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Aliases for MAT2A Gene

Aliases for MAT2A Gene

  • Methionine Adenosyltransferase 2A 2 3 5
  • Methionine Adenosyltransferase II, Alpha 2 3
  • Methionine Adenosyltransferase 2 3 4
  • AdoMet Synthase 2 3 4
  • EC 2.5.1.6 4 56
  • MAT-II 3 4
  • MAT 2 3 4
  • MATA2 3 4
  • S-Adenosylmethionine Synthase Isoform Type-2 3
  • Methionine Adenosyltransferase II 4
  • Testicular Tissue Protein Li 121 3
  • AdoMet Synthetase 2 3
  • MATII 3
  • SAMS2 3
  • AMS2 4

External Ids for MAT2A Gene

Previous GeneCards Identifiers for MAT2A Gene

  • GC02P085661
  • GC02P086060
  • GC02P085740
  • GC02P085677
  • GC02P085619
  • GC02P085766
  • GC02P085663

Summaries for MAT2A Gene

Entrez Gene Summary for MAT2A Gene

  • The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011]

GeneCards Summary for MAT2A Gene

MAT2A (Methionine Adenosyltransferase 2A) is a Protein Coding gene. Diseases associated with MAT2A include Acute Maxillary Sinusitis and Glycine N-Methyltransferase Deficiency. Among its related pathways are Cytochrome P450 - arranged by substrate type and One carbon pool by folate. Gene Ontology (GO) annotations related to this gene include methionine adenosyltransferase activity. An important paralog of this gene is MAT1A.

UniProtKB/Swiss-Prot for MAT2A Gene

  • Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.

Additional gene information for MAT2A Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAT2A Gene

Genomics for MAT2A Gene

GeneHancer (GH) Regulatory Elements for MAT2A Gene

Promoters and enhancers for MAT2A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I085536 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 550.8 +0.8 782 6.9 MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 PARTICL PIR40998 PIR39955 MAT2A GC02M085541 SNORD94 USP39 C2orf68 LOC100996506 ELMOD3
GH02I085497 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 29.6 -39.1 -39095 4.7 HDGF PKNOX1 MLX ARNT ARID4B SIN3A DMAP1 POLR2B ZNF766 CBX5 MAT2A USP39 ELMOD3 SNORD94 RNU7-64P RN7SL251P CAPG TCF7L1 TMEM150A SH2D6
GH02I085885 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 12.4 +349.6 349557 5.2 HDGF PKNOX1 SMAD1 ARNT ARID4B SIN3A ZBTB7B YY1 ZNF766 CBX5 ST3GAL5 ST3GAL5-AS1 GC02M085889 GC02M085888 SNORD94 MAT2A TCF7L1 LOC284950 ELMOD3 RNU1-38P
GH02I085582 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 10.3 +45.9 45854 3.9 PKNOX1 FOXA2 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 IRF4 YY1 VAMP5 VAMP8 GGCX CAPG SH2D6 MAT2A ELMOD3 RETSAT USP39 RNF181
GH02I086440 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 10.1 +903.0 903047 3.6 CLOCK MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 KDM3A GC02M086437 SNORD94 LOC102724642 C2orf68 ENSG00000231259 LOC100420889 USP39 PTCD3 LOC105374845
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MAT2A on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the MAT2A gene promoter:

Genomic Locations for MAT2A Gene

Genomic Locations for MAT2A Gene
chr2:85,538,978-85,545,280
(GRCh38/hg38)
Size:
6,303 bases
Orientation:
Plus strand
chr2:85,766,101-85,772,403
(GRCh37/hg19)

Genomic View for MAT2A Gene

Genes around MAT2A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MAT2A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MAT2A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAT2A Gene

Proteins for MAT2A Gene

  • Protein details for MAT2A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P31153-METK2_HUMAN
    Recommended name:
    S-adenosylmethionine synthase isoform type-2
    Protein Accession:
    P31153
    Secondary Accessions:
    • A8K511
    • B4DN45
    • D6W5L1
    • Q53SP5

    Protein attributes for MAT2A Gene

    Size:
    395 amino acids
    Molecular mass:
    43661 Da
    Cofactor:
    Name=K(+); Xref=ChEBI:CHEBI:29103;
    Cofactor:
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
    Quaternary structure:
    • Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain (PubMed:10644686, PubMed:23189196). Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain (PubMed:25075345).
    Miscellaneous:
    • Protein expression is regulated by post-transcriptional regulation: in presence of S-adenosyl-L-methionine, METTL16 binds and methylates the first hairpin of the 3-UTR region of MAT2A mRNA, leading to intron retention and preventing MAT2A mRNA splicing (PubMed:28525753). In S-adenosyl-L-methionine-limiting conditions, METTL16 binds the 3-UTR region of MAT2A mRNA without methylting it due to the lack of a methyl donor, leading to stimulate splicing of the MAT2A retained intron, and promoting expression of MAT2A (PubMed:28525753).

