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Aliases for MCRIP2 Gene

Aliases for MCRIP2 Gene

  • MAPK Regulated Co-Repressor Interacting Protein 2 2 3
  • Family With Sequence Similarity 195 Member A 2 3 5
  • FAM195A 3 4 5
  • Family With Sequence Similarity 195, Member A 2 3
  • C16orf14 3 4
  • Chromosome 16 Open Reading Frame 14 2
  • C349E10.1 3

External Ids for MCRIP2 Gene

Previous HGNC Symbols for MCRIP2 Gene

  • C16orf14
  • FAM195A

Summaries for MCRIP2 Gene

GeneCards Summary for MCRIP2 Gene

MCRIP2 (MAPK Regulated Co-Repressor Interacting Protein 2) is a Protein Coding gene. Diseases associated with MCRIP2 include Hepatic Tuberculosis and Granulomatous Hepatitis. An important paralog of this gene is MCRIP1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MCRIP2 Gene

Genomics for MCRIP2 Gene

Regulatory Elements for MCRIP2 Gene

Enhancers for MCRIP2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MCRIP2 on UCSC Golden Path with GeneCards custom track

Promoters for MCRIP2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MCRIP2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MCRIP2 Gene

636,817 bp from pter
648,474 bp from pter
11,658 bases
Plus strand

Genomic View for MCRIP2 Gene

Genes around MCRIP2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MCRIP2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MCRIP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MCRIP2 Gene

Proteins for MCRIP2 Gene

  • Protein details for MCRIP2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM195A
    Protein Accession:
    Secondary Accessions:
    • Q969E9
    • Q96KV8

    Protein attributes for MCRIP2 Gene

    160 amino acids
    Molecular mass:
    17828 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MCRIP2 Gene


neXtProt entry for MCRIP2 Gene

Proteomics data for MCRIP2 Gene at MOPED

Post-translational modifications for MCRIP2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MCRIP2 Gene

No data available for DME Specific Peptides for MCRIP2 Gene

Domains & Families for MCRIP2 Gene

Protein Domains for MCRIP2 Gene


Suggested Antigen Peptide Sequences for MCRIP2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM195 family.
  • Belongs to the FAM195 family.
genes like me logo Genes that share domains with MCRIP2: view

No data available for Gene Families for MCRIP2 Gene

Function for MCRIP2 Gene

Phenotypes for MCRIP2 Gene

GenomeRNAi human phenotypes for MCRIP2:
genes like me logo Genes that share phenotypes with MCRIP2: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MCRIP2 Gene

Localization for MCRIP2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MCRIP2 Gene

Pathways & Interactions for MCRIP2 Gene

SuperPathways for MCRIP2 Gene

No Data Available

Interacting Proteins for MCRIP2 Gene

Selected Interacting proteins: Q9BUT9-F195A_HUMAN for MCRIP2 Gene via I2D

Gene Ontology (GO) - Biological Process for MCRIP2 Gene


No data available for Pathways by source and SIGNOR curated interactions for MCRIP2 Gene

Drugs & Compounds for MCRIP2 Gene

No Compound Related Data Available

Transcripts for MCRIP2 Gene

Unigene Clusters for MCRIP2 Gene

Family with sequence similarity 195, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MCRIP2 Gene

No ASD Table

Relevant External Links for MCRIP2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MCRIP2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for MCRIP2 Gene Hs.706105

genes like me logo Genes that share expression patterns with MCRIP2: view

Primer Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MCRIP2 Gene

Orthologs for MCRIP2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MCRIP2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM195A 35
  • 91.18 (n)
  • 91.61 (a)
FAM195A 36
  • 89 (a)
(Mus musculus)
Mammalia Fam195a 35
  • 85.83 (n)
  • 85 (a)
Fam195a 16
Fam195a 36
  • 85 (a)
(Pan troglodytes)
Mammalia FAM195A 35
  • 99.37 (n)
  • 99.37 (a)
FAM195A 36
  • 79 (a)
(Rattus norvegicus)
Mammalia Fam195a 35
  • 87.5 (n)
  • 85 (a)
(Canis familiaris)
Mammalia FAM195A 36
  • 86 (a)
(Monodelphis domestica)
Mammalia FAM195A 36
  • 76 (a)
(Gallus gallus)
Aves FAM195A 35
  • 73.43 (n)
  • 65.73 (a)
FAM195A 36
  • 62 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam195a 35
  • 57.41 (n)
  • 54.86 (a)
(Danio rerio)
Actinopterygii si:dkey-44g23.5 35
  • 67.38 (n)
  • 62.86 (a)
FAM195A 36
  • 60 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10574 35
Species with no ortholog for MCRIP2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MCRIP2 Gene

Gene Tree for MCRIP2 (if available)
Gene Tree for MCRIP2 (if available)

Paralogs for MCRIP2 Gene

Paralogs for MCRIP2 Gene Pseudogenes for MCRIP2 Gene

genes like me logo Genes that share paralogs with MCRIP2: view

Variants for MCRIP2 Gene

Sequence variations from dbSNP and Humsavar for MCRIP2 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs62030957 -- 646,081(+) CCAGA(G/T)AGCAG intron-variant
rs9940108 -- 646,499(+) ACCGA(A/G)AGCGG intron-variant
rs1810458 -- 645,287(+) AGTCT(C/T)GCTCT intron-variant
rs72767895 -- 645,698(+) GGGAC(C/T)GCCAC intron-variant
rs34281779 -- 643,849(+) TCCCC(-/C)ATGTG intron-variant

Variation tolerance for MCRIP2 Gene

Gene Damage Index Score: 0.32; 7.06% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for MCRIP2 Gene

Disorders for MCRIP2 Gene

MalaCards: The human disease database

(2) MalaCards diseases for MCRIP2 Gene - From: DISEASES

Disorder Aliases PubMed IDs
hepatic tuberculosis
  • tuberculosis of liver
granulomatous hepatitis
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MCRIP2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MCRIP2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MCRIP2 Gene

Publications for MCRIP2 Gene

  1. Comprehensive Protein Interactome Analysis of a Key RNA Helicase: Detection of Novel Stress Granule Proteins. (PMID: 26184334) Bish R. … Vogel C. (Biomolecules 2015) 2 3 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  5. TRIM65 regulates microRNA activity by ubiquitination of TNRC6. (PMID: 24778252) Li S. … Dorf M.E. (Proc. Natl. Acad. Sci. U.S.A. 2014) 3

Products for MCRIP2 Gene

Sources for MCRIP2 Gene