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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MBOAT1 Gene

protein-coding   GIFtS: 49
GCID: GC06M020102

membrane bound O-acyltransferase domain containing 1

(Previous name: O-acyltransferase (membrane bound) domain containing 1...)
(Previous symbol: OACT1)
 Explore 5 diseases affiliated with
MBOAT1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for MBOAT1    

Aliases
for MBOAT1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Membrane Bound O-Acyltransferase Domain Containing 11 2     LPLAT 12 3
OACT11 2 3     O-Acyltransferase Domain-Containing Protein 12 3
LPEAT11 2     MGC446691
DJ434O11.11     12
O-Acyltransferase (Membrane Bound) Domain Containing 11 2     LPLAT2
Lyso-PS Acyltransferase2 3     Lysophosphatidylethanolamine Acyltransferase 12
Lysophosphatidylserine Acyltransferase2 3     Lysophospholipid Acyltransferase 12
Membrane-Bound O-Acyltransferase Domain-Containing Protein 12 3     EC 2.3.1.-3
1-Acylglycerophosphoserine O-Acyltransferase2 3     EC 2.3.1.N61
LPSAT2 3     

External Ids:    HGNC: 215791   Entrez Gene: 1541412   Ensembl: ENSG000001721977   OMIM: 6117325   UniProtKB: Q6ZNC83   

Export aliases for MBOAT1 gene to outside databases

Previous GC identifer: GC06M020209


Summaries
for MBOAT1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for MBOAT1:
This gene belongs to the membrane-bound O-acetyltransferase superfamily. The encoded transmembrane protein is an enzyme
that transfers organic compounds, preferably from oleoyl-CoA, to hydroxyl groups of protein targets in membranes. A
translocation disrupting this gene may be associated with brachydactyly syndactyly syndrome. Alternately spliced
transcript variants have been described for this gene. (provided by RefSeq, Nov 2012)

UniProtKB/Swiss-Prot: MBOA1_HUMAN, Q6ZNC8
Function: Acyltransferase which mediates the conversion of lysophosphatidylserine
(1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) into phosphatidylserine
(1,2-diacyl-sn-glycero-3-phospho-L-serine or PS) (LPSAT activity). Prefers oleoyl-CoA as the acyl donor.
Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also
known as the Lands cycle




Genomic Views
for MBOAT1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MBOAT1 gene promoter:
         MEF-2   MEF-2A   POU2F1   POU2F1b   POU2F1a   FOXO4   FOXO1a   STAT3   POU2F1c   FOXO1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for MBOAT1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MBOAT1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p22.3   Ensembl cytogenetic band:  6p22.3   HGNC cytogenetic band: 6p22.3

MBOAT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MBOAT1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M020102:  view genomic region     (about GC identifiers)

Start:
 20,100,935 bp from pter      End:
 20,212,670 bp from pter
Size:
 111,736 bases      Orientation:
 minus strand

Proteins
for MBOAT1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: MBOA1_HUMAN, Q6ZNC8 (See protein sequence)
Recommended Name: Lysophospholipid acyltransferase 1  
Size: 495 amino acids; 56557 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: A9EDQ5 B4DL59 B4E3J4 Q86XC2 Q8N9R5
Alternative splicing: 3 isoforms:  Q6ZNC8-1   Q6ZNC8-2   Q6ZNC8-3   

Explore the universe of human proteins at neXtProt for MBOAT1: NX_Q6ZNC8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2 (MBOAT1)
  • View neXtProt modification sites for NX_Q6ZNC8

    • MBOAT1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001073949.1  
    ENSEMBL proteins: 
     ENSP00000324944   ENSP00000441568   ENSP00000439814  
    Reactome Protein details: Q6ZNC8
    Human Recombinant Protein Products: 
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    Uscn Proteins for MBOAT1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane TAS--
    GO:0016021integral to membrane IEA--


    MBOAT1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for MBOAT1

    Protein Domains /
    Families
    for MBOAT1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    MBOAT1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR004299 MBOAT_fam

    Graphical View of Domain Structure for InterPro Entry Q6ZNC8

    ProtoNet protein and cluster: Q6ZNC8

    UniProtKB/Swiss-Prot: MBOA1_HUMAN, Q6ZNC8
    Similarity: Belongs to the membrane-bound acyltransferase family


    Function
    for MBOAT1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: MBOA1_HUMAN, Q6ZNC8
    Function: Acyltransferase which mediates the conversion of lysophosphatidylserine
    (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) into phosphatidylserine
    (1,2-diacyl-sn-glycero-3-phospho-L-serine or PS) (LPSAT activity). Prefers oleoyl-CoA as the acyl donor.
    Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also
    known as the Lands cycle
    Catalytic activity: Acyl-CoA + 1-acyl-sn-glycero-3-phosphatidylserine = CoA +
    1,2-diacyl-sn-glycero-3-phosphatidylserine
    Enzyme regulation: Partially inhibited by thimerosal

