MARCH6 Gene
protein-coding GIFtS: 49
GCID: GC05P010353
|
|
membrane-associated ring finger (C3HC4) 6, E3 ubiquitin...(Previous name: membrane-associated ring finger (C3HC4) 6 )
| |
Aliases
for MARCH6 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Membrane-Associated Ring Finger (C3HC4) 6, E3 Ubiquitin Protein Ligase1 2 | | DOA102 5 | | TEB41 2 3 5 | | KIAA05973 5 | | MARCH-VI1 2 3 | | Membrane-Associated Ring Finger (C3HC4) 61 | | RNF1761 2 3 | | E3 Ubiquitin-Protein Ligase MARCH62 | | Doa10 Homolog2 3 | | Membrane-Associated RING-CH Finger Protein 62 | | Membrane-Associated RING Finger Protein 62 3 | | EC 6.3.2.-3 | | Membrane-Associated RING-CH Protein VI2 3 | | Protein TEB-43 | | RING Finger Protein 1762 3 | | |
Export aliases for MARCH6 gene to outside databasesPrevious GC identifer: GC05P010408 |
Summaries
for MARCH6 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MARCH6:
This gene encodes a member of a family of membrane-associated E3 ubiquitin ligases containing RING-CH-type zinc fingermotifs. Ubiquitination of type II deiodinase by the encoded protein is an important regulatory step in thyroid hormonesignalling. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.(provided by RefSeq, Jul 2012)
UniProtKB/Swiss-Prot: MARH6_HUMAN, O60337Function: E3 ubiquitin-protein ligase that promotes ubiquitination of DIO2, leading to its degradation. E3 ubiquitinligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transferthe ubiquitin to targeted substrates. May cooperate with UBE2G1
Gene Wiki entry for MARCH6
|
Genomic Views
for MARCH6 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_006576.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MARCH6 gene promoter:
FOXD3 CUTL1 Evi-1 Gfi-1 MEF-2A Cart-1 ZIC2/Zic2 aMEF-2 Zic3 Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for MARCH6
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MARCH6 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5p15.2 Ensembl cytogenetic band: 5p15.2 HGNC cytogenetic band: 5p15.2MARCH6 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P010353: view genomic region
(about GC identifiers)
Start:
|
10,353,815 bp from pter |
End:
|
10,435,491 bp from pter |
Size:
|
81,677 bases |
Orientation:
|
plus strand |
|
Proteins
for MARCH6 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MARH6_HUMAN, O60337 (See
protein sequence)Recommended Name: E3 ubiquitin-protein ligase MARCH6 Size: 910 amino acids; 102545 Da
Subunit: Interacts with DIO2
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
Sequence caution: Sequence=AAB66840.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=AAB66840.1; Type=Frameshift; Positions=381, 382, 383, 385, 391, 396, 418; Sequence=BAA25523.1; Type=Erroneousinitiation;
Secondary accessions: A5PKZ4 D3DTC8 O14670 Q86X77Explore the universe of human proteins at neXtProt for MARCH6: NX_O60337
Post-translational modifications:
Auto-ubiquitinated, which results in proteasomal degradation1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O60337
MARCH6 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001257589.1 NP_001257590.1 NP_005876.2
ENSEMBL proteins: ENSP00000414643 ENSP00000426000 ENSP00000425930 ENSP00000274140 ENSP00000424512
Human Recombinant Protein Products for MARCH6:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0030176 | integral to endoplasmic reticulum membrane |
IDA | 15673284 |
MARCH6 for ontologies About GeneDecksing
MARCH6 Antibody Products:
Assay Products for MARCH6: |
Protein
Domains /
Families
for MARCH6 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MARCH6 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O60337ProtoNet protein and cluster: O60337 2 Blocks protein families: IPB001841 Zn-finger IPB011016 RINGv
UniProtKB/Swiss-Prot: MARH6_HUMAN, O60337Domain: The RING-CH-type zinc finger domain is required for E3 ligase activitySimilarity: Contains 1 RING-CH-type zinc finger |
Function
for MARCH6 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: MARH6_HUMAN, O60337Function: E3 ubiquitin-protein ligase that promotes ubiquitination of DIO2, leading to its degradation. E3 ubiquitinligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transferthe ubiquitin to targeted substrates. May cooperate with UBE2G1 Enzyme Number (IUBMB): EC 6.3.2.-1
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
MARCH6 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MARCH6
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MARCH6
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for MARCH6 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MARCH6 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MARCH6 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MARCH6 |
|
Pathways & Interactions
for MARCH6 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Protein processing in endoplasmic reticulum | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for MARCH6):
UniProtKB/Swiss-Prot: MARH6_HUMAN, O60337Pathway: Protein modification; protein ubiquitination
MARCH6 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MARCH6
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/70 Interacting proteins for MARCH6 (O603373 ENSP000002741404) via UniProtKB, MINT, STRING, and/or I2D (see all 70)
About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
MARCH6 for ontologies About GeneDecksing
|
Drugs & Compounds
for MARCH6 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MARCH6
4 HMDB Compounds for MARCH6 About this table
Search CenterWatch for drugs/clinical trials and news about MARCH6 / MARH6
|
Transcripts
for MARCH6 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MARCH6 gene (3 alternative transcripts): NM_001270660.1 NM_001270661.1 NM_005885.3 Unigene Cluster for MARCH6: Membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase Hs.432862 [show with all ESTs]Unigene Representative Sequence: NM_00588513 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000449913 ENST00000502795 ENST00000511802(uc003jeu.1) ENST00000503788
