606 GC06P041653 GC06P041714 GC06P041324


Summaries
for MDFI gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for MDFI:
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse
homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and
preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve
cartilage formation in these structures. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: MDFI_HUMAN, Q99750
Function: Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts
by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization
signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in
trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting
directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in
the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways (By similarity)

Gene Wiki entry for MDFI


Genomic Views
for MDFI gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MDFI gene promoter:
         PPAR-gamma1   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): MDFI promoter sequence
   Search SABiosciences Chromatin IP Primers for MDFI

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MDFI


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21   Ensembl cytogenetic band:  6p21.1   HGNC cytogenetic band: 6p21

MDFI Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MDFI gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P041604:  view genomic region     (about GC identifiers)

Start:
 41,604,620 bp from pter      End:
 41,621,984 bp from pter
Size:
 17,365 bases      Orientation:
 plus strand

Proteins
for MDFI gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: MDFI_HUMAN, Q99750 (See protein sequence)
Recommended Name: MyoD family inhibitor  
Size: 246 amino acids; 25029 Da
Subunit: The C-terminus interacts with AXIN1 and LEF1 (By similarity)
Subcellular location: Nucleus (By similarity). Cytoplasm (By similarity)

Explore the universe of human proteins at neXtProt for MDFI: NX_Q99750

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q99750

    • MDFI Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_005577.1  
    ENSEMBL proteins: 
     ENSP00000413226   ENSP00000393881   ENSP00000362142   ENSP00000406600   ENSP00000230321  
     ENSP00000362141   ENSP00000411829   ENSP00000403587   ENSP00000446138  

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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for MDFI

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--
    GO:0005737cytoplasm IEA--


    MDFI for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for MDFI gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    MDFI for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR026134 MDFI/MDFIC

    Graphical View of Domain Structure for InterPro Entry Q99750

    ProtoNet protein and cluster: Q99750

    UniProtKB/Swiss-Prot: MDFI_HUMAN, Q99750
    Similarity: Belongs to the MDFI family


    Function
    for MDFI gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: MDFI_HUMAN, Q99750
    Function: Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts
    by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization
    signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in
    trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting
    directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in
    the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways (By similarity)

         Genatlas biochemistry entry for MDFI:
    myogenic factor D family (MYOD) inhibitor homolog of mouse I-mfa,expressed in the sclerotome,involved in the patterning
    of somites

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MDFI
    8/23 QIAGEN miScript miRNA Assays for microRNAs that regulate MDFI (see all 23):
    hsa-let-7d hsa-miR-513a-5p hsa-miR-128 hsa-let-7c hsa-let-7g hsa-let-7a hsa-miR-23a hsa-miR-3909
    SwitchGear 3'UTR luciferase reporter plasmid: MDFI 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MDFI (see all 7)
    OriGene shRNA RFP: MDFI
    OriGene siRNA: MDFI
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MDFI

    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0008134transcription factor binding IEA--


    MDFI for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for MDFI:
     Decreased number of cells in m 

    Animal Models:
         Mouse knock-out Mdfitm1Krt for MDFI
         7 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Mdfi):
     embryogenesis  growth/size  limbs/digits/tail  mortality/aging  nervous system 
     respiratory system  skeleton 

    MDFI for phenotypes           About GeneDecksing


    Pathways & Interactions
    for MDFI gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MDFI

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/242 Interacting proteins for MDFI (Q997501, 2, 3 ENSP000002303214) via UniProtKB, MINT, STRING, and/or I2D (see all 242)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CNNM3Q8NE011, 2, 3, ENSP000003054494EBI-724076,EBI-741032 MINT-67938 I2D: score=5 STRING: ENSP00000305449
    FAM124BQ9H5Z61, 2, 3, ENSP000003868954EBI-724076,EBI-741626 MINT-66231 I2D: score=5 STRING: ENSP00000386895
    HOXB9P174821, 2, 3, ENSP000003094394EBI-724076,EBI-745290 MINT-67244 I2D: score=5 STRING: ENSP00000309439
    LASP1Q148471, 2, 3, ENSP000003252404EBI-724076,EBI-742828 MINT-67947 I2D: score=5 STRING: ENSP00000325240
    NR1H2P550551, 2, 3, ENSP000002537274EBI-724076,EBI-745354 MINT-66648 I2D: score=5 STRING: ENSP00000253727
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter ISS--
    GO:0007257activation of JUN kinase activity IEA--
    GO:0009790embryo development TAS8797820
    GO:0009950dorsal/ventral axis specification ISS--
    GO:0030111regulation of Wnt receptor signaling pathway ----


