Aliases for MCMBP Gene
External Ids for MCMBP Gene
Previous HGNC Symbols for MCMBP Gene
Previous GeneCards Identifiers for MCMBP Gene
This gene encodes a protein which is a component of the hexameric minichromosome maintenance (MCM) complex which regulates initiation and elongation of DNA. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
GeneCards Summary for MCMBP Gene
MCMBP (Minichromosome Maintenance Complex Binding Protein) is a Protein Coding gene. GO annotations related to this gene include chromatin binding.
UniProtKB/Swiss-Prot for MCMBP Gene
Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion.