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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MBOAT2 Gene

protein-coding   GIFtS: 49
GCID: GC02M008910

membrane bound O-acyltransferase domain containing 2

(Previous name: O-acyltransferase (membrane bound) domain containing 2...)
(Previous symbol: OACT2)
  Search for MBOAT2
in
MalaCards
our new
 Human Malady Compendium 
Biological research products
for MBOAT2    

Aliases
for MBOAT2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Membrane Bound O-Acyltransferase Domain Containing 21 2     LPEAT2 3
OACT21 2 3     LPLAT 22 3
O-Acyltransferase (Membrane Bound) Domain Containing 21 2     O-Acyltransferase Domain-Containing Protein 22 3
Lyso-PA Acyltransferase2 3     LPCAT42 5
Lyso-PE Acyltransferase2 3     FLJ144151
Lysophosphatidic Acid Acyltransferase2 3     FLJ902981
Lysophosphatidylethanolamine Acyltransferase2 3     Lysophospholipid Acyltransferase 22
Membrane-Bound O-Acyltransferase Domain-Containing Protein 22 3     EC 2.3.1.-3
1-Acylglycerophosphate O-Acyltransferase2 3     EC 2.3.1.513
1-Acylglycerophosphoethanolamine O-Acyltransferase2 3     EC 2.3.1.N71
LPAAT2 3     

External Ids:    HGNC: 251931   Entrez Gene: 1296422   Ensembl: ENSG000001437977   OMIM: 6119495   UniProtKB: Q6ZWT73   

Export aliases for MBOAT2 gene to outside databases

Previous GC identifer: GC02M008843


Summaries
for MBOAT2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: MBOA2_HUMAN, Q6ZWT7
Function: Acyltransferase which mediates the conversion of lysophosphatidylethanolamine
(1-acyl-sn-glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine
(1,2-diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity). Catalyzes also the acylation of lysophosphatidic
acid (LPA) into phosphatidic acid (PA) (LPAAT activity). Has also a very weak lysophosphatidylcholine acyltransferase
(LPCAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the
reacylation step of the phospholipid remodeling pathway also known as the Lands cycle




Genomic Views
for MBOAT2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_005334.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MBOAT2 gene promoter:
         HFH-3   USF1   Sox5   Nkx2-2   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   FOXI1   RORalpha1   USF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MBOAT2 promoter sequence
   Search SABiosciences Chromatin IP Primers for MBOAT2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MBOAT2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p25.1   Ensembl cytogenetic band:  2p25.1   HGNC cytogenetic band: 2p25

MBOAT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MBOAT2 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M008910:  view genomic region     (about GC identifiers)

Start:
 8,992,820 bp from pter      End:
 9,143,942 bp from pter
Size:
 151,123 bases      Orientation:
 minus strand

Proteins
for MBOAT2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: MBOA2_HUMAN, Q6ZWT7 (See protein sequence)
Recommended Name: Lysophospholipid acyltransferase 2  
Size: 520 amino acids; 59527 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Sequence caution: Sequence=BAC11204.1; Type=Erroneous initiation;
Secondary accessions: A9EDR2 Q8NCE7 Q96KY4

Explore the universe of human proteins at neXtProt for MBOAT2: NX_Q6ZWT7

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q6ZWT7

    • MBOAT2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_620154.2  
    ENSEMBL proteins: 
     ENSP00000302177   ENSP00000419573   ENSP00000420114   ENSP00000417409  
    Reactome Protein details: Q6ZWT7
    Human Recombinant Protein Products: 
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    Novus Biologicals MBOAT2 Protein
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for MBOAT2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane TAS--
    GO:0016021integral to membrane IEA--


    MBOAT2 for ontologies           About GeneDecksing



    MBOAT2 Antibody Products: 
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    Uscn Antibodies for MBOAT2
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    Uscn ELISAs and CLIAs for MBOAT2

    Protein Domains /
    Families
    for MBOAT2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    MBOAT2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR004299 MBOAT_fam

