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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MCOLN2 Gene

protein-coding   GIFtS: 49
GCID: GC01M085391

Mucolipin 2

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Mucolipin 21 2
TRP-ML22
TRPML22
mucolipin-22

External Ids:    HGNC: 133571   Entrez Gene: 2552312   Ensembl: ENSG000001538987   OMIM: 6073995   UniProtKB: Q8IZK63   

Export aliases for MCOLN2 gene to outside databases

Previous GC identifers: GC01M084529 GC01M084679 GC01M084814 GC01M084813 GC01M085103 GC01M083501


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MCOLN2 Gene:
Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential
superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM
607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila
and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al., 2007
(PubMed 17662026)).(supplied by OMIM, Sep 2009)

GeneCards Summary for MCOLN2 Gene: 
MCOLN2 (mucolipin 2) is a protein-coding gene. Diseases associated with MCOLN2 include mucolipidosis. An important paralog of this gene is MCOLN3.

Gene Wiki entry for MCOLN2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MCOLN2 gene promoter:
         AREB6   Max   N-Myc   Sp1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMCOLN2 promoter sequence
   Search SABiosciences Chromatin IP Primers for MCOLN2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MCOLN2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p22   Ensembl cytogenetic band:  1p22.3   HGNC cytogenetic band: 1p22

MCOLN2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MCOLN2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M085391:  view genomic region     (about GC identifiers)

Start:
85,391,266 bp from pter      End:
85,462,796 bp from pter
Size:
71,531 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MCLN2_HUMAN, Q8IZK6 (See protein sequence)
Recommended Name: Mucolipin-2  
Size: 566 amino acids; 65942 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Sequence caution: Sequence=BAC04267.1; Type=Erroneous termination; Positions=64; Note=Translated as Trp;
Secondary accessions: A6NI99 Q2M3I6 Q5TAG5 Q8N9R3
Alternative splicing: 2 isoforms:  Q8IZK6-1   Q8IZK6-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MCOLN2: NX_Q8IZK6

Explore proteomics data for MCOLN2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8IZK6

  • MCOLN2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MCOLN2 Protein Expression
    REFSEQ proteins: NP_694991.2  
    ENSEMBL proteins: 
     ENSP00000359640   ENSP00000436299   ENSP00000284027  

    Human Recombinant Protein Products for MCOLN2: 
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    OriGene Protein Over-expression Lysate for MCOLN2
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    Novus Biologicals MCOLN2 Lysate
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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for MCOLN2 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--

    MCOLN2 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for MCOLN2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    TRP: Voltage-gated ion channels / Transient receptor potential cation channels

    IUPHAR Guide to PHARMACOLOGY protein family classification: TRPML2 
    Transient Receptor Potential channels

    1 InterPro protein domain:
     IPR013122 PKD1_2_channel

    Graphical View of Domain Structure for InterPro Entry Q8IZK6

    ProtoNet protein and cluster: Q8IZK6

    UniProtKB/Swiss-Prot: MCLN2_HUMAN, Q8IZK6
    Similarity: Belongs to the transient receptor (TC 1.A.4) family. Polycystin subfamily. MCOLN2 sub-subfamily


    MCOLN2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MCOLN2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MCOLN2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MCOLN2 
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    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MCOLN2
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate MCOLN2 (see all 13):
    hsa-miR-374b* hsa-miR-26a-2* hsa-miR-92a hsa-miR-513a-3p hsa-miR-25 hsa-miR-367 hsa-miR-32 hsa-miR-146a*
    SwitchGear 3'UTR luciferase reporter plasmidMCOLN2 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Gene Editing
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MCOLN2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MCOLN2

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811ion transport IEA--

    MCOLN2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MCOLN2 (MCLN2)

    Search CenterWatch for drugs/clinical trials and news about MCOLN2 / MCLN2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MCOLN2 gene: 
    NM_153259.2  

    Unigene Cluster for MCOLN2:

    Mucolipin 2
    Hs.591446  [show with all ESTs]
    Unigene Representative Sequence: NM_153259
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000370608(uc001dkm.3 uc001dkn.3) ENST00000463065 ENST00000530971
    ENST00000284027 ENST00000531325 ENST00000531874
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MCOLN2
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate MCOLN2 (see all 13):
    hsa-miR-374b* hsa-miR-26a-2* hsa-miR-92a hsa-miR-513a-3p hsa-miR-25 hsa-miR-367 hsa-miR-32 hsa-miR-146a*
    SwitchGear 3'UTR luciferase reporter plasmidMCOLN2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MCOLN2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MCOLN2
    Clone
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    OriGene clones in human, mouse for MCOLN2 (see all 7)
    OriGene ORF clones in mouse, rat for MCOLN2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MCOLN2 (NM_153259)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MCOLN2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MCOLN2
    Sirion Biotech Customized lentivirus for stable overexpression of MCOLN2 
                         Customized lentivirus expression plasmids for stable overexpression of MCOLN2 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for MCOLN2
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MCOLN2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MCOLN2

    Additional mRNA sequence: 

    AK094010.1 AK129786.1 AK309858.1 AY083533.1 BC104891.1 BC104893.1 

    4 DOTS entries:

    DT.100019001  DT.439511  DT.87015366  DT.121418605 

    24/27 AceView cDNA sequences (see all 27):

    BP354472 AY083533 AV713773 BX115566 AK129786 AA664369 AI128274 AI128279 
    AW119125 BG122048 BV206882 AK094010 N41861 AI222682 AX748410 AI160827 
    AW377181 AI914009 AI915368 AI458257 N41435 BM999217 BQ678209 AA740983 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for MCOLN2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b · 13c
    SP1:                                                                                -                           
    SP2:                                      -           -     -                       -                           
    SP3:                                                                                                            


    ECgene alternative splicing isoforms for MCOLN2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MCOLN2 expression in normal human tissues (normalized intensities)      MCOLN2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    MCOLN2 Expression
    About this image


    MCOLN2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Chondrocytes Zeugopod Epiphyseal End
             Zeugopod Growth Plate
     
     Heart (Cardiovascular System)
             Mature Cardiac Fibroblasts Myocardium
     
     Blood (Hematopoietic System)
             CD19+ B Cells   
     
     Cartilage (Muscoskeletal System)
             Chondrocytes Zeugopod Epiphyseal End

    See MCOLN2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MCOLN2

    SOURCE GeneReport for Unigene cluster: Hs.591446
        SABiosciences Custom PCR Arrays for MCOLN2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MCOLN2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for MCOLN2 gene from 7/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mcoln21 , 5 mucolipin 21, 5 83.46(n)1
    83.7(a)1
      3 (71.03 cM)5
    682791  NM_026656.41  NP_080932.21 
     1461498335 
    chicken
    (Gallus gallus)
    Aves MCOLN21 mucolipin 2 75.34(n)
    76.01(a)
      424531  XM_422368.3  XP_422368.2 
    lizard
    (Anolis carolinensis)
    Reptilia MCOLN26
    Uncharacterized protein
    76(a)
    1 ↔ 1
    GL343194.1(10043229-10065854)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.17072 Xenopus laevis transcribed sequence with weak similarity more 78.55(n)    CF520914.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc553102 similar to mucolipin 2 75.44(n)   394123  BC044140.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta trpml6
    CG426386
    --
    30(a)
    30(a)
    many ↔ many
    many ↔ many
    3L(19707518-19711428)
    3L(19738934-19742819)
    worm
    (Caenorhabditis elegans)
    Secernentea cup-56
    Protein CUP-5, isoform c
    26(a)
    1 → many
    III(7584181-7591576)


