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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MARCH7 Gene

protein-coding   GIFtS: 51
GCID: GC02P160569

membrane-associated ring finger (C3HC4) 7, E3 ubiquitin...

(Previous names: axotrophin, membrane-associated ring finger (C3HC4) 7 )
(Previous symbol: AXOT)
  Search for MARCH7
in our new
 Human Malady Compendium 
Biological research products
for MARCH7
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Membrane-Associated Ring Finger (C3HC4) 7, E3 Ubiquitin Protein Ligase1 2     RING Finger Protein 1772 3
AXOT1 2 3     Membrane-Associated Ring Finger (C3HC4) 71
MARCH-VII1 2 3     AXO2
RNF1771 2 3     E3 Ubiquitin-Protein Ligase MARCH72
Axotrophin3     Axotrophin3
Membrane-Associated RING Finger Protein 72 3     EC 6.3.2.-3
Membrane-Associated RING-CH Protein VII2 3     EC 6.3.28

External Ids:    HGNC: 173931   Entrez Gene: 648442   Ensembl: ENSG000001365367   OMIM: 6133345   UniProtKB: Q9H9923   

Export aliases for MARCH7 gene to outside databases

Previous GC identifers: GC02P160395 GC02P160277 GC02P152452


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MARCH7:
MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add
ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport
between membrane compartments (Bartee et al., 2004 (PubMed 14722266)).(supplied by OMIM, Mar 2010)

UniProtKB/Swiss-Prot: MARH7_HUMAN, Q9H992
Function: E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases
accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the
ubiquitin to targeted substrates

Gene Wiki entry for MARCH7


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_005403.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MARCH7 gene promoter:
         POU2F2 (Oct-2.1)   Oct-B1   oct-B3   oct-B2   POU2F2   POU2F2C   POU2F1   FOXJ2 (long isoform)   POU2F1a   POU2F2B   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for MARCH7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MARCH7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q24.2   Ensembl cytogenetic band:  2q24.2   HGNC cytogenetic band: 2q24.2

MARCH7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MARCH7 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P160569:  view genomic region     (about GC identifiers)

Start:
160,569,000 bp from pter      End:
160,625,359 bp from pter
Size:
56,360 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MARH7_HUMAN, Q9H992 (See protein sequence)
Recommended Name: E3 ubiquitin-protein ligase MARCH7  
Size: 704 amino acids; 78051 Da
Secondary accessions: A8K9X1 D3DPB0 Q53GQ1 Q9BTR9

Explore the universe of human proteins at neXtProt for MARCH7: NX_Q9H992

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H992

  • 4/7 DME Specific Peptides for MARCH7 (Q9H992) (see all 7)
     PCKCTGS  SSTNHQLPS  ITVDIIPSGW  EEEGDLCRICQ 

    MARCH7 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_073737.1  
    ENSEMBL proteins: 
     ENSP00000386830   ENSP00000259050   ENSP00000392862   ENSP00000387238   ENSP00000391493  
     ENSP00000442992  

    Human Recombinant Protein Products: 
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    OriGene Custom Protein Services for MARCH7 
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    Novus Biologicals MARCH7 Protein
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for MARCH7


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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    MARCH7 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR013083 Znf_RING/FYVE/PHD
     IPR011016 Znf_RING-CH

    Graphical View of Domain Structure for InterPro Entry Q9H992

    ProtoNet protein and cluster: Q9H992

    1 Blocks protein family: IPB001841 Zn-finger

    UniProtKB/Swiss-Prot: MARH7_HUMAN, Q9H992
    Domain: The RING-CH-type zinc finger domain is required for E3 ligase activity
    Similarity: Contains 1 RING-CH-type zinc finger


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: MARH7_HUMAN, Q9H992
    Function: E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases
    accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the
    ubiquitin to targeted substrates

    Enzyme Numbers (IUBMB): EC 6.3.2.-1 EC 6.3.22

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MARCH7
    8/23 QIAGEN miScript miRNA Assays for microRNAs that regulate MARCH7 (see all 23):
    hsa-miR-549 hsa-miR-3910 hsa-miR-607 hsa-miR-137 hsa-miR-200a hsa-miR-139-5p hsa-miR-141 hsa-miR-144
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    OriGene shRNA RFP: MARCH7
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MARCH7

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--
    GO:0016874ligase activity IEA--


