MARS Gene
protein-coding GIFtS: 67
GCID: GC12P057881
|
|
methionyl-tRNA synthetase
| |
Aliases
for MARS gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Methionyl-TRNA Synthetase1 2 3 | | MRS2 | | MetRS1 3 | | Cytosolic Methionyl-TRNA Synthetase2 | | EC 6.1.1.103 8 | | Methionine TRNA Ligase 1, Cytoplasmic2 | | METRS2 5 | | Methionine--TRNA Ligase, Cytoplasmic2 | | MTRNS2 5 | | |
Export aliases for MARS gene to outside databasesPrevious GC identifers: GC12M059209 GC12P058025 GC12P057598 GC12P056168 GC12P056167 GC12P054919 |
Summaries
for MARS gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MARS:
This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role inprotein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of themulti-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules. (provided by RefSeq, Jan2011)
Gene Wiki entry for MARS
|
Genomic Views
for MARS gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MARS gene promoter:
Spz1 Sox5 Elk-1 NF-1 CUTL1 GATA-1 GATA-2 PPAR-alpha c-Myb ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for MARS
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MARS |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q13 Ensembl cytogenetic band: 12q13.3 HGNC cytogenetic band: 12q13MARS Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P057881: view genomic region
(about GC identifiers)
Start:
|
57,869,228 bp from pter |
End:
|
57,911,352 bp from pter |
Size:
|
42,125 bases |
Orientation:
|
plus strand |
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Proteins
for MARS gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SYMC_HUMAN, P56192 (See
protein sequence)Recommended Name: Methionine--tRNA ligase, cytoplasmic Size: 900 amino acids; 101116 Da
Subunit: Component of the multisynthetase complex which is comprised of a bifunctional glutamyl-prolyl-tRNA synthetase,the monospecific isoleucyl, leucyl, glutaminyl, methionyl, lysyl, arginyl, and aspartyl-tRNA synthetases as well asthree auxiliary proteins, p18, p48 and p43
Subcellular location: Cytoplasm (Probable)
1 PDB 3D structure from  and Proteopedia  for MARS:2DJV (3D)
Secondary accessions: Q14895 Q53H14 Q96A15 Q96BZ0 Q9NSE0Explore the universe of human proteins at neXtProt for MARS: NX_P56192
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P56192
4/17 DME Specific Peptides for MARS (P56192) (see all 17)
MARS Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004981.2
ENSEMBL proteins: ENSP00000446168 ENSP00000262027 ENSP00000439307 ENSP00000447145 ENSP00000446729 ENSP00000447258 ENSP00000448576 ENSP00000450018 ENSP00000447914 ENSP00000449071 ENSP00000449787 ENSP00000448910 ENSP00000447335 ENSP00000448378 ENSP00000314653 Reactome Protein details: P56192
Human Recombinant Protein Products for MARS:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
MARS for ontologies About GeneDecksing
MARS Antibody Products:
Assay Products for MARS: |
Protein
Domains /
Families
for MARS gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MARS for domains About GeneDecksing
5/10 InterPro domains/families (see all 10):Graphical View of Domain Structure for InterPro Entry P56192ProtoNet protein and cluster: P56192 2 Blocks protein families: IPB002300 Aminoacyl-tRNA synthetase IPB002304 Methionyl-tRNA synthetase signature
UniProtKB/Swiss-Prot: SYMC_HUMAN, P56192Similarity: Belongs to the class-I aminoacyl-tRNA synthetase familySimilarity: Contains 1 GST C-terminal domainSimilarity: Contains 1 WHEP-TRS domain |
Function
for MARS gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: SYMC_HUMAN, P56192Catalytic activity: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met) Genatlas biochemistry entry for MARS:methionine tRNA synthetase
Enzyme Number (IUBMB): EC 6.1.1.101 2
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
MARS for ontologies About GeneDecksing
Phenotypes:
2 GenomeRNAi human phenotypes for MARS:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MARS (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MARS
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MARS (NM_004990) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MARS | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MARS |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MARS |
|
Pathways & Interactions
for MARS gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | tRNA Aminoacylation | | | 2 | Methionine metabolism | | | 3 | Selenocompound metabolism | | | 4 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for MARS
1  GeneGo (Thomson Reuters) Pathway for MARS
3 