    Three dimensional structures from OCA and Proteopedia for MAT2A Gene

    Alternative splice isoforms for MAT2A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MAT2A Gene

Selected DME Specific Peptides for MAT2A Gene

P31153:
  • GHPDKICD
  • AKVACETV
  • TGRKIIVDTYGG
  • IGAGDQG
  • PLSISIF
  • HGGGAFSGKD
  • FVIGGPQGD
  • AAYGHFGR
  • GRFVIGGP
  • DLDLKKPIY
  • LPWLRPD
  • QVSYAIG
  • GAGDQGLMFGYA
  • HIGYDDS
  • PIRVHTIVISVQHDEEVCLDEMRDALKEK
  • GLTGRKI
  • SYAIGVSHPLS
  • KGFDYKTCNVLVA
  • LFTSESV
  • QSPDIAQG
  • KTQVTVQY
  • VHLDRNEED
  • FTSESVGEGHPDK
  • DQISDAVLD
  • TKVDRSA
  • DYQKVVR
  • PAKYLDE
  • KTCNVLVALEQQSP
  • SDAVLDA
  • NFDLRPGVIV
  • MFGYATDET
  • LCRRVLVQVSY
  • CDQISDA
  • KVDRSAAY

Post-translational modifications for MAT2A Gene

  • Ubiquitination at isoforms=61, posLast=8181, posLast=9797, isoforms=2228, isoforms=2234, isoforms=2350, and posLast=367367

Other Protein References for MAT2A Gene

ENSEMBL proteins:
REFSEQ proteins:

Domains & Families for MAT2A Gene

Gene Families for MAT2A Gene

Human Protein Atlas (HPA):
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins

Suggested Antigen Peptide Sequences for MAT2A Gene

Graphical View of Domain Structure for InterPro Entry

P31153

UniProtKB/Swiss-Prot:

METK2_HUMAN :
  • Belongs to the AdoMet synthase family.
Family:
  • Belongs to the AdoMet synthase family.
genes like me logo Genes that share domains with MAT2A: view

Function for MAT2A Gene

Molecular function for MAT2A Gene

GENATLAS Biochemistry:
methionine adenosyltransferase,extrahepatic isoform,catalytic specific,subunit alpha,expressed in fetal liver,brain,testis,kidney,lymphocytes,sulfur aminoacid metabolism
UniProtKB/Swiss-Prot CatalyticActivity:
ATP + L-methionine + H(2)O = phosphate + diphosphate + S-adenosyl-L-methionine.
UniProtKB/Swiss-Prot Function:
Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.

Enzyme Numbers (IUBMB) for MAT2A Gene

Phenotypes From GWAS Catalog for MAT2A Gene

Gene Ontology (GO) - Molecular Function for MAT2A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004478 methionine adenosyltransferase activity IDA 7665609
GO:0005515 protein binding IPI 10644686
GO:0005524 ATP binding IEA --
GO:0016740 transferase activity IEA --
GO:0042802 identical protein binding IPI 25416956
genes like me logo Genes that share ontologies with MAT2A: view
genes like me logo Genes that share phenotypes with MAT2A: view

Animal Models for MAT2A Gene

MGI Knock Outs for MAT2A:

Animal Model Products

CRISPR Products

miRNA for MAT2A Gene

miRTarBase miRNAs that target MAT2A

Inhibitory RNA Products

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MAT2A Gene

Localization for MAT2A Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MAT2A gene
Compartment Confidence
cytosol 5
nucleus 3
mitochondrion 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for MAT2A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005829 cytosol IBA,TAS --
GO:0048269 methionine adenosyltransferase complex IDA 10644686
genes like me logo Genes that share ontologies with MAT2A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for MAT2A Gene

Pathways & Interactions for MAT2A Gene

genes like me logo Genes that share pathways with MAT2A: view

Pathways by source for MAT2A Gene

UniProtKB/Swiss-Prot P31153-METK2_HUMAN

  • Pathway: Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.

