Aliases for MARS Gene
External Ids for MARS Gene
Previous GeneCards Identifiers for MARS Gene
This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules. [provided by RefSeq, Jan 2011]
GeneCards Summary for MARS Gene
MARS (Methionyl-TRNA Synthetase) is a Protein Coding gene. Diseases associated with MARS include Interstitial Lung And Liver Disease and Charcot-Marie-Tooth Disease, Axonal, Type 2U. Among its related pathways are Gene Expression and One carbon pool by folate. Gene Ontology (GO) annotations related to this gene include nucleotide binding and aminoacyl-tRNA ligase activity.
UniProtKB/Swiss-Prot for MARS Gene
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.