Aliases for MARCH7 Gene
External Ids for MARCH7 Gene
Previous Symbols for MARCH7 Gene
MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 18.104.22.168). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Mar 2010]
GeneCards Summary for MARCH7 Gene
MARCH7 (Membrane-Associated Ring Finger (C3HC4) 7, E3 Ubiquitin Protein Ligase) is a Protein Coding gene. GO annotations related to this gene include ligase activity. An important paralog of this gene is MARCH10.
UniProtKB/Swiss-Prot for MARCH7 Gene
E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.