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MCTP2 Gene

protein-coding   GIFtS: 53
GCID: GC15P094774

Multiple C2 Domains, Transmembrane 2

  See MCTP2-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Multiple C2 Domains, Transmembrane 21 2
Multiple C2 And Transmembrane Domain-Containing Protein 22
Multiple C2-Domains With Two Transmembrane Regions 2 12

External Ids:    HGNC: 256361   Entrez Gene: 557842   Ensembl: ENSG000001405637   UniProtKB: Q6DN123   

Export aliases for MCTP2 gene to outside databases

Previous GC identifers: GC15P092575 GC15P092642 GC15P070976


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MCTP2 Gene:
MCTP2 (multiple C2 domains, transmembrane 2) is a protein-coding gene. Diseases associated with MCTP2 include distal monosomy 15q, and drug-induced liver injury due to flucloxacillin. GO annotations related to this gene include calcium-dependent phospholipid binding and calcium ion binding. An important paralog of this gene is ESYT1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000015.9  NT_010194.18  NC_018926.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MCTP2 gene promoter:
         HFH-3   Tal-1   STAT5A   E47   FOXI1   CREB   RORalpha1   POU2F1   deltaCREB   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMCTP2 promoter sequence
   Search Chromatin IP Primers for MCTP2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MCTP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q26.2   Ensembl cytogenetic band:  15q26.2   HGNC cytogenetic band: 15q26.2

MCTP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MCTP2 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P094774:  view genomic region     (about GC identifiers)

Start:
94,774,767 bp from pter      End:
95,027,181 bp from pter
Size:
252,415 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MCTP2_HUMAN, Q6DN12 (See protein sequence)
Recommended Name: Multiple C2 and transmembrane domain-containing protein 2  
Size: 878 amino acids; 99596 Da
Cofactor: Binds calcium via the C2 domains in absence of phospholipids
Sequence caution: Sequence=AAH41387.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=BAA91998.1;
Type=Erroneous initiation; Note=Translation N-terminally extended;
1 PDB 3D structure from and Proteopedia for MCTP2:
2EP6 (3D)    
Secondary accessions: A2RRC2 C6G483 C6G484 Q49AB0 Q8TAX2 Q9NUS2 Q9NUW7
Alternative splicing: 5 isoforms:  Q6DN12-1   Q6DN12-2   Q6DN12-3   Q6DN12-4   Q6DN12-6   (No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for MCTP2: NX_Q6DN12

Explore proteomics data for MCTP2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See MCTP2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001153115.1  NP_001153116.1  NP_060819.3  

    ENSEMBL proteins: 
     ENSP00000438521   ENSP00000388887   ENSP00000395109   ENSP00000350377   ENSP00000454847  
     ENSP00000329646  

    MCTP2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR013583 PRibTrfase_C
     IPR000008 C2_dom

    Graphical View of Domain Structure for InterPro Entry Q6DN12

    ProtoNet protein and cluster: Q6DN12

    1 Blocks protein domain: IPB000008 C2 domain

    UniProtKB/Swiss-Prot: MCTP2_HUMAN, Q6DN12
    Similarity: Belongs to the MCTP family
    Similarity: Contains 3 C2 domains


    Find genes that share domains with MCTP2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IDA15528213
    GO:0005515protein binding ----
    GO:0005544NOT calcium-dependent phospholipid binding IDA15528213
         
    Find genes that share ontologies with MCTP2           About GenesLikeMe


    Animal Models:
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    miRNA
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    miRTarBase miRNAs that target MCTP2:
    hsa-mir-26b-5p (MIRT029558)

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    hsa-miR-579 hsa-miR-548j hsa-miR-582-3p hsa-miR-607 hsa-miR-3194-5p hsa-miR-218-1* hsa-miR-374a hsa-miR-342-3p
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MCTP2_HUMAN, Q6DN12: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus2
    plasma membrane2
    cytosol1
    endoplasmic reticulum1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IDA15528213

    Find genes that share ontologies with MCTP2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MCTP2
    Interactions:

        Search GeneGlobe Interaction Network for MCTP2

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for MCTP2 (Q6DN123 ENSP000003503774) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    METTL9ENSP000003508744STRING: ENSP00000350874
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0019722calcium-mediated signaling NAS15528213

    Find genes that share ontologies with MCTP2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MCTP2

    1 HMDB Compound for MCTP2    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MCTP2 gene (3 alternative transcripts): 
    NM_001159643.1  NM_001159644.1  NM_018349.3  

