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Aliases & Descriptions for MAS1
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| MAS 2, 3 | | MGC119966 2 | | OTTHUMP00000017535 2 |
| | | Descriptions |
|---|
| MAS1 oncogene 2 |
|
| | Search outside databases for aliases for MAS1 genePrevious GC identifers: GC06P159767 GC06P160201 GC06P160237 |
Summaries for MAS1(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for MAS1: The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects. [provided by RefSeq] Gene Wiki entry for MAS1 |
Genomic Location for MAS1
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the MAS1 gene 
Entrez Gene cytogenetic band: 6q25.3-q26 Ensembl cytogenetic band: 6q25.3 HGNC cytogenetic band: 6q24-q27MAS1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P160298:
(about GC identifiers)
Start:
|
160,247,964 bp from pter |
End:
|
160,249,098 bp from pter |
Size:
|
1,135 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000006.10 NT_007422.13
| Proteins for MAS1
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: MAS_HUMAN, P04201 (See
protein sequence)Recommended Name: MAS proto-oncogene Size: 325 amino acids; 37465 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Caution: Was originally (PubMed:3419518) thought to be a receptor for angiotensin II
Secondary accessions: Q2TBC9 Q6FG47Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_002368.1
ENSEMBL proteins: ENSP00000252660
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
2 Gene Ontology (GO) cellular component terms (links to tree view): About this table
Antibodies for MAS1: Assays for MAS1: | Protein
Domains/ Families for MAS1(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry P04201
ProtoNet protein and cluster: P04201 1 Blocks protein family: IPB000820 Mas oncogene signature
UniProtKB/Swiss-Prot: MAS_HUMAN, P04201Similarity: Belongs to the G-protein coupled receptor 1 family | Gene Function for MAS1
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002377
Applied Biosystems Silencer® siRNAs for MAS1
Sigma-Aldrich siRNA and siRNA Panels for MAS1  Sigma-Aldrich shRNA Panels and shRNA for MAS1  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_002377                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_002377                                  untagged cDNA clone in CMV expression vector: NM_002377 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_002377
Genatlas biochemistry entry for MAS1:MAS1 oncogene (angiotensin receptor), G protein coupled receptor superfamily,imprinted in breast tissue2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Mas1):
3 Gene Ontology (GO) molecular function terms (links to tree view): About this table | Pathways & Interactions for MAS1
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
Gene Network CentralTM Interacting Genes and Proteins Network for MAS1 
5/8 Interacting proteins for MAS1 (ENSP000002526603) via UniProtKB, MINT, and/or STRING (see all 8
)About this table
4 Gene Ontology (GO) biological process terms (links to tree view): About this table
|
Drugs & Compounds for MAS1(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for MAS1
|
Transcripts for MAS1(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002377
Sigma-Aldrich siRNA and siRNA Panels for MAS1  Sigma-Aldrich shRNA Panels and shRNA for MAS1  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_002377 REFSEQ mRNAs for MAS1 gene: NM_002377.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_002377               OriGene GFP tagged cDNA clone in CMV expression vector: NM_002377                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_002377                                  untagged cDNA clone in CMV expression vector: NM_002377  Additional cDNA sequence: BC069142.1 BC069581.1 BC110454.2 CR542261.1 M13150.1 1 DOTS entry: DT.40119864 5 AceView cDNA sequences:NM_002377 BC069142 BC069581 M13150 CR542261
highest scoring ESTs for MAS1:M13150 BC069142 BC069581 CR542261 NM_002377 BC110454 CO915687 CO926509 CO930099 CO930118 Unigene Cluster for MAS1: MAS1 oncogene Hs.99900 [show with all ESTs]Unigene Representative Sequence: M13150
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000252660
|
Expression for MAS1
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| MAS1 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for MAS1
1 / 2 / 3 3 probe-sets matching MAS1 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: AGATACTAAT
SOURCE GeneReport for Unigene cluster: Hs.99900
Expression variation in blood from EXPOLDB for MAS1 |
Orthologs for MAS1
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for MAS1 gene from 5/6 species (see all 6
)
About this table Species with no ortholog for MAS1
ENSEMBL Gene Tree for MAS1 | Paralogs for MAS1(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for MAS1 gene
- MRGPRD2 MRGPRF2
|
SNPs/Variants for MAS1(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for MAS1 (up to first 250kb)
|
Disorders & Mutations for MAS1
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 165180
UniProtKB/Swiss-Prot: MAS_HUMAN, P04201
The MAS oncogene has a weak focus-inducing activity in transfected NIH 3T3 cellsHuman Genome Epidemiology Navigator: MAS1 (1 document) Tumor Gene Database: MAS1
|
Medical News for MAS1(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for MAS1 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/19 PubMed articles for MAS1 gene (see all 19
): |
Search for MAS1
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing MAS1
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing MAS1
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MAS1(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for MAS1(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for MAS1:

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| | Recombinant Proteins (MAS1) | | Antibodies (MAS1) |
| | | Search Tocris compounds for MAS1 |
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Incremental update: 13 Oct 2009
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