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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MARCH10 Gene

protein-coding   GIFtS: 49
GCID: GC17M060778

Membrane-Associated Ring Finger (C3HC4) 10, E3 Ubiquitin...

(Previous names: ring finger protein 190, membrane-associated ring finger...)
(Previous symbol: RNF190)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Membrane-Associated Ring Finger (C3HC4) 10, E3 Ubiquitin Protein
Ligase1 2
     MARCH-X2 3
RING Finger Protein 1901 2 3     Membrane-Associated Ring Finger (C3HC4) 101
RNF1901 2 3     Probable E3 Ubiquitin-Protein Ligase MARCH102
Membrane-Associated RING Finger Protein 102 3     EC 6.3.2.-3
Membrane-Associated RING-CH Protein X2 3     

External Ids:    HGNC: 266551   Entrez Gene: 1623332   Ensembl: ENSG000001738387   OMIM: 6133375   UniProtKB: Q8NA823   

Export aliases for MARCH10 gene to outside databases

Previous GC identifers: GC17M058134 GC17M056145


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MARCH10 Gene:
MARCH10 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add
ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport
between membrane compartments (Morokuma et al., 2007 (PubMed 17604280)).(supplied by OMIM, Apr 2010)

GeneCards Summary for MARCH10 Gene: 
MARCH10 (membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase) is a protein-coding gene. Diseases associated with MARCH10 include kidney disease. GO annotations related to this gene include zinc ion binding and ligase activity. An important paralog of this gene is MARCH7.

UniProtKB/Swiss-Prot: MARHA_HUMAN, Q8NA82
Function: E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2
ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted
substrates




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010783.15  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MARCH10 gene promoter:
         RORalpha1   AML1a   AP-2alpha isoform 2   AP-2alpha   Hlf   FOXL1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for MARCH10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MARCH10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q23.2   Ensembl cytogenetic band:  17q23.2   HGNC cytogenetic band: 17q23.3

MARCH10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MARCH10 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M060778:  view genomic region     (about GC identifiers)

Start:
60,778,675 bp from pter      End:
60,885,705 bp from pter
Size:
107,031 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MARHA_HUMAN, Q8NA82 (See protein sequence)
Recommended Name: Probable E3 ubiquitin-protein ligase MARCH10  
Size: 808 amino acids; 90511 Da
Sequence caution: Sequence=AAH35021.1; Type=Erroneous termination; Positions=658; Note=Translated as Leu;
Sequence=BAC05079.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: D3DU09 Q8IYS7 Q8N7Z7

Explore the universe of human proteins at neXtProt for MARCH10: NX_Q8NA82

Explore proteomics data for MARCH10 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8NA82

  • MARCH10 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MARCH10 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001094345.1  NP_689811.2  

    ENSEMBL proteins: 
     ENSP00000463207   ENSP00000464220   ENSP00000416177   ENSP00000311496   ENSP00000463080  
     ENSP00000443746   ENSP00000463572   ENSP00000463029  

    Human Recombinant Protein Products for MARCH10: 
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    Browse R&D Systems for human recombinant proteins
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    OriGene Protein Over-expression Lysate for MARCH10
    OriGene Custom MassSpec 
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    Novus Biologicals MARCH10 Proteins
    Novus Biologicals MARCH10 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 


    MARCH10 Antibody Products: 
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    Abcam antibodies for MARCH10
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    Assay Products for MARCH10: 
    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RNF: RING-type (C3HC4) zinc fingers
    MARCH: MARCH membrane-associated ring fingers

    2 InterPro protein domains:
     IPR013083 Znf_RING/FYVE/PHD
     IPR011016 Znf_RING-CH

    Graphical View of Domain Structure for InterPro Entry Q8NA82

    ProtoNet protein and cluster: Q8NA82

    1 Blocks protein domain: IPB001841 Zn-finger

    UniProtKB/Swiss-Prot: MARHA_HUMAN, Q8NA82
    Domain: The RING-CH-type zinc finger domain is required for E3 ligase activity (By similarity)
    Similarity: Contains 1 RING-CH-type zinc finger