Reactome Pathways for MARS
2 
Kegg Pathways (Kegg details for MARS):
MARS for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MARS
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/134 Interacting proteins for MARS (P561921, 2, 3 ENSP000002620274) via UniProtKB, MINT, STRING, and/or I2D (see all 134)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006418 | tRNA aminoacylation for protein translation |
TAS | -- | | GO:0006431 | methionyl-tRNA aminoacylation |
IEA | -- | | GO:0010467 | gene expression |
TAS | -- |
MARS for ontologies About GeneDecksing
|
Drugs & Compounds
for MARS gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MARS for compounds About GeneDecksing
 Browse Tocris compounds for MARS
6 HMDB Compounds for MARS About this table
1 DrugBank Compound for MARS About this table
10/14 Novoseek chemical compound relationships for MARS gene (see all 14) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| homocysteine thiolactone |
91.7 |
4 |
8425610 (2), 12234471 (1), 10721911 (1) |
| methionyl adenylate |
87.6 |
4 |
10360737 (2), 16155581 (1) |
| aminoacyl-trna |
85.4 |
2 |
12440524 (1), 9548745 (1) |
| trna(met) |
82.1 |
2 |
1408786 (1) |
| anticodon |
77.9 |
6 |
1280807 (2), 16155581 (1), 1408786 (1), 17510965 (1) |
| trna |
77.6 |
39 |
1408786 (3), 11714285 (3), 11118226 (3), 11732605 (2) (see all 13) |
| methionine |
69.9 |
25 |
19837083 (4), 8679580 (2), 10884371 (1), 17327360 (1) (see all 10) |
| homocysteine |
67.6 |
22 |
14656026 (1), 16769724 (1), 10884371 (1), 16106241 (1) (see all 13) |
| lysine |
51.6 |
2 |
14656026 (1), 11686577 (1) |
| mgatp |
38.2 |
4 |
1555604 (3), 9129831 (1) |
Search CenterWatch for drugs/clinical trials and news about MARS / SYMC
|
Transcripts
for MARS gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MARS gene: NM_004990.3 Unigene Cluster for MARS: Methionyl-tRNA synthetase Hs.632707 [show with all ESTs]Unigene Representative Sequence: NM_00499018/33 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 33): ENST00000549133 ENST00000537638(uc001sof.1 uc010srp.1) ENST00000262027(uc001sog.3)
ENST00000548674 ENST00000550449 ENST00000546481 ENST00000545888(uc001soh.1)
ENST00000547062 ENST00000548714 ENST00000551842 ENST00000553162 ENST00000547501
ENST00000551431 ENST00000549074 ENST00000447721 ENST00000552007 ENST00000551892
ENST00000548146
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MARS (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MARS
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MARS (NM_004990) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MARS | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MARS |
Additional cDNA sequence: AK222767.1 AK290857.1 AK303349.1 BC002384.2 BC006328.2 BC011639.2 BC011849.2 BC015011.1 BC065187.1 BT007338.1 D84224.1 X94754.1 Z49216.1 24/56 DOTS entries (see all 56): DT.100640144 DT.97863484 DT.87078184 DT.100045496 DT.91780655 DT.95079534 DT.100804509 DT.102841106 DT.95259612 DT.102841118 DT.100687100 DT.121187536 DT.100687081 DT.121187578 DT.121187400 DT.100739314 DT.97810576 DT.100061021 DT.121187401 DT.100687079 DT.95193903 DT.100045484 DT.121187561 DT.121187588 24/901 AceView cDNA sequences (see all 901): AU121799 BM142224 AA298540 BQ059546 AA326719 BE250298 CF132484 BQ649820 BM843371 BM979515 BM750258 BP344587 CF131911 BM758135 BM464842 CB159088 BM742977 BG741785 BM709424 BM672306 BM758541 BG818546 BX415894 BQ013573
GeneLoc Exon Structure
5/18 Alternative Splicing Database (ASD) splice patterns (SP) for MARS (see all 18) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | · | 12c | ^ | 13 | ^ | 14a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 14b | ^ | 15a | · | 15b | · | 15c | ^ | 16 | ^ | 17a | · | 17b | · | 17c | ^ | 18 | ^ | 19a | · | 19b | ^ | 20 | ^ | 21a | · | 21b | · | 21c | ^ | 22a | · | 22b | ^ | 23 | ^ | 24a | · | 24b | ^ | 25a | · | 25b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MARS
|
Expression
for MARS gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MARS expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCCACGGTTA
About this image
See MARS Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MARS
SOURCE GeneReport for Unigene cluster: Hs.632707
SABiosciences Custom PCR Arrays for MARS
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MARS
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MARS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MARS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MARS | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MARS |
Orthologs
