Aliases for MCAT Gene
External Ids for MCAT Gene
Previous GeneCards Identifiers for MCAT Gene
The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2012]
GeneCards Summary for MCAT Gene
MCAT (Malonyl-CoA-Acyl Carrier Protein Transacylase) is a Protein Coding gene. Diseases associated with MCAT include Middle Ear Disease. Among its related pathways are Mitochondrial Fatty Acid Beta-Oxidation and Fatty acid biosynthesis (KEGG). GO annotations related to this gene include poly(A) RNA binding and [acyl-carrier-protein] S-malonyltransferase activity.
UniProtKB/Swiss-Prot for MCAT Gene
Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acids in mitochondrias.