Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



MCUR1 Gene

protein-coding   GIFtS: 40
GCID: GC06M013788

Mitochondrial Calcium Uniporter Regulator 1

(Previous names: chromosome 6 open reading frame 79, coiled-coil domain containing...)
(Previous symbols: C6orf79, CCDC90A)
  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Mitochondrial Calcium Uniporter Regulator 11 2
C6orf791 2 3
CCDC90A1 2 3
Coiled-Coil Domain Containing 90A1 2
Coiled-Coil Domain-Containing Protein 90A, Mitochondrial2 3
Chromosome 6 Open Reading Frame 791

External Ids:    HGNC: 210971   Entrez Gene: 639332   Ensembl: ENSG000000503937   UniProtKB: Q96AQ83   
ORGUL members:         

Export aliases for MCUR1 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for MCUR1 Gene:
MCUR1 (mitochondrial calcium uniporter regulator 1) is a protein-coding gene. An important paralog of this gene is CCDC90B.

UniProtKB/Swiss-Prot: MCUR1_HUMAN, Q96AQ8
Function: Key regulator of mitochondrial calcium uniporter (MCU) required for calcium entry into mitochondrion.
Plays a direct role in uniporter-mediated calcium uptake, possibly via a direct interaction with MCU




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_007592.16  NC_018917.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for MCUR1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMCUR1 promoter sequence
   Search Chromatin IP Primers for MCUR1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MCUR1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p23   Ensembl cytogenetic band:  6p23   HGNC cytogenetic band: 6p23

MCUR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MCUR1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M013788:  view genomic region     (about GC identifiers)

Start:
13,786,781 bp from pter      End:
13,814,800 bp from pter
Size:
28,020 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: MCUR1_HUMAN, Q96AQ8 (See protein sequence)
Recommended Name: Mitochondrial calcium uniporter regulator 1  
Size: 359 amino acids; 39694 Da
Subunit: Interacts with MCU
Secondary accessions: Q96JS7 Q9H7F8
Alternative splicing: 2 isoforms:  Q96AQ8-1   Q96AQ8-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MCUR1: NX_Q96AQ8

Explore proteomics data for MCUR1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See MCUR1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001026883.1  
    ENSEMBL proteins: 
     ENSP00000368468   ENSP00000476106   ENSP00000476162   ENSP00000352475  

    MCUR1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for MCUR1
    OriGene Custom MassSpec
    OriGene Custom Protein Services for MCUR1
    GenScript Custom Purified and Recombinant Proteins Services for MCUR1
    Novus Biologicals MCUR1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for MCUR1 

     
    Search antibodies-online for proteins for MCUR1 

     
    antibodies-online peptides for MCUR1

    MCUR1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for MCUR1
    Novus Biologicals MCUR1 Antibodies
    Search for Antibodies for MCUR1 at Abcam
    Browse Antibodies at Cloud-Clone Corp.
    Search ThermoFisher Antibodies for MCUR1
    antibodies-online antibodies for MCUR1 (2 products) 

    MCUR1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for MCUR1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MCUR1
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for MCUR1 
    antibodies-online kits for MCUR1 (14 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR024461 DUF1640

    Graphical View of Domain Structure for InterPro Entry Q96AQ8

    ProtoNet protein and cluster: Q96AQ8

    1 Blocks protein domain: IPB012439 Protein of unknown function DUF1640

    UniProtKB/Swiss-Prot: MCUR1_HUMAN, Q96AQ8
    Similarity: Belongs to the CCDC90 family


    Find genes that share domains with MCUR1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MCUR1_HUMAN, Q96AQ8
    Function: Key regulator of mitochondrial calcium uniporter (MCU) required for calcium entry into mitochondrion.
    Plays a direct role in uniporter-mediated calcium uptake, possibly via a direct interaction with MCU

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with MCUR1           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for MCUR1

    miRNA
    Products:
        
    miRTarBase miRNAs that target MCUR1:
    hsa-mir-26b-5p (MIRT029243), hsa-mir-484 (MIRT041904)

    Block miRNA regulation of human, mouse, rat MCUR1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate MCUR1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for MCUR1
    Predesigned siRNA for gene silencing in human, mouse, rat MCUR1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for MCUR1

    Clone
    Products:
         