    Graphical View of Domain Structure for InterPro Entry Q6ZWT7

    ProtoNet protein and cluster: Q6ZWT7

    UniProtKB/Swiss-Prot: MBOA2_HUMAN, Q6ZWT7
    Similarity: Belongs to the membrane-bound acyltransferase family


    Function
    for MBOAT2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: MBOA2_HUMAN, Q6ZWT7
    Function: Acyltransferase which mediates the conversion of lysophosphatidylethanolamine
    (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine
    (1,2-diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity). Catalyzes also the acylation of lysophosphatidic
    acid (LPA) into phosphatidic acid (PA) (LPAAT activity). Has also a very weak lysophosphatidylcholine acyltransferase
    (LPCAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the
    reacylation step of the phospholipid remodeling pathway also known as the Lands cycle
    Catalytic activity: Acyl-CoA + 1-acyl-sn-glycero-3-phosphoethanolamine = CoA +
    1,2-diacyl-sn-glycero-3-phosphoethanolamine
    Catalytic activity: Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate
    Enzyme regulation: Partially inhibited by thimerosal

    Enzyme Numbers (IUBMB): EC 2.3.1.n71 EC 2.3.1.511 EC 2.3.1.-1

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MBOAT2
    8/61 QIAGEN miScript miRNA Assays for microRNAs that regulate MBOAT2 (see all 61):
    hsa-miR-579 hsa-miR-4291 hsa-miR-607 hsa-miR-429 hsa-miR-25 hsa-miR-3653 hsa-miR-877* hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmid: MBOAT2 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MBOAT2 (see all 7)
    OriGene shRNA RFP: MBOAT2
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MBOAT2

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for MBOAT2

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MBOAT2 (see all 4)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MBOAT2 

    Cell Line
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    Search LifeMap BioReagents cell lines for MBOAT2

    In Situ Assay
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:00038411-acylglycerol-3-phosphate O-acyltransferase activity IEA--


    MBOAT2 for ontologies           About GeneDecksing



    Pathways & Interactions
    for MBOAT2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Glycerophospholipid biosynthesis
    		Glycerophospholipid biosynthesis1.00
    		Glycerophospholipid metabolism0.54
    		Phospholipid metabolism0.64
    2CDP-diacylglycerol biosynthesis I
    		CDP-diacylglycerol biosynthesis I1.00
    		triacylglycerol biosynthesis0.50
    		phosphatidylglycerol biosynthesis II (non-plastidic)0.94
    3Metabolism
    		Metabolism1.00
    		Metabolism of lipids and lipoproteins0.34
    		Metabolic pathways0.38
    4Acyl chain remodelling of PE
    		Acyl chain remodelling of PE1.00
    		Acyl chain remodelling of PC0.85
    5Glycerolipid metabolism
    		Glycerolipid metabolism1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3 BioSystems Pathways for MBOAT2 
        CDP-diacylglycerol biosynthesis I
    triacylglycerol biosynthesis
    phosphatidylglycerol biosynthesis II (non-plastidic)

    5/6        Reactome Pathways for MBOAT2 (see all 6)
        Acyl chain remodelling of PE
    Glycerophospholipid biosynthesis
    Metabolism
    Acyl chain remodelling of PC
    Phospholipid metabolism


    3         Kegg Pathways  (Kegg details for MBOAT2):
        Glycerolipid metabolism
    Glycerophospholipid metabolism
    Metabolic pathways

    UniProtKB/Swiss-Prot: MBOA2_HUMAN, Q6ZWT7
    Pathway: Lipid metabolism; phospholipid metabolism


    MBOAT2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MBOAT2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/54 Interacting proteins for MBOAT2 (Q6ZWT73 ENSP000003021774) via UniProtKB, MINT, STRING, and/or I2D (see all 54)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    PISDQ9UG563, ENSP000002660954I2D: score=1 STRING: ENSP00000266095
    PEMTQ9UBM13, ENSP000002553894I2D: score=1 STRING: ENSP00000255389
    FNBP1LQ5T0N53I2D: score=5 
    AGPAT1Q999433I2D: score=1 
    ATP2C1P981943I2D: score=1 
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006644phospholipid metabolic process TAS--
    GO:0008654phospholipid biosynthetic process ----
    GO:0036151phosphatidylcholine acyl-chain remodeling TAS--
    GO:0036152phosphatidylethanolamine acyl-chain remodeling TAS--
    GO:0044281small molecule metabolic process TAS--


