MAT2B Gene
protein-coding GIFtS: 54
GCID: GC05P162930
|
|
methionine adenosyltransferase II, beta
| |
Aliases
for MAT2B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Methionine Adenosyltransferase II, Beta1 2 | | Nbla029992 | | MATIIbeta1 2 | | Beta Regulatory Subunit Of Methionine Adenosyltransferase2 | | SDR23E11 2 | | DTDP-4-Keto-6-Deoxy-D-Glucose 4-Reductase2 | | Putative DTDP-4-Keto-6-Deoxy-D-Glucose 4-Reductase2 3 | | Methionine Adenosyltransferase 2 Subunit Beta2 | | TGR2 3 | | Putative Protein Product Of Nbla029992 | | MAT II Beta2 3 | | Short Chain Dehydrogenase/Reductase Family 23E, Member 12 | | MAT-II2 | | Methionine Adenosyltransferase II Beta3 |
Export aliases for MAT2B gene to outside databasesPrevious GC identifers: GC05P163135 GC05P163523 GC05P162865 GC05P162911 GC05P162862 GC05P158029 |
Summaries
for MAT2B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MAT2B:
The protein encoded by this gene belongs to the methionine adenosyltransferase (MAT) family. MAT catalyzes thebiosynthesis of S-adenosylmethionine from methionine and ATP. This protein is the regulatory beta subunit of MAT.Alternative splicing results in multiple transcript variants encoding different isoforms. (provided by RefSeq, Nov2012)
UniProtKB/Swiss-Prot: MAT2B_HUMAN, Q9NZL9Function: Non-catalytic regulatory subunit of S-adenosylmethionine synthetase 2 (MAT2A), an enzyme that catalyzes theformation of S-adenosylmethionine from methionine and ATP. Regulates the activity of S-adenosylmethionine synthetase 2by changing its kinetic properties, rendering the enzyme more susceptible to S-adenosylmethionine inhibition
|
Genomic Views
for MAT2B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_023133.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MAT2B gene promoter:
RP58 Tal-1 FOXO4 c-Myb Evi-1 E47
Other transcription factors
Search SABiosciences Chromatin IP Primers for MAT2B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAT2B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q34-q35 Ensembl cytogenetic band: 5q34 HGNC cytogenetic band: 5q34-q35MAT2B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P162930: view genomic region
(about GC identifiers)
Start:
|
162,930,120 bp from pter |
End:
|
162,946,342 bp from pter |
Size:
|
16,223 bases |
Orientation:
|
plus strand |
|
Proteins
for MAT2B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MAT2B_HUMAN, Q9NZL9 (See
protein sequence)Recommended Name: Methionine adenosyltransferase 2 subunit beta Size: 334 amino acids; 37552 Da
Subunit: Heterotetramer composed of 2 catalytic alpha subunits (alpha and alpha') (MAT2A) and 1 copy of beta subunit(MAT2B)
Miscellaneous: Its expression in hepatoma cell lines may lead to increase DNA synthesis and thereby participate in cellproliferation
Sequence caution: Sequence=AAG39296.1; Type=Erroneous initiation;
2 PDB 3D structures from  and Proteopedia  for MAT2B:2YDX (3D)
2YDY (3D)
Secondary accessions: B2R5Y6 Q1WAI7 Q27J92 Q3LIE8 Q567T7 Q6NYC7 Q9BS89 Q9H3E1 Q9UJ54Alternative splicing: 5 isoforms: Q9NZL9-1 Q9NZL9-2 Q9NZL9-3 Q9NZL9-4 Q9NZL9-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MAT2B: NX_Q9NZL9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NZL9
MAT2B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_037415.1 NP_877725.1
ENSEMBL proteins: ENSP00000280969 ENSP00000427987 ENSP00000325425 ENSP00000397371 ENSP00000428046 ENSP00000431071 Reactome Protein details: Q9NZL9
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
MAT2B for ontologies About GeneDecksing
MAT2B Antibody Products:
Assay Products for MAT2B: |
Protein
Domains /
Families
for MAT2B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MAT2B for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NZL9ProtoNet protein and cluster: Q9NZL9 1 Blocks protein family: IPB005913 dTDP-4-dehydrorhamnose reductase
UniProtKB/Swiss-Prot: MAT2B_HUMAN, Q9NZL9Similarity: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily |
Function
for MAT2B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MAT2B_HUMAN, Q9NZL9Function: Non-catalytic regulatory subunit of S-adenosylmethionine synthetase 2 (MAT2A), an enzyme that catalyzes theformation of S-adenosylmethionine from methionine and ATP. Regulates the activity of S-adenosylmethionine synthetase 2by changing its kinetic properties, rendering the enzyme more susceptible to S-adenosylmethionine inhibition
