MC3R Gene
protein-coding GIFtS: 61
GCID: GC20P054823
|
|
melanocortin 3 receptor
| |
Aliases
for MC3R gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Melanocortin 3 Receptor1 2 | | OB202 | | MC31 2 | | OQTL2 | | MC3-R2 3 | | Melanocortin Receptor 32 | | BMIQ92 5 | | Obesity Quantitative Trait Locus2 |
Export aliases for MC3R gene to outside databasesPrevious GC identifers: GC20P054552 GC20P055462 GC20P055509 GC20P054257 GC20P051605 |
Summaries
for MC3R gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MC3R:
This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone thatis expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locusfor benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake,suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associatedwith a susceptibility to obesity in humans. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: MC3R_HUMAN, P41968Function: Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activateadenylate cyclase
 summary
for MC3R: Melanocortin receptors are activated by members of the melanocortin family: alpha-, beta- and
gamma-melanocyte stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). Endogenous antagonists
include agouti and agouti-related protein (AgRP). The melanocortin receptors are G-protein-coupled and 5
subtypes exist, MC1-5. The melanocortins are involved in a wide range of physiological functions, including
pigmentation, energy homeostasis, inflammation, immunomodulation, steroidogenesis and temperature control.
Gene Wiki entry for MC3R (Melanocortin 3 receptor)
|
Genomic Views
for MC3R gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011362.10
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MC3R gene promoter:
AML1a NRSF form 1 NRSF form 2 Arnt C/EBPalpha CHOP-10 AREB6 POU2F1 POU2F1a ATF
Other transcription factors
Search SABiosciences Chromatin IP Primers for MC3R
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MC3R |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20q13.2-q13.3 Ensembl cytogenetic band: 20q13.2 HGNC cytogenetic band: 20q13.2-q13.3MC3R Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20P054823: view genomic region
(about GC identifiers)
Start:
|
54,823,788 bp from pter |
End:
|
54,824,871 bp from pter |
Size:
|
1,084 bases |
Orientation:
|
plus strand |
|
Proteins
for MC3R gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MC3R_HUMAN, P41968 (See
protein sequence)Recommended Name: Melanocortin receptor 3 Size: 323 amino acids; 36043 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence caution: Sequence=AAC13541.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;Sequence=AAH69105.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=AAH69599.1;Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=AAH96702.1; Type=Erroneous initiation;Note=Translation N-terminally shortened; Sequence=AAH96737.1; Type=Erroneous initiation; Note=Translation N-terminallyshortened; Sequence=AAH98169.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;Sequence=AAH98351.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=AAO72726.1;Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q4KN27 Q9H517Explore the universe of human proteins at neXtProt for MC3R: NX_P41968
MC3R Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_063941.3
ENSEMBL proteins: ENSP00000243911 Reactome Protein details: P41968
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
MC3R for ontologies About GeneDecksing
MC3R Antibody Products:
Assay Products for MC3R: |
Protein
Domains /
Families
for MC3R gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MC3R for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P41968ProtoNet protein and cluster: P41968 3 Blocks protein families: IPB001671 Melanocortin receptor family signature IPB001908 Melanocortin receptor signature IPB002122 Melanocortin 3 receptor signature
UniProtKB/Swiss-Prot: MC3R_HUMAN, P41968Similarity: Belongs to the G-protein coupled receptor 1 family |
Function
for MC3R gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MC3R_HUMAN, P41968Function: Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activateadenylate cyclase Genatlas biochemistry entry for MC3R:melanocortin receptor 3,expressed in brain,placenta and intestinal tissues,G protein coupled receptor superfamily
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MC3R (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MC3R
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MC3R (NM_019888) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MC3R | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MC3R |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MC3R |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
MC3R for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for MC3R:
Animal Models:
Mouse knock-outs for MC3R: Mc3rtm1Cone Mc3rtm1Lvp Mc3rtm1Lex
7 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Mc3r):
MC3R for phenotypes About GeneDecksing
|
Pathways & Interactions
for MC3R gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Class A/1 (Rhodopsin-like receptors) | | | 2 | Signaling by GPCR | | | 3 | Adenylate cyclase-activating neuropeptides | | | 4 | Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q | | | 5 | G beta:gamma signalling through PLC beta | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for MC3R
2  BioSystems Pathways for MC3R
5/7 
Reactome Pathways for MC3R (see all 7)
1 
Kegg Pathway (Kegg details for MC3R):
MC3R for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MC3R
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/68 Interacting proteins for MC3R (P419683 ENSP000002439114) via UniProtKB, MINT, STRING, and/or I2D (see all 68)About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0002027 | regulation of heart rate |
IEA | -- | | GO:0007187 | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
TAS | 8175743 | | GO:0007188 | adenylate cyclase-modulating G-protein coupled receptor signaling pathway |
IEA | -- | | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway |
TAS | 8175743 | | GO:0008217 | regulation of blood pressure |
IEA | -- |
MC3R for ontologies About GeneDecksing
|
Drugs & Compounds
for MC3R gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MC3R for compounds About GeneDecksing
Compounds for MC3R available from Tocris Bioscience About this table
10/14 Novoseek chemical compound relationships for MC3R gene (see all 14) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| shu 9119 |
92.2 |
10 |
12851307 (1), 10657491 (1), 12505663 (1), 9751529 (1) (see all 8) |
| alpha msh |
78.9 |
4 |
16177130 (1), 9751529 (1), 11511108 (1) |
| org-2766 |
75 |
1 |
7808440 (1) |
| acth |
68 |
20 |
12384937 (3), 19743876 (2), 8584883 (1), 11892914 (1) (see all 14) |
| acth 4-10 |
67.3 |
1 |
9213373 (1) |
| cyclic amp |
20.9 |
1 |
10051117 (1) |
| corticosterone |
15.9 |
1 |
9605554 (1) |
| proline |
6.8 |
1 |
10405347 (1) |
| glucose |
0.188 |
3 |
17192297 (1), 12142547 (1), 11397906 (1) |
| lipid |
0 |
2 |
17192297 (1), 15202783 (1) |
Search CenterWatch for drugs/clinical trials and news about MC3R
|
Transcripts
for MC3R gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MC3R gene: NM_019888.3 Unigene Cluster for MC3R: Melanocortin 3 receptor Hs.248018 [show with all ESTs]Unigene Representative Sequence: BC0691051 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000243911(uc002xxb.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MC3R (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MC3R
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MC3R (NM_019888) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MC3R | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MC3R |
Additional cDNA sequence: AY227893.1 BC069105.1 BC069591.1 BC069599.1 BC096702.1 BC096737.1 BC098169.1 BC098351.1 1 DOTS entry: DT.102819981 5 AceView cDNA sequences: BC069105 BC069599 BC069591 NM_019888 AY227893
GeneLoc Exon Structure
|
Expression
for MC3R gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MC3R expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AACTTGGGAT
About this image
See MC3R Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MC3R
SOURCE GeneReport for Unigene cluster: Hs.248018
UniProtKB/Swiss-Prot: MC3R_HUMAN, P41968Tissue specificity: Brain, placental, and gut tissues
SABiosciences Expression via Pathway-Focused PCR Arrays including MC3R:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MC3R
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MC3R | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MC3R | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MC3R | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MC3R |
Orthologs
for MC3R gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for MC3R gene from 3/11 species (see all 11) About this table
ENSEMBL Gene Tree for MC3R (if available)
TreeFam Gene Tree for MC3R (if available) |
Paralogs
for MC3R gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MC3R gene
- CNR12 GPR122 ENSG000002675342 LPAR22 CNR22 S1PR12 S1PR32 MC1R2
- LPAR12 MC5R2 MC2R2 GPR32 MC4R2 S1PR42 GPR62 LPAR32
- S1PR52
6 SIMAP similar genes for MC3R using alignment to 1 protein entry: MC3R_HUMAN:MC4R LOC441453 MC5R MC2R MC1R LPAR1
MC3R for paralogs About GeneDecksing
|
Genomic Variants
for MC3R gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
UniProtKB/Swiss-Prot: MC3R_HUMAN, P41968Polymorphism: Genetic variations in MC3R define the body mass index quantitative trait locus 9 (BMIQ9) [MIM:602025].Variance in body mass index is a susceptibility factor for obesity
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MC3R (54823788 - 54824871 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MC3R: --