    MBOAT2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for MBOAT2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MBOAT2
    Search CenterWatch for drugs/clinical trials and news about MBOAT2 / MBOA2 

    Transcripts
    for MBOAT2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for MBOAT2 gene: 
    NM_138799.2  

    Unigene Clusters for MBOAT2:

    Membrane bound O-acyltransferase domain containing 2
    Hs.467634  [show with all ESTs], Hs.593538  [show with all ESTs]
    Unigene Representative Sequences: NM_138799, AF052107
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000305997(uc002qzg.1 uc010yix.1) ENST00000471753 ENST00000486315
    ENST00000473432 ENST00000486484 ENST00000494760 ENST00000477073 ENST00000474341
    ENST00000462696 ENST00000460786

    miRNA
    Products:             		 OriGene 3'-UTR Clone: MBOAT2
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MBOAT2
    8/61 QIAGEN miScript miRNA Assays for microRNAs that regulate MBOAT2 (see all 61):
    hsa-miR-579 hsa-miR-4291 hsa-miR-607 hsa-miR-429 hsa-miR-25 hsa-miR-3653 hsa-miR-877* hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmid: MBOAT2 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MBOAT2 (see all 7)
    OriGene shRNA RFP: MBOAT2
    OriGene siRNA: MBOAT2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MBOAT2
    Clone
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    GenScript: all cDNA clones in your preferred vector: MBOAT2 (NM_138799)
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    Primer
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    Additional cDNA sequence: AF052107.1 

    14 DOTS entries:

    DT.97760554  DT.114404  DT.100044364  DT.441494  DT.120965098  DT.40240092  DT.91887369  DT.120965086 
    DT.120965102  DT.100888874  DT.95356882  DT.120965077  DT.91817896  DT.100703505 

    24/118 AceView cDNA sequences (see all 118):

    NM_138799 AA789002 AI925869 AA332287 AW188870 AL118923 AA449282 H61476 
    BM693872 AI040666 AK074779 W60959 W94209 BM981049 BM126230 AW861164 
    BX954983 BC016005 BP361986 CA446769 BU619763 CF122771 BM836696 BX327428 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for MBOAT2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13
    SP1:                                                                                    
    SP2:              -     -     -                                                         


    ECgene alternative splicing isoforms for MBOAT2

    Expression
    for MBOAT2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MBOAT2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTTGAAATGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See MBOAT2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MBOAT2

    SOURCE GeneReport for Unigene clusters: Hs.467634 Hs.593538

    UniProtKB/Swiss-Prot: MBOA2_HUMAN, Q6ZWT7
    Tissue specificity: Expressed in neutrophils

        SABiosciences Custom PCR Arrays for MBOAT2
    Primer
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    In Situ
    Assay Products:     
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    Orthologs
    for MBOAT2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MBOAT2 gene from 8/29 species (see all 29)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves MBOAT21 membrane bound O-acyltransferase domain containing more 81.59(n)
    82.75(a)    		   421925  NM_001031090.1  NP_001026261.1 
    lizard
    (Anolis carolinensis)    		 Reptilia MBOAT26
    		 --
    		 77(a)
    		 1 ↔ 1
    		 1(148791621-148873413)
    zebrafish
    (Danio rerio)    		 Actinopterygii BI710672.12   -- 77.31(n)    BI710672.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta oys1 oysgedart 46.73(n)
    40.59(a)    		   36045  NM_136702.2  NP_610546.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea mboa-41 Protein MBOA-4 45.37(n)
    36.81(a)    		   182414  NM_069690.1  NP_502091.1 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes ALE1(YOR175C)4
    ALE11    		 Broad-specificity lysophospholipid acyltransferase, more4
    Ale1p1    		 44.98(n)1
    31.47(a)1    		   15(661674-659815)4
    8543461, 4  NP_014818.11, 4 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT1G630501 membrane bound O-acyl transferase domain-containing more 43.95(n)
    31.11(a)    		   842608  NM_104983.4  NP_176493.1 
    rice
    (Oryza sativa)    		 Liliopsida Os02g06760001 hypothetical protein 41.67(n)
    28.7(a)    		   4330302  NM_001054258.1  NP_001047723.1 


