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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MAZ Gene

protein-coding   GIFtS: 55
GCID: GC16P029817

MYC-associated zinc finger protein (purine-binding transcription...

 Explore 25 diseases affiliated with
MAZ via our new
 Human Malady Compendium 
Biological research products
for MAZ
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor)1 2     MAZI2 3
ZF871 2 3 5     SAF-12 3
Pur-11 2 3     PUR12 5
ZNF8011 2 3     SAF-22
Zif871 2     SAF-32
Purine-Binding Transcription Factor2 3     Myc-Associated Zinc Finger Protein2
Serum Amyloid A-Activating Factor-12 3     Serum Amyloid A Activating Factor 12
Transcription Factor Zif872 3     Serum Amyloid A Activating Factor 22
Zinc Finger Protein 8012 3     Zinc-Finger Protein, 87 Kilodaltons2

External Ids:    HGNC: 69141   Entrez Gene: 41502   Ensembl: ENSG000001034957   OMIM: 6009995   UniProtKB: P562703   

Export aliases for MAZ gene to outside databases

Previous GC identifers: GC16M029338 GC16P030140 GC16P029816 GC16P029855 GC16P029725 GC16P027479


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MAZ_HUMAN, P56270
Function: May function as a transcription factor with dual roles in transcription initiation and termination. Binds to
two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple
G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced
expression of serum amyloid A proteins

Gene Wiki entry for MAZ


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MAZ gene promoter:
         GR   PPAR-gamma1   p53   HSF2   ATF-2   c-Myb   c-Jun   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMAZ promoter sequence
   Search SABiosciences Chromatin IP Primers for MAZ

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAZ


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p11.2   Ensembl cytogenetic band:  16p11.2   HGNC cytogenetic band: 16p11.2

MAZ Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAZ gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P029817:  view genomic region     (about GC identifiers)

Start:
29,817,427 bp from pter      End:
29,823,649 bp from pter
Size:
6,223 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MAZ_HUMAN, P56270 (See protein sequence)
Recommended Name: Myc-associated zinc finger protein  
Size: 477 amino acids; 48608 Da
Subunit: Interacts with BPTF
Subcellular location: Nucleus (Probable). Note=In brains of Alzheimer disease patients, present in a plaque-like
structures
Sequence caution: Sequence=AAB04121.1; Type=Erroneous initiation; Sequence=BAA12728.1; Type=Erroneous initiation;
Secondary accessions: A8QJL9 G5E927 Q15703 Q8NFN7 Q99443
Alternative splicing: 2 isoforms:  P56270-1   P56270-2   (May act as a dominant negative of isoform 1. Reduced expression during inflammatory conditions)

Explore the universe of human proteins at neXtProt for MAZ: NX_P56270

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P56270

  • MAZ Protein expression data from MOPED and PaxDb:    About this image 
    MAZ Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001036004.1  NP_001263204.1  NP_001263205.1  NP_002374.2  

    ENSEMBL proteins: 
     ENSP00000443956   ENSP00000313362   ENSP00000455726   ENSP00000461174   ENSP00000457310  
     ENSP00000219782   ENSP00000456179   ENSP00000460057   ENSP00000455794   ENSP00000455913  
     ENSP00000461630   ENSP00000455473   ENSP00000460877   ENSP00000458201   ENSP00000458376  

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    Browse Sino Biological Recombinant Proteins
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    Uscn Proteins for MAZ

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm ----

    MAZ for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for MAZ


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    MAZ for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry P56270

    ProtoNet protein and cluster: P56270

    1 Blocks protein family: IPB007086 C2H2-type zinc finger signature

    UniProtKB/Swiss-Prot: MAZ_HUMAN, P56270
    Similarity: Contains 6 C2H2-type zinc fingers


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MAZ_HUMAN, P56270
    Function: May function as a transcription factor with dual roles in transcription initiation and termination. Binds to
    two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple
    G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced
    expression of serum amyloid A proteins

         Genatlas biochemistry entry for MAZ:
    MYC-associated zinc finger gene,60kDa,housekeeping gene,involved in transcription termination and initiation,widely
    expressed except in kidney

         Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000979RNA polymerase II core promoter sequence-specific DNA binding IDA1502157
    GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity ----
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding ----
    GO:0003682chromatin binding ----
         
    MAZ for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for MAZ:
     Upregulation of Wnt/beta-caten 

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for MAZ 

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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1SIDS Susceptibility Pathways
    SIDS Susceptibility Pathways1.00


    1 BioSystems Pathway for MAZ 
        SIDS Susceptibility Pathways


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MAZ

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/9 Interacting proteins for MAZ (P562701, 3 ENSP000002197824) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DCCP431461, 3, ENSP000003891404EBI-1809742,EBI-1222919 I2D: score=3 STRING: ENSP00000389140
    BPTFQ128303, ENSP000003072084I2D: score=3 STRING: ENSP00000307208
    KEAP1Q141453, ENSP000001711114I2D: score=2 STRING: ENSP00000171111
    JUNP054123, ENSP000003602664I2D: score=1 STRING: ENSP00000360266
    CSNK2A1P684003, ENSP000002172444I2D: score=2 STRING: ENSP00000217244
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0006366transcription from RNA polymerase II promoter ----
    GO:0006367transcription initiation from RNA polymerase II promoter IDA1502157
    GO:0006369termination of RNA polymerase II transcription IDA1502157
    GO:0045944positive regulation of transcription from RNA polymerase II promoter ----

    MAZ for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    MAZ for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MAZ
    8 Novoseek chemical compound relationships for MAZ gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    zinc 71.4 70 11395515 (5), 12270922 (3), 1502157 (3), 19583771 (2) (see all 33)
    alanine 33 12 10448092 (2), 11809795 (1), 8831693 (1), 19028685 (1) (see all 6)
    chloramphenicol 25.8 2 8831693 (1), 9685418 (1)
    oligonucleotide 9.37 1 7794930 (1)
    threonine 4.33 1 11809795 (1)
    retinoic acid 2.67 3 11733135 (1), 11527412 (1)
    nitric oxide 0 2 12684688 (1)
    serine 0 6 10448092 (4)

    Search CenterWatch for drugs/clinical trials and news about MAZ 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MAZ gene (4 alternative transcripts): 
    NM_001042539.2  NM_001276275.1  NM_001276276.1  NM_002383.3  

    Unigene Cluster for MAZ:

    MYC-associated zinc finger protein (purine-binding transcription factor)
    Hs.23650  [show with all ESTs]
    Unigene Representative Sequence: NM_001042539
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000545521(uc010vdx.2) ENST00000322945(uc002dty.3) ENST00000562337
    ENST00000566906 ENST00000563402 ENST00000219782(uc002dtx.3) ENST00000561855
    ENST00000567444 ENST00000568411 ENST00000563012 ENST00000562557 ENST00000568544
    ENST00000569978 ENST00000568282 ENST00000565777 ENST00000562594 ENST00000568516


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    hsa-miR-328 hsa-miR-29a hsa-miR-449a hsa-miR-3150b-3p hsa-miR-3909 hsa-miR-615-5p hsa-miR-34c-5p hsa-miR-1237
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    Inhib. RNA
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    Additional cDNA sequence: 

    AF489858.1 AK074720.1 AK097472.1 BC039057.1 BC041629.1 D85131.1 EF059746.1 FJ532357.1 
    L01420.1 M93339.1 M94046.1 U33819.1 

    24/46 DOTS entries (see all 46):

    DT.95273488  DT.91710384  DT.100847254  DT.100690986  DT.100765516  DT.92448029  DT.95273487  DT.70103273 
    DT.100039732  DT.92448013  DT.100039729  DT.92448015  DT.100651885  DT.70100793  DT.100651875  DT.95149184 
    DT.100061000  DT.100772705  DT.100832590  DT.95273481  DT.100651881  DT.100651886  DT.100866101  DT.120697569 

    24/466 AceView cDNA sequences (see all 466):

