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MCC Gene

protein-coding GIFtS: 60

GC05M112388

mutated in colorectal cancers
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
DKFZp762O1615 ^²
FLJ38893 ^²
FLJ46755 ^²
MCC1 ^²

Descriptions
Protein MCC ^³
mutated in colorectal cancers ^²

External Ids
HGNC: 6935¹
Entrez Gene: 4163²
UniProtKB: P23508³
Ensembl: ENSG00000171444⁷

Search outside databases for aliases for MCC gene

Previous GC identifers: GC05M111957 GC05M112808 GC05M112392 GC05M112437 GC05M112434

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for MCC:

This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate

cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated

with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits

entry into S phase. Multiple transcript variants encoding different isoforms have been found for

this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: CRCM_HUMAN, P23508

Function: Candidate for the putative colorectal tumor suppressor gene located at 5q21

Gene Wiki entry for MCC

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the MCC gene

Entrez Gene cytogenetic band: 5q21 Ensembl cytogenetic band: 5q22.2 HGNC cytogenetic band: 5q21-q22

MCC Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05M112388: (about GC identifiers)

Start:	112,385,695 bp from pter
End:	112,852,426 bp from pter
Size:	466,732 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000005.8 NT_034772.5

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: CRCM_HUMAN, P23508 (See protein sequence)

Recommended Name: Colorectal mutant cancer protein

Size: 829 amino acids; 93055 Da

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_001078846.1 NP_002378.1

ENSEMBL proteins:

ENSP00000305617 ENSP00000386227

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (MCC)
	Human Recombinant Proteins from Abnova (MCC)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

Antibodies for MCC:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for MCC
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (MCC), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (MCC)
	Novus Biologicals Antibodies for MCC

Assays for MCC:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry P23508

ProtoNet protein and cluster: P23508

UniProtKB/Swiss-Prot: CRCM_HUMAN, P23508

Similarity: Belongs to the MCC family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MCC)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MCC)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_002387

Applied Biosystems Silencer® siRNAs for MCC

Sigma-Aldrich siRNA for MCC

Sigma-Aldrich shRNA Panels and shRNA for MCC

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for MCC
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001085377
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001085377
untagged cDNA clones in CMV expression vector (see all 2): NM_001085377

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001085377

UniProtKB/Swiss-Prot: CRCM_HUMAN, P23508

Function: Candidate for the putative colorectal tumor suppressor gene located at 5q21

Genatlas biochemistry entry for MCC:

mutated in colorectal cancer (see TSG5A)

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004872	receptor activity	TAS	1848370
GO:0005515	protein binding	IPI	14743216 17353931

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for MCC

5/35 Interacting proteins for MCC (P23508^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 35 )
Interactant Interaction Details
GeneCard External ID(s)
NFKBIB Q15653¹^,² EBI-307531, EBI-352889 MINT-47859 EBI-307531, EBI-352889 MINT-47859
CBR1 P16152¹ EBI-307531, EBI-351348
CCNA1 P78396¹ EBI-307531, EBI-375065
CLTC Q00610¹ EBI-307531, EBI-354967
CSNK1D P48730¹ EBI-307531, EBI-751621
About this table
2 Gene Ontology (GO) biological process terms (links to tree view):
GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction TAS 1848370
GO:0045786 negative regulation of cell cycle IEA --
About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for MCC

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MCC)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MCC)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_002387

Sigma-Aldrich siRNA for MCC

Sigma-Aldrich shRNA Panels and shRNA for MCC

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001085377 NM_002387

REFSEQ mRNAs for MCC gene (2 alternative transcripts):

NM_001085377.1 NM_002387.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001085377 NM_002387

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001085377
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001085377
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_001085377

Additional cDNA sequence:

AK096212.1 AK128596.1 AK300259.1 AL359558.1 BC009279.2 BC018919.2 BC043431.2 BX537952.1

BX647710.1 CR749713.1 M62397.1

12 DOTS entries:

DT.441438 DT.439205 DT.206787 DT.99936084 DT.437378 DT.101982227 DT.120847212 DT.40210745

DT.92419764 DT.92426124 DT.120847111 DT.100800143

24/155 AceView cDNA sequences (see all 155 ):

CA337225 AV661084 BM313537 CF890841 CB305455 CD515997 AW169982 AA018666

BM665160 BM666451 BQ188031 AK096212 BX445883 N29051 BQ423407 BM695282

AL706228 AI031639 AK128596 N85260 BV202211 BU189477 BC009279 AV645733

highest scoring ESTs for MCC:

AA587459 BC009279 BC018919 BF203829 BF308292 BX647710 M62397 AA053723 AA317497 AI025592

Unigene Cluster for MCC:

Mutated in colorectal cancers

Hs.593171 [show with all ESTs]

Unigene Representative Sequence: NM_001085377

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for MCC

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7a	·	7b	^	8	^	9	^	10	^	11a	·	11b	^	12	^	13	^	14	^	15	^	16	^	17	^	18a	·	18b
SP1:																	-
SP2:					-												-
SP3:					-		-										-
SP4:

About this scheme

ECgene alternative splicing isoforms for MCC

2 Ensembl transcripts including schematic representations:

ENST00000302475 ENST00000408903

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

MCC expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for MCC

¹ / ² / ³

12 probe-sets matching MCC gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
1832_at²^{, 3}	U95-A	1	1.00	1.00	0.02	0.69	M62397	0.80	1.00	0.91	1
74146_at²^{, 3}	U95-D	1	1.00	1.00	0.78	1.11	AA587459	0.80	1.00	0.91	1
49504_r_at²^{, 3}	U95-B	1	1.00	1.00	0.98	0.95	AI379607	0.60	1.00	0.82	1
73437_at²^{, 3}	U95-E	1	1.00	1.00	0.92	1.31	AI025592	0.60	1.00	0.82	1
49502_i_at²^{, 3}	U95-B	1	1.00	1.00	0.95	1.20	AI379607	0.60	1.00	0.82	1
35561_at²^{, 3}	U95-A	1	0.88	1.00	0.40	0.15	M62397	0.80	1.00	0.91	1
49506_at²^{, 3}	U95-B	1	0.81	1.00	0.88	1.00	AA053723	0.60	1.00	0.82	1
52730_at*²^{, 3}	U95-C	1	--	--	-0.35	0.78	N26089	0.20	1.00	0.72	1
206132_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_002387	0.60	1.00	0.82	1
226225_at²	U133-B	1	1.00	1.00	--	--	--	--	--	--	--
206132_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
226225_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks MCC for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGACTAAGTT

SOURCE GeneReport for Unigene cluster: Hs.593171
Expression variation in blood from EXPOLDB for MCC
UniProtKB/Swiss-Prot: CRCM_HUMAN, P23508
Tissue specificity: Expressed in a variety of tissues

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for MCC gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	MCC¹	--	mutated in colorectal cancers	91.48(n) 97.9(a)	611208 XM_848846.1 XP_853939.1
chimpanzee (Pan troglodytes)	MCC¹	--	mutated in colorectal cancers	99.15(n) 99.61(a)	462002 XM_517879.2 XP_517879.2
cow (Bos taurus)	MCC¹	--	mutated in colorectal cancers	90.23(n) 95.49(a)	784835 XM_001253034.1 XP_001253035.1
rat (Rattus norvegicus)	RGD1561988¹	--	similar to Colorectal mutant cancer protein (MCC protein)	87.19(n) 94.21(a)	307449 XM_225962.4 XP_225962.4
mouse (Mus musculus)	Mcc⁵	18 (21.00 cM)	mutated in colorectal cancers	--	C86509

About this table Species with no ortholog for MCC

ENSEMBL Gene Tree for MCC

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for MCC gene

USHBP1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/2985 NCBI SNPs in MCC are shown (see all 2985 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 717)

AB	SNP ID	Valid	Chr 5 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs1422222^1,2	A,C,F,H,O	112387978(-)	`GTTGCG/AAGTGC`	2	--	ut3¹		16	MN EA NA EU WA	2714
	rs2112452^1,2	A,C,F,H,O	112386392(-)	`GTCATT/CCATCT`	2	--	ut3¹ ese³		7	EU EA WA NA	554
	rs1549181^1,2	A,C,F,H,O	112390739(-)	`TGGGGT/CGACTG`	2	--	ut3¹ ese³		12	MN EU EA WA NA	1164
--	rs348939^1,2	A,C,F,H,O	112852636(-)	`AGACTG/CTTCCC`	1	--	ng3¹		7	EU EA WA NA	562
	rs7033^1,2	A,C,F,H	112385821(-)	`TGTAAA/GATAGC`	2	--	ut3¹		11	EU EA WA NA	980
--	rs348938^1,2	A,C,F,H	112852931(-)	`taacaT/Gttgtt`	1	--	ng3¹		8	EU EA WA	840
--	rs348937^1,2	A,C,F,H	112853576(-)	`gctctA/Gggggt`	1	--	ng3¹		8	EU EA WA	840
	rs9122^1,2	A,C,F,H	112386030(-)	`TATACA/GCTTGA`	2	--	ut3¹ ese³		14	MN NS NA EU EA WA	1026
	rs3209874^1,2	C,F,H,O	112386789(-)	`AACTTG/ATGGCC`	2	--	ut3¹ ese³		12	NS NA EU EA WA	660
	rs3185733^1,2	C,F,H	112386919(-)	`TCTTAG/TAGAGT`	2	--	ut3¹		5	MN EU EA WA	582