    ENSEMBL Gene Tree for MBOAT2 (if available)
    TreeFam Gene Tree for MBOAT2 (if available) 

    Paralogs
    for MBOAT2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MBOAT2 gene
    LPCAT32  MBOAT42  MBOAT12  MBOAT72  
    1 SIMAP similar gene for MBOAT2 using alignment to 4 protein entries:     MBOA2_HUMAN (see all proteins):
    MBOAT1

    MBOAT2 for paralogs           About GeneDecksing



    Genomic Variants
    for MBOAT2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2105 NCBI SNPs in MBOAT2 are shown (see all 2105)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 2 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1880916321,2
    		--8996230(+) CAGGGG/TTATGA 1 -- ds50010--------
    rs1484132611,2
    		C,--8996240(+) AAATC-/AAGTCA 1 -- ds50010--------
    rs15502561,2
    		C,F,A,H,--8996323(-) ATGATC/TTTGGC 1 -- ds50019Minor allele frequency- T:0.12NS EA NA WA 646
    rs15502551,2
    		C,F,O,A,H,--8996326(-) AATATG/AATCTT 1 -- ds500120Minor allele frequency- A:0.28NS EA NA WA CSA 2344
    rs1130021771,2
    		--8996377(+) GCTGAG/TAAATA 1 -- ds50012Minor allele frequency- T:0.05CSA WA 120
    rs1411260631,2
    		--8996438(+) CAAAA-/CACAAAAA 1 -- ds50010--------
    rs15502541,2
    		C,F,A,--8996728(-) CAGCCC/TGGGTG 1 -- ut31 ese34Minor allele frequency- T:0.33MN NA 190
    rs133880061,2
    		C,F,A,--8996746(+) GTGGCA/GCAATT 1 -- ut31 ese34Minor allele frequency- G:0.38NA WA 8
    rs1466124631,2
    		--8996874(+) GAGACA/GGGGAT 1 -- ut310--------
    rs67450921,2
    		C,F,A,--8996878(+) cggggA/Tttcac 1 -- ut31 ese34Minor allele frequency- T:0.38NA WA 8

    HapMap Linkage Disequilibrium report for MBOAT2 (8992820 - 9143942 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for MBOAT2
         2 CNVs: 50590 50589

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    Disorders / Diseases
    for MBOAT2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    MBOAT2 for disorders           About MalaCards

    MBOAT2 for disorders           About GeneDecksing

    OMIM gene information: 611949    OMIM disorders: --


    Export disorders for MBOAT2 gene to outside databases

    Publications
    for MBOAT2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MBOAT2 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with MBOAT2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. LPT1 encodes a membrane-bound O-acyltransferase involved in the acylation of lysophospholipids in the yeast Saccharomyces cerevisiae. (PubMed id 17890783)1, 2 Tamaki H.... Kumagai H. (2007)
    2. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils. (PubMed id 18772128)2 Gijon M.A.... Voelker D.R. (2008)
    6. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    8. Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1 Yu W.... Gibbs R.A. (1997)
    9. A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1 Andersson B.... Gibbs R.A. (1996)

    External Searches for MBOAT2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Genome Databases showing MBOAT2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 129642 HGNC: 25193 AceView: OACT2 Ensembl:ENSG00000143797 euGenes: HUgn129642
    ECgene: MBOAT2 Kegg: 129642 H-InvDB: MBOAT2

    Other Databases showing MBOAT2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing MBOAT2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MBOAT2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for MBOAT2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for MBOAT2 gene:
    Search GeneIP for patents involving MBOAT2

    GeneCards and IP:
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