MAX Gene
protein-coding GIFtS: 62
GCID: GC14M065472
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|
MYC associated factor X(Previous name: MAX protein )
| |
Aliases
for MAX gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| MYC Associated Factor X1 2 | | BHLHd81 | | BHLHd41 | | MAX Protein1 | | Class D Basic Helix-Loop-Helix Protein 42 3 | | Protein Max2 | | BHLHd51 | | BHLHD43 | | BHLHd61 | | Myc-Associated Factor X3 | | BHLHd71 | | |
Export aliases for MAX gene to outside databasesPrevious GC identifers: GC14M062799 GC14M059335 GC14M063462 GC14M063531 GC14M064542 GC14M045642 |
Summaries
for MAX gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MAX:
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family oftranscription factors. It is able to form homodimers and heterodimers with other family members, which include Mad,Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimersand heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides acomplex system of transcriptional regulation. Mutations of this gene have been reported to be associated withhereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternativesplicing results in multiple transcript variants. (provided by RefSeq, Aug 2012)
UniProtKB/Swiss-Prot: MAX_HUMAN, P61244Function: Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD whichrecognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAXcomplex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3'Lys-9' histone methyltransferase activity
Gene Wiki entry for MAX
|
Genomic Views
for MAX gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MAX gene promoter:
C/EBPalpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for MAX
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAX |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q23 Ensembl cytogenetic band: 14q23.3 HGNC cytogenetic band: 14q23MAX Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14M065472: view genomic region
(about GC identifiers)
Start:
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65,472,892 bp from pter |
End:
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65,569,413 bp from pter |
Size:
|
96,522 bases |
Orientation:
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minus strand |
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Proteins
for MAX gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MAX_HUMAN, P61244 (See
protein sequence)Recommended Name: Protein max Size: 160 amino acids; 18275 Da
Subunit: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MYC orMAD. Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2,MBLR, L3MBTL2 and YAF2. Component of some MLL1/MLL complex, at least composed of the core components MLL, ASH2L,HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L,MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9and TEX10. Interacts with SPAG9
Subcellular location: Nucleus
5 PDB 3D structures from  and Proteopedia  for MAX:1AN2 (3D)
1HLO (3D)
1NKP (3D)
1NLW (3D)
1R05 (3D)
Secondary accessions: A8K265 A8K4G4 A8K824 P25912 P52163 Q14803 Q96CY8Alternative splicing: 5 isoforms: P61244-1, P25912-1 P61244-2, P25912-2 P61244-3, P25912-3 P61244-4 P61244-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MAX: NX_P61244
Post-translational modifications:
Reversible lysine acetylation might regulate the nuclear-cytoplasmic shuttling of specific Max complexes1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P61244
MAX Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (7 alternative transcripts):
NP_001257997.1 NP_001257998.1 NP_002373.3 NP_660087.1 NP_660088.1 NP_660089.1 NP_932061.1
ENSEMBL proteins: ENSP00000342482 ENSP00000351175 ENSP00000378104 ENSP00000450763 ENSP00000284165 ENSP00000351490 ENSP00000452405 ENSP00000451907 ENSP00000450955 ENSP00000452206 ENSP00000452378 ENSP00000452286 ENSP00000452197 ENSP00000450818 ENSP00000246163
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
MAX for ontologies About GeneDecksing
MAX Antibody Products:
Assay Products for MAX: |
Protein
Domains /
Families
for MAX gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MAX for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry P61244ProtoNet protein and cluster: P61244 UniProtKB/Swiss-Prot: MAX_HUMAN, P61244Similarity: Belongs to the MAX familySimilarity: Contains 1 bHLH (basic helix-loop-helix) domain |
Function
for MAX gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MAX_HUMAN, P61244Function: Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD whichrecognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAXcomplex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3'Lys-9' histone methyltransferase activity Genatlas biochemistry entry for MAX:Max protein,heterodimerizing with MYC,with high affinity for the DNA-binding site of MYC,binds to MAD and MNT
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAX (see all 9)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAX (see all 8)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 6): MAX (NM_197957) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MAX | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAX |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAX |
Gene Ontology (GO): 5/10 molecular function terms (GO ID links to tree view) (see all 10): About this table
MAX for ontologies About GeneDecksing
7 GenomeRNAi human phenotypes for MAX:
Animal Models:
Mouse knock-out Maxtm1Rdp for MAX
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Max):
MAX for phenotypes About GeneDecksing
|
Pathways & Interactions
for MAX gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/16 super-pathways (see all 16) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | MAPK signaling pathway | | | 2 | Rho Family GTPases | | | 3 | Apoptosis and Autophagy | | | 4 | Integrated Breast Cancer Pathway | | | 5 | p38 MAPK Signaling Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  R&D Systems Pathways for MAX
3 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for MAX
1 
Cell Signaling Technology (CST) Pathway for MAX
5/9  BioSystems Pathways for MAX (see all 9)
3 
Kegg Pathways (Kegg details for MAX):
MAX for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MAX
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/272 Interacting proteins for MAX (P612441, 2, 3 ENSP000003514904) via UniProtKB, MINT, STRING, and/or I2D (see all 272)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| MYC | P011061, 2, 3, ENSP000003672074 | EBI-878388,EBI-1058440 MINT-25075 MINT-73406 MINT-73138 I2D:
score=15 STRING: ENSP00000367207 | | MAD1L1 | Q9Y6D91, 3, ENSP000003825624 | EBI-878388,EBI-742610 I2D:
score=4 STRING: ENSP00000382562 | | GABBR1 | Q9UBS51, 3 | EBI-878388,EBI-724156 I2D:
score=1 | | EPAS1 | Q998141, 3, ENSP000002637344 | EBI-878388,EBI-447470 I2D:
score=3 STRING: ENSP00000263734 | | HSPA1A | P081073, ENSP000003648024 | I2D:
score=1 STRING: ENSP00000364802 |
About this table
Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
-- | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
-- | -- | | GO:0006366 | transcription from RNA polymerase II promoter |
TAS | 8425218 | | GO:0006461 | protein complex assembly |
IEA | -- | | GO:0009267 | cellular response to starvation |
IEA | -- |
MAX for ontologies About GeneDecksing
|
Drugs & Compounds
for MAX gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MAX for compounds About GeneDecksing
 Browse Tocris compounds for MAX
3 Novoseek chemical compound relationships for MAX gene About this table
Search CenterWatch for drugs/clinical trials and news about MAX
|
Transcripts
for MAX gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MAX gene (8 alternative transcripts): NM_001271068.1 NM_001271069.1 NM_002382.4 NM_145112.2 NM_145113.2 NM_145114.2 NM_197957.3 NM_145116.1 Unigene Cluster for MAX: MYC associated factor X Hs.285354 [show with all ESTs]Unigene Representative Sequence: BC03609218 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000341653 ENST00000358402 ENST00000394606(uc001xie.1 uc001xif.1 uc001xig.1 uc001xih.1)
ENST00000555932 ENST00000284165(uc001xij.1) ENST00000358664 ENST00000555419
ENST00000553928 ENST00000557277 ENST00000556892 ENST00000553951 ENST00000556979(uc001xic.1)
ENST00000555667(uc001xii.1) ENST00000557746 ENST00000556443 ENST00000246163(uc001xik.3)
ENST00000556702 ENST00000554709
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAX (see all 9)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAX (see all 8)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 6): MAX (NM_197957) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MAX | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAX |
Additional cDNA sequence: AK290130.1 AK290929.1 AK292189.1 AK292630.1 AK303412.1 AL833643.1 AY353088.1 BC003525.1 BC004516.2 BC013669.1 BC025685.1 BC027924.1 BC036092.1 CR542191.1 M64240.1 NR_073137.1 NR_073138.1 X60287.1 24/27 DOTS entries (see all 27): DT.95378414 DT.100037470 DT.100817243 DT.95122128 DT.100817250 DT.98131674 DT.100809293 DT.406416 DT.97853570 DT.120751852 DT.100758256 DT.70103755 DT.95263923 DT.91766090 DT.100817246 DT.120751700 DT.100802547 DT.120751516 DT.120751826 DT.95371931 DT.100037465 DT.100721347 DT.100817237 DT.120751794 24/306 AceView cDNA sequences (see all 306): AA535616 AI804933 CR542191 CR620686 BG389618 NM_145113 H14126 BM710151 NM_145112 BM989983 T16249 BF002710 AW242767 AI084145 BM714640 BM461636 AL691694 F01561 NM_002382 BE048876 CR619150 AY353088 BF196519 AW614081
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for MAX About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c |
|---|
|
| SP1: | | | | | | | - | | | | - | | | | - | | | | | | | | |
| SP2: | | | | | | | - | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | - | | - | | - | | | | | | | | |
| SP4: | | | | | | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MAX
|
Expression
for MAX gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MAX expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAAATAAAAA
About this image
See MAX Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MAX
SOURCE GeneReport for Unigene cluster: Hs.285354
