Aliases for MCIDAS Gene
External Ids for MCIDAS Gene
Previous HGNC Symbols for MCIDAS Gene
Previous GeneCards Identifiers for MCIDAS Gene
GeneCards Summary for MCIDAS Gene
MCIDAS (Multiciliate Differentiation And DNA Synthesis Associated Cell Cycle Protein) is a Protein Coding gene. Diseases associated with MCIDAS include Mucociliary Clearance Disorder and Bronchiectasis. GO annotations related to this gene include identical protein binding and transcription coactivator activity.
UniProtKB/Swiss-Prot for MCIDAS Gene
Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway (PubMed:25048963). Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1 (PubMed:21543332, PubMed:24064211).