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAT2B (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAT2B (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): MAT2B (NM_013283) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MAT2B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAT2B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAT2B |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
MAT2B for ontologies About GeneDecksing
|
Pathways & Interactions
for MAT2B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Methionine metabolism | | | 2 | Sulfur amino acid metabolism | | | 3 | Metabolism | | | 4 | Biological oxidations | | | 5 | Metabolism of amino acids and derivatives | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5  BioSystems Pathways for MAT2B
5/6 
Reactome Pathways for MAT2B (see all 6)
2 
Kegg Pathways (Kegg details for MAT2B):
UniProtKB/Swiss-Prot: MAT2B_HUMAN, Q9NZL9Pathway: Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step1/1
MAT2B for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MAT2B
STRING Interaction
Network Preview (showing 5 interactants - click image to see 14)
5/16 Interacting proteins for MAT2B (Q9NZL93 ENSP000003254254) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000096 | sulfur amino acid metabolic process |
TAS | -- | | GO:0006556 | S-adenosylmethionine biosynthetic process |
IEA | -- | | GO:0006730 | one-carbon metabolic process |
IEA | -- | | GO:0006805 | xenobiotic metabolic process |
TAS | -- | | GO:0032259 | methylation |
TAS | -- |
MAT2B for ontologies About GeneDecksing
|
Drugs & Compounds
for MAT2B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MAT2B
9 HMDB Compounds for MAT2B About this table
1 DrugBank Compound for MAT2B About this table
Search CenterWatch for drugs/clinical trials and news about MAT2B
|
Transcripts
for MAT2B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MAT2B gene (2 alternative transcripts): NM_013283.4 NM_182796.2 Unigene Cluster for MAT2B: Methionine adenosyltransferase II, beta Hs.54642 [show with all ESTs]Unigene Representative Sequence: AB0733909 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000280969(uc003lzj.3) ENST00000518731 ENST00000519719 ENST00000321757(uc003lzk.3)
ENST00000421814 ENST00000518095(uc003lzl.1) ENST00000523606 ENST00000520449
ENST00000521838(uc003lzm.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAT2B (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAT2B (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): MAT2B (NM_013283) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MAT2B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAT2B |
Additional cDNA sequence: AB073390.1 AF113225.1 AF182814.1 AJ243721.1 AK096178.1 AK291919.1 AK294069.1 AK312365.1 AL136664.1 AY358695.1 BC005218.1 BC066645.1 BC093030.1 DQ395260.1 DQ413182.1 DQ413183.1 12 DOTS entries: DT.453613 DT.40121770 DT.91759828 DT.100817406 DT.100817405 DT.100832330 DT.100036937 DT.95116883 DT.120841320 DT.95116862 DT.95116886 DT.97795674 24/316 AceView cDNA sequences (see all 316): AA774074 AI921148 AA577350 AA576719 BF941653 AW297058 CR622441 AI699076 AA228107 AA811454 BM807060 AA634119 NM_013283 N20102 CA306649 AA779556 BQ574443 BQ771904 AA541267 CR596100 AW195380 CR596069 CD515226 AA884602
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for MAT2B (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b |
|---|
|
| SP1: | | | | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MAT2B
|
Expression
for MAT2B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MAT2B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGATACATAC
About this image
See MAT2B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MAT2B
SOURCE GeneReport for Unigene cluster: Hs.54642
UniProtKB/Swiss-Prot: MAT2B_HUMAN, Q9NZL9Tissue specificity: Widely expressed
SABiosciences Custom PCR Arrays for MAT2B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAT2B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MAT2B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAT2B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAT2B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAT2B |
Orthologs
for MAT2B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for MAT2B gene from 7/25 species (see all 25) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Mat2b1 , 5 |
methionine adenosyltransferase II, beta1, 5 |
88.72(n)1
94.31(a)1 |
|
11 (24.40 cM)5
1086451 NM_134017.21 NP_598778.11
406793145 |
chicken
(Gallus gallus) |
Aves |
MAT2B1 |
methionine adenosyltransferase II, beta |
79.87(n)
88.5(a) |
|
416165 XM_414497.3 XP_414497.3 |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.191052 |