ENST00000274140(uc003jet.1 uc011cmu.1 uc011cmv.1) ENST00000510872
ENST00000507863 ENST00000506131 ENST00000514961 ENST00000510792 ENST00000512449
ENST00000505253 ENST00000514312
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MARCH6
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MARCH6
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for MARCH6 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MARCH6 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MARCH6 |
Additional cDNA sequence: AB011169.1 AF009301.1 AF056433.1 AF056443.1 AK000970.1 AK056198.1 AK296585.1 AK299339.1 AK300034.1 AK314686.1 AL080234.1 BC013761.1 BC039293.1 BC046148.1 BC111494.1 BC136461.1 BC136462.1 BC142679.1 BC142694.1 U52827.1 24/30 DOTS entries (see all 30): DT.119034 DT.99952876 DT.445205 DT.100857110 DT.70102348 DT.120823752 DT.97846982 DT.100796722 DT.120823769 DT.120823828 DT.95153569 DT.95207519 DT.100640725 DT.40303889 DT.75184473 DT.92441774 DT.95153574 DT.100745545 DT.100796723 DT.100796724 DT.120823757 DT.120823781 DT.120823806 DT.86846100 24/569 AceView cDNA sequences (see all 569): AL699390 AI474291 BM753076 BM911544 BM673903 BU784002 BE326757 BM680785 AI659023 BU679739 BM762004 AA280316 BI962679 AI123755 AA191101 AA411327 AU130760 AI421468 BX953192 CR610863 BG288023 BE139591 BQ019112 BC013761
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for MARCH6 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 | ^ | 19a | · | 19b | ^ | 20 | ^ | 21 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 22 | ^ | 23a | · | 23b | ^ | 24 | ^ | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 |
|---|
|
| SP1: | | | - | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | |
| SP5: | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MARCH6
|
Expression
for MARCH6 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MARCH6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCCTTTTTTG
About this image
See MARCH6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MARCH6
SOURCE GeneReport for Unigene cluster: Hs.432862
UniProtKB/Swiss-Prot: MARH6_HUMAN, O60337Tissue specificity: Present in brain (at protein level)
SABiosciences Expression via Pathway-Focused PCR Array including MARCH6:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MARCH6
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MARCH6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MARCH6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MARCH6 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MARCH6 |
Orthologs
for MARCH6 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for MARCH6 gene from 9/30 species (see all 30) About this table
ENSEMBL Gene Tree for MARCH6 (if available)
TreeFam Gene Tree for MARCH6 (if available) |
Paralogs
for MARCH6 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MARCH6 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MARCH6 (10353815 - 10435491 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MARCH6: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MARCH6 |
|
Disorders
/ Diseases
for MARCH6 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 MARCH6 for disorders About MalaCards
MARCH6 for disorders About GeneDecksing
OMIM gene information: 613297
OMIM disorders: --
Export disorders for MARCH6 gene to outside databases
|
Publications
for MARCH6 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MARCH6 gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with MARCH6) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase. (PubMed id 19651899)1, 2 Zavacki A.M....Bianco A.C. (2009)
- Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI). (PubMed id 16373356)1, 2 Kreft S.G.... Hochstrasser M. (2006)
- TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum. (PubMed id 15673284)1, 2 Hassink G.... Wiertz E. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins. (PubMed id 14722266)1, 3 Bartee E.... Frueh K. (2004)
- A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation. (PubMed id 11641273)1, 2 Swanson R.... Hochstrasser M. (2001)
- Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)1, 2 Nagase T....Ohara O. (1998)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- A novel locus for body mass index on 5p15.2: a meta-an alysis of two genome-wide association studies. (PubMed id 22446040)1 Wang K.S....Callahan K. (2012)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for MARCH6 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MARCH6 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MARCH6 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing MARCH6 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MARCH6 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MARCH6 gene:
Search GeneIP for patents involving MARCH6
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MARCH6 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for MARCH6 | | OriGene shRNA RFP for MARCH6 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MARCH6 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MARCH6 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MARCH6 | | OriGene 3'-UTR Clone for MARCH6 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MARCH6 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MARCH6 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MARCH6 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MARCH6 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MARCH6 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MARCH6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MARCH6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MARCH6 |
| |
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| |  |  |  |  | | | | |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MARCH6 |
|  |  |  |  | | | | ThermoFisher Antibodies for MARCH6 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MARCH6 |
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