    MARCH10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MARHA_HUMAN, Q8NA82
    Function: E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2
    ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted
    substrates

         Enzyme Number (IUBMB): EC 6.3.2.-1

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--
    GO:0016874ligase activity IEA--
    GO:0046872metal ion binding ----
         
    MARCH10 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for MARCH10:
     Large cells 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MARCH10 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MARCH10

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MARCH10 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MARCH10 

    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate MARCH10:
    hsa-miR-1321 hsa-miR-222* hsa-miR-583
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    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MARCH10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MARCH10
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MARCH10


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    UniProtKB/Swiss-Prot: MARHA_HUMAN, Q8NA82
    Pathway: Protein modification; protein ubiquitination

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MARCH10

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for MARCH10 (Q8NA822, 3 ENSP000003114964) via UniProtKB, MINT, STRING, and/or I2D

    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBE2HP622563, ENSP000003478364I2D: score=2 STRING: ENSP00000347836
    --P310162MINT-8105979
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016567protein ubiquitination IEA--

    MARCH10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MARCH10 (MARHA)

    4 HMDB Compounds for MARCH10    About this table
    CompoundSynonyms CAS #PubMed Ids
    Adenosine monophosphate5'-AMP (see all 28)61-19-8--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Phosphoric acidacide phosphorique (FRENCH) (see all 20)7664-38-2--
    Pyrophosphate(4-)Diphosphoric acid ion (see all 10)14000-31-8--

    Search CenterWatch for drugs/clinical trials and news about MARCH10 / MARHA

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MARCH10 gene (2 alternative transcripts): 
    NM_001100875.1  NM_152598.2  

    Unigene Cluster for MARCH10:

    Membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
    Hs.665663  [show with all ESTs]
    Unigene Representative Sequence: AK122947
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000582358 ENST00000579620 ENST00000580520 ENST00000456609(uc010ddr.3)
    ENST00000311269 ENST00000583600(uc002jag.4 uc010dds.3) ENST00000544856(uc002jah.2)
    ENST00000582568 ENST00000578346 ENST00000583803
    miRNA
    Products:
         
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate MARCH10:
    hsa-miR-1321 hsa-miR-222* hsa-miR-583
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MARCH10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MARCH10
    Sirion Biotech Customized lentivirus for stable overexpression of MARCH10 
                         Customized lentivirus expression plasmids for stable overexpression of MARCH10 
    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MARCH10

    Additional mRNA sequence: 

    AK093076.1 AK097506.1 AK122947.1 BC035021.1 BX648705.1 

    6 DOTS entries:

    DT.92415232  DT.100743063  DT.101978959  DT.99989849  DT.91665499  DT.40307114 

    24/32 AceView cDNA sequences (see all 32):

    AK122947 AA884615 BX105355 AI262871 AI418361 NM_152598 AX747906 AI148036 
    AW274501 AW138484 AI911418 AI285835 AK097506 AI001159 AK093076 AW473122 
    BX106388 BX091948 BC035021 BX648705 AI797742 AW269755 AI819206 AW024402 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for MARCH10 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16a · 16b
    SP1:                          -     -                 -                                                     -     -               
    SP2:                          -     -                 -           -                                         -     -               
    SP3:                          -                       -           -                                                               
    SP4:                                -                 -           -                                                               
    SP5:                          -     -                                                                                             


    ECgene alternative splicing isoforms for MARCH10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MARCH10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATTCATTCA
    MARCH10 Expression
    About this image


    See MARCH10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MARCH10

    SOURCE GeneReport for Unigene cluster: Hs.665663
        SABiosciences Custom PCR Arrays for MARCH10
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MARCH10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for MARCH10 gene from 2/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia March101 , 5 membrane-associated ring finger (C3HC4) 101, 5 75.7(n)1
    64.19(a)1
      11 (68.73 cM)5
    6326871  NM_172568.21  NP_766156.21 
     1053607985 
    lizard
    (Anolis carolinensis)
    Reptilia MARCH106
    membrane-associated ring finger (C3HC4) 10, E3 ubi...
    38(a)
    1 ↔ 1
    6(61587386-61627026)