for MARS gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for MARS gene from 11/42 species (see all 42) About this table
ENSEMBL Gene Tree for MARS (if available)
TreeFam Gene Tree for MARS (if available) |
Paralogs
for MARS gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MARS gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MARS (57869228 - 57911352 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for MARS
2 CNVs: 58585 3891 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MARS |
|
Disorders
/ Diseases
for MARS gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MARS for disorders About GeneDecksing
OMIM gene information: 156560
OMIM disorders: --
13  diseases for MARS: About MalaCardsclostridium difficile hepatorenal syndrome hepatic encephalopathy appendicitis
vascular disease cholestasis homocysteine tuberculosis
breast cancer atherosclerosis hepatitis prostatitis
mycobacterium tuberculosis
2 diseases from the University of Copenhagen DISEASES database for MARS:Liver disease Voyeurism 1 Novoseek disease relationship for MARS gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tuberculosis |
0 |
3 |
9607323 (2), 10360737 (1) |
Human Genome Epidemiology (HuGE) Navigator: MARS (23 documents)
Export disorders for MARS gene to outside databases
|
Publications
for MARS gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MARS gene, integrated from 9 sources (see all 115):
(articles sorted by number of sources associating them with MARS) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- CHOP/GADD153 and methionyl-tRNA synthetase (MetRS) genes overlap in a conserved region that controls mRNA stability. (PubMed id 10448063)1, 3, 9 Ubeda M....Habener J.F. (1999)
- Cloning of a human cDNA encoding a protein with high homology to yeast methionyl-tRNA synthetase. (PubMed id 8921912)1, 2, 9 Lage H. and Dietel M. (1996)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The appended C-domain of human methionyl-tRNA synthetase has a tRNA-sequestering function. (PubMed id 11714285)1, 9 Kaminska M....Mirande M. (2001)
- Methionyl-tRNA synthetase. (PubMed id 11732605)1, 9 Deniziak M.A. and Barciszewski J. (2001)
- Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis. (PubMed id 10791971)1, 9 Ko Y.G....Kim S. (2000)
- Mutations in methylenetetrahydrofolate reductase or cystathionine beta-synthase gene, or a high-methionine diet, increase homocysteine thiolactone levels in humans and mice. (PubMed id 17327360)7, 9 Chwatko G....Jakubowski H. (2007)
- Pathophysiological consequences of homocysteine excess. (PubMed id 16702349)7, 9 Jakubowski H. (2006)
- Genetic dissection of protein-protein interactions in multi-tRNA synthetase complex. (PubMed id 10200289)1, 9 Rho S.B....Shiba K. (1999)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
|
External Searches for MARS gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MARS gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MARS gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MARS gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MARS | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MARS gene:
Search GeneIP for patents involving MARS
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for MARS gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MARS | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MARS | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MARS | | | OriGene Protein Over-expression Lysate for MARS | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MARS | | OriGene 3'-UTR Clone for MARS | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MARS | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MARS | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MARS | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MARS | | OriGene Custom Protein Services for MARS | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MARS | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MARS | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MARS | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MARS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MARS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MARS |
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| | | | Search Tocris compounds for MARS |
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 | | | MARS Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MARS |
|  |  |  |  | | | | ThermoFisher Antibodies for MARS |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MARS |
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