MCEE Gene
protein-coding GIFtS: 59
GCID: GC02M071336
|
|
methylmalonyl CoA epimerase
| |
Aliases
for MCEE gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Methylmalonyl CoA Epimerase1 2 | | GLOD21 2 | | DL-Methylmalonyl-CoA Racemase2 3 | | Glyoxalase Domain Containing 22 | | Methylmalonyl-CoA Epimerase, Mitochondrial2 | | EC 5.1.99.13 |
Export aliases for MCEE gene to outside databasesPrevious GC identifers: GC02M071346 GC02M071547 GC02M071311 GC02M071248 GC02M071190 GC02M071073 |
Summaries
for MCEE gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MCEE:
The product of this gene catalyzes the interconversion of D- and L-methylmalonyl-CoA during the degradation of branchedchain amino acids. odd chain-length fatty acids, and other metabolites. Mutations in this gene result inmethylmalonyl-CoA epimerase deficiency, which is presented as mild to moderate methylmalonic aciduria. (provided byRefSeq, Jul 2008)
|
Genomic Views
for MCEE gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MCEE gene promoter:
HOXA9 HOXA9B Nkx5-1 E47 C/EBPalpha IRF-2 POU2F1 POU2F1a Meis-1a Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MCEE
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MCEE |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p13.3 Ensembl cytogenetic band: 2p13.3 HGNC cytogenetic band: 2p13.3MCEE Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M071336: view genomic region
(about GC identifiers)
Start:
|
71,336,806 bp from pter |
End:
|
71,357,394 bp from pter |
Size:
|
20,589 bases |
Orientation:
|
minus strand |
|
Proteins
for MCEE gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MCEE_HUMAN, Q96PE7 (See
protein sequence)Recommended Name: Methylmalonyl-CoA epimerase, mitochondrial precursor Size: 176 amino acids; 18749 Da
Subcellular location: Mitochondrion (Probable)
1 PDB 3D structure from  and Proteopedia  for MCEE:3RMU (3D)
Secondary accessions: Q53TP1 Q8WW63Explore the universe of human proteins at neXtProt for MCEE: NX_Q96PE7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96PE7
MCEE Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_115990.3
ENSEMBL proteins: ENSP00000391140 ENSP00000244217 ENSP00000437361 ENSP00000441569 Reactome Protein details: Q96PE7
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005739 | mitochondrion |
-- | -- | | GO:0005759 | mitochondrial matrix |
TAS | -- |
MCEE for ontologies About GeneDecksing
MCEE Antibody Products:
Assay Products for MCEE: |
Protein
Domains /
Families
for MCEE gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MCEE for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96PE7ProtoNet protein and cluster: Q96PE7 3 Blocks protein families: IPB004360 Glyoxalase/Bleomycin resistance protein/dioxygenase domain IPB004361 Glyoxalase I IPB011588 Glyoxalase/extradiol ring-cleavage dioxygenase
UniProtKB/Swiss-Prot: MCEE_HUMAN, Q96PE7Similarity: Belongs to the glyoxalase I family |
Function
for MCEE gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MCEE_HUMAN, Q96PE7Catalytic activity: (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoAEnzyme Number (IUBMB): EC 5.1.99.11
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MCEE (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MCEE
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for MCEE | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MCEE |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MCEE |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004493 | methylmalonyl-CoA epimerase activity |
IDA | 11481338 |
MCEE for ontologies About GeneDecksing
|
Pathways & Interactions
for MCEE gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Metabolism | | | 2 | Propionyl-CoA catabolism | | | 3 | Branched-chain amino acid catabolism | | | 4 | Glyoxylate and dicarboxylate metabolism | | | 5 | 2-oxoisovalerate decarboxylation to isobutanoyl-CoA | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3  BioSystems Pathways for MCEE
5 
Reactome Pathways for MCEE
4 
Kegg Pathways (Kegg details for MCEE):
MCEE for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MCEE
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
3 Interacting proteins for MCEE (ENSP000002442174) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006635 | fatty acid beta-oxidation |
TAS | -- | | GO:0019626 | short-chain fatty acid catabolic process |
TAS | -- | | GO:0044255 | cellular lipid metabolic process |
TAS | -- | | GO:0044281 | small molecule metabolic process |
TAS | -- | | GO:0046491 | L-methylmalonyl-CoA metabolic process |
IDA | 11481338 |
MCEE for ontologies About GeneDecksing
|
Drugs & Compounds
for MCEE gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MCEE for compounds About GeneDecksing
 Browse Tocris compounds for MCEE
3 HMDB Compounds for MCEE About this table
7 Novoseek chemical compound relationships for MCEE gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| adenosylcobalamin |
86.1 |
1 |
16843692 (1) |
| methylmalonic acid |
82 |
4 |
17823972 (2) |
| fosfomycin |
72.9 |
2 |
10360943 (1), 11076500 (1) |
| isoleucine |
56.7 |
1 |
11470438 (1) |
| vitamin b12 |
50.4 |
1 |
16697227 (1) |
| valine |
50.2 |
1 |
11470438 (1) |
| methionine |
39.1 |
1 |
11470438 (1) |
Search CenterWatch for drugs/clinical trials and news about MCEE
|
Transcripts
for MCEE gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MCEE gene: NM_032601.3 Unigene Cluster for MCEE: Methylmalonyl CoA epimerase Hs.94949 [show with all ESTs]Unigene Representative Sequence: CB9849525 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000413592 ENST00000244217(uc002shs.2) ENST00000462609 ENST00000494660
ENST00000486135
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MCEE (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MCEE
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MCEE (NM_032601) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MCEE | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MCEE |