    Enzyme Numbers (IUBMB): EC 2.3.1.n61 EC 2.3.1.-1

    miRNA
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    hsa-miR-30c hsa-miR-4311 hsa-miR-181c hsa-miR-30d hsa-miR-103a hsa-miR-3692 hsa-miR-30a hsa-miR-4325
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    Inhib. RNA
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    OriGene shRNA RFP: MBOAT1
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for MBOAT1

    In Situ Assay
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016747transferase activity, transferring acyl groups other than amino-acyl groups IEA--


    MBOAT1 for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for MBOAT1:
     Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e 


    Pathways & Interactions
    for MBOAT1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Glycerophospholipid biosynthesis
    		Glycerophospholipid biosynthesis1.00
    		Glycerophospholipid metabolism0.54
    		Phospholipid metabolism0.64
    2Metabolism
    		Metabolism1.00
    		Metabolism of lipids and lipoproteins0.34
    		Metabolic pathways0.38
    3Acyl chain remodelling of PE
    		Acyl chain remodelling of PE1.00
    		Acyl chain remodelling of PS0.74
    4Glycerolipid metabolism
    		Glycerolipid metabolism1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/6        Reactome Pathways for MBOAT1 (see all 6)
        Acyl chain remodelling of PE
    Acyl chain remodelling of PS
    Glycerophospholipid biosynthesis
    Metabolism
    Phospholipid metabolism


    3         Kegg Pathways  (Kegg details for MBOAT1):
        Glycerolipid metabolism
    Glycerophospholipid metabolism
    Metabolic pathways

    UniProtKB/Swiss-Prot: MBOA1_HUMAN, Q6ZNC8
    Pathway: Lipid metabolism; phospholipid metabolism


    MBOAT1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MBOAT1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/41 Interacting proteins for MBOAT1 (ENSP000003249444) via UniProtKB, MINT, STRING, and/or I2D (see all 41)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    AGPAT6ENSP000003801844STRING: ENSP00000380184
    AGPAT9ENSP000002644094STRING: ENSP00000264409
    CDS1ENSP000002958874STRING: ENSP00000295887
    CDS2ENSP000004198794STRING: ENSP00000419879
    GPAMENSP000002652764STRING: ENSP00000265276
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006644phospholipid metabolic process TAS--
    GO:0008654phospholipid biosynthetic process ----
    GO:0036150phosphatidylserine acyl-chain remodeling TAS--
    GO:0036152phosphatidylethanolamine acyl-chain remodeling TAS--
    GO:0044281small molecule metabolic process TAS--


    MBOAT1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for MBOAT1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MBOAT1
    Search CenterWatch for drugs/clinical trials and news about MBOAT1 / MBOA1 

    Transcripts
    for MBOAT1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for MBOAT1 gene: 
    NM_001080480.2  

    Unigene Cluster for MBOAT1:

    Membrane bound O-acyltransferase domain containing 1
    Hs.377830  [show with all ESTs]
    Unigene Representative Sequence: NM_001080480
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000324607 ENST00000541730(uc003ncx.1 uc011dji.1) ENST00000536798


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    hsa-miR-30c hsa-miR-4311 hsa-miR-181c hsa-miR-30d hsa-miR-103a hsa-miR-3692 hsa-miR-30a hsa-miR-4325
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    Inhib. RNA
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    OriGene shRNA RFP: MBOAT1
    OriGene siRNA: MBOAT1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MBOAT1
    Clone
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    Primer
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    Additional cDNA sequence: 

    AB305043.1 AK093994.1 AK131269.1 AK296857.1 AK304748.1 BC045695.1 BC150650.1 BC150652.1 
    NR_073465.1 

    3 DOTS entries:

    DT.409407  DT.40258532  DT.91753362 

    24/59 AceView cDNA sequences (see all 59):

    CA417675 BQ001168 AI734993 AW769471 CB130025 AA513216 BC045695 AA807913 
    AI377269 BI089687 BQ081977 CA489212 AX748402 BF356925 BX447408 BI868631 
    BI600326 BP872150 AK131269 AI032502 AK093994 AI024993 AA133721 BX482403 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for MBOAT1 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17
    SP1:                                                                                                                              
    SP2:                                                                                            -                                 
    SP3:              -     -     -     -                                                                                             
    SP4:              -     -                                                                                                         
    SP5:                                                                                                                    -         


    ECgene alternative splicing isoforms for MBOAT1

    Expression
    for MBOAT1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MBOAT1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    MBOAT1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Neural TubeDiencephalic Ventricular ZoneNeural Tube
    Neural TubeMesencephalic Ventricular ZoneNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See MBOAT1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MBOAT1

    SOURCE GeneReport for Unigene cluster: Hs.377830

    UniProtKB/Swiss-Prot: MBOA1_HUMAN, Q6ZNC8
    Tissue specificity: Expressed in neutrophils