    CR607928 BQ066482 CR623056 CR592729 AI692261 BQ061660 CR605202 CD106068 
    BQ055692 CA426222 BE883434 CR624746 BM679314 AA292926 AW160502 AA300258 
    BI333287 CF130948 CR603028 CR604629 BM928246 CA946297 CR590673 BQ053868 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for MAZ (see all 10)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e · 2f ^ 3 ^ 4a · 4b · 4c · 4d ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c · 8d ^ 9
    SP1:                                      -     -     -     -     -           -           -     -           -     -     -         
    SP2:                                      -     -     -     -     -           -           -     -                                 
    SP3:                                      -     -     -     -     -           -           -                                       
    SP4:                                            -     -     -     -           -           -     -                                 
    SP5:                                                  -     -     -           -           -                                       


    ECgene alternative splicing isoforms for MAZ

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MAZ expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TACCCCACCC
    MAZ Expression
    About this image
    See MAZ Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MAZ

    SOURCE GeneReport for Unigene cluster: Hs.23650

    UniProtKB/Swiss-Prot: MAZ_HUMAN, P56270
    Tissue specificity: Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and
    midfrontal cortex (at protein level)

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for MAZ gene from 4/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Maz1 , 5 MYC-associated zinc finger protein (purine-binding more1, 5 92.8(n)1
    98.32(a)1
      7 (69.28 cM)5
    171881  NM_010772.11  NP_034902.11 
     1270221435 
    lizard
    (Anolis carolinensis)
    Reptilia MAZ6
    --
    65(a)
    1 ↔ 1
    GL343279.1(225603-242872)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3984912 Myc-associated zinc finger protein 75.01(n)    AF060488.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CR762399.16
    CABZ01068263.16
    --
    65(a)
    40(a)
    many → 1
    many → 1
    12(4357264-4363999)
    3(21186552-21332644)


    ENSEMBL Gene Tree for MAZ (if available)
    TreeFam Gene Tree for MAZ (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MAZ gene
    VEZF12  PATZ12  
    18/98 SIMAP similar genes for MAZ using alignment to 14 protein entries:     MAZ_HUMAN (see all proteins) (see all similar genes):
    VEZF1    A-328A3.4    ZNF148    ZNF516    ZNF55    kr-znf3
    ZNF219    GZF1    KLF7    ZNF808    ZNF263    ZNF600
    ZNF740    BCL6B    DKFZp686N0199    ZNF19    ZNF22    ZNF253

    MAZ for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/106 NCBI SNPs in MAZ are shown (see all 106    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs735283411,2
    C,F--27480364(+) TTGCTC/TCATTT 1 -- ds50011Minor allele frequency- T:0.03WA 118
    rs1119245101,2
    C--27480525(+) CTCCTG/CAGAAA 1 -- ds50011Minor allele frequency- C:0.00CSA 1
    rs115589981,2
    C--27480617(+) GGCAAG/TATGCT 1 -- nc-transcript-variantese32Minor allele frequency- T:0.00NA 4
    rs10437661,2
    C,H--27480621(+) AGATGC/ATGAGC 1 -- nc-transcript-variantese37Minor allele frequency- A:0.03MN NS EA NA 580
    rs25168231,2
    H--27480709(+) ATGCCG/AAGGGC 1 -- nc-transcript-variant4Minor allele frequency- A:0.00NS EA 418
    rs25168241,2
    H--27480735(+) GGGCAG/AAGGGT 1 -- nc-transcript-variant4Minor allele frequency- A:0.00NS EA 416
    rs766369381,2
    --27480838(+) AGCAGC/TGGGGG 1 -- nc-transcript-variant0--------
    rs342865921,2
    C,F,H--27481117(-) CTGAAG/AGCAGC 1 -- int120Minor allele frequency- A:0.09NS EA NA CSA WA 2490
    rs1135051511,2
    --27481130(+) AGACTC/TACCGG 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs735283431,2
    C,F--27481383(+) GATACC/TGTGGG 1 -- int12Minor allele frequency- T:0.04WA EA 238

    HapMap Linkage Disequilibrium report for MAZ (29817427 - 29823649 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for MAZ
         2 CNVs: 4939 35383
         1 Indel: 72523