UniProtKB/Swiss-Prot: MAX_HUMAN, P61244Tissue specificity: High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney andskeletal muscle
SABiosciences Expression via Pathway-Focused PCR Arrays including MAX:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAX
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MAX | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAX | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAX | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAX |
Orthologs
for MAX gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for MAX gene from 7/23 species (see all 23) About this table
ENSEMBL Gene Tree for MAX (if available)
TreeFam Gene Tree for MAX (if available) |
Paralogs
for MAX gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MAX gene
15 SIMAP similar genes for MAX using alignment to 11 protein entries: MAX_HUMAN (see all proteins):MYCL1 SREBF1 SREBP-1a (delta) SREBP-1c (delta) MYC N-myc
USF1 usf1-bd MLX TFAP4 MXD1 SREBF2
USF2 KIAA2018 WUGSC
MAX for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for MAX
PGOHUM00000233579
|
Genomic Variants
for MAX gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MAX (65472892 - 65569413 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for MAX
1 CNV: 101971
Human Gene Mutation Database (HGMD): MAX
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAX |
|
Disorders
/ Diseases
for MAX gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MAX for disorders About GeneDecksing
OMIM gene information: 154950
OMIM disorders: --
15  diseases for MAX: About MalaCardspheochromocytoma female stress incontinence williams-beuren syndrome teratocarcinoma
cholestasis lung cancer prostate cancer glioblastoma
cholesterol neuroblastoma prostatitis melanoma
adenocarcinoma neuronitis desmoplastic melanoma
4 Novoseek disease relationships for MAX gene About this table
Human Genome Epidemiology (HuGE) Navigator: MAX (129 documents)
Tumor Gene Database (TGDB): MAX
Export disorders for MAX gene to outside databases
|
Publications
for MAX gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MAX gene, integrated from 9 sources (see all 181):
(articles sorted by number of sources associating them with MAX) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Max is acetylated by p300 at several nuclear localization residues. (PubMed id 17217336)1, 2, 9 Faiola F.... Martinez E. (2007)
- Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. (PubMed id 2006410)1, 2, 9 Blackwood E.M. and Eisenman R.N. (1991)
- The crystal structure of an intact human Max-DNA complex: new insights into mechanisms of transcriptional control. (PubMed id 9115440)1, 2, 9 Brownlie P....Suck D. (1997)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
- Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. (PubMed id 15960975)1, 2 Dou Y.... Roeder R.G. (2005)
- An unappreciated role for RNA surveillance. (PubMed id 14759258)1, 2 Hillman R.T.... Brenner S.E. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A complex with chromatin modifiers that occupies E2F- and Myc- responsive genes in G0 cells. (PubMed id 12004135)1, 2 Ogawa H.... Nakatani Y. (2002)
- Alternative mRNA forms and open reading frames of the max gene. (PubMed id 8426752)1, 2 Vaestrik I.... Maekelae T.P. (1993)
|
External Searches for MAX gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MAX gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MAX gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MAX gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for MAX gene:
Search GeneIP for patents involving MAX
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MAX gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for MAX | | OriGene shRNA RFP for MAX | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MAX | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAX | | | OriGene Protein Over-expression Lysate for MAX | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MAX | | OriGene 3'-UTR Clone for MAX | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAX | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAX | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MAX | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MAX | | OriGene Custom Protein Services for MAX | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MAX | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAX | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAX | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAX | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAX | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAX |
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| | Antibodies & Assays for MAX |
| | | | Search Tocris compounds for MAX |
| |  |  |  |  | | | | | | Recombinant Protein for MAX |
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 | | | MAX Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAX |
|  |  |  | | | | ThermoFisher Antibodies for MAX |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAX |
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