    MARCH7 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for MARCH7:
     Increased cell number in G1, a 

    Animal Models:
         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for March7):
     cellular  hematopoietic system  homeostasis/metabolism  immune system  nervous system 

    MARCH7 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    UniProtKB/Swiss-Prot: MARH7_HUMAN, Q9H992
    Pathway: Protein modification; protein ubiquitination

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MARCH7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/8 Interacting proteins for MARCH7 (Q9H9922, 3 ENSP000002590504) via UniProtKB, MINT, STRING, and/or I2D (see all 8)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    USP7Q930092, 3, ENSP000003435354MINT-2876080 I2D: score=3 STRING: ENSP00000343535
    UBE2NP610883, ENSP000003161764I2D: score=2 STRING: ENSP00000316176
    VAV2P527353, ENSP000003609164I2D: score=1 STRING: ENSP00000360916
    UBE2KP610863, ENSP000002614274I2D: score=1 STRING: ENSP00000261427
    RNF111ENSP000002881994STRING: ENSP00000288199
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016567protein ubiquitination IEA--


    MARCH7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MARCH7

    4 HMDB Compounds for MARCH7    About this table
    CompoundSynonyms CAS #PubMed Ids
    Adenosine monophosphate5'-AMP (see all 28)61-19-8--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Phosphoric acidacide phosphorique (FRENCH) (see all 20)7664-38-2--
    Pyrophosphate(4-)Diphosphoric acid ion (see all 10)14000-31-8--
    Search CenterWatch for drugs/clinical trials and news about MARCH7 / MARH7 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MARCH7 gene: 
    NM_022826.2  

    Unigene Cluster for MARCH7:

    Membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
    Hs.529272  [show with all ESTs]
    Unigene Representative Sequence: AK124225
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000409175 ENST00000259050(uc002uax.3 uc010foq.3 uc010zcn.2 uc010for.3 uc002uay.3)
    ENST00000421037 ENST00000473749 ENST00000409591 ENST00000461582 ENST00000420397
    ENST00000478396 ENST00000539065

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MARCH7
    8/23 QIAGEN miScript miRNA Assays for microRNAs that regulate MARCH7 (see all 23):
    hsa-miR-549 hsa-miR-3910 hsa-miR-607 hsa-miR-137 hsa-miR-200a hsa-miR-139-5p hsa-miR-141 hsa-miR-144
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MARCH7
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MARCH7

    Additional cDNA sequence: 

    AF086110.1 AK022973.1 AK023400.1 AK124225.1 AK222880.1 AK292836.1 AK299051.1 AK302347.1 
    AK310238.1 AK316382.1 AL050171.1 AL833651.1 BC003404.1 BC065014.1 CR627026.1 

    21 DOTS entries:

    DT.100818768  DT.416796  DT.417390  DT.100818769  DT.95314071  DT.91995208  DT.445618  DT.95314072 
    DT.120993604  DT.100818767  DT.100818763  DT.100736480  DT.200651  DT.120993701  DT.304006  DT.97775071 
    DT.100690645  DT.100717775  DT.120993595  DT.91837646  DT.95363255 

    24/273 AceView cDNA sequences (see all 273):

    AA767752 T30104 AW606918 BF438895 BM455904 BP363743 CB124525 BP359178 
    CK000186 BQ959357 BC065014 BE161220 AI375265 BU172197 BQ278179 BM982036 
    AI075953 AI478160 AI346531 AI452649 AA046405 AI282772 AL597638 AI309539 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for MARCH7 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12 ^ 13
    SP1:                                                                                                            
    SP2:                                                                                      -                     
    SP3:              -                                                                                             
    SP4:                                                                                                            
    SP5:                                -     -     -                                                               


    ECgene alternative splicing isoforms for MARCH7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MARCH7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TAATTTCTCA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See MARCH7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MARCH7

    SOURCE GeneReport for Unigene cluster: Hs.529272
        SABiosciences Expression via Pathway-Focused PCR Array including MARCH7: 
              Ubiquitin Ligases in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MARCH7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for MARCH7 gene from 4/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves MARCH71 membrane-associated ring finger (C3HC4) 7 72.82(n)
    68.83(a)
      424332  XM_422176.3  XP_422176.3 
    lizard
    (Anolis carolinensis)
    Reptilia MARCH76
    --
    64(a)
    1 ↔ 1
    GL343371.1(930738-949344)
    African clawed frog
    (Xenopus laevis)
    Amphibia BU913136.12   -- 78.93(n)    BU913136.1 
    zebrafish
    (Danio rerio)
    Actinopterygii march71 membrane-associated ring finger (C3HC4) 7 51.86(n)
    47.79(a)
      100136862  NM_001114580.2  NP_001108052.2 