Gene Ontology (GO) - Biological Process for MAT2A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006556 S-adenosylmethionine biosynthetic process IDA,IEA --
GO:0006730 one-carbon metabolic process IEA --
GO:0032259 methylation TAS --
GO:0034214 protein hexamerization IDA 25075345
GO:0051291 protein heterooligomerization IDA 25075345
genes like me logo Genes that share ontologies with MAT2A: view

No data available for SIGNOR curated interactions for MAT2A Gene

Drugs & Compounds for MAT2A Gene

(9) Drugs for MAT2A Gene - From: DrugBank, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Ademetionine Approved, Investigational Nutra Target, cofactor 0
Phosphoric acid Approved Pharma 0
Potassium Approved, Investigational Pharma 0
Selenomethionine Approved, Investigational Pharma 0
Water Approved Pharma 0

(5) Additional Compounds for MAT2A Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
s-adenosylmethionine
  • (3S)-5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine
  • 2-S-Adenosyl-L-methionine
  • 5'-Deoxyadenosine-5'-L-methionine disulfate ditosylate
  • 5'-Deoxyadenosine-5'-L-methionine disulphate ditosylate
  • Active methionine
29908-03-0
L-Methionine
  • (2S)-2-amino-4-(methylsulfanyl)butanoate
  • (2S)-2-amino-4-(methylsulfanyl)butanoic acid
  • (L)-methionine
  • (S)-(+)-methionine
  • (S)-2-amino-4-(methylthio)-Butanoate
63-68-3
pyrophosphate
  • (4-)Diphosphoric acid ion
  • (P2O74-)Diphosphate
  • Diphosphate
  • Diphosphoric acid
  • PPi
14000-31-8
Se-Adenosylselenomethionine
genes like me logo Genes that share compounds with MAT2A: view

Transcripts for MAT2A Gene

Unigene Clusters for MAT2A Gene

Methionine adenosyltransferase II, alpha:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for MAT2A Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10
SP1: - - - - -
SP2: - - -
SP3: - -
SP4: - - -
SP5: -
SP6:
SP7:
SP8: -

Relevant External Links for MAT2A Gene

GeneLoc Exon Structure for
MAT2A
ECgene alternative splicing isoforms for
MAT2A

Expression for MAT2A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MAT2A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for MAT2A Gene



Protein tissue co-expression partners for MAT2A Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of MAT2A Gene:

MAT2A

SOURCE GeneReport for Unigene cluster for MAT2A Gene:

Hs.516157

mRNA Expression by UniProt/SwissProt for MAT2A Gene:

P31153-METK2_HUMAN
Tissue specificity: Detected in kidney.

Evidence on tissue expression from TISSUES for MAT2A Gene

  • Nervous system(5)
  • Kidney(4.8)
  • Lung(4.8)
  • Muscle(4.4)
  • Liver(3.8)
  • Skin(3.3)
  • Blood(3)
  • Stomach(3)
  • Intestine(2.9)
  • Eye(2.8)
  • Pancreas(2.5)
  • Thyroid gland(2.5)
  • Adrenal gland(2.3)
  • Gall bladder(2.2)
  • Heart(2)
genes like me logo Genes that share expression patterns with MAT2A: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for MAT2A Gene