    ENSEMBL Gene Tree for MCOLN2 (if available)
    TreeFam Gene Tree for MCOLN2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MCOLN2 gene
    MCOLN32  MCOLN12  
    2 SIMAP similar genes for MCOLN2 using alignment to 2 protein entries:     MCLN2_HUMAN (see all proteins):
    MCOLN3    MCOLN1

    MCOLN2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1659 SNPs in MCOLN2 are shown (see all 1659)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs745958741,2
    --85409319(+) TATAGC/TTGGTG 1 -- ds50010--------
    rs1858198341,2
    --85409405(+) GGAGGA/GCGACT 1 -- ds50010--------
    rs1902794361,2
    --85409451(+) GGGTCA/CTGCTT 1 -- ds50010--------
    rs1441645791,2
    --85409567(+) CATCAA/TAAATA 1 -- ds50010--------
    rs37385721,2
    C,F,A,H--85409608(-) AAGGAT/CATACA 1 -- ds500140Minor allele frequency- C:0.50EA NA NS WA CSA 4877
    rs1459948101,2
    --85409681(+) TGAATA/GTTTCA 1 -- ds50010--------
    rs1399402221,2
    --85409839(+) TGACCA/GCTGCT 1 -- ut310--------
    rs740987161,2
    C,F--85409865(+) ATGTCA/GTGTGT 1 -- ut312Minor allele frequency- G:0.05WA 120
    rs785678101,2
    F--85409897(+) AGTGAC/TGAGGC 1 -- ut310--------
    rs1820483131,2
    --85409963(+) TATCAC/TGCTGA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for MCOLN2 (85391266 - 85462796 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for MCOLN2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv267474CNV Insertion20981092
    nsv830448CNV Loss17160897
    nsv470724CNV Gain18288195
    nsv462383CNV Gain19166990

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing MCOLN2
    DNA2.0 Custom Variant and Variant Library Synthesis for MCOLN2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607399    OMIM disorders: --

    2 diseases for MCOLN2:    About MalaCards
    mucolipidosis    

    1 disease from the University of Copenhagen DISEASES database for MCOLN2:
    Mucolipidosis

    MCOLN2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MCOLN2
    Human Genome Epidemiology (HuGE) Navigator: MCOLN2 (1 document)

    Export disorders for MCOLN2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MCOLN2 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with MCOLN2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    2. International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels. (PubMed id 16382100)1, 3 Clapham D.E....Schultz G. (2005)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice. (PubMed id 12403827)1, 2 Di Palma F....Noben-Trauth K. (2002)
    5. Functional multimerization of mucolipin channel prote ins. (PubMed id 19885840)1, 9 Curcio-Morelli C....Slaugenhaupt S.A. (2010)
    6. Constitutive activity of TRPML2 and TRPML3 channels ve rsus activation by low extracellular sodium and small molecules. (PubMed id 22753890)1 Grimm C....Heller S. (2012)
    7. Heteromultimeric TRPML channel assemblies play a cruc ial role in the regulation of cell viability models and starvation-induced auto phagy. (PubMed id 20736310)1 Zeevi D.A....Bach G. (2010)
    8. Constitutive activity of the human TRPML2 channel ind uces cell degeneration. (PubMed id 19940139)1 Lev S....Minke B. (2010)
    9. The tissue-specific expression of TRPML2 (MCOLN-2) ge ne is influenced by the presence of TRPML1. (PubMed id 19763610)1 Samie M.A....Cuajungco M.P. (2009)
    10. Mucolipin-2 localizes to the Arf6-associated pathway and regulates recycling of GPI-APs. (PubMed id 17662026)1 Karacsonyi C....Puertollano R. (2007)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 255231 HGNC: 13357 AceView: MCOLN2 Ensembl:ENSG00000153898 euGenes: HUgn255231
    ECgene: MCOLN2 H-InvDB: MCOLN2

    (According to HUGE)
    About This Section
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MCOLN2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MCOLN2 gene:
    Search GeneIP for patents involving MCOLN2

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