    ENSEMBL Gene Tree for MARCH7 (if available)
    TreeFam Gene Tree for MARCH7 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MARCH7 gene
    MARCH102  
    2 SIMAP similar genes for MARCH7 using alignment to 5 protein entries:     MARH7_HUMAN (see all proteins):
    MARCH10    MARCH6

    MARCH7 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1080 NCBI SNPs in MARCH7 are shown (see all 1080    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1474069031,2
    --160567036(+) CAGCAC/TAGCAA 1 -- us2k10--------
    rs1396158971,2
    --160567076(+) AATTAC/TCTGAA 1 -- us2k10--------
    rs1157616481,2
    F,--160567099(+) AGAGAG/ATACAT 1 -- us2k11Minor allele frequency- A:0.02WA 118
    rs1453059091,2
    --160567225(+) ATACTC/TACTTT 1 -- us2k10--------
    rs38213001,2
    C,F,H,--160567230(-) ATTATA/GAAGTG 1 -- us2k1 tfbs327Minor allele frequency- G:0.36EA NS NA WA 4266
    rs1147592421,2
    --160567232(+) CTTTAT/CAATAT 1 -- us2k11Minor allele frequency- C:0.01NA 120
    rs754173801,2
    --160567377(+) TCTTAC/GCATAA 1 -- us2k10--------
    rs1808998841,2
    --160567445(+) TATTGA/GTGGTT 1 -- us2k10--------
    rs1396114341,2
    --160567447(+) TTGGTC/GGTTTA 1 -- us2k10--------
    rs19727081,2
    C,F,H,--160567510(+) TGACGC/TGTTAT 1 -- us2k1 tfbs331Minor allele frequency- T:0.10NS EA NA WA CSA 2783

    HapMap Linkage Disequilibrium report for MARCH7 (160569000 - 160625359 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for MARCH7
         1 CNV: 98033

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MARCH7
    DNA2.0 Custom Variant and Variant Library Synthesis for MARCH7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    MARCH7 for disorders           About MalaCards

    MARCH7 for disorders           About GeneDecksing

    OMIM gene information: 613334    OMIM disorders: --

    1 Novoseek disease relationship for MARCH7 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leukemia 56.1 4 16147533 (2), 17161353 (1), 17632414 (1)


    Export disorders for MARCH7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MARCH7 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with MARCH7)
        Utopia: connect your pdf to the dynamic
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    1. E2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell system. (PubMed id 16868077)1, 2, 9 Flierman D.... Chau V. (2006)
    2. Leukaemia inhibitory factor (LIF) is functionally linked to axotrophin and both LIF and axotrophin are linked to regulatory immune tolerance. (PubMed id 15670816)1, 2 Metcalfe S.M....Lyons G.E. (2005)
    3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins. (PubMed id 14722266)1, 3 Bartee E.... Frueh K. (2004)
    7. Evidence for functional inter-relationships between FOXP3, leukaemia inhibitory factor, and axotrophin/MARCH-7 in transplantation tolerance. (PubMed id 17161353)1, 9 Muthukumarana P.A....Metcalfe S.M. (2006)
    8. The E3 ligase axotrophin/MARCH-7: protein expression profiling of human tissues reveals links to adult stem cells. (PubMed id 19901269)1, 9 Szigyarto C.A....Metcalfe S.M. (2010)
    9. Systematic analysis of dimeric E3-RING interactions re veals increased combinatorial complexity in human ubiquitination networks. (PubMed id 22493164)1 Woodsmith J....Sanderson C.M. (2012)
    10. Ubiquitin-specific peptidase 9, X-linked (USP9X) modul ates activity of mammalian target of rapamycin (mTOR). (PubMed id 22544753)1 Agrawal P....Hughes R.E. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64844 HGNC: 17393 AceView: AXOT Ensembl:ENSG00000136536 euGenes: HUgn64844
    ECgene: MARCH7 H-InvDB: MARCH7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MARCH7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MARCH7 gene:
    Search GeneIP for patents involving MARCH7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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