Aliases for MARCH10 Gene
External Ids for MARCH10 Gene
Previous HGNC Symbols for MARCH10 Gene
Previous GeneCards Identifiers for MARCH10 Gene
MARCH10 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 220.127.116.11). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Morokuma et al., 2007 [PubMed 17604280]).[supplied by OMIM, Apr 2010]
GeneCards Summary for MARCH10 Gene
MARCH10 (Membrane-Associated Ring Finger (C3HC4) 10, E3 Ubiquitin Protein Ligase) is a Protein Coding gene. GO annotations related to this gene include ligase activity. An important paralog of this gene is MARCH7.
UniProtKB/Swiss-Prot for MARCH10 Gene
E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.