Human Gene Mutation Database (HGMD): MC3R
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MC3R |
|
Disorders
/ Diseases
for MC3R gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MC3R for disorders About GeneDecksing
OMIM gene information: 155540
OMIM disorders: 602025 607948
20/25  diseases for MC3R (see all 25): About MalaCardsobesity mycobacterium tuberculosis, protection against tuberculosis, protection against tricuspid valve insufficiency
mycobacterium tuberculosis anorexia nervosa type 2 diabetes mellitus autism spectrum disorder
sleep apnea insulin resistance diabetes mellitus morbid obesity
atopic dermatitis apnea mucoepidermoid carcinoma cushing's syndrome
hyperinsulinism tuberculosis obesity, association with dermatitis
2 diseases from the University of Copenhagen DISEASES database for MC3R:Morbid obesity DOID:13189 8 Novoseek disease relationships for MC3R gene About this table
Genetic Association Database (GAD): MC3R
Human Genome Epidemiology (HuGE) Navigator: MC3R (30 documents)
Export disorders for MC3R gene to outside databases
|
Publications
for MC3R gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MC3R gene, integrated from 9 sources (see all 191):
(articles sorted by number of sources associating them with MC3R) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel melanocortin 3 receptor gene (MC3R) mutation associated with severe obesity. (PubMed id 11889220)1, 2, 4, 9 Lee Y.-S.... Loke K.-Y. (2002)
- Molecular cloning of a novel melanocortin receptor. (PubMed id 8463333)1, 2, 3 Gantz I.... Yamada T. (1993)
- Sporadic mutations in melanocortin receptor 3 in morbid obese individuals. (PubMed id 18231126)1, 2, 9 Mencarelli M.... Di Blasio A.M. (2008)
- Co-occurrence of two partially inactivating polymorphisms of MC3R is associated with pediatric-onset obesity. (PubMed id 16123355)1, 4, 9 Feng N....Yanovski J.A. (2005)
- Melanocortin-3-receptor gene variants in morbid obesity. (PubMed id 12532156)1, 4, 9 Schalin-Jantti C....Kontula K. (2003)
- Functional characterization of melanocortin-3 receptor variants identify a loss-of-function mutation involving an amino acid critical for G protein-coupled receptor activation. (PubMed id 15292330)1, 2, 9 Tao Y.-X. and Segaloff D.L. (2004)
- Naturally occurring mutations in the melanocortin receptor 3 gene are not associated with type 2 diabetes mellitus in French Caucasians. (PubMed id 11397906)1, 4, 9 Hani E.H....Froguel P. (2001)
- The Val81 missense mutation of the melanocortin 3 receptor gene, but not the 1908c/T nucleotide polymorphism in lamin A/C gene, is associated with hyperleptinemia and hyperinsulinemia in obese Greek caucasians. (PubMed id 15636422)1, 4, 9 Yiannakouris N....Mantzoros C.S. (2004)
- A +2138InsCAGACC polymorphism of the melanocortin receptor 3 gene is associated in human with fat level and partitioning in interaction with body corpulence. (PubMed id 12142547)1, 4, 9 Boucher N....Chagnon Y.C. (2002)
- Melanocortin-4 receptor gene and physical activity in the Quebec Family Study. (PubMed id 15597110)1, 4, 9 Loos R.J....Bouchard C. (2005)
|
External Searches for MC3R gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MC3R gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MC3R gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MC3R gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MC3R | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MC3R gene:
Search GeneIP for patents involving MC3R
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MC3R gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for MC3R | | OriGene shRNA RFP for MC3R | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MC3R | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MC3R | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MC3R | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MC3R | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MC3R | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MC3R | | OriGene Custom Protein Services for MC3R | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MC3R | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MC3R | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MC3R | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MC3R | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MC3R | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MC3R |
| |
 |  |  |  | |
| | | | Tocris compounds for MC3R |
| |  |  |  |  | | | | |
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 |
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 | | | MC3R Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MC3R |
|  |  |  | | | | ThermoFisher Antibodies for MC3R |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MC3R |
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