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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MBOAT4 Gene

protein-coding   GIFtS: 40
GCID: GC08M029989

Membrane Bound O-Acyltransferase Domain Containing 4

(Previous name: O-acyltransferase (membrane bound) domain containing 4)
(Previous symbol: OACT4)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Membrane Bound O-Acyltransferase Domain Containing 41 2     Ghrelin O-Acyltransferase1 2
OACT41 2 3     Membrane-Bound O-Acyltransferase Domain-Containing Protein 42 3
GOAT2 3 5     O-Acyltransferase Domain-Containing Protein 42 3
O-Acyltransferase (Membrane Bound) Domain Containing 41 2     EC 2.3.1.-3

External Ids:    HGNC: 323111   Entrez Gene: 6193732   Ensembl: ENSG000001776697   OMIM: 6119405   UniProtKB: Q96T533   

Export aliases for MBOAT4 gene to outside databases

Previous GC identifers: GC08M030108 GC08M028533


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for MBOAT4 Gene: 
MBOAT4 (membrane bound O-acyltransferase domain containing 4) is a protein-coding gene. Diseases associated with MBOAT4 include ileus, and gastroparesis, and among its related super-pathways are Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) and Insulin Processing. GO annotations related to this gene include serine O-acyltransferase activity. An important paralog of this gene is LPCAT3.

UniProtKB/Swiss-Prot: MBOA4_HUMAN, Q96T53
Function: Mediates the octanoylation of ghrelin at 'Ser-3'. Can use a variety of fatty acids as substrates
including octanoic acid, decanoic acid and tetradecanoic acid




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.2  NT_167187.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MBOAT4 gene promoter:
         c-Fos   AP-1   JunB   Lmo2   Fra-1   FosB   GATA-6   FOXC1   JunD   c-Jun   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for MBOAT4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MBOAT4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p12   Ensembl cytogenetic band:  8p12   HGNC cytogenetic band: 8p12

MBOAT4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MBOAT4 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M029989:  view genomic region     (about GC identifiers)

Start:
29,989,187 bp from pter      End:
30,002,202 bp from pter
Size:
13,016 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MBOA4_HUMAN, Q96T53 (See protein sequence)
Recommended Name: Ghrelin O-acyltransferase  
Size: 435 amino acids; 49716 Da
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity)
Secondary accessions: B1Q003
Alternative splicing: 2 isoforms:  Q96T53-1   Q96T53-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MBOAT4: NX_Q96T53

Explore proteomics data for MBOAT4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96T53

  • MBOAT4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MBOAT4 Protein Expression
    REFSEQ proteins: NP_001094386.1  
    ENSEMBL proteins: 
     ENSP00000314196  
    Reactome Protein details: Q96T53
    Human Recombinant Protein Products for MBOAT4: 
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    Novus Biologicals MBOAT4 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane TAS--
    GO:0030176integral to endoplasmic reticulum membrane ISS--

    MBOAT4 for ontologies           About GeneDecksing



    MBOAT4 Antibody Products: 
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    GenScript Custom Assay Services for MBOAT4
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR004299 MBOAT_fam

    Graphical View of Domain Structure for InterPro Entry Q96T53

    ProtoNet protein and cluster: Q96T53

    UniProtKB/Swiss-Prot: MBOA4_HUMAN, Q96T53
    Similarity: Belongs to the membrane-bound acyltransferase family


    MBOAT4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MBOA4_HUMAN, Q96T53
    Function: Mediates the octanoylation of ghrelin at 'Ser-3'. Can use a variety of fatty acids as substrates
    including octanoic acid, decanoic acid and tetradecanoic acid

         Enzyme Number (IUBMB): EC 2.3.1.-1

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016412serine O-acyltransferase activity IDA18443287
         
    MBOAT4 for ontologies           About GeneDecksing


    Phenotypes:
         5 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Mboat4):
     adipose tissue  behavior/neurological  growth/size  homeostasis/metabolism  mortality/aging 

