MCRS1 Gene
protein-coding GIFtS: 54
GCID: GC12M049952
|
|
microspherule protein 1
| |
Aliases
for MCRS1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Microspherule Protein 11 2 | | Cell Cycle-Regulated Factor P782 3 | | INO80Q1 2 3 | | 58 KDa Microspherule Protein2 3 | | MCRS21 2 3 | | INO80 Complex Subunit J2 3 | | MSP581 2 3 | | Cell Cycle-Regulated Factor (78 KDa)2 | | ICP22BP1 2 | | INO80 Complex Subunit Q2 | | P781 2 | | |
Export aliases for MCRS1 gene to outside databasesPrevious GC identifers: GC12M050169 GC12M050008 GC12M049668 GC12M048238 GC12M046982 |
Summaries
for MCRS1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: MCRS1_HUMAN, Q96EZ8Function: Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSLcomplex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatorycomponent of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replicationand probably DNA repair. May also be an inhibitor of TERT telomerase activity
Gene Wiki entry for MCRS1
|
Genomic Views
for MCRS1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MCRS1 gene promoter:
E2F E2F-1 E2F-2 NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MCRS1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MCRS1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q13.12 Ensembl cytogenetic band: 12q13.12 HGNC cytogenetic band: 12q13.12MCRS1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12M049952: view genomic region
(about GC identifiers)
Start:
|
49,950,327 bp from pter |
End:
|
49,961,936 bp from pter |
Size:
|
11,610 bases |
Orientation:
|
minus strand |
|
Proteins
for MCRS1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MCRS1_HUMAN, Q96EZ8 (See
protein sequence)Recommended Name: Microspherule protein 1 Size: 462 amino acids; 51803 Da
Subunit: Binds to NOP2, DAXX, PINX1, TERT and Herpes simplex virus ICP22. Interacts with CCDC85B. Component of thechromatin remodeling INO80 complex; specifically part of a complex module associated with the N-terminus of INO80.Component of some MLL1/MLL complex, at least composed of the core components MLL, ASH2L, HCFC1, WDR5 and RBBP5, aswell as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1,PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Component of the NSLcomplex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1
Subcellular location: Nucleus. Nucleus, nucleolus. Note=In microspherules in the nucleolus
Developmental stage: Cell-cycle regulated: levels are highest early in S phase; not detectable in G2
Sequence caution: Sequence=AAC68599.1; Type=Frameshift; Positions=Several;
Secondary accessions: O14742 O75497 Q6VN53Alternative splicing: 3 isoforms: Q96EZ8-1 Q96EZ8-2 Q96EZ8-3 (No experimental confirmation available. May be due to intron retention)Explore the universe of human proteins at neXtProt for MCRS1: NX_Q96EZ8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96EZ8
MCRS1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001012300.1 NP_006328.2
ENSEMBL proteins: ENSP00000448947 ENSP00000447739 ENSP00000345358 ENSP00000448056 ENSP00000448700 ENSP00000349640 ENSP00000447514 ENSP00000450352 ENSP00000449343 ENSP00000447592 ENSP00000444982
Human Recombinant Protein Products for MCRS1:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
MCRS1 for ontologies About GeneDecksing
MCRS1 Antibody Products:
Assay Products for MCRS1: |
Protein
Domains /
Families
for MCRS1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MCRS1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96EZ8ProtoNet protein and cluster: Q96EZ8 1 Blocks protein family: IPB000253 Forkhead-associated (FHA)
UniProtKB/Swiss-Prot: MCRS1_HUMAN, Q96EZ8Similarity: Contains 1 FHA domain |
Function
for MCRS1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: MCRS1_HUMAN, Q96EZ8Function: Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSLcomplex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatorycomponent of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replicationand probably DNA repair. May also be an inhibitor of TERT telomerase activity Genatlas biochemistry entry for MCRS1:microspherule protein 1,nucleolar,associated with the proliferation-related nucleolar protein which is detectable earlyin the G1 phase of the cell cycle and peaks early in the S phase,potentially affecting the size and shape of thenucleolus
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | 19060904 | | GO:0043995 | contributes to histone acetyltransferase activity (H4-K5 specific) |
IDA | -- | | GO:0043996 | contributes to histone acetyltransferase activity (H4-K8 specific) |
IDA | -- | | GO:0046972 | contributes to histone acetyltransferase activity (H4-K16 specific) |
IDA | -- |