    ENSEMBL Gene Tree for MARCH10 (if available)
    TreeFam Gene Tree for MARCH10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MARCH10 gene
    MARCH72  
    3 SIMAP similar genes for MARCH10 using alignment to 7 protein entries:     MARHA_HUMAN (see all proteins):
    MARCH7    MARCH6    MARCH1

    MARCH10 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2280 SNPs in MARCH10 are shown (see all 2280)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs30346221,2
    C,H--56251628(+) aaaaaA/Taataa 2 -- int10--------
    rs1875412481,2
    --60778236(+) TCCTCA/GGCTTC 2 -- int10--------
    rs564140581,2
    C--60778320(+) TTTTTA/TAAACA 2 -- int14Minor allele frequency- T:0.12WA NA 8
    rs588369761,2
    C--60778330(+) AAAAA-/CACACA 2 -- int10--------
    rs671534431,2
    C--60778330(+) AAAAAA/CACACA 2 -- int11Minor allele frequency- C:0.00NA 2
    rs285626431,2
    --60778332(+) AAACAC/AACACA 2 -- int11Minor allele frequency- A:0.00NA 2
    rs607554151,2
    C--60778332(+) AAACA-/CACACA 2 -- int10--------
    rs1998172771,2
    C--60778338(+) ACACAA/CACACA 2 -- int10--------
    rs3694921921,2
    C--60778338(+) CACAC-/ACACG 
     TACTCAA
    ACACA
    4 -- int1 cds10--------
    rs728382711,2
    C--60778345(+) CACACT/ACGTAC 2 -- int11Minor allele frequency- A:0.50NA 2

    HapMap Linkage Disequilibrium report for MARCH10 (60778675 - 60885705 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for MARCH10:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2658945CNV Deletion23128226
    esv2666912CNV Deletion23128226
    nsv2115CNV Insertion18451855
    nsv509665CNV Insertion20534489
    nsv908680CNV Loss21882294
    esv26867CNV Loss19812545
    nsv516921CNV Gain+Loss19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing MARCH10
    DNA2.0 Custom Variant and Variant Library Synthesis for MARCH10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 613337    OMIM disorders: --

    2 diseases for MARCH10:    About MalaCards
    kidney disease    


    MARCH10 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MARCH10
    Human Genome Epidemiology (HuGE) Navigator: MARCH10 (3 documents)

    Export disorders for MARCH10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MARCH10 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with MARCH10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)1, 4 Oguri M....Yamada Y. (2010)
    2. Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315)1, 4 Yoshida T....Yamada Y. (2010)
    3. Association of gene polymorphisms with chronic kidney disease in Japanese individuals. (PubMed id 19724895)1, 4 Yoshida T....Yamada Y. (2009)
    4. MARCH-XI, a novel transmembrane ubiquitin ligase implicated in ubiquitin-dependent protein sorting in developing spermatids. (PubMed id 17604280)1, 3 Morokuma Y....Hirose S. (2007)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    8. GWAS for discovery and replication of genetic loci as sociated with sudden cardiac arrest in patients with coronary artery disease. (PubMed id 21658281)1 Aouizerat B.E....Tseng Z.H. (2011)
    9. The SH3 domain of postsynaptic density 95 mediates inf lammatory pain through phosphatidylinositol-3-kinase recruitment. (PubMed id 20467438)1 Arbuckle M.I....Grant S.G. (2010)
    10. Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. (PubMed id 19549727)1 Markson G....Sanderson C.M. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 162333 HGNC: 26655 AceView: FLJ35757 Ensembl:ENSG00000173838 euGenes: HUgn162333
    ECgene: MARCH10 H-InvDB: MARCH10

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MARCH10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MARCH10 gene:
    Search GeneIP for patents involving MARCH10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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