    MBOAT4 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Mboat4tm1Jagu for MBOAT4

       inGenious Targeting Laboratory - Custom generated mouse model solutions for MBOAT4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MBOAT4

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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MBOAT4 

    miRNA
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    Inhib. RNA
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    Clone
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for MBOAT4 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
    Synthesis, Secretion, and Deacylation of Ghrelin0.46
    2Insulin Processing
    Peptide hormone metabolism0.39
    3Asparagine N-linked glycosylation
    Metabolism of proteins0.35

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for MBOAT4
        Synthesis, Secretion, and Deacylation of Ghrelin
    Metabolism of proteins
    Peptide hormone metabolism



    MBOAT4 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MBOAT4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/6 Interacting proteins for MBOAT4 (ENSP000003141964) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PCSK1ENSP000003080244STRING: ENSP00000308024
    SEC11AENSP000002682204STRING: ENSP00000268220
    SEC11CENSP000002997144STRING: ENSP00000299714
    SPCS1ENSP000002330254STRING: ENSP00000233025
    SPCS2ENSP000002636724STRING: ENSP00000263672
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0018191peptidyl-serine octanoylation IDA18443287
    GO:0044267cellular protein metabolic process TAS--

    MBOAT4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MBOAT4 (MBOA4)

    Search CenterWatch for drugs/clinical trials and news about MBOAT4 / MBOA4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MBOAT4 gene: 
    NM_001100916.1  

    Unigene Cluster for MBOAT4:

    Membrane bound O-acyltransferase domain containing 4
    Hs.627194  [show with all ESTs]
    Unigene Representative Sequence: NM_001100916
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000320542(uc010lvg.3)
    miRNA
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    hsa-miR-3688-3p hsa-miR-3153
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Clone
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    Additional mRNA sequence: EU518495.2 

    1 DOTS entry:

    DT.120629872 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MBOAT4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    MBOAT4 Expression
    About this image


    See MBOAT4 Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.627194

    UniProtKB/Swiss-Prot: MBOA4_HUMAN, Q96T53
    Tissue specificity: Expressed predominantly in stomach with moderate levels in pancreas and relatively low levels
    in most other tissues

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MBOAT4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for MBOAT4 gene from 7/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mboat41 , 5 membrane bound O-acyltransferase domain containing more1, 5 80.84(n)1
    78.62(a)1
      8 (20.90 cM)5
    2341551  NM_001126314.21  NP_001119786.11 
     341150305 
    chicken
    (Gallus gallus)
    Aves MBOAT41 membrane bound O-acyltransferase domain containing more 59.9(n)
    54.52(a)
      428757  NM_001199289.1  NP_001186218.1 
    lizard
    (Anolis carolinensis)
    Reptilia MBOAT46
    Uncharacterized protein
    55(a)
    1 ↔ 1
    GL343257.1(768414-776511)
    zebrafish
    (Danio rerio)
    Actinopterygii mboat41 membrane bound O-acyltransferase domain containing more 50.5(n)
    39.5(a)
      795709  NM_001122944.1  NP_001116416.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta oys6
    oysgedart
    11(a)
    1 → many
    2R(5923268-5936123)
    worm
    (Caenorhabditis elegans)
    Secernentea mboa-56
    mboa-46
    (see all 3)
    Protein MBOA-4, isoform c
    (see all 3)
    14(a)
    13(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    IV(17239941-17241533)
    IV(11157149-11159492)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ALE16
    Broad-specificity lysophospholipid acyltransferase...
    11(a)
    1 → many
    XV(659815-661674)


    ENSEMBL Gene Tree for MBOAT4 (if available)
    TreeFam Gene Tree for MBOAT4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MBOAT4 gene
    LPCAT32  MBOAT12  MBOAT22  MBOAT72  

