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Aliases for MBD3L5 Gene

Aliases for MBD3L5 Gene

  • Methyl-CpG Binding Domain Protein 3-Like 5 2 3
  • MBD3-Like Protein 5 4

External Ids for MBD3L5 Gene

Previous GeneCards Identifiers for MBD3L5 Gene

  • GC19P006983

Summaries for MBD3L5 Gene

GeneCards Summary for MBD3L5 Gene

MBD3L5 (Methyl-CpG Binding Domain Protein 3-Like 5) is a Protein Coding gene. An important paralog of this gene is MBD3.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MBD3L5 Gene

Genomics for MBD3L5 Gene

Regulatory Elements for MBD3L5 Gene

Genomic Location for MBD3L5 Gene

Start:
7,030,577 bp from pter
End:
7,033,011 bp from pter
Size:
2,435 bases
Orientation:
Plus strand

Genomic View for MBD3L5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MBD3L5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MBD3L5 Gene

Proteins for MBD3L5 Gene

  • Protein details for MBD3L5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NJ08-MB3L5_HUMAN
    Recommended name:
    Putative methyl-CpG-binding domain protein 3-like 5
    Protein Accession:
    A6NJ08
    Secondary Accessions:

    Protein attributes for MBD3L5 Gene

    Size:
    208 amino acids
    Molecular mass:
    22976 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • The MBD3L proteins are encoded by strongly repeated regions of the 19p13 chromosome. The exact number of functional copies is unclear, and some of them may represent pseudogenes

neXtProt entry for MBD3L5 Gene

Proteomics data for MBD3L5 Gene at MOPED

Post-translational modifications for MBD3L5 Gene

No Post-translational modifications

Other Protein References for MBD3L5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MBD3L5 Gene

Domains for MBD3L5 Gene

Protein Domains for MBD3L5 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MBD3L5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NJ08

UniProtKB/Swiss-Prot:

MB3L5_HUMAN :
  • A6NJ08
Family:
  • Belongs to the MBD3L family.
genes like me logo Genes that share domains with MBD3L5: view

No data available for Gene Families for MBD3L5 Gene

Function for MBD3L5 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MBD3L5 Gene

Localization for MBD3L5 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MBD3L5 Gene COMPARTMENTS Subcellular localization image for MBD3L5 gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MBD3L5 Gene

Pathways for MBD3L5 Gene

SuperPathways for MBD3L5 Gene

No Data Available

Interacting Proteins for MBD3L5 Gene

Gene Ontology (GO) - Biological Process for MBD3L5 Gene

None

No data available for Pathways by source for MBD3L5 Gene

Transcripts for MBD3L5 Gene

mRNA/cDNA for MBD3L5 Gene

(2) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MBD3L5

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for MBD3L5
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MBD3L5 Gene

No ASD Table

Relevant External Links for MBD3L5 Gene

GeneLoc Exon Structure for
MBD3L5
ECgene alternative splicing isoforms for
MBD3L5

Expression for MBD3L5 Gene

mRNA expression in normal human tissues for MBD3L5 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for MBD3L5 Gene

SOURCE GeneReport for Unigene cluster for MBD3L5 Gene Hs.717312

genes like me logo Genes that share expressions with MBD3L5: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MBD3L5 Gene

Orthologs for MBD3L5 Gene

This gene was present in the common ancestor of animals.

Orthologs for MBD3L5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 95 (a)
ManyToMany
-- 36
  • 96 (a)
ManyToMany
-- 36
  • 95 (a)
ManyToMany
MBD3L2 35
  • 98.22 (n)
  • 96.6 (a)
cow
(Bos Taurus)
Mammalia -- 36
  • 49 (a)
OneToMany
MBD3L3 35
  • 63.15 (n)
  • 50 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 35 (a)
OneToMany
LOC100688619 35
  • 63.27 (n)
  • 52.04 (a)
mouse
(Mus musculus)
Mammalia Mbd3l2 35
  • 56.91 (n)
  • 39.51 (a)
Mbd3l2 36
  • 31 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 24 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 21 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Mbd3l2 35
  • 57.56 (n)
  • 43.41 (a)
chicken
(Gallus gallus)
Aves MBD3 36
  • 25 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii mbd3a 36
  • 22 (a)
ManyToMany
mbd3b 36
  • 24 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta MBD-like 36
  • 12 (a)
OneToMany
Species with no ortholog for MBD3L5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MBD3L5 Gene

ENSEMBL:
Gene Tree for MBD3L5 (if available)
TreeFam:
Gene Tree for MBD3L5 (if available)

Paralogs for MBD3L5 Gene

Paralogs for MBD3L5 Gene

Selected SIMAP similar genes for MBD3L5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MBD3L5: view

Variants for MBD3L5 Gene

Sequence variations from dbSNP and Humsavar for MBD3L5 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs923868 -- 7,029,075(+) ctttg(C/G)tttcc upstream-variant-2KB
rs931533 -- 7,032,149(+) AGCAA(A/G)CCCTG intron-variant
rs1651761 -- 7,032,143(+) GACTT(C/T)AGCAA intron-variant
rs1651763 -- 7,033,336(+) CACCA(G/T)GCTGG downstream-variant-500B
rs1690412 -- 7,030,769(-) ATAAC(G/T)TTCCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MBD3L5 Gene

Variant ID Type Subtype PubMed ID
dgv136e55 CNV Gain 17911159
nsv517794 CNV Gain+Loss 19592680
dgv393n27 CNV Gain 19166990
esv2751809 CNV Gain 17911159
esv33729 CNV Gain+Loss 17666407
dgv3707n71 CNV Gain 21882294
dgv3708n71 CNV Gain 21882294
esv2751810 CNV Loss 17911159
nsv910954 CNV Loss 21882294
esv24114 CNV Gain+Loss 19812545
nsv821572 CNV Duplication 20802225
nsv510880 CNV Complex 20534489

Relevant External Links for MBD3L5 Gene

HapMap Linkage Disequilibrium report
MBD3L5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MBD3L5 Gene

Disorders for MBD3L5 Gene

No disorders were found for MBD3L5 Gene.

No data available for UniProtKB/Swiss-Prot for MBD3L5 Gene

Publications for MBD3L5 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4

Products for MBD3L5 Gene

Sources for MBD3L5 Gene

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