Transcribed sequence with moderate similarity to protein more |
78.31(n) |
|
BX773905.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb48h022 |
wufb48h02 |
73.73(n) |
|
322067 BI708448.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT4G005601 |
Rossmann-fold NAD(P)-binding domain-containing protein |
42.25(n)
29.17(a) |
|
827978 NM_116280.3 NP_191965.2 |
rice
(Oryza sativa) |
Liliopsida |
Os02g08262001 |
hypothetical protein |
42.82(n)
30.21(a) |
|
4331215 NM_001055120.1 NP_001048585.1 |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
rfbD6 |
dTDP-4-dehydrorhamnose reductase subunit, NAD(P)-b... |
22(a) |
1 ↔ 1 |
Chromosome(2109101-2110000) |
ENSEMBL Gene Tree for MAT2B (if available)
TreeFam Gene Tree for MAT2B (if available) |
Paralogs
for MAT2B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MAT2B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MAT2B (162930120 - 162946342 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for MAT2B
2 CNVs: 93332 81105 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAT2B |
|
Disorders
/ Diseases
for MAT2B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MAT2B for disorders About GeneDecksing
OMIM gene information: 605527
OMIM disorders: --
6  diseases for MAT2B: About MalaCardsspina bifida liver cancer neuroblastoma tuberculosis
carcinoma mycobacterium tuberculosis
Human Genome Epidemiology (HuGE) Navigator: MAT2B (7 documents)
Export disorders for MAT2B gene to outside databases
|
Publications
for MAT2B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MAT2B gene, integrated from 9 sources (see all 47):
(articles sorted by number of sources associating them with MAT2B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Regulation of the human MAT2B gene encoding the regulatory beta subunit of methionine adenosyltransferase, MAT II. (PubMed id 11337507)1, 2, 7, 9 LeGros L.... Kotb M. (2001)
- Cloning, expression, and functional characterization of the beta regulatory subunit of human methionine adenosyltransferase (MAT II). (PubMed id 10644686)1, 2, 3 LeGros H.L.... Kotb M. (2000)
- Methionine adenosyltransferase II beta subunit gene expression provides a proliferative advantage in human hepatoma. (PubMed id 12671891)1, 2, 9 Martinez-Chantar M.L.... Mato J.M. (2003)
- The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PubMed id 19027726)1, 3 Persson B.... Oppermann U. (2009)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
- Consensus nomenclature for the mammalian methionine adenosyltransferase genes and gene products. (PubMed id 9055605)1, 3 Kotb M....Cantoni G.L. (1997)
- Lentivirus mediated shRNA interference targeting MAT2B induces growth-inhibition and apoptosis in hepatocelluar carcinoma. (PubMed id 18698677)1, 9 Wang Q....Pan D.Y. (2008)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
|
External Searches for MAT2B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MAT2B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MAT2B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MAT2B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MAT2B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MAT2B gene:
Search GeneIP for patents involving MAT2B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MAT2B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MAT2B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MAT2B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAT2B | | | OriGene Protein Over-expression Lysate for MAT2B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MAT2B | | OriGene 3'-UTR Clone for MAT2B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAT2B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAT2B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MAT2B | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MAT2B | | OriGene Custom Protein Services for MAT2B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MAT2B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAT2B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAT2B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAT2B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAT2B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAT2B |
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| | | | Search Tocris compounds for MAT2B |
| |  |  |  |  | | | | | | Recombinant Protein for MAT2B |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAT2B |
|  |  |  | | | | ThermoFisher Antibodies for MAT2B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAT2B |
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