    MDFI for ontologies           About GeneDecksing



    Drugs & Compounds
    for MDFI gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MDFI
    Search CenterWatch for drugs/clinical trials and news about MDFI 

    Transcripts
    for MDFI gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for MDFI gene: 
    NM_005586.3  

    Unigene Cluster for MDFI:

    MyoD family inhibitor
    Hs.520119  [show with all ESTs]
    Unigene Representative Sequence: NM_005586
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000432027 ENST00000419164 ENST00000373051 ENST00000441667 ENST00000230321(uc003oqq.4 uc010jxn.3)
    ENST00000373050 ENST00000446650 ENST00000435476 ENST00000471092 ENST00000543326


    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MDFI
    8/23 QIAGEN miScript miRNA Assays for microRNAs that regulate MDFI (see all 23):
    hsa-let-7d hsa-miR-513a-5p hsa-miR-128 hsa-let-7c hsa-let-7g hsa-let-7a hsa-miR-23a hsa-miR-3909
    SwitchGear 3'UTR luciferase reporter plasmid: MDFI 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MDFI (see all 7)
    OriGene shRNA RFP: MDFI
    OriGene siRNA: MDFI
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MDFI
    Clone
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: MDFI (NM_005586)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MDFI 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MDFI
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MDFI

    Additional cDNA sequence: 

    BC007836.2 U78313.1 

    8 DOTS entries:

    DT.442453  DT.102827346  DT.102827347  DT.86852438  DT.91973964  DT.91814088  DT.92001583  DT.97812951 

    24/79 AceView cDNA sequences (see all 79):

    BQ679836 AI805527 CR622975 BQ575606 AI291578 BI824391 BM662705 CR594049 
    AW628730 CR610379 BC007836 AI969786 AI568654 AI805342 BU164669 BX397111 
    BF204500 BF592879 BG818571 AI692917 CF541234 AI190979 CA487393 NM_005586 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for MDFI (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b · 8c · 8d
    SP1:        -     -     -     -     -                                                         
    SP2:                    -     -     -                                                         
    SP3:                                                                                          
    SP4:                                                                                          
    SP5:                                            -                                             


    ECgene alternative splicing isoforms for MDFI

    Expression
    for MDFI gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MDFI expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCAGAGAAGC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    MDFI expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    LimbForelimb MyotomeLimb Muscle Progenitor CellsSkeletal Muscle
    TestisSeminiferous TubulesSertoli cellsTestis
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See MDFI Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MDFI

    SOURCE GeneReport for Unigene cluster: Hs.520119
        SABiosciences Custom PCR Arrays for MDFI
    Primer
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    In Situ
    Assay Products:     
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    Orthologs
    for MDFI gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for MDFI gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Mdfi1 , 5 MyoD family inhibitor1, 5 83.88(n)1
    79.92(a)1    		   17 (23.99 cM)5
    172401  NM_001109973.11  NP_001103443.11 
     478153285 
    chicken
    (Gallus gallus)    		 Aves LOC1008590311 myoD family inhibitor-like 74.41(n)
    68.69(a)    		   100859031  XM_003642750.1  XP_003642798.1 
    lizard
    (Anolis carolinensis)    		 Reptilia MDFI6
    		 --
    		 95(a)
    		 1 ↔ 1
    		 4(119766565-119766819)
    zebrafish
    (Danio rerio)    		 Actinopterygii CR853302.16
    zgc:1133636
    		 zgc:113363
    		 46(a)
    25(a)
    		 1 ↔ 1
    possible ortholog
    		 11(22944255-22997866)
    8(8276897-8290354)