    MBOAT4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/259 SNPs in MBOAT4 are shown (see all 259)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0300694
    ----see VAR_0300692 G E mis40--------
    rs735767251,2
    C,F--29995761(+) AATTAC/TTCTTT 1 -- int11Minor allele frequency- T:0.50WA 2
    rs1413523311,2
    --29995821(+) CTGGGC/TGGTTA 1 -- int10--------
    rs1893699441,2
    --29995828(+) GTTACA/GCTAAC 1 -- int10--------
    rs1912616031,2
    --29995867(+) GTTAGA/CCCCAT 1 -- int10--------
    rs1451345531,2
    C--29995905(+) GAAAGA/CGGTAA 1 -- int10--------
    rs1159765261,2
    F--29995916(+) AATGAC/TTTGCT 1 -- int11Minor allele frequency- T:0.01WA 118
    rs1173684971,2
    C,F--29995918(+) TGACTT/CGCTCA 1 -- int11Minor allele frequency- C:0.02NA 120
    rs1485039051,2
    C--29996007(+) CAAAC-/TGTA  
            
    TGTAG
    1 -- int10--------
    rs1473974451,2
    F--29996058(-) AGCCTC/TCTTCT 2 P S mis11Minor allele frequency- T:0.00NS 24056

    HapMap Linkage Disequilibrium report for MBOAT4 (29989187 - 30002202 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for MBOAT4:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2736827CNV Deletion23290073
    nsv831277CNV Gain17160897

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611940    OMIM disorders: --

    3 diseases for MBOAT4:    About MalaCards
    ileus    gastroparesis    anorexia nervosa


    MBOAT4 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: MBOAT4 (1 document)

    Export disorders for MBOAT4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MBOAT4 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with MBOAT4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Ghrelin octanoylation mediated by an orphan lipid transferase. (PubMed id 18443287)1, 2, 3 Gutierrez J.A.... Hale J.E. (2008)
    2. Ghrelin O-acyltransferase (GOAT) is expressed in prost ate cancer tissues and cell lines and expression is differentially regulated in vitro by ghrelin. (PubMed id 23879975)1 Seim I....Chopin L.K. (2013)
    3. The ghrelin O-acyltransferase-ghrelin system reduces T NF-a-induced apoptosis and autophagy in human visceral adipocytes. (PubMed id 22869322)1 Rodriguez A....Fruhbeck G. (2012)
    4. The expression of ghrelin O-acyltransferase (GOAT) in human tissues. (PubMed id 21646729)1 Lim C.T....Korbonits M. (2011)
    5. The ghrelin O-acyltransferase-ghrelin system: a novel regulator of glucose metabolism. (PubMed id 21150588)1 Heppner K.M....TschAPp M.H. (2011)
    6. Genetic studies on the ghrelin, growth hormone secreta gogue receptor (GHSR) and ghrelin O-acyl transferase (GOAT) genes. (PubMed id 21930173)1 Liu B....Korbonits M. (2011)
    7. Genetic variation of the ghrelin activator gene ghrel in O-acyltransferase (GOAT) is associated with anorexia nervosa. (PubMed id 21035823)1 MA1ller T.D....Hinney A. (2010)
    8. Expression and modulation of ghrelin O-acyltransferas e in cultured chondrocytes. (PubMed id 19479831)1 GA^mez R....Gualillo O. (2009)
    9. Production of n-octanoyl-modified ghrelin in cultured cells requires prohormone processing protease and ghrelin O-acyltransferase, a s well as n-octanoic acid. (PubMed id 19628676)1 Takahashi T....Kojima M. (2009)
    10. DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)2 Nusbaum C....Lander E.S. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 619373 HGNC: 32311 Ensembl:ENSG00000177669 euGenes: HUgn619373 ECgene: MBOAT4
    H-InvDB: MBOAT4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MBOAT4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MBOAT4 gene:
    Search GeneIP for patents involving MBOAT4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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