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mannose-binding lectin (protein A) 1, pseudogene(Previous names: mannose-binding lectin (protein A) 1, pseudogene 1 )
(Previous symbol: MBL1P1)
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Aliases
for MBL1P gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Mannose-Binding Lectin (Protein A) 1, Pseudogene1 2 | | COLEC3P1 2 | | MBL1P11 2 | | Mannose-Binding Lectin (Protein A) 1, Pseudogene 11 |
| External Ids: | HGNC: 69211 | Entrez Gene: 85122 | Ensembl: ENSG000002426007 | | ORGUL members: | |
|---|
| NONCODE:n325936 n381512 | |
Export aliases for MBL1P gene to outside databasesPrevious GC identifers: GC10P081671 GC10P081667 GC10P075522
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Summaries
for MBL1P gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for MBL1P gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for MBL1P
Other transcription factors
Search SABiosciences Chromatin IP Primers for MBL1P
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MBL1P |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q22.3 Ensembl cytogenetic band: 10q22.3 HGNC cytogenetic band: 10q22.3MBL1P Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P081673: view genomic region
(about GC identifiers)
Start:
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81,664,654 bp from pter |
End:
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81,710,092 bp from pter |
Size:
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45,439 bases |
Orientation:
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plus strand |
ORGUL member locations:
Legend (see complete legend)
81664653 81687718 81710783 chr10
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Proteins
for MBL1P gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB: --
|
Protein
Domains /
Families
for MBL1P gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| -- |
Function
for MBL1P gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MBL1P |
1 GenomeRNAi human phenotype for MBL1P:
Animal Models:
Mouse knock-outs for MBL1P: Mbl1tm1Rala Mbl1tm1Mnz Mbl1tm1.1Mnz Mbl1tm1Kata
6 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Mbl1):
MBL1P for phenotypes About GeneDecksing
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Pathways & Interactions
for MBL1P gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MBL1P
|
Drugs & Compounds
for MBL1P gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MBL1P
Search CenterWatch for drugs/clinical trials and news about MBL1P 
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Transcripts
for MBL1P gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
4 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000453174(uc021puw.1) ENST00000480805(uc001kbg.1) ENST00000497731
ENST00000421889
21 AceView cDNA sequences: BU621784 BU580377 BX281221 BU580833 AF019382 BX117567 BV205084 CB242166 AA699400 BI823033 BC071736 BX102447 BQ631805 AI634387 BQ778042 AI827048 AI286161 H92757 AA628220 BF909938 AW104610
GeneLoc Exon Structure
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Expression
for MBL1P gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MBL1P expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
Genevestigator expression for MBL1P
SABiosciences Custom PCR Arrays for MBL1P
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MBL1P
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat MBL1P | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MBL1P | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MBL1P | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MBL1P |
Orthologs
for MBL1P gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of human and mouse.
Orthologs for MBL1P gene from 1 species (see representative species ) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Mbl15 |
mannose-binding lectin (protein A) 1 |
-- |
|
14 (22.36 cM) 41151456 |
ENSEMBL Gene Tree for MBL1P (if available)
TreeFam Gene Tree for MBL1P (if available) |
Paralogs
for MBL1P gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MBL1P gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for MBL1P (81664654 - 81710092 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MBL1P: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MBL1P |
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Disorders
/ Diseases
for MBL1P gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MBL1P for disorders About GeneDecksing
3  diseases for MBL1P: About MalaCardshepatitis b hepatitis hepatitis b virus infection
Human Genome Epidemiology (HuGE) Navigator: MBL1P (0 documents)
Export disorders for MBL1P gene to outside databases
|
Publications
for MBL1P gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MBL1P gene integrated from 9 sources:
(articles sorted by number of sources associating them with MBL1P) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human ortholog of rhesus mannose-binding protein-A gene is an expressed pseudogene that localizes to chromosome 10. (PubMed id 9501312)1, 3 Guo N....Sastry K.N. (1998)
- The 'involution' of mannose-binding lectin. (PubMed id 16115813)1, 9 Seyfarth J....Madsen H.O. (2005)
- MBL1 gene in nonhuman primates. (PubMed id 21889966)1 Segat L. and Crovella S. (2011)
- Identification and analysis of unitary pseudogenes: h istoric and contemporary gene losses in humans and other primates. (PubMed id 20210993)1 Zhang Z.D....Gerstein M. (2010)
- Lack of association between hepatitis B virus infection and polymorphism of mannose-binding lectin gene in Korean population. (PubMed id 15716605)1 Cheong J.Y....Kim J.H. (2005)
- The effect of mannan-binding lectin variant alleles on coronary artery reactivity in healthy young men. (PubMed id 15458704)1 Aittoniemi J....Lehtimaki T. (2004)
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External Searches for MBL1P gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing MBL1P gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing MBL1P gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MBL1P gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MBL1P | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MBL1P gene:
Search GeneIP for patents involving MBL1P
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MBL1P gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MBL1P | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MBL1P | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | Browse 3'-UTR reporter clones for miRNA target validation | | | Browse OriGene untagged cDNA clones in CMV expression vector | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MBL1P | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MBL1P | | OriGene Custom Protein Services for MBL1P | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MBL1P | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MBL1P | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MBL1P | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MBL1P | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MBL1P | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MBL1P |
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 |  |  |  | |
| | | | Search Tocris compounds for MBL1P |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MBL1P |
|  |  |  | | | | Search ThermoFisher Antibodies for MBL1P |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MBL1P |
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