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    MAZ for disorders           About GeneDecksing

    OMIM gene information: 600999    OMIM disorders: --

    20/25 diseases for MAZ (see all 25):    About MalaCards
    multiple endocrine neoplasia    rheumatoid arthritis    chronic lymphocytic leukemia    acute myeloid leukemia
    amyloidosis    burkitt's lymphoma    lymphocytic leukemia    myeloid leukemia
    arthritis    colon adenocarcinoma    hepatitis b    leukemia
    pheochromocytoma    alzheimer's disease    osteoarthritis    breast carcinoma
    osteosarcoma    adenocarcinoma    breast cancer    hepatitis

    8 Novoseek disease relationships for MAZ gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    amyloidosis 53 2 12270922 (1), 15067082 (1)
    carcinoma embryonal 46.8 1 9294605 (1)
    atherosclerosis 27 3 12270922 (1), 15498774 (1), 15067082 (1)
    arthritis 25.5 3 15498774 (1), 15067082 (1), 17237427 (1)
    rheumatoid arthritis 1.93 1 12270922 (1)
    inflammation 0 4 19583771 (1), 17237427 (1), 19028685 (1)
    colorectal cancer 0 1 12509857 (1)
    tumors 0 4 17849429 (1), 16414245 (1), 17553155 (1), 17102092 (1)

    Human Genome Epidemiology (HuGE) Navigator: MAZ (1 document)

    Export disorders for MAZ gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MAZ gene, integrated from 9 sources (see all 83):
    (articles sorted by number of sources associating them with MAZ)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. MAZ, a zinc finger protein, binds to c-MYC and C2 gene sequences regulating transcriptional initiation and termination. (PubMed id 1502157)1, 2, 3, 9 Bossone S.A.... Marcu K.B. (1992)
    2. Isolation of a novel cDNA encoding a zinc-finger protein that binds to two sites within the c-myc promoter. (PubMed id 1567856)1, 2, 3, 9 Pyrc J.J.... Hall D.J. (1992)
    3. SAF-2, a splice variant of SAF-1, acts as a negative regulator of transcription. (PubMed id 12270922)1, 2, 9 Ray B.K.... Ray A. (2002)
    4. Members of the MAZ family: a novel cDNA clone for MAZ from human pancreatic islet cells. (PubMed id 8831693)1, 2, 9 Tsutsui H.... Yokoyama K.K. (1996)
    5. The serotonin 1a receptor gene contains a TATA-less promoter that responds to MAZ and Sp1. (PubMed id 8626793)1, 2, 9 Parks C.L. and Shenk T. (1996)
    6. Genomic organization and expression of a human gene for Myc- associated zinc finger protein (MAZ). (PubMed id 9685418)1, 2, 9 Song J.... Yokoyama K.K. (1998)
    7. Fetal Alz-50 clone 1 (FAC1) protein interacts with the Myc-associated zinc finger protein (ZF87/MAZ) and alters its transcriptional activity. (PubMed id 10727212)1, 2 Jordan-Sciutto K.L....Bowser R. (2000)
    8. Transcriptional synergy mediated by SAF-1 and AP-1: critical role of N-terminal polyalanine and two zinc finger domains of SAF-1. (PubMed id 19028685)1, 9 Kumar D....Ray B.K. (2009)
    9. Overexpression of serum amyloid A-activating factor 1 inhibits cell proliferation by the induction of cyclin-dependent protein kinase inhibitor p21WAF-1/Cip-1/Sdi-1 expression. (PubMed id 15067082)1, 9 Ray A....Ray B.K. (2004)
    10. Induction of matrix metalloproteinase 1 gene expression is regulated by inflammation-responsive transcription factor SAF-1 in osteoarthritis. (PubMed id 12528113)1, 9 Ray A....Ray B.K. (2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4150 HGNC: 6914 AceView: MAZ Ensembl:ENSG00000103495 euGenes: HUgn4150
    ECgene: MAZ H-InvDB: MAZ

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MAZ Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MAZ Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MAZ gene:
    Search GeneIP for patents involving MAZ

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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