    Unigene Cluster for MCTP2:

    Multiple C2 domains, transmembrane 2
    Hs.33368  [show with all ESTs]
    Unigene Representative Sequence: NM_018349
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000543482(uc010urg.1) ENST00000561608 ENST00000556363(uc002btg.4 uc002bth.4)
    ENST00000456504(uc010boj.3 uc002btj.3 uc010bok.3 uc002btl.3)
    ENST00000451018 ENST00000357742 ENST00000557742(uc002btk.4) ENST00000557505
    ENST00000449432 ENST00000331706(uc002bti.2)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate MCTP2 (see all 98):
    hsa-miR-579 hsa-miR-548j hsa-miR-582-3p hsa-miR-607 hsa-miR-3194-5p hsa-miR-218-1* hsa-miR-374a hsa-miR-342-3p
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      QuantiTect SYBR Green Assays in human, mouse, rat MCTP2
      QuantiFast Probe-based Assays in human, mouse, rat MCTP2

    Additional mRNA sequence: 

    AK001953.1 AK002037.1 AK026984.1 AK090622.1 AK300325.1 AL360258.1 AL832048.1 AL832717.1 
    AY656717.1 BC025708.1 BC041387.1 BC111024.1 BC131527.1 

    11 DOTS entries:

    DT.95158352  DT.95158351  DT.97785146  DT.410812  DT.75164910  DT.100016136  DT.210483  DT.99933072 
    DT.100777969  DT.121054434  DT.40111500 

    Selected AceView cDNA sequences (see all 83):

    AA451742 BU073254 BC025708 CB131405 AK002037 AI742835 AA279534 AA748418 
    AX746539 AL360258 BX485665 AA554052 AA309413 AA564430 AK090622 AI093216 
    AK001953 AA827812 BM661960 AA477006 CA430843 AA280207 BQ013742 BE677929 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MCTP2 (see all 8)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b · 12c ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^ 19a · 19b ^ 20 ^
    SP1:              -                                               -           -                                                     -           -               
    SP2:                                                                                            -                                   -           -               
    SP3:        -     -                 -                             -           -                                                                                 
    SP4:                                                                                            -                                   -           -               
    SP5:        -                       -                                                                                                                           

    ExUns: 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28a · 28b · 28c
    SP1:  -                             -                           
    SP2:  -                             -                           
    SP3:                                                            
    SP4:                                                            
    SP5:                                                            


    ECgene alternative splicing isoforms for MCTP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MCTP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAAAATCCT
    MCTP2 Expression
    About this image

    MCTP2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MCTP2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.33368
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MCTP2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MCTP2 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mctp21 , 5 multiple C2 domains, transmembrane 21, 5 85.88(n)1
    89.29(a)1
      7 (41.23 cM)5
    2440491  NM_001024703.11  NP_001019874.11 
     720778325 
    chicken
    (Gallus gallus)
    Aves LOC4263241 multiple C2 and transmembrane domain-containing protein more 72.44(n)
    71.27(a)
      426324  XM_004943863.1  XP_004943920.1 
    lizard
    (Anolis carolinensis)
    Reptilia MCTP26
    multiple C2 domains, transmembrane 2
    68(a)
    1 ↔ 1
    GL343351.1(42092-152595)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia mctp21 multiple C2 domains, transmembrane 2 66.82(n)
    65.06(a)
      100498038  XM_002933311.2  XP_002933357.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mctp2a1 multiple C2 domains, transmembrane 2a 58.86(n)
    52.86(a)
      562393  XM_685778.6  XP_690870.6 
    fruit fly
    (Drosophila melanogaster)
    Insecta Mctp6
    Multiple C2 domain and transmembrane region protei...
    32(a)
    1 → many
    2R(14649263-14662172)
    worm
    (Caenorhabditis elegans)
    Secernentea D2092.16
    Protein D2092.1, isoform b
    32(a)
    1 → many
    I(6629759-6637429) WBGene00017063
    rice
    (Oryza sativa)
    Liliopsida Os04g06918001 Os04g0691800 37.31(n)
    25.04(a)
      4337508  NM_001060897.2  NP_001054362.1 


    ENSEMBL Gene Tree for MCTP2 (if available)
    TreeFam Gene Tree for MCTP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MCTP2 gene
    ESYT12  ESYT32  MCTP12  ESYT22  
    2 SIMAP similar genes for MCTP2 using alignment to 2 protein entries:     MCTP2_HUMAN (see all proteins):
    MCTP1    PRKCG

