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MCF2L2 Gene

protein-coding   GIFtS: 51
GCID: GC03M182895

MCF.2 Cell Line Derived Transforming Sequence-Like 2

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
MCF.2 Cell Line Derived Transforming Sequence-Like 21 2     Probable Guanine Nucleotide Exchange Factor MCF2L22
Dbs-Related Rho Family Guanine Nucleotide Exchange Factor2 3     DRG3
MCF2-Transforming Sequence-Like Protein 22 3     KIAA08613
ARHGEF222     

External Ids:    HGNC: 303191   Entrez Gene: 231012   Ensembl: ENSG000000535247   UniProtKB: Q86YR73   

Export aliases for MCF2L2 gene to outside databases

Previous GC identifers: GC03M184378 GC03M180301


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MCF2L2 Gene:
MCF2L2 (MCF.2 cell line derived transforming sequence-like 2) is a protein-coding gene. GO annotations related to this gene include phospholipid binding and Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is KALRN.

UniProtKB/Swiss-Prot: MF2L2_HUMAN, Q86YR7
Function: Probably functions as a guanine nucleotide exchange factor (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NC_018914.2  NT_005612.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the MCF2L2 gene promoter:
         En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMCF2L2 promoter sequence
   Search Chromatin IP Primers for MCF2L2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MCF2L2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q27.1   Ensembl cytogenetic band:  3q27.1   HGNC cytogenetic band: 3q27

MCF2L2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MCF2L2 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M182895:  view genomic region     (about GC identifiers)

Start:
182,895,831 bp from pter      End:
183,146,566 bp from pter
Size:
250,736 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: MF2L2_HUMAN, Q86YR7 (See protein sequence)
Recommended Name: Probable guanine nucleotide exchange factor MCF2L2  
Size: 1114 amino acids; 126993 Da
Sequence caution: Sequence=AAO19651.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: O94942 Q6P2B8 Q6ZVJ5 Q8N318
Alternative splicing: 4 isoforms:  Q86YR7-1   Q86YR7-2   Q86YR7-3   Q86YR7-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MCF2L2: NX_Q86YR7

Explore proteomics data for MCF2L2 at MOPED


See MCF2L2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_055893.3  
ENSEMBL proteins: 
 ENSP00000328118   ENSP00000420070   ENSP00000388190   ENSP00000414131   ENSP00000417345  

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Cloud-Clone Corp. ELISAs for MCF2L2
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Search eBioscience for ELISAs for MCF2L2 
antibodies-online kits for MCF2L2 (2 products) 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
ARHGEF: Rho guanine nucleotide exchange factors

5 InterPro protein domains:
 IPR000219 DH-domain
 IPR001849 Pleckstrin_homology
 IPR001251 CRAL-TRIO_dom
 IPR011993 PH_like_dom
 IPR018159 Spectrin/alpha-actinin

Graphical View of Domain Structure for InterPro Entry Q86YR7

ProtoNet protein and cluster: Q86YR7

2 Blocks protein domains:
IPB000219 DH domain
IPB001849 Pleckstrin-like


UniProtKB/Swiss-Prot: MF2L2_HUMAN, Q86YR7
Similarity: Belongs to the MCF2 family
Similarity: Contains 1 CRAL-TRIO domain
Similarity: Contains 1 DH (DBL-homology) domain
Similarity: Contains 1 PH domain
Similarity: Contains 1 spectrin repeat


Find genes that share domains with MCF2L2           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: MF2L2_HUMAN, Q86YR7
Function: Probably functions as a guanine nucleotide exchange factor (By similarity)

     Gene Ontology (GO): 2 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005089Rho guanyl-nucleotide exchange factor activity IEA--
GO:0005515protein binding ----
     
Find genes that share ontologies with MCF2L2           About GenesLikeMe


Phenotypes:
     3 GenomeRNAi human phenotypes for MCF2L2:
 Cell division defect  Increased G2M DNA content  Increased number of mitotic ce 

Animal Models:
   genOway: Develop your customized and physiologically relevant rodent model for MCF2L2

miRNA
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5 qRT-PCR Assays for microRNAs that regulate MCF2L2:
hsa-miR-3163 hsa-miR-3132 hsa-miR-219-5p hsa-miR-548c-3p hsa-miR-508-3p
SwitchGear 3'UTR luciferase reporter plasmidMCF2L2 3' UTR sequence
Inhib. RNA
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytosol3
nucleus2
cytoskeleton1
peroxisome1
plasma membrane1

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MCF2L2
Interactions:

    Search GeneGlobe Interaction Network for MCF2L2

STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

Selected Interacting proteins for MCF2L2 (Q86YR73 ENSP000003281184) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
InteractantInteraction Details
GeneCardExternal ID(s)
SIRT1Q96EB63, ENSP000002120154I2D: score=2 STRING: ENSP00000212015
MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
MEGF10Q96KG73, ENSP000002744734I2D: score=2 STRING: ENSP00000274473
RASL10BENSP000002688644STRING: ENSP00000268864
RAB19ENSP000002758744STRING: ENSP00000275874
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Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0035023regulation of Rho protein signal transduction ----

Find genes that share ontologies with MCF2L2           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for MCF2L2 (MF2L2)

3 HMDB Compounds for MCF2L2    About this table
CompoundSynonyms CAS #PubMed Ids
Guanosine diphosphate5'-GDP (see all 10)146-91-8--
Guanosine monophosphate5'-GMP (see all 14)85-32-5--
Guanosine triphosphate5'-GTP (see all 10)86-01-1--



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for MCF2L2 gene: 
NM_015078.3  

Unigene Cluster for MCF2L2:

MCF.2 cell line derived transforming sequence-like 2
Hs.208267  [show with all ESTs]
Unigene Representative Sequence: BX649003
13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000328913(uc003fli.1) ENST00000473233 ENST00000478652 ENST00000464626
ENST00000468976 ENST00000488149(uc011bqr.1) ENST00000447025(uc003flj.1 uc011bqs.1)
ENST00000414362 ENST00000475664 ENST00000459750(uc003flp.1) ENST00000492331
ENST00000482017 ENST00000461074
miRNA
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5 qRT-PCR Assays for microRNAs that regulate MCF2L2:
hsa-miR-3163 hsa-miR-3132 hsa-miR-219-5p hsa-miR-548c-3p hsa-miR-508-3p
SwitchGear 3'UTR luciferase reporter plasmidMCF2L2 3' UTR sequence
Inhib. RNA
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  QuantiFast Probe-based Assays in human, mouse, rat MCF2L2

Additional mRNA sequence: 

AB020668.1 AK124500.1 AK301698.1 AK310962.1 AY172737.1 BC029074.2 BC064632.1 BX647790.1 
BX648525.1 BX649003.1 

15 DOTS entries:

DT.91907482  DT.97837559  DT.311018  DT.102842877  DT.101978686  DT.75129021  DT.86849491  DT.92028182 
DT.99936716  DT.120868409  DT.120868411  DT.92022931  DT.95162130  DT.97792580  DT.91855366 

Selected AceView cDNA sequences (see all 56):

CD367113 AI074993 NM_015078 BX642438 CA848316 BX487485 BU685704 AK124500 
BU683997 BU685601 BX647790 AW368783 AA352505 AA325939 BX109053 BC029074 
CA848607 BG184963 AB020668 AY172737 BC064632 AI370362 BI460415 BG192266 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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MCF2L2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
MCF2L2 Expression
About this image


MCF2L2 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 
 NULL (Uncategorized)
         Definitive endoderm-like cells
MCF2L2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

MCF2L2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.208267

UniProtKB/Swiss-Prot: MF2L2_HUMAN, Q86YR7
Tissue specificity: Significantly expressed in brain and modestly in pancreas, brain and testis

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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MCF2L2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for MCF2L2 gene from Selected species (see all 11)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
dog
(Canis familiaris)
Mammalia MCF2L21 MCF.2 cell line derived transforming sequence-like more 86.99(n)
83.86(a)
  478646  XM_005639762.1  XP_005639819.1 
chicken
(Gallus gallus)
Aves MCF2L26
MCF.2 cell line derived transforming sequence-like...
50(a)
1 ↔ 1
9(15742979-15839708)
lizard
(Anolis carolinensis)
Reptilia MCF2L26
MCF.2 cell line derived transforming sequence-like...
49(a)
1 ↔ 1
3(15942-152944)
zebrafish
(Danio rerio)
Actinopterygii MCF2L26
MCF.2 cell line derived transforming sequence-like...
49(a)
1 ↔ 1
11(10533584-10722703) ENSDARG00000079742
fruit fly
(Drosophila melanogaster)
Insecta CG304406
--
19(a)
1 → many
2R(1355819-1383341)
worm
(Caenorhabditis elegans)
Secernentea cgef-16
Protein CGEF-1, isoform b (cgef-1) mRNA, complete ...
24(a)
1 → many
X(2772042-2799243) WBGene00006496


ENSEMBL Gene Tree for MCF2L2 (if available)
TreeFam Gene Tree for MCF2L2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for MCF2L2 gene
KALRN2  ARHGEF252  PLEKHG4B2  TRIO2  MCF2L2  KIAA17552  PLEKHG42  ARHGEF402  
MCF22  
5 SIMAP similar genes for MCF2L2 using alignment to 2 protein entries:     MF2L2_HUMAN (see all proteins):
MCF2L    TRIO    MCF2    tgat    SESTD1

Find genes that share paralogs with MCF2L2           About GenesLikeMe


1 Pseudogenes.org Pseudogene for MCF2L2
PGOHUM00000238296


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for MCF2L2 (see all 4917)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 3 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0435934
A colorectal cancer sample4--see VAR_0435932 R H mis40--------
VAR_0435974
A breast cancer sample4--see VAR_0435972 L F mis40--------
VAR_0435884
A colorectal cancer sample4--see VAR_0435882 L P mis40--------
rs1897582191,2
--182895340(+) GGTGCC/TTGTAA 1 -- ds50010--------
rs1811762211,2
--182895362(+) TGGGAA/GGCTGA 1 -- ds50010--------
rs1387008661,2
--182895390(+) AACCCA/GGGAGG 1 -- ds50010--------
rs1128191831,2
C,F--182895397(+) GAGGCG/AGAGGT 1 -- ds50011Minor allele frequency- A:0.50WA 2
rs1508024531,2
C--182895457(+) CAAAAC/TTCCAT 1 -- ds50010--------
rs1865341071,2
--182895477(+) AAAAAA/GAAAGA 1 -- ds50010--------
rs1999578651,2
--182895550(+) AAAAG-/AAAT  
        
AACTG
1 -- ds50010--------

HapMap Linkage Disequilibrium report for MCF2L2 (182895831 - 183145831 bp, first 250kb of MCF2L2)

Structural Variations
     Database of Genomic Variants (DGV) Selected variations for MCF2L2 (see all 16):    About this table    
Variant IDTypeSubtypePubMed ID
esv1507474CNV Deletion17803354
dgv899e199CNV Deletion23128226
esv2726290CNV Deletion23290073
esv996921CNV Deletion20482838
esv2726288CNV Deletion23290073
esv2726289CNV Deletion23290073
esv2726291CNV Deletion23290073
esv1779554CNV Insertion17803354
esv2583133CNV Insertion19546169
nsv4142CNV Insertion18451855

Human Gene Mutation Database (HGMD): MCF2L2
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing MCF2L2
DNA2.0 Custom Variant and Variant Library Synthesis for MCF2L2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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UniProtKB/Swiss-Prot: MF2L2_HUMAN, Q86YR7
  • Diabetes mellitus, non-insulin-dependent (NIDDM) [MIM:125853]: A multifactorial disorder of glucose
    homeostasis caused by a lack of sensitivity to the body's own insulin. Affected individuals usually have an obese
    body habitus and manifestations of a metabolic syndrome characterized by diabetes, insulin resistance,
    hypertension and hypertriglyceridemia. The disease results in long-term complications that affect the eyes,
    kidneys, nerves, and blood vessels. Note=Disease susceptibility may be associated with variations affecting the
    gene represented in this entry


  • Find genes that share disorders with MCF2L2           About GenesLikeMe

    Genetic Association Database (GAD): MCF2L2
    Human Genome Epidemiology (HuGE) Navigator: MCF2L2 (4 documents)

    Export disorders for MCF2L2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MCF2L2 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with MCF2L2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Search for type 2 diabetes susceptibility genes on chromosomes 1q, 3q and 12q. (PubMed id 18259684)1, 2, 4 Takeuchi F.... Kato N. (J. Hum. Genet. 2008)
    2. Family-based association study of the MCF2L2 gene and polycystic ovary syndrome. (PubMed id 19648752)1, 4, 9 Zheng Q....Chen Z.J. (Gynecol. Obstet. Invest. 2009)
    3. Effects of MCF2L2, ADIPOQ and SOX2 genetic polymorphisms on the development of nephropathy in type 1 Diabetes Mellitus. (PubMed id 20667095)1, 4 Zhang D....Gu H.F. (BMC Med. Genet. 2010)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)1, 2 Nagase T.... Ohara O. (DNA Res. 1998)
    6. Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with BehAset's disease. (PubMed id 20622878)4 Remmers E.F....GA1l A. (Nat. Genet. 2010)
    7. Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins. (PubMed id 19343720)1 Law I.K....Wang Y. (Proteomics 2009)
    8. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)
    9. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (Nature 2006)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23101 HGNC: 30319 AceView: MCF2L2 Ensembl:ENSG00000053524 euGenes: HUgn23101
    ECgene: MCF2L2 H-InvDB: MCF2L2

    (According to HUGE)
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    HUGE: KIAA0861

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MCF2L2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MCF2L2 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MCF2L2 gene:
    Search GeneIP for patents involving MCF2L2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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