        SABiosciences Custom PCR Arrays for MBOAT1
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    In Situ
    Assay Products:     
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    Orthologs
    for MBOAT1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MBOAT1 gene from 8/24 species (see all 24)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves MBOAT16
    		 O-acyltransferase (membrane bound) domain containi...
    		 75(a)
    		 1 ↔ 1
    		 2(60674443-60734068)
    lizard
    (Anolis carolinensis)    		 Reptilia MBOAT16
    		 --
    		 70(a)
    		 1 ↔ 1
    		 4(55850574-55890221)
    African clawed frog
    (Xenopus laevis)    		 Amphibia BX853279.12   -- 74.92(n)    BX853279.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii mboat11 membrane bound O-acyltransferase domain containing more 61.92(n)
    57.11(a)    		   572841  NM_001007396.2  NP_001007397.2 
    fruit fly
    (Drosophila melanogaster)    		 Insecta oys6
    		 oysgedart
    		 27(a)
    		 1 → many
    		 2R(5923268-5936123)
    worm
    (Caenorhabditis elegans)    		 Secernentea mboa-36
    mboa-46
    (see all 3)    		 Lysophospholipid acyltransferase; Protein MBOA-4
    (see all 3)    		 34(a)
    27(a)
    (see all 3)    		 many ↔ many
    many ↔ many
    (see all 3)    		 X(5519841-5522791)
    IV(11157128-11159471)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT1G126406
    AT1G630506
    		 MBOAT (membrane bound O-acyl transferase)-like pro...
    membrane bound O-acyl transferase domain-containin...
    		 27(a)
    26(a)
    		 many ↔ many
    many ↔ many
    		 1(4303312-4305798)
    1(23375884-23378291)
    rice
    (Oryza sativa)    		 Liliopsida --
    		 O-acyltransferase, putative, expressed
    		 25(a)
    		 1 → many
    		 2(27553334-27561180)


    ENSEMBL Gene Tree for MBOAT1 (if available)
    TreeFam Gene Tree for MBOAT1 (if available) 

    Paralogs
    for MBOAT1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MBOAT1 gene
    LPCAT32  MBOAT42  MBOAT72  MBOAT22  
    1 SIMAP similar gene for MBOAT1 using alignment to 1 protein entry:     MBOA1_HUMAN:
    MBOAT2

    MBOAT1 for paralogs           About GeneDecksing



    Genomic Variants
    for MBOAT1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2251 NCBI SNPs in MBOAT1 are shown (see all 2251)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1917919201,2
    		--20100664(+) GACAGC/TGAAGT 1 -- ds50010--------
    rs763046691,2
    		F,--20100690(+) TTTCCT/CTGTTA 1 -- ds50011Minor allele frequency- C:0.09WA 118
    rs22351411,2
    		C,F,H,--20100698(-) CCCCAC/GTTTAA 1 -- ds50014Minor allele frequency- G:0.00NS EA 420
    rs1824744081,2
    		--20100852(+) CACTAC/TCCTAA 1 -- ds50010--------
    rs132020771,2
    		H--20100951(+) ATGGGA/GACATA 1 -- ut314Minor allele frequency- G:0.00NS EA 370
    rs1878432881,2
    		--20100993(+) CGTTGA/GATTTG 1 -- ut310--------
    rs2013668081,2
    		--20101064(+) TTATT-/ATCATCAT 1 -- ut310--------
    rs671122431,2
    		C,--20101070(+) TCATC-/ATTATTAT 1 -- ut310--------
    rs17081,2
    		C,--20101072(+) ATCATT/CATTAT 1 -- ut311Minor allele frequency- C:0.00MN 184
    rs1927203891,2
    		--20101116(+) TCACAC/TAGAAT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for MBOAT1 (20100935 - 20212670 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for MBOAT1
         1 CNV: 81261
         2 Indels: 93531 12811

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for MBOAT1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    MBOAT1 for disorders           About GeneDecksing

    OMIM gene information: 611732    OMIM disorders: --

    5 diseases for MBOAT1:    About MalaCards
    brachydactyly-syndactyly syndrome    attention deficit hyperactivity disorder    syndactyly    brachydactyly
    cholesterol


    Export disorders for MBOAT1 gene to outside databases

    Publications
    for MBOAT1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MBOAT1 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with MBOAT1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Discovery of a lysophospholipid acyltransferase family essential for membrane asymmetry and diversity. (PubMed id 18287005)1, 3 Hishikawa D....Shimizu T. (2008)
    2. Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils. (PubMed id 18772128)1, 2 Gijon M.A.... Voelker D.R. (2008)
    3. LPT1 encodes a membrane-bound O-acyltransferase involved in the acylation of lysophospholipids in the yeast Saccharomyces cerevisiae. (PubMed id 17890783)1, 2 Tamaki H.... Kumagai H. (2007)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    8. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    9. Genome-wide association of lipid-lowering response to statins in combined study populations. (PubMed id 20339536)1 Barber M.J....Krauss R.M. (2010)
    10. Acyl-CoA:lysophospholipid acyltransferases. (PubMed id 18718904)1 Shindou H. and Shimizu T. (2009)

    External Searches for MBOAT1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing MBOAT1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 154141 HGNC: 21579 AceView: OACT1 Ensembl:ENSG00000172197 euGenes: HUgn154141
    ECgene: MBOAT1 Kegg: 154141 H-InvDB: MBOAT1

    Other Databases showing MBOAT1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing MBOAT1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MBOAT1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for MBOAT1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for MBOAT1 gene:
    Search GeneIP for patents involving MBOAT1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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