Aliases for MAZ Gene
External Ids for MAZ Gene
Previous GeneCards Identifiers for MAZ Gene
GeneCards Summary for MAZ Gene
MAZ (MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor)) is a Protein Coding gene. Diseases associated with MAZ include chronic lymphocytic leukemia. Among its related pathways are SIDS Susceptibility Pathways. GO annotations related to this gene include RNA binding and sequence-specific DNA binding RNA polymerase II transcription factor activity. An important paralog of this gene is PATZ1.
UniProtKB/Swiss-Prot for MAZ Gene
May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.