    ENSEMBL Gene Tree for MDFI (if available)
    TreeFam Gene Tree for MDFI (if available) 

    Paralogs
    for MDFI gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MDFI gene
    MDFIC2  
    1 SIMAP similar gene for MDFI using alignment to 7 protein entries:     MDFI_HUMAN (see all proteins):
    MDFIC

    MDFI for paralogs           About GeneDecksing



    Genomic Variants
    for MDFI gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/377 NCBI SNPs in MDFI are shown (see all 377)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs737359031,2
    		C,--41604209(+) TCCCAT/CGCCAG 1 -- us2k13Minor allele frequency- C:0.21WA CSA 121
    rs1905861891,2
    		--41604272(+) TTAATA/GTGTTG 1 -- us2k10--------
    rs1412156841,2
    		--41604274(+) AATGTA/GTTGAT 1 -- us2k10--------
    rs1500469821,2
    		--41604317(+) ATACAA/TACAAG 1 -- us2k10--------
    rs1930368701,2
    		--41604536(+) CTGGAC/TTGAGA 1 -- us2k10--------
    rs1453496881,2
    		--41604589(+) CGGGAA/GGGGGC 1 -- us2k10--------
    rs1853803111,2
    		--41604605(+) ACGCGA/GGAGGA 1 -- us2k10--------
    rs1888912261,2
    		--41604647(+) AGGTGA/GGTGAG 1 -- us2k10--------
    rs767411591,2
    		F,--41604722(+) CGTCCC/AGTCCG 1 -- us2k11Minor allele frequency- A:0.07WA 118
    rs1135774361,2
    		--41604795(+) GCCGGA/GTCCCG 1 -- us2k12Minor allele frequency- G:0.07CSA WA 120

    HapMap Linkage Disequilibrium report for MDFI (41604620 - 41621984 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for MDFI
         2 CNVs: 2626 3609

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MDFI
    DNA2.0 Custom Variant and Variant Library Synthesis for MDFI

    Disorders / Diseases
    for MDFI gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    MDFI for disorders           About GeneDecksing

    OMIM gene information: 604971    OMIM disorders: --

    5 diseases for MDFI:    About MalaCards
    mycosis fungoides    fanconi's anemia    anemia    choroiditis
    ataxia


    Export disorders for MDFI gene to outside databases

    Publications
    for MDFI gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MDFI gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with MDFI)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The gene encoding I-mf (Mdfi) maps to human chromosome 6p21 and mouse chromosome 17. (PubMed id 9250874)1, 2, 3 Kraut N. (1997)
    2. Developmental regulators containing the I-mfa domain interact with T cyclins and Tat and modulate transcription. (PubMed id 17289077)1, 3, 9 Wang Q....Pe'ery T. (2007)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    5. The global gene-expression profiles of U-937 human mac rophages treated with Tat peptide and Tat-FITC conjugate. (PubMed id 22632162)1 Lin C.W....Jan M.S. (2012)
    6. I-mfa domain proteins specifically interact with SERT A domain proteins and repress their transactivating functions. (PubMed id 21664411)1 Kusano S....Eizuru Y. (2011)
    7. Shifted Transversal Design smart-pooling for high cov erage interactome mapping. (PubMed id 19447967)1 Xin X....Thierry-Mieg N. (2009)
    8. TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells. (PubMed id 19850743)1 Vanderwerf S.M....Bagby G.C. (2009)
    9. An empirical framework for binary interactome mapping . (PubMed id 19060904)1 Venkatesan K....Vidal M. (2009)
    10. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (2006)

    External Searches for MDFI gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing MDFI gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4188 HGNC: 6967 AceView: MDFI Ensembl:ENSG00000112559 euGenes: HUgn4188
    ECgene: MDFI H-InvDB: MDFI

    Other Databases showing MDFI gene

    (According to HUGE)
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    		   --

    Specialized Databases showing MDFI gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MDFI Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for MDFI gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for MDFI gene:
    Search GeneIP for patents involving MDFI

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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