About this table

HapMap Linkage Disequilibrium images for MCC (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 159350

UniProtKB/Swiss-Prot: CRCM_HUMAN, P23508

Is probably involved in early stages of colorectal neoplasia in both sporadic and familial

tumors

9 Novoseek disease relationships for MCC gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
familial adenomatous polyposis	76.79	4	1565631 (2), 1325652 (2)
colorectal tumors	75.96	7	1848370 (2), 8626604 (2), 1651562 (1), 1682292 (1)
colorectal cancer	53.37	5	1848370 (1), 1668888 (1), 1682292 (1), 1339098 (1) (see all 5)
colorectal carcinoma	53.15	3	1682292 (2), 1325652 (1)
nsclc	45.69	2	7812947 (1)
colon cancer	34.59	4	1565631 (2), 1314630 (1), 11311560 (1)
tumors	27.00	10	11311560 (2), 7796415 (1), 8226275 (1), 7812947 (1) (see all 8)
cancer lung	23.18	2	1565631 (1), 1348017 (1)
cancer	4.80	2	1565631 (2)

About this table

Tumor Gene Database: MCC
Breast Cancer Gene Database: MCC

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/35 PubMed articles for MCC gene (see all 35 ):

Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. (PubMed id 1848370)^{1, 2, 3, 4} Kinzler K.W.... Nakamura Y. (1991)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. (PubMed id 1651563)^{3, 4} Nishisho I....Hedge P. (1991)
MCC, a cytoplasmic protein that blocks cell cycle progression from the G0/G1 to S phase. (PubMed id 8626604)^{1, 3} Matsumine A....Akiyama T. (1996)
Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses beta-catenin-dependent transcription. (PubMed id 18591935)³ Fukuyama R....Sizemore N. (2008)
Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)³ Ewing R.M....Figeys D. (2007)
The LIFEdb database in 2006. (PubMed id 16381901)³ Mehrle A....Wiemann S. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)³ Ota T....Sugano S. (2004)
A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. (PubMed id 14743216)³ Bouwmeester T....Superti-Furga G. (2004)
From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)³ Wiemann S....Poustka A. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 4163	HGNC: 6935	AceView: MCC	Ensembl:ENSG00000171444	euGenes: HUgn4163
ECgene: MCC	H-InvDB: MCC

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for MCC	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for MCC
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for MCC:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for MCC-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for MCC		Antibodies for MCC
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for MCC		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (MCC)
	Antibodies (MCC)
	Chimera RNAi (MCC)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (MCC)
	Antibodies (MCC)

Search OriGene for MCC

Search Tocris compounds for MCC

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for MCC

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
MCC Gene at Home site.
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MCC Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for MCC

Summaries
for MCC

Genomic Location
for MCC

Proteins
for MCC

Protein Domains/
Families
for MCC

Gene Function
for MCC

Pathways & Interactions
for MCC

Drugs & Compounds
for MCC

Transcripts
for MCC

Expression
for MCC

Orthologs
for MCC

Paralogs
for MCC

SNPs/Variants
for MCC

Disorders & Mutations
for MCC

Medical News
for MCC

Publications
for MCC

Search for MCC

Genome Databases showing MCC

Other Databases showing MCC

Specialized Databases showing MCC

Licensable Technologies
for MCC

Services
for MCC

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

MCC Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor MCC

Summariesfor MCC

Genomic Locationfor MCC

Proteinsfor MCC

Protein Domains/Familiesfor MCC

Gene Functionfor MCC

Pathways & Interactionsfor MCC

Drugs & Compoundsfor MCC

Transcriptsfor MCC

Expression for MCC

Orthologsfor MCC

Paralogsfor MCC

SNPs/Variantsfor MCC

Disorders & Mutationsfor MCC

Medical Newsfor MCC

Publicationsfor MCC

Search for MCC

Genome Databases showing MCC

Other Databases showing MCC

Specialized Databases showing MCC

Licensable Technologiesfor MCC

Servicesfor MCC

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for MCC

Summaries
for MCC

Genomic Location
for MCC

Proteins
for MCC

Protein Domains/
Families
for MCC

Gene Function
for MCC

Pathways & Interactions
for MCC

Drugs & Compounds
for MCC

Transcripts
for MCC

Expression
for MCC

Orthologs
for MCC

Paralogs
for MCC

SNPs/Variants
for MCC

Disorders & Mutations
for MCC

Medical News
for MCC

Publications
for MCC

Licensable Technologies
for MCC

Services
for MCC