MCRS1 for ontologies About GeneDecksing
Phenotypes:
3 GenomeRNAi human phenotypes for MCRS1:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MCRS1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MCRS1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): MCRS1 (NM_001012300) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MCRS1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MCRS1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MCRS1 |
|
Pathways & Interactions
for MCRS1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MCRS1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/100 Interacting proteins for MCRS1 (Q96EZ81, 2, 3 ENSP000003496404) via UniProtKB, MINT, STRING, and/or I2D (see all 100)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| PBX2 | P404252, 3, ENSP000003641904 | MINT-62569 MINT-62667 MINT-62743 I2D:
score=4 STRING: ENSP00000364190 | | CCDC85B | Q158342, 3, ENSP000003116954 | MINT-67453 I2D:
score=5 STRING: ENSP00000311695 | | FXR2 | P511162, 3, ENSP000002501134 | MINT-67809 I2D:
score=5 STRING: ENSP00000250113 | | TRIM37 | O949722, 3, ENSP000002622944 | MINT-67931 I2D:
score=5 STRING: ENSP00000262294 | | WBP11 | Q9Y2W22, 3, ENSP000002611674 | MINT-68385 I2D:
score=5 STRING: ENSP00000261167 |
About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table
MCRS1 for ontologies About GeneDecksing
|
Drugs & Compounds
for MCRS1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MCRS1 for compounds About GeneDecksing
 Browse Tocris compounds for MCRS1
5 Novoseek chemical compound relationships for MCRS1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| bromodeoxyuridine |
13.9 |
1 |
11685767 (1) |
| gnrh |
8.98 |
2 |
8892357 (1) |
| calcium |
0 |
1 |
11043407 (1) |
| estrogen |
0 |
1 |
9264503 (1) |
| ascorbic acid |
0 |
1 |
2134885 (1) |
Search CenterWatch for drugs/clinical trials and news about MCRS1
|
Transcripts
for MCRS1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MCRS1 gene (2 alternative transcripts): NM_001012300.1 NM_006337.3 Unigene Cluster for MCRS1: Microspherule protein 1 Hs.25313 [show with all ESTs]Unigene Representative Sequence: NM_00633716 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000551598 ENST00000548602(uc009zlj.1) ENST00000551625(uc001rui.1 uc001ruj.2)
ENST00000343810(uc001ruk.1) ENST00000550165 ENST00000552596 ENST00000548646
ENST00000547182 ENST00000357123 ENST00000549000 ENST00000553173 ENST00000548334
ENST00000548596 ENST00000549528 ENST00000552206 ENST00000546244
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MCRS1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MCRS1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): MCRS1 (NM_001012300) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MCRS1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MCRS1 |
Additional cDNA sequence: AF015308.1 AK308581.1 AY336730.1 BC011794.2 BX538079.1 19 DOTS entries: DT.91773993 DT.97856875 DT.95368922 DT.100815564 DT.100815577 DT.100815579 DT.91773991 DT.40113414 DT.100815572 DT.100815575 DT.86854215 DT.40110266 DT.117017 DT.100037096 DT.100699067 DT.100830494 DT.95368932 DT.97822491 DT.75127856 24/391 AceView cDNA sequences (see all 391): BI752034 CR596592 C05235 BM798061 BU844840 BI828933 CR618696 BE794097 AL529426 BM710270 CR624177 CR609392 AL535236 BM811539 AI365495 CA867850 BU190176 CA394232 BI223220 AL527338 BX374655 AA099057 CR599933 AL044665
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for MCRS1 (see all 12) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ |
|---|
|
| SP1: | | | | | - | | - | | - | | - | | - | | | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | - | | - | | | | | | | | | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 14 | ^ | 15a | · | 15b | · | 15c | ^ | 16 | ^ | 17a | · | 17b | · | 17c | · | 17d |
|---|
|
| SP1: | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MCRS1
|
Expression
for MCRS1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MCRS1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTGCGGTACC
About this image
See MCRS1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MCRS1
SOURCE GeneReport for Unigene cluster: Hs.25313
UniProtKB/Swiss-Prot: MCRS1_HUMAN, Q96EZ8Tissue specificity: Detected in testis, and at lower levels in spleen, thymus, prostate, uterus, small intestine, colonand leukocytes
SABiosciences Custom PCR Arrays for MCRS1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MCRS1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat MCRS1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MCRS1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MCRS1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MCRS1 |