    OriGene clones in human, mouse for MCUR1 (see all 6)
    OriGene ORF clones in mouse, rat for MCUR1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for MCUR1
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MCUR1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MCUR1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for MCUR1
    Browse ESI BIO Cell Lines and PureStem Progenitors for MCUR1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MCUR1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    MCUR1_HUMAN, Q96AQ8: Mitochondrion inner membrane; Multi-pass membrane protein

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0031305integral component of mitochondrial inner membrane IDA--

    Find genes that share ontologies with MCUR1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MCUR1
    Interactions:

        Search GeneGlobe Interaction Network for MCUR1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for MCUR1 (ENSP000003684684) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SURF4ENSP000003610574STRING: ENSP00000361057
    GRWD1ENSP000002532374STRING: ENSP00000253237
    ZC3H14ENSP000002510384STRING: ENSP00000251038
    LETM1ENSP000003056534STRING: ENSP00000305653
    LETM2ENSP000002977204STRING: ENSP00000297720
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006851mitochondrial calcium ion transport IMP--
    GO:0051561positive regulation of mitochondrial calcium ion concentration IMP--
    GO:0070509calcium ion import IMP--

    Find genes that share ontologies with MCUR1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MCUR1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for MCUR1 gene (2 alternative transcripts): 
    NM_022102.1  NM_001031713.3  

    Unigene Cluster for MCUR1:

    Mitochondrial calcium uniporter regulator 1
    Hs.214043  [show with all ESTs]
    Unigene Representative Sequence: NM_001031713
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000379170(uc003nbc.2) ENST00000607303 ENST00000488770(uc010jpf.3)
    ENST00000359495
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MCUR1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate MCUR1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MCUR1
    Predesigned siRNA for gene silencing in human, mouse, rat MCUR1
    Clone
    Products:
         
    OriGene clones in human, mouse for MCUR1 (see all 6)
    OriGene ORF clones in mouse, rat for MCUR1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for MCUR1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MCUR1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MCUR1
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for MCUR1
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat MCUR1
      QuantiTect SYBR Green Assays in human, mouse, rat MCUR1
      QuantiFast Probe-based Assays in human, mouse, rat MCUR1

    Additional mRNA sequence: 

    AK026843.1 AK123750.1 BC008234.1 BC016850.1 BX640678.1 

    8 DOTS entries:

    DT.410790  DT.87015772  DT.100763196  DT.95147975  DT.100707247  DT.95374349  DT.99998593  DT.97848030 

    Selected AceView cDNA sequences (see all 111):

    W39762 BG674768 BG163607 BC016850 BE217798 BU620569 AA825405 CK825518 
    AI985420 BQ440064 BX280693 BM678103 BQ433879 BQ639591 BM471849 BE466132 
    BM847299 CA310091 BQ271177 BQ945087 W45285 BE218279 BQ948311 BQ286356 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for MCUR1    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10
    SP1:        -                                                         
    SP2:                                                                  


    ECgene alternative splicing isoforms for MCUR1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    MCUR1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    MCUR1 Expression
    About this image

    MCUR1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MCUR1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.214043

    UniProtKB/Swiss-Prot: MCUR1_HUMAN, Q96AQ8
    Tissue specificity: Ubiquitously expressed

        Custom PCR Arrays for MCUR1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for MCUR1
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat MCUR1
    QuantiTect SYBR Green Assays in human, mouse, rat MCUR1
    QuantiFast Probe-based Assays in human, mouse, rat MCUR1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MCUR1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for MCUR1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ccdc90a5
    Mcur11
    coiled-coil domain containing 90A5
    mitochondrial calcium uniporter regulator 11
    77.11(n)1
    75.9(a)1
      13 (21.60 cM)5
    761371  NM_001081059.31  NP_001074528.11 
     435384125 
    chicken
    (Gallus gallus)
    Aves CCDC90A1 coiled-coil domain containing 90A 68.35(n)
    67.44(a)
      420837  XM_418928.4  XP_418928.1 
    lizard
    (Anolis carolinensis)
    Reptilia MCUR16
    mitochondrial calcium uniporter regulator 1
    60(a)
    1 ↔ 1
    4(57161976-57179361)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.193152 Xenopus laevis transcribed sequence with weak similarity more 76(n)    CA792747.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb37a052 Transcribed sequence with weak similarity to protein more 75.51(n)    57037484 