    Find genes that share paralogs with MCTP2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MCTP2 (see all 4552)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs345136731,2
    C--71104887(+) AGATT-/GAGA  
            
    GAGAG
    2 -- int10--------
    rs1501215351,2
    C--74673976(+) TTGTG-/CACACA
            
    CACAC
    2 -- int10--------
    rs1125725231,2
    C--74720790(+) TGTGG-/A/AA  
            
    AAAAA
    2 -- int11CSA 2
    rs71758711,2
    H--94839477(+) TATGAG/AATGTG 2 -- us2k14Minor allele frequency- A:0.00NS EA 418
    rs1884262291,2
    --94839499(+) CTTGCA/GTATTG 2 -- us2k10--------
    rs13785971,2
    C,F,A,H--94839569(-) AAATAG/TTTTAC 2 -- us2k18Minor allele frequency- T:0.32NA WA EA 370
    rs1148651481,2
    C,F--94839591(+) AGCCAA/GAATGA 2 -- us2k11Minor allele frequency- G:0.05WA 118
    rs1135606201,2
    C--94839655(+) ATTTAC/TTCCAT 2 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs1476244611,2
    C--94839747(+) TGTTAA/GACTCA 2 -- us2k10--------
    rs740309291,2
    C,F--94839773(+) TAACAG/ATGAGA 2 -- us2k13Minor allele frequency- A:0.08WA NA 240

    HapMap Linkage Disequilibrium report for MCTP2 (94774767 - 95024767 bp, first 250kb of MCTP2)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for MCTP2 (see all 17):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1647697CNV Deletion17803354
    esv2750070CNV Deletion23290073
    esv1007834CNV Deletion20482838
    esv2750071CNV Deletion23290073
    nsv820715CNV Duplication20802225
    nsv513437CNV Insertion21212237
    esv2474634CNV Insertion19546169
    nsv904522CNV Loss21882294
    nsv520668CNV Loss19592680
    esv22514CNV Loss19812545

    Human Gene Mutation Database (HGMD): MCTP2
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MCTP2
    DNA2.0 Custom Variant and Variant Library Synthesis for MCTP2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for MCTP2:    
    About MalaCards
    distal monosomy 15q    drug-induced liver injury due to flucloxacillin


    Find genes that share disorders with MCTP2           About GenesLikeMe

    Genetic Association Database (GAD): MCTP2
    Human Genome Epidemiology (HuGE) Navigator: MCTP2 (4 documents)

    Export disorders for MCTP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MCTP2 gene, integrated from 10 sources (see all 31):
    (articles sorted by number of sources associating them with MCTP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Evolutionarily conserved multiple C2 domain proteins with two transmembrane regions (MCTPs) and unusual Ca2+ binding properties. (PubMed id 15528213)1, 2, 3 Shin O.H.... Sudhof T.C. (J. Biol. Chem. 2005)
    2. GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease. (PubMed id 21658281)1, 4 Aouizerat B.E....Tseng Z.H. (BMC Cardiovasc Disord 2011)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Common genetic variation and performance on standardized cognitive tests. (PubMed id 20125193)1, 4 Cirulli E.T....Goldstein D.B. (Eur. J. Hum. Genet. 2010)
    5. HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. (PubMed id 19483685)1, 4 Daly A.K.... . (Nat. Genet. 2009)
    6. Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE). (PubMed id 19223264)1, 4 Djurovic S....Andreassen O.A. (Psychiatry Res 2009)
    7. Linkage disequilibrium mapping of a chromosome 15q25-26 major depression linkage region and sequencing of NTRK3. (PubMed id 18367154)1, 4 Verma R....Levinson D.F. (Biol. Psychiatry 2008)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. (PubMed id 23362303)1 Wu J.H....Mozaffarian D. (Circ Cardiovasc Genet 2013)
    10. Genome-wide association study for biomarker identification of Rapamycin and Everolimus using a lymphoblastoid cell line system. (PubMed id 24009623)1 Jiang J....Wang L. (Front Genet 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 55784 HGNC: 25636 AceView: MCTP2 Ensembl:ENSG00000140563 euGenes: HUgn55784
    ECgene: MCTP2 H-InvDB: MCTP2

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for MCTP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for MCTP2 gene:
    Search GeneIP for patents involving MCTP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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