Orthologs
for MCRS1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for MCRS1 gene from 9/24 species (see all 24) About this table
ENSEMBL Gene Tree for MCRS1 (if available)
TreeFam Gene Tree for MCRS1 (if available) |
Paralogs
for MCRS1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MCRS1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MCRS1 (49950327 - 49961936 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MCRS1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MCRS1 |
|
Disorders
/ Diseases
for MCRS1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MCRS1 for disorders About GeneDecksing
OMIM gene information: 609504
OMIM disorders: --
20/22  diseases for MCRS1 (see all 22): About MalaCardsspinal-bulbar muscular atrophy pigmented basal cell carcinoma ampulla of vater carcinoma severe acute respiratory syndrome
basal cell carcinoma muscular atrophy b-cell lymphomas hepatitis c
herpes simplex embryonal carcinoma retinoblastoma homocysteine
periodontitis carcinoma hepatitis influenza
immunodeficiency breast cancer myeloma hypoxia
8 Novoseek disease relationships for MCRS1 gene About this table
Export disorders for MCRS1 gene to outside databases
|
Publications
for MCRS1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MCRS1 gene, integrated from 9 sources (see all 106):
(articles sorted by number of sources associating them with MCRS1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The 58-kDa microspherule protein (MSP58), a nucleolar protein, interacts with nucleolar protein p120. (PubMed id 9654073)1, 2, 3, 9 Ren Y.... Busch H. (1998)
- Herpes simplex virus 1 regulatory protein ICP22 interacts with a new cell cycle-regulated factor and accumulates in a cell cycle-dependent fashion in infected cells. (PubMed id 9765390)1, 2, 3 Bruni R. and Roizman B. (1998)
- Human MCRS2, a cell-cycle-dependent protein, associates with LPTS/PinX1 and reduces the telomere length. (PubMed id 15044100)1, 2, 9 Song H....Zhao M. (2004)
- Subunit organization of the human INO80 chromatin remodeling complex: An evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling. (PubMed id 21303910)1, 2 Chen L.... Conaway R.C. (2011)
- Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex. (PubMed id 18922472)1, 2 Yao T....Conaway J.W. (2008)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- DIPA, which can localize to the centrosome, associates with p78/MCRS1/MSP58 and acts as a repressor of gene transcription. (PubMed id 17014843)1, 2 Du X.... Greene M.I. (2006)
- Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. (PubMed id 15960975)1, 2 Dou Y.... Roeder R.G. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Essential role of the 58-kDa microspherule protein in the modulation of Daxx-dependent transcriptional repression as revealed by nucleolar sequestration. (PubMed id 11948183)1, 2 Lin D.-Y. and Shih H.-M. (2002)
|
External Searches for MCRS1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MCRS1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MCRS1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MCRS1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MCRS1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MCRS1 gene:
Search GeneIP for patents involving MCRS1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for MCRS1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | OriGene Antibodies for MCRS1 | | OriGene shRNA RFP for MCRS1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MCRS1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MCRS1 | | | OriGene Protein Over-expression Lysate for MCRS1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MCRS1 | | OriGene 3'-UTR Clone for MCRS1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MCRS1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MCRS1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MCRS1 | | OriGene Custom Protein Services for MCRS1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MCRS1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MCRS1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MCRS1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MCRS1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MCRS1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MCRS1 |
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| | | | Search Tocris compounds for MCRS1 |
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 | | | MCRS1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MCRS1 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for MCRS1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MCRS1 |
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