Orthologs for MAT2A Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for MAT2A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MAT2A 34 33
  • 99.49 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MAT2A 34
  • 98 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MAT2A 34
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MAT2A 34 33
  • 95.02 (n)
OneToOne
cow
(Bos Taurus)
Mammalia MAT2A 34 33
  • 94.6 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mat2a 33
  • 93.5 (n)
mouse
(Mus musculus)
Mammalia Mat2a 33 16 34
  • 93.16 (n)
chicken
(Gallus gallus)
Aves -- 34
  • 72 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia MAT2A 34
  • 91 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia mat2a 33
  • 79.92 (n)
MGC76253 33
African clawed frog
(Xenopus laevis)
Amphibia m(2)21ab-prov 33
zebrafish
(Danio rerio)
Actinopterygii mat2aa 34
  • 92 (a)
OneToMany
mat2ab 34 33
  • 75.51 (n)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta M(2)21AB 35
  • 74 (a)
Sam-S 33 34
  • 67.71 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009447 33
  • 65.56 (n)
worm
(Caenorhabditis elegans)
Secernentea C06E7.1a 35
  • 74 (a)
sams-4 34
  • 68 (a)
ManyToMany
C49F5.1 35
  • 67 (a)
sams-5 34
  • 67 (a)
ManyToMany
sams-3 33 34
  • 66.67 (n)
sams-1 34
  • 63 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SAM2 34
  • 66 (a)
ManyToMany
SAM1 33 34
  • 63.51 (n)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0C01782g 33
  • 64.46 (n)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AFR692C 33
  • 60.67 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons MAT3 33
  • 63.23 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes sam1 33
  • 65.26 (n)
bread mold
(Neurospora crassa)
Ascomycetes NCU02657 33
  • 64.79 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10263 34
  • 63 (a)
OneToMany
Species where no ortholog for MAT2A was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MAT2A Gene

ENSEMBL:
Gene Tree for MAT2A (if available)
TreeFam:
Gene Tree for MAT2A (if available)

Paralogs for MAT2A Gene

Paralogs for MAT2A Gene

(1) SIMAP similar genes for MAT2A Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for MAT2A Gene

genes like me logo Genes that share paralogs with MAT2A: view

Variants for MAT2A Gene

Sequence variations from dbSNP and Humsavar for MAT2A Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs113066451 uncertain-significance, Vitamin K-Dependent Clotting Factors 85,545,372(+) C/T downstream_transcript_variant
rs115257622 benign, Thoracic aortic aneurysm and aortic dissection 85,541,099(+) A/G coding_sequence_variant, synonymous_variant
rs138686161 uncertain-significance, Vitamin K-Dependent Clotting Factors 85,545,355(+) C/T downstream_transcript_variant
rs142991697 likely-benign, Thoracic aortic aneurysm and aortic dissection 85,539,341(+) C/T coding_sequence_variant, synonymous_variant
rs143610695 benign, Thoracic aortic aneurysm and aortic dissection 85,541,861(+) T/C coding_sequence_variant, synonymous_variant

Structural Variations from Database of Genomic Variants (DGV) for MAT2A Gene

Variant ID Type Subtype PubMed ID
nsv2811 CNV insertion 18451855
nsv961801 CNV duplication 23825009

Variation tolerance for MAT2A Gene

Residual Variation Intolerance Score: 22.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.17; 3.89% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MAT2A Gene

Human Gene Mutation Database (HGMD)
MAT2A
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MAT2A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MAT2A Gene

Disorders for MAT2A Gene

MalaCards: The human disease database

(4) MalaCards diseases for MAT2A Gene - From: HGMD, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
acute maxillary sinusitis
  • acute antritis
glycine n-methyltransferase deficiency
  • gnmt deficiency
lymphocytic choriomeningitis
  • lcm
hypermethioninemia
  • mat deficiency
- elite association - COSMIC cancer census association via MalaCards
Search MAT2A in MalaCards View complete list of genes associated with diseases

Additional Disease Information for MAT2A

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with MAT2A: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MAT2A Gene

Publications for MAT2A Gene

  1. Role of methionine adenosyltransferase 2A and S-adenosylmethionine in mitogen-induced growth of human colon cancer cells. (PMID: 17631143) Chen H … Lu SC (Gastroenterology 2007) 3 22 25 58
  2. Cloning, expression, and functional characterization of the beta regulatory subunit of human methionine adenosyltransferase (MAT II). (PMID: 10644686) LeGros HL … Kotb M (The Journal of biological chemistry 2000) 3 4 22 58
  3. Cloning and functional characterization of the 5'-flanking region of human methionine adenosyltransferase 2A gene. (PMID: 9703951) Mao Z … Lu SC (Biochemical and biophysical research communications 1998) 2 3 22 58
  4. Molecular cloning and developmental expression of a human kidney S-adenosylmethionine synthetase. (PMID: 1426236) Horikawa S … Tsukada K (FEBS letters 1992) 2 3 4 58
  5. The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention. (PMID: 28525753) Pendleton KE … Conrad NK (Cell 2017) 3 4 58

Products for MAT2A Gene

Sources for MAT2A Gene

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