    ENSEMBL Gene Tree for MCUR1 (if available)
    TreeFam Gene Tree for MCUR1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for MCUR1 gene
    CCDC90B2  
    1 SIMAP similar gene for MCUR1 using alignment to 2 protein entries:     MCUR1_HUMAN (see all proteins):
    CCDC90B

    Find genes that share paralogs with MCUR1           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for MCUR1
    PGOHUM00000236900 PGOHUM00000237852


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for MCUR1 (see all 658)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs18833411,2
    C,F,A--13786316(+) aaccgC/Tgcccg 1 -- int112Minor allele frequency- T:0.25NA WA CSA EA 374
    rs1810682411,2
    --13786321(+) TGCCCC/GGCCAG 1 -- int10--------
    rs1852262821,2
    --13786451(+) CAACAC/TAGTGA 1 -- int10--------
    rs1461100141,2
    --13786669(+) ATTGTC/GTATTT 1 -- int10--------
    rs1903779891,2
    --13787009(+) ATAATA/GAAACA 1 -- ut310--------
    rs10530331,2
    C,F,O,A,H--13787084(-) CACATC/G/TTTACA 2 -- ut318MN NS EA WA NA 842
    rs38005041,2
    C--13787098(+) AAAGAC/TAAATA 1 -- ut310--------
    rs1825453561,2
    --13787173(+) AATTAC/TTTCTG 1 -- ut310--------
    rs38005051,2
    C,F--13787304(+) CAAAAT/CTCTTA 1 -- ut316Minor allele frequency- C:0.17WA NA EA 364
    rs38005061,2
    C,F,A,H--13787316(+) AAGATC/TGCATG 1 -- ut3128Minor allele frequency- T:0.26NS EA NA WA CSA 2269

    HapMap Linkage Disequilibrium report for MCUR1 (13786781 - 13814800 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for MCUR1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MCUR1
    DNA2.0 Custom Variant and Variant Library Synthesis for MCUR1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for MCUR1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with MCUR1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. MCUR1 is an essential component of mitochondrial Ca(2+) uptake that regulates cellular metabolism. (PubMed id 23178883)1, 2, 3 Mallilankaraman K.... Madesh M. (Nat. Cell Biol. 2012)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    5. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (Genome Res. 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)2 Mungall A.J.... Beck S. (Nature 2003)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 63933 HGNC: 21097 AceView: C6orf79 Ensembl:ENSG00000050393 euGenes: HUgn63933
    ECgene: MCUR1 H-InvDB: MCUR1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for MCUR1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for MCUR1 gene:
    Search GeneIP for patents involving MCUR1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for MCUR1  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for MCUR1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for MCUR1  
     OriGene qSTAR qPCR primer pairs in human, mouse for MCUR1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for MCUR1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for MCUR1   OriGene Custom Protein Services for MCUR1  

     
     
     Block miRNA regulation of human, mouse, rat MCUR1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing MCUR1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MCUR1 Predesigned siRNA for gene silencing in human, mouse, rat MCUR1
     QuantiFast Probe-based Assays in human, mouse, rat MCUR1 QuantiTect SYBR Green Assays in human, mouse, rat MCUR1
     Custom PCR Arrays for MCUR1 Search Chromatin IP Primers for MCUR1
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat MCUR1 Search GeneGlobe Interaction Network for MCUR1
     Search Regulatory tfbs for MCUR1
     GenScript Custom Purified and Recombinant Proteins Services for MCUR1 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for MCUR1
     GenScript Custom Assay Services for MCUR1 GenScript Custom overexpressing Cell Line Services for MCUR1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for MCUR1
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     MCUR1 antibodies
     MCUR1 lysates
     Search for Antibodies for MCUR1 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for MCUR1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for MCUR1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MCUR1
     Browse SwitchGear 3'UTR luciferase reporter plasmids for MCUR1
     SwitchGear Promoter luciferase reporter plasmids for MCUR1
     Search ThermoFisher Antibodies for MCUR1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MCUR1
     Browse compounds at ApexBio
     Search Addgene for plasmids for MCUR1
      Search eBioscience for proteins for MCUR1
      Search eBioscience for elisas for MCUR1
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for MCUR1
     antibodies-online antibodies for MCUR1 (2 products)
     antibodies-online kits for MCUR1 (14 products)
     antibodies-online peptides for MCUR1
      Search antibodies-online for proteins for MCUR1
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      MCUR1 gene at Home site.
    Version: 3.12.258 10 Dec 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4