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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MARCH1 Gene

protein-coding   GIFtS: 45
GCID: GC04M164448

membrane-associated ring finger (C3HC4) 1, E3 ubiquitin...

(Previous name: membrane-associated ring finger (C3HC4) 1 )
  Search for MARCH1
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Biological research products
for MARCH1    

Aliases
for MARCH1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase1 2     FLJ206681
MARCH-I1 2 3     Membrane-Associated Ring Finger (C3HC4) 11
RNF1711 2 3     E3 Ubiquitin-Protein Ligase MARCH12
Membrane-Associated RING Finger Protein 12 3     EC 6.3.2.-3
Membrane-Associated RING-CH Protein I2 3     EC 6.3.28
RING Finger Protein 1712 3     

External Ids:    HGNC: 260771   Entrez Gene: 550162   Ensembl: ENSG000001454167   OMIM: 6133315   UniProtKB: Q8TCQ13   

Export aliases for MARCH1 gene to outside databases

Previous GC identifers: GC04M164806 GC04M164668 GC04M160199


Summaries
for MARCH1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for MARCH1:
MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add
ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport
between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC)
class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal
compartment (Bartee et al., 2004 (PubMed 14722266); Thibodeau et al., 2008 (PubMed 18389477); De Gassart et al., 2008
(PubMed 18305173)).(supplied by OMIM, Mar 2010)

UniProtKB/Swiss-Prot: MARH1_HUMAN, Q8TCQ1
Function: E3 ubiquitin-protein ligase that mediates ubiquitination of TFRC, CD86, FAS and MHC class II proteins, such
as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular
bodies. By constitutively ubiquitinating MHC class II proteins in immature dendritic cells, down-regulates their cell
surface localization thus sequestering them in the intracellular endosomal system




Genomic Views
for MARCH1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MARCH1 gene promoter:
         GR   HTF   GR-beta   LCR-F1   Nkx6-1   FOXJ2 (long isoform)   FOXJ2   GR-alpha   Pax-4a   En-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for MARCH1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MARCH1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q32.2   Ensembl cytogenetic band:  4q32.3   HGNC cytogenetic band: 4q32.2

MARCH1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MARCH1 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M164448:  view genomic region     (about GC identifiers)

Start:
 164,445,450 bp from pter      End:
 165,305,202 bp from pter
Size:
 859,753 bases      Orientation:
 minus strand

Proteins
for MARCH1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: MARH1_HUMAN, Q8TCQ1 (See protein sequence)
Recommended Name: E3 ubiquitin-protein ligase MARCH1  
Size: 289 amino acids; 32308 Da
Subcellular location: Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein (By similarity).
Lysosome membrane; Multi-pass membrane protein (By similarity). Cytoplasmic vesicle membrane; Multi-pass membrane
protein. Late endosome membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein.
Cell membrane; Multi-pass membrane protein
Developmental stage: During maturation of dendritic cells, expression is down-regulated and stabilizes MHC class II
proteins accumulate at the plasma membrane
Secondary accessions: D3DP29 Q9NWR0
Alternative splicing: 2 isoforms:  Q8TCQ1-1   Q8TCQ1-2   

Explore the universe of human proteins at neXtProt for MARCH1: NX_Q8TCQ1

Post-translational modifications:

  • Has a short half-life. Instability/short half-life permits rapid changes that allow efficient induction of antigen
    • presentation once antigen presenting cells, APCs, receive maturation signals. Small changes in protein levels
    significantly alter the cell surface display of MHC class II proteins (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8TCQ1

    • 4 DME Specific Peptides for MARCH1 (Q8TCQ1)
     RLKAYNRVI  QDICRICHCEGD  FIMETKLKPLRKWEKLQMT  LEWPFWTKLVVVAIGFTGGL 

    MARCH1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001159845.1  NP_060393.1  

    ENSEMBL proteins: 
     ENSP00000427223   ENSP00000421322   ENSP00000345676   ENSP00000424089   ENSP00000426731  
     ENSP00000274056  

    Human Recombinant Protein Products: 
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    Novus Biologicals MARCH1 Proteins
    Novus Biologicals MARCH1 Lysate
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    Browse ProSpec Recombinant Proteins
    Browse Proteins at Uscn

    Gene Ontology (GO): 5/11 cellular component terms (GO ID links to tree view) (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005764lysosome IDA14722266
    GO:0005765lysosomal membrane ISS--
    GO:0005768endosome IDA14722266
    GO:0005789endoplasmic reticulum membrane ISS--
    GO:0005794Golgi apparatus IEA--


    MARCH1 for ontologies           About GeneDecksing



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    Browse ELISAs and CLIAs at Uscn

    Protein Domains /
    Families
    for MARCH1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    MARCH1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR013083 Znf_RING/FYVE/PHD
     IPR011016 Znf_RING-CH

    Graphical View of Domain Structure for InterPro Entry Q8TCQ1

    ProtoNet protein and cluster: Q8TCQ1

    2 Blocks protein families:
    IPB001841 Zn-finger
    IPB011016 RINGv


    UniProtKB/Swiss-Prot: MARH1_HUMAN, Q8TCQ1
    Domain: The RING-CH-type zinc finger domain is required for E3 ligase activity (By similarity)
    Similarity: Contains 1 RING-CH-type zinc finger


    Function
    for MARCH1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: MARH1_HUMAN, Q8TCQ1
    Function: E3 ubiquitin-protein ligase that mediates ubiquitination of TFRC, CD86, FAS and MHC class II proteins, such
    as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular
    bodies. By constitutively ubiquitinating MHC class II proteins in immature dendritic cells, down-regulates their cell
    surface localization thus sequestering them in the intracellular endosomal system
    Induction: By IL10/interleukin-10

