MCF2L Gene
protein-coding GIFtS: 62
GCID: GC13P113548
|
|
MCF.2 cell line derived transforming sequence-like
| |
Aliases
for MCF2L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| MCF.2 Cell Line Derived Transforming Sequence-Like1 2 | | DBL'S Big Sister2 3 | | ARHGEF141 2 | | Guanine Nucleotide Exchange Factor DBS2 | | DBS1 2 | | MCF2 Transforming Sequence-Like Protein2 | | OST1 2 | | MCF2-Transforming Sequence-Like Protein3 | | KIAA03621 3 | | |
Export aliases for MCF2L gene to outside databasesPrevious GC identifers: GC13P112232 GC13U900016 GC13P112709 GC13P111570 GC13P112670 GC13P094063 |
Summaries
for MCF2L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: MCF2L_HUMAN, O15068Function: Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42.Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1,suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomesactivated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42
Gene Wiki entry for MCF2L
|
Genomic Views
for MCF2L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000013.10 NC_018924.1 NT_027140.6
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MCF2L gene promoter:
Bach1 GATA-3 FOXD1 HNF-1A GATA-1 GATA-2 CREB c-Rel
Other transcription factors
Search SABiosciences Chromatin IP Primers for MCF2L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MCF2L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 13q34 Ensembl cytogenetic band: 13q34 HGNC cytogenetic band: 13q34MCF2L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13P113548: view genomic region
(about GC identifiers)
Start:
|
113,548,692 bp from pter |
End:
|
113,754,053 bp from pter |
Size:
|
205,362 bases |
Orientation:
|
plus strand |
|
Proteins
for MCF2L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MCF2L_HUMAN, O15068 (See
protein sequence)Recommended Name: Guanine nucleotide exchange factor DBS Size: 1137 amino acids; 128109 Da
Subunit: Interacts with CCPG1, which results in specific inhibition of its exchange activity toward RHOA (Bysimilarity). Interacts with an array of inositol phospholipids such as phosphatidylinositol 3-phosphate (PI3P),phosphatidylinositol 4-phosphate (PI4P) and phosphatidylinositol 5-phosphate (PI5P)
Subcellular location: Cytoplasm (By similarity). Cell membrane; Peripheral membrane protein; Cytoplasmic side (Bysimilarity)
Sequence caution: Sequence=BAA20817.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;Sequence=CAM24069.3; Type=Erroneous gene model prediction; Sequence=CAM24070.1; Type=Erroneous gene model prediction;
Secondary accessions: A2A2X1 A2A2X2 A2A3G6 A2A3G8 B4DHD6 B4DIL6 E9PDN8 Q5JU56 Q5VXT1 Q6ZWD4 Q765G8Q765G9 Q8N679Alternative splicing: 9 isoforms: O15068-1 O15068-2 O15068-3 O15068-4 O15068-5 O15068-6 O15068-9 O15068-8 O15068-10 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MCF2L: NX_O15068
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O15068
MCF2L Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001106203.2 NP_079255.4
ENSEMBL proteins: ENSP00000364758 ENSP00000380230 ENSP00000398383 ENSP00000380225 ENSP00000440374 ENSP00000397285 ENSP00000395707 ENSP00000386551 ENSP00000364747 ENSP00000380219 ENSP00000380216 ENSP00000405996 ENSP00000380212 ENSP00000407392 ENSP00000261963 ENSP00000392953 ENSP00000411315 ENSP00000404422 ENSP00000395978 ENSP00000401422 ENSP00000364754 ENSP00000364751 ENSP00000407722 ENSP00000405639 Reactome Protein details: O15068
Human Recombinant Protein Products for MCF2L:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
MCF2L for ontologies About GeneDecksing
MCF2L Antibody Products:
Assay Products for MCF2L: |
Protein
Domains /
Families
for MCF2L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MCF2L for domains About GeneDecksing
5/9 InterPro domains/families (see all 9):Graphical View of Domain Structure for InterPro Entry O15068ProtoNet protein and cluster: O15068 3 Blocks protein families: IPB000219 DH domain IPB001849 Pleckstrin-like IPB002017 Spectrin repeat
UniProtKB/Swiss-Prot: MCF2L_HUMAN, O15068Domain: The CRAL-TRIO domain is involved in interaction with inositol phospholipidsDomain: The DH domain is involved in interaction with CCPG1 (By similarity)Similarity: Belongs to the MCF2 familySimilarity: Contains 1 CRAL-TRIO domainSimilarity: Contains 1 DH (DBL-homology) domainSimilarity: Contains 1 PH domainSimilarity: Contains 1 SH3 domainSimilarity: Contains 1 spectrin repeat |
Function
for MCF2L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: MCF2L_HUMAN, O15068Function: Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42.Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1,suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomesactivated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42 Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity |
IEA | -- | | GO:0005515 | protein binding |
-- | -- | | GO:0005543 | phospholipid binding |
-- | -- | | GO:0005545 | 1-phosphatidylinositol binding |
IEA | -- |
MCF2L for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for MCF2L:
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Mcf2l):
MCF2L for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MCF2L (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MCF2L (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MCF2L (NM_015078) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MCF2L | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MCF2L |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MCF2L |
|
Pathways & Interactions
for MCF2L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/23 super-pathways (see all 23) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cell death signalling via NRAGE, NRIF and NADE | | | 2 | GPCR Pathway | | | 3 | Signaling by GPCR | | | 4 | G-protein signaling_RhoA regulation pathway | | | 5 | G-protein signaling_RAC1 in cellular process | |
Pathway sources
See GeneCards unified pathways
Show all pathways
4 EMD Millipore Pathways for MCF2L
5/20 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for MCF2L (see all 20)
4  GeneGo (Thomson Reuters) Pathways for MCF2L
3  BioSystems Pathways for MCF2L
5/10 
Reactome Pathways for MCF2L (see all 10)
MCF2L for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MCF2L
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/168 Interacting proteins for MCF2L (O150682, 3 ENSP000003647544) via UniProtKB, MINT, STRING, and/or I2D (see all 168)About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006915 | apoptotic process |
TAS | -- | | GO:0007264 | small GTPase mediated signal transduction |
TAS | -- | | GO:0007266 | Rho protein signal transduction |
IEA | -- | | GO:0035023 | regulation of Rho protein signal transduction |
IEA | -- | | GO:0035556 | intracellular signal transduction |
-- | -- |
MCF2L for ontologies About GeneDecksing
|
Drugs & Compounds
for MCF2L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MCF2L for compounds About GeneDecksing
 Browse Tocris compounds for MCF2L
3 HMDB Compounds for MCF2L About this table
2 Novoseek chemical compound relationships for MCF2L gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| phosphoinositide |
48.2 |
5 |
12637530 (2), 15274927 (1), 11577097 (1) |
| guanine |
37.3 |
1 |
9444953 (1) |
Search CenterWatch for drugs/clinical trials and news about MCF2L
|
Transcripts
for MCF2L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MCF2L gene (2 alternative transcripts): NM_001112732.2 NM_024979.4 Unigene Cluster for MCF2L: MCF.2 cell line derived transforming sequence-like Hs.170422 [show with all ESTs]Unigene Representative Sequence: NM_02497918/36 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 36): ENST00000375608 ENST00000397036 ENST00000442625(uc001vso.3) ENST00000397030(uc001vsq.3 uc001vsu.3 uc010tjr.2 uc001vsr.3 uc010tjs.2)
ENST00000535094 ENST00000421756 ENST00000433807 ENST00000409954 ENST00000375597(uc001vss.4 uc001vst.1)
ENST00000486210 ENST00000397024 ENST00000486806 ENST00000473345 ENST00000480321
ENST00000469558 ENST00000397021 ENST00000494043 ENST00000423251
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MCF2L (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MCF2L (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MCF2L (NM_015078) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MCF2L | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MCF2L |
Additional cDNA sequence: AB116074.1 AB116075.1 AF086413.1 AK094768.1 AK295047.1 AK295670.1 AK307867.1 AK315969.1 BC011853.2 BC020208.1 BC107066.1 BC107067.1 20 DOTS entries: DT.115772 DT.92033375 DT.99957854 DT.95245817 DT.95295746 DT.75197239 DT.40110297 DT.120791719 DT.120791725 DT.120791768 DT.91895987 DT.95285986 DT.120791696 DT.120791740 DT.75195528 DT.92015548 DT.97818395 DT.120791686 DT.87006741 DT.91746518 24/137 AceView cDNA sequences (see all 137): AA339653 AA365066 BM699259 BU681158 BQ684167 AW080046 NM_024979 BC011853 BC020208 CA432698 BM669475 AB116074 BF870252 BF589605 BF870256 BM794518 BU736498 CD671904 BM697869 AB116075 CB154960 BU180155 BF944982 BE327507
GeneLoc Exon Structure
|
Expression
for MCF2L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MCF2L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTCATCCAC
About this image
See MCF2L Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MCF2L
SOURCE GeneReport for Unigene cluster: Hs.170422
SABiosciences Custom PCR Arrays for MCF2L
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MCF2L
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MCF2L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MCF2L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MCF2L | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MCF2L |
Orthologs
for MCF2L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for MCF2L gene from 5/20 species (see all 20) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
MCF2L1 |
MCF.2 cell line derived transforming sequence-like |
70.6(n)
75.77(a) |
|
418748 NM_001252063.1 NP_001238992.1 |
lizard
(Anolis carolinensis) |
Reptilia |
MCF2L6 |
-- |
64(a) |
1 ↔ 1 |
3(105857215-105920008) |
zebrafish
(Danio rerio) |
Actinopterygii |
mcf2l1 |
mcf.2 cell line derived transforming sequence-like |
66.7(n)
66.45(a) |
|
100148439 XM_001922148.3 XP_001922183.3 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG304403 |
guanyl-nucleotide exchange factor |
40(a) |
|
41F4 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
cgef-16 |
CDC-42 Guanine nucleotide Exchange Factor family m... |
19(a) |
1 → many |
X(2785593-2799235) |
ENSEMBL Gene Tree for MCF2L (if available)
TreeFam Gene Tree for MCF2L (if available) |
Paralogs
for MCF2L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MCF2L gene
- KALRN2 ARHGEF252 PLEKHG4B2 MCF2L22 TRIO2 KIAA17552 PLEKHG42 MCF22
- ARHGEF402
7 SIMAP similar genes for MCF2L using alignment to 21 protein entries: MCF2L_HUMAN (see all proteins):MCF2L2 MCF2 KALRN tgat TRIO SESTD1
PREX2
MCF2L for paralogs About GeneDecksing
|
Genomic Variants
for MCF2L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 13 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MCF2L (113548692 - 113754053 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 13 variations for MCF2L
8 CNVs: 3927 4819 66564 49179 31951 9723 23301 71806
5 Indels: 11702 25164 101876 58613 45131 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MCF2L |
|
Disorders
/ Diseases
for MCF2L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MCF2L for disorders About GeneDecksing
OMIM gene information: 609499
OMIM disorders: --
7  diseases for MCF2L: About MalaCardshypoparathyroidism spasticity osteoarthritis breast cancer
carcinoma adenocarcinoma pancreatitis
Human Genome Epidemiology (HuGE) Navigator: MCF2L (3 documents)
Export disorders for MCF2L gene to outside databases
|
Publications
for MCF2L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MCF2L gene, integrated from 9 sources (see all 44):
(articles sorted by number of sources associating them with MCF2L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2, 3 Nagase T.... Ohara O. (1997)
- Role of the Sec14-like domain of Dbl family exchange factors in the regulation of Rho family GTPases in different subcellular sites. (PubMed id 15157669)1, 2, 9 Ueda S.... Satoh T. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange. (PubMed id 11889037)1, 9 Rossman K.L....Sondek J. (2002)
- Genetic contribution to radiographic severity in osteo arthritis of the knee. (PubMed id 22615457)1 Valdes A.M....Doherty M. (2012)
- A variant in MCF2L is associated with osteoarthritis. (PubMed id 21871595)1 Day-Williams A.G....Zeggini E. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Mutation of ARHGAP9 in patients with coronary spastic angina. (PubMed id 19911011)1 Takefuji M....Kaibuchi K. (2010)
|
External Searches for MCF2L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MCF2L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MCF2L gene
(According to HUGE)
About This Section
| |
Specialized Databases showing MCF2L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for MCF2L gene:
Search GeneIP for patents involving MCF2L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MCF2L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | OriGene Antibodies for MCF2L | | OriGene shRNA RFP for MCF2L | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MCF2L | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MCF2L | | | OriGene Protein Over-expression Lysate for MCF2L | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MCF2L | | OriGene 3'-UTR Clone for MCF2L | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MCF2L | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MCF2L | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MCF2L | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MCF2L | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MCF2L | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MCF2L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MCF2L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MCF2L |
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| | | | Search Tocris compounds for MCF2L |
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 | | | MCF2L Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MCF2L |
|  |  |  |  | | | | ThermoFisher Antibodies for MCF2L |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MCF2L |
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