Additional cDNA sequence: AF364547.1 BC020825.1 6 DOTS entries: DT.95369217 DT.91713573 DT.40301580 DT.452403 DT.120965828 DT.100027017 24/123 AceView cDNA sequences (see all 123): AA535540 BE219105 AV645652 BU753977 BE218633 AI299838 AW134960 AI927096 CR624276 AI201757 H97986 AI350320 BQ013538 AF364547 CB135530 BF590625 AA376175 CA312248 AV681851 BI962674 AV645970 AW235505 BF594448 BI492716
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for MCEE About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4a | · | 4b |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | - | | - | | - | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MCEE
|
Expression
for MCEE gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MCEE expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAAAGTTCA
About this image
See MCEE Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MCEE
SOURCE GeneReport for Unigene cluster: Hs.94949
SABiosciences Expression via Pathway-Focused PCR Arrays including MCEE:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MCEE
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MCEE |
Orthologs
for MCEE gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for MCEE gene from 6/21 species (see all 21) About this table
ENSEMBL Gene Tree for MCEE (if available)
TreeFam Gene Tree for MCEE (if available) |
Paralogs
for MCEE gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MCEE gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MCEE (71336806 - 71357394 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 18 variations for MCEE
15/17 CNVs (see all 17): 9942 89720 89717 78590 32315 35848 9943 78592 89719 1583 2390 50551 67958 22568 78591
1 Indel: 59001
Human Gene Mutation Database (HGMD): MCEE
Locus Specific Mutation Databases (LSDB): MCEE
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MCEE |
|
Disorders
/ Diseases
for MCEE gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MCEE for disorders About GeneDecksing
OMIM gene information: 608419
OMIM disorders: 251120
UniProtKB/Swiss-Prot: MCEE_HUMAN, Q96PE7
Defects in MCEE are a cause of methylmalonyl-CoA epimerase deficiency (MCEED) [MIM:251120]; also known asmethylmalonyl-CoA racemase deficiency or methylmalonic aciduria type 3. MCEE deficiency is an autosomal recessiveinborn error of amino acid metabolism, involving valine, threonine, isoleucine and methionine. This organic aciduriamay present in the neonatal period with life-threatening metabolic acidosis, hyperammonemia, feeding difficulties,pancytopenia and coma
4  diseases for MCEE: About MalaCardsmethylmalonic acidemia pancytopenia tuberculosis mycobacterium tuberculosis
1 disease from the University of Copenhagen DISEASES database for MCEE:Methylmalonic acidemia 1 Novoseek disease relationship for MCEE gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| methylmalonic aciduria |
87.9 |
6 |
16697227 (2), 16752391 (1), 16843692 (1), 17823972 (1) |
GeneTests: MCEE
Methylmalonic Acidemia
Human Genome Epidemiology (HuGE) Navigator: MCEE (1 document)
Export disorders for MCEE gene to outside databases
|
Publications
for MCEE gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MCEE gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with MCEE) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A homozygous nonsense mutation in the methylmalonyl-CoA epimerase gene (MCEE) results in mild methylmalonic aciduria. (PubMed id 16752391)1, 2, 3, 9 Bikker H.... Duran M. (2006)
- Homozygous nonsense mutation in the MCEE gene and siRNA suppression of methylmalonyl-CoA epimerase expression: a novel cause of mild methylmalonic aciduria. (PubMed id 16697227)1, 3, 9 Dobson C.M....Gravel R.A. (2006)
- Propionyl-CoA and adenosylcobalamin metabolism in Cae norhabditis elegans: evidence for a role of methylmalonyl-CoA epimerase in inte rmediary metabolism. (PubMed id 16843692)1, 3, 9 Chandler R.J....Venditti C.P. (2006)
- Identification of the human methylmalonyl-CoA racemase gene based on the analysis of prokaryotic gene arrangements. Implications for decoding the human genome. (PubMed id 11481338)1, 2, 9 Bobik T.A. and Rasche M.E. (2001)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Atypical methylmalonic aciduria: frequency of mutations in the methylmalonyl CoA epimerase gene (MCEE). (PubMed id 17823972)1, 9 Gradinger A.B....Rosenblatt D.S. (2007)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for MCEE gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MCEE gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MCEE gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MCEE gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MCEE | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MCEE gene:
Search GeneIP for patents involving MCEE
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MCEE gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MCEE | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MCEE | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MCEE | | | OriGene Protein Over-expression Lysate for MCEE | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MCEE | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MCEE | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MCEE | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MCEE | | OriGene Custom Protein Services for MCEE | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MCEE | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MCEE | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MCEE | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MCEE | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MCEE | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MCEE |
| |
 |  |  |  | |
| | | | Search Tocris compounds for MCEE |
| |  |  |  |  | | | | | | Recombinant Protein for MCEE |
|
 |
 |
 |
 | | | MCEE Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MCEE |
|  |  |  | | | | ThermoFisher Antibodies for MCEE |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MCEE |
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