    Enzyme Numbers (IUBMB): EC 6.3.2.-1 EC 6.3.22

    miRNA
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    hsa-miR-411* hsa-miR-607 hsa-miR-300 hsa-miR-106a hsa-miR-218-1* hsa-miR-200a hsa-miR-519a hsa-miR-93
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004842ubiquitin-protein ligase activity IDA18389477
    GO:0008270zinc ion binding IEA--
    GO:0042287MHC protein binding IDA18389477


    MARCH1 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out March1tm1.1Sish for MARCH1
         2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for March1):
     hematopoietic system  immune system 

    MARCH1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for MARCH1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    UniProtKB/Swiss-Prot: MARH1_HUMAN, Q8TCQ1
    Pathway: Protein modification; protein ubiquitination

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MARCH1

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for MARCH1 (Q8TCQ13 ENSP000003456764) via UniProtKB, MINT, STRING, and/or I2D

    InteractantInteraction Details
    GeneCardExternal ID(s)
    CD86P420813, ENSP000003320494I2D: score=1 STRING: ENSP00000332049
    PPP2R1AP301533, ENSP000003248044I2D: score=1 STRING: ENSP00000324804
    PPP2R1BP301543, ENSP000003113444I2D: score=1 STRING: ENSP00000311344
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000209protein polyubiquitination IDA19117940
    GO:0002495antigen processing and presentation of peptide antigen via MHC class II IDA18389477
    GO:0006955immune response IDA18305173


    MARCH1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for MARCH1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MARCH1

    4 HMDB Compounds for MARCH1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Adenosine monophosphate5'-AMP (see all 28)61-19-8--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Phosphoric acidacide phosphorique (FRENCH) (see all 20)7664-38-2--
    Pyrophosphate(4-)Diphosphoric acid ion (see all 10)14000-31-8--
    Search CenterWatch for drugs/clinical trials and news about MARCH1 / MARH1 

    Transcripts
    for MARCH1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for MARCH1 gene (2 alternative transcripts): 
    NM_001166373.1  NM_017923.3  

    Unigene Cluster for MARCH1:

    Membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
    Hs.592804  [show with all ESTs]
    Unigene Representative Sequence: NM_001166373
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000503008 ENST00000514618 ENST00000339875 ENST00000510786 ENST00000512214
    ENST00000505517 ENST00000507270 ENST00000511245 ENST00000510696 ENST00000503104
    ENST00000508725 ENST00000505391 ENST00000515471 ENST00000510075 ENST00000274056(uc003iqr.2 uc003iqs.2)


    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MARCH1
    8/68 QIAGEN miScript miRNA Assays for microRNAs that regulate MARCH1 (see all 68):
    hsa-miR-411* hsa-miR-607 hsa-miR-300 hsa-miR-106a hsa-miR-218-1* hsa-miR-200a hsa-miR-519a hsa-miR-93
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene siRNA: MARCH1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MARCH1
    Clone
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    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MARCH1

    Additional cDNA sequence: 

    AK000675.1 AK025005.1 AK091335.1 AK289711.1 AK301408.1 AL713759.1 

    8 DOTS entries:

    DT.210821  DT.97808988  DT.95142810  DT.121271202  DT.121271248  DT.209084  DT.121271261  DT.97764850 

    1 AceView cDNA sequence:

    AW118953 

    GeneLoc Exon Structure


    Expression
    for MARCH1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MARCH1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    MARCH1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    EyeOuter Nuclear LayerMature Rod CellsPhotoreceptors, Retina
    Neural TubeTelencephalonNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See MARCH1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MARCH1

    SOURCE GeneReport for Unigene cluster: Hs.592804

    UniProtKB/Swiss-Prot: MARH1_HUMAN, Q8TCQ1
    Tissue specificity: Expressed in antigen presenting cells, APCs, located in lymph nodes and spleen. Also expressed in
    lung. Expression is high in follicular B-cells, moderate in dendritic cells and low in splenic T-cells

        SABiosciences Expression via Pathway-Focused PCR Array including MARCH1: 
              Ubiquitin Ligases in human mouse rat

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    In Situ
    Assay Products:     
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    Orthologs
    for MARCH1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for MARCH1 gene from 4/16 species (see all 16)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves MARCH11 membrane-associated ring finger (C3HC4) 1 83.45(n)
    90.21(a)    		   422420  XM_429957.3  XP_429957.3 
    lizard
    (Anolis carolinensis)    		 Reptilia MARCH16
    		 --
    		 86(a)
    		 1 ↔ 1
    		 5(125980667-126017348)
    zebrafish
    (Danio rerio)    		 Actinopterygii march16
    		 membrane-associated ring finger (C3HC4) 1
    		 34(a)
    		 possible ortholog
    		 1(18450403-18498254)
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG40806
    		 --
    		 16(a)
    		 1 → many
    		 3L(9379927-9392327)


    ENSEMBL Gene Tree for MARCH1 (if available)
    TreeFam Gene Tree for MARCH1 (if available) 

    Paralogs
    for MARCH1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MARCH1 gene
    MARCH82  MARCH32  MARCH112  MARCH42  MARCH22  MARCH92  
    4 SIMAP similar genes for MARCH1 using alignment to 4 protein entries:     MARH1_HUMAN (see all proteins):
    MARCH8    MARCH3    MARCH6    MARCH10

    MARCH1 for paralogs           About GeneDecksing



    Genomic Variants
    for