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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MAST1 Gene

protein-coding GIFtS: 52
GCID: GC19P012949

Microtubule Associated Serine/Threonine Kinase 1

5 related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Microtubule Associated Serine/Threonine Kinase 1¹ ²		SAST170²
SAST² ³ ⁵		Microtubule-Associated Serine/Threonine-Protein Kinase 1²
Syntrophin-Associated Serine/Threonine-Protein Kinase² ³		Syntrophin Associated Serine/Threonine Kinase²
EC 2.7.11.1³ ⁸		EC 2.7.11⁸
KIAA0973³ ⁵

External Ids:	HGNC: 19034¹	Entrez Gene: 22983²	Ensembl: ENSG00000105613⁷	OMIM: 612256⁵	UniProtKB: Q9Y2H9³

Export aliases for MAST1 gene to outside databases

Previous GC identifers: GC19U900423 GC19P012811 GC19P012520

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for MAST1 Gene:

MAST1 (microtubule associated serine/threonine kinase 1) is a protein-coding gene. Diseases associated with MAST1 include mastitis, and familial breast cancer. GO annotations related to this gene include protein serine/threonine kinase activity and magnesium ion binding. An important paralog of this gene is MAST2.

UniProtKB/Swiss-Prot: MAST1_HUMAN, Q9Y2H9

Function: Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins.

Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins (By similarity)

Gene Wiki entry for MAST1 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000019.9 NT_011295.11 NC_018930.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the MAST1 gene promoter:
c-Fos Spz1 AP-1 MZF-1 POU2F1 POU2F1a Chx10 c-Myb
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MAST1 promoter sequence

Search SABiosciences Chromatin IP Primers for MAST1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAST1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.2 Ensembl cytogenetic band: 19p13.2 HGNC cytogenetic band: 19p13.2

MAST1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAST1 gene location

GeneLoc information about chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P012949: view genomic region (about GC identifiers)

Start:	12,944,765 bp from pter	End:	12,985,766 bp from pter
Size:	41,002 bases	Orientation:	plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MAST1_HUMAN, Q9Y2H9 (See protein sequence)

Recommended Name: Microtubule-associated serine/threonine-protein kinase 1

Size: 1570 amino acids; 170677 Da

Cofactor: Magnesium (By similarity)

Subunit: Part of a low affinity complex that associates with, but is distinct from, the postsynaptic density. Interacts

with SNTB2 (By similarity)

Subcellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Cytoplasm,

cytoskeleton (By similarity). Note=Colocalizes with syntrophins at the cell membrane (By similarity)

Sequence caution: Sequence=AAB51171.1; Type=Erroneous gene model prediction; Sequence=AAH27985.2; Type=Erroneous

initiation; Sequence=BAA76817.1; Type=Erroneous initiation;

1 PDB 3D structure from and Proteopedia for MAST1:

3PS4 (3D)

Secondary accessions: O00114 Q8N6X0

Explore the universe of human proteins at neXtProt for MAST1: NX_Q9Y2H9

Explore proteomics data for MAST1 at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q9Y2H9

4/47 DME Specific Peptides for MAST1 (Q9Y2H9) (see all 47)

MFCSFET

RPRSRSL

KLTDFGL

SYRSTPD

MAST1 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_055790.1

ENSEMBL proteins:

ENSP00000466470 ENSP00000251472 ENSP00000465395 ENSP00000465187

Human Recombinant Protein Products for MAST1:

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	Novus Biologicals MAST1 Protein Novus Biologicals MAST1 Lysate
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	Cloud-Clone Corp. Proteins for MAST1

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005856	cytoskeleton	IEA	--
GO:0005886	plasma membrane	IEA	--
GO:0016020	membrane	--	--

MAST1 for ontologies About GeneDecksing

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

IUPHAR Guide to PHARMACOLOGY protein family classification: Microtubule associated serine/threonine kinase 1

MAST family

Other AGC kinases

5/8 InterPro protein domains (see all 8):

IPR002290 Ser/Thr_dual-sp_kinase_dom

IPR011009 Kinase-like_dom

IPR008271 Ser/Thr_kinase_AS

IPR015022 MA_Ser/Thr_Kinase_dom

IPR000719 Prot_kinase_cat_dom

Graphical View of Domain Structure for InterPro Entry Q9Y2H9

ProtoNet protein and cluster: Q9Y2H9

2 Blocks protein domains:

IPB000961 Protein kinase C-terminal domain

IPB001478 PDZ/DHR/GLGF domain

UniProtKB/Swiss-Prot: MAST1_HUMAN, Q9Y2H9

Similarity: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family

Similarity: Contains 1 AGC-kinase C-terminal domain

Similarity: Contains 1 PDZ (DHR) domain

Similarity: Contains 1 protein kinase domain

MAST1 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: MAST1_HUMAN, Q9Y2H9

Function: Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins.

Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins (By similarity)

Catalytic activity: ATP + a protein = ADP + a phosphoprotein

Enzyme Numbers (IUBMB): EC 2.7.11.1¹ ² EC 2.7.11²

Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000287	magnesium ion binding	ISS	--
GO:0004672	protein kinase activity	--	--
GO:0004674	protein serine/threonine kinase activity	ISS	--
GO:0004713	protein tyrosine kinase activity	--	--
GO:0005515	protein binding	IPI	--

MAST1 for ontologies About GeneDecksing

Phenotypes:
2 GenomeRNAi human phenotypes for MAST1:

Decreased substrate adherent c

Elongated cells

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for MAST1

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miRNA Products:
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		Browse SwitchGear 3'UTR luciferase reporter plasmids

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAST1

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MAST1

STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

5/37 Interacting proteins for MAST1 (Q9Y2H9^{1, 3} ENSP00000251472⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 37)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
EGFR	P00533¹^,³, ENSP00000275493⁴	EBI-3385920,EBI-297353 I2D: score=2 STRING: ENSP00000275493
ELAVL3	Q14576³, ENSP00000352162⁴	I2D: score=1 STRING: ENSP00000352162
PTEN	P60484³, ENSP00000361021⁴	I2D: score=1 STRING: ENSP00000361021
SNTB2	Q13425³, ENSP00000338191⁴	I2D: score=3 STRING: ENSP00000338191
SNTA1	Q13424³, ENSP00000217381⁴	I2D: score=1 STRING: ENSP00000217381

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006468	protein phosphorylation	ISS	--
GO:0007010	cytoskeleton organization	ISS	--
GO:0007243	intracellular protein kinase cascade	ISS	--

MAST1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, IUPHAR, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MAST1

3 HMDB Compounds for MAST1 About this table

Compound	Synonyms	CAS #	PubMed Ids
ADP	adenosindiphosphorsaeure (see all 8)	58-64-0	--
Adenosine triphosphate	5'-(tetrahydrogen triphosphate) Adenosine (see all 24)	56-65-5	--
Magnesium	Magnesium (see all 2)	7439-95-4	--

Search CenterWatch for drugs/clinical trials and news about MAST1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MAST1 gene:

NM_014975.2

Unigene Cluster for MAST1:

Microtubule associated serine/threonine kinase 1

Hs.227489 [show with all ESTs]

Unigene Representative Sequence: NM_014975

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000591495 ENST00000590883 ENST00000251472(uc002mvm.3 uc021upp.1)

ENST00000588379 ENST00000592713 ENST00000590204 ENST00000589040 ENST00000590553

ENST00000585791

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		4 QIAGEN miScript miRNA Assays for microRNAs that regulate MAST1:
		hsa-miR-493* hsa-let-7g* hsa-let-7a-2* hsa-miR-3924
		Browse SwitchGear 3'UTR luciferase reporter plasmids

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAST1

Additional mRNA sequence:

AB023190.1 AK297553.1 BC017485.1 BC026709.1 BC027985.1

4 DOTS entries:

DT.111657 DT.91644019 DT.97842203 DT.87046369

24/89 AceView cDNA sequences (see all 89):

BI913022 NM_014975 CR609181 BC017485 BU628948 AB023190 BQ929571 BQ638586

BQ222625 CA398145 BQ639245 CD251272 BC027985 CA398146 CR622253 BX279911

BU171055 BM726659 BM712892 BM668037 BI757317 BE539862 BQ721496 AL134803

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for MAST1 (see all 8) About this scheme

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7a	·	7b	·	7c	^	8	^	9a	·	9b	^	10	^	11	^	12a	·	12b	·	12c	^	13	^	14	^	15a	·	15b	^	16	^	17	^	18	^	19	^	20	^
SP1:													-				-																-
SP2:
SP3:
SP4:													-
SP5:																	-

ExUns:	21a	·	21b	^	22	^	23	^	24	^	25a	·	25b	^	26a	·	26b
SP1:	-										-
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for MAST1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MAST1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

See MAST1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MAST1

SOURCE GeneReport for Unigene cluster: Hs.227489

SABiosciences Custom PCR Arrays for MAST1

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals and fungi.

Orthologs for MAST1 gene from 6/13 species (see all 13) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Mast1^{1 , 5}	microtubule associated serine/threonine kinase 1^{1, 5}	85.99(n)¹ 94.52(a)¹		8 (41.32 cM)⁵ 56527¹ NM_019945.2¹ NP_064329.2¹ 84911903⁵
lizard (Anolis carolinensis)	Reptilia	MAST1⁶	Uncharacterized protein	76(a)	1 ↔ 1	2(28679735-28854064)
zebrafish (Danio rerio)	Actinopterygii	mast1¹	microtubule associated serine/threonine kinase 1	70.79(n) 79.56(a)		796739 XM_001337092.2 XP_001337128.2
fruit fly (Drosophila melanogaster)	Insecta	CG6498⁶	--	28(a)	1 → many	3L(15559113-15569413)
worm (Caenorhabditis elegans)	Secernentea	kin-4⁶	Protein KIN-4, isoform g	28(a)	possible ortholog	IV(11425742-11447065)
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	KIN82⁶ FPK1⁶	Putative serine/threonine protein kinase implicate... Ser/Thr protein kinase that regulates the putative...	25(a) 20(a)	many ↔ many many ↔ many	III(274404-276566) XIV(708523-711204)

ENSEMBL Gene Tree for MAST1 (if available)
TreeFam Gene Tree for MAST1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for MAST1 gene

MAST2² MAST3² MAST4²

18/27 SIMAP similar genes for MAST1 using alignment to 4 protein entries: MAST1_HUMAN (see all proteins) (see all similar genes):

MAST4 MAST3 STK38L RPS6KA2 RPS6KA3 MAST2

PRKACA SGK3 KIN27 PRKACB PRKACG PRKY

PRKX STK38 AKT1 AKT2 CIT AKT3

MAST1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
VAR_040769⁴		An ovarian serous carcinoma sample⁴	--	see VAR_040769	2	H Y	mis⁴		0	--	--	--	--
VAR_040768⁴		A metastatic melanoma sample⁴	--	see VAR_040768	2	A T	mis⁴		0	--	--	--	--
rs10424001^1,2	C,F,H	--	12948462(+)	`tgtttG/Aattta`	1	--	us2k¹		24		NS EA NA WA CSA	2351
rs35858668^1,2	C	--	12948572(+)	`GAAAC-/TTTTTT`	1	--	us2k¹		1		CSA	2
rs200709695^1,2	C	--	12948572(+)	`GAAACC/TTTTTT`	1	--	us2k¹		0	--	--	--	--
rs147681930^1,2		--	12948661(+)	`CAACCC/TCCCAA`	1	--	us2k¹		0	--	--	--	--
rs182061032^1,2		--	12948815(+)	`ACACAC/TGCTGA`	1	--	us2k¹		0	--	--	--	--
rs11883203^1,2	H	--	12948820(+)	`CGCTGA/GTATGC`	1	--	us2k¹		0	--	--	--	--
rs140720879^1,2		--	12948825(+)	`ATATGC/TCAACT`	1	--	us2k¹		0	--	--	--	--
rs77307303^1,2	C	--	12948837(+)	`ACTTGA/CCTTTA`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for MAST1 (12944765 - 12985766 bp)

Structural Variations
Database of Genomic Variants (DGV) 6 variations for MAST1: About this table

Variant ID	Type	Subtype	PubMed ID
esv2663622	CNV	Deletion	23128226
nsv2420	CNV	Insertion	18451855
nsv911082	CNV	Loss	21882294
nsv911084	CNV	Loss	21882294
nsv911083	CNV	Loss	21882294
dgv3733n71	CNV	Loss	21882294

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAST1

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

MAST1 for disorders           About GeneDecksing

OMIM gene information: 612256    OMIM disorders: --

5 diseases for MAST1:    About MalaCards

mastitis familial breast cancer rabies breast cancer

alzheimer's disease

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(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for MAST1 gene, integrated from 9 sources (see all 17):
(articles sorted by number of sources associating them with MAST1)

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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)^{1, 2} Grimwood J.... Lucas S.M. (2004)
Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)^{1, 2} Nagase T.... Ohara O. (1999)
Interactions between beta 2-syntrophin and a family of microtubule-associated serine/threonine kinases. (PubMed id 10404183)^{1, 9} Lumeng C....Chamberlain J.S. (1999)
Sast124, a novel splice variant of syntrophin-associated serine/threonine kinase (SAST), is specifically localized in the restricted brain regions. (PubMed id 12614677)^{1, 9} Yano R....Hashikawa T. (2003)
Interactome mapping suggests new mechanistic details u nderlying Alzheimer's disease. (PubMed id 21163940)¹ Soler-Lopez M....Aloy P. (2011)
Functionally recurrent rearrangements of the MAST kin ase and Notch gene families in breast cancer. (PubMed id 22101766)¹ Robinson D.R....Chinnaiyan A.M. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Regulation of epidermal growth factor receptor traffi cking by lysine deacetylase HDAC6. (PubMed id 20029029)¹ Deribe Y.L....Dikic I. (2009)
Patterns of somatic mutation in human cancer genomes. (PubMed id 17344846)² Greenman C.... Stratton M.R. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 22983	HGNC: 19034	AceView: MAST1	Ensembl:ENSG00000105613	euGenes: HUgn22983
ECgene: MAST1	H-InvDB: MAST1

(According to HUGE)
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HUGE: KIAA0973

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for MAST1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for MAST1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for MAST1 gene:
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Microtubule Associated Serine/Threonine Kinase 1

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Microtubule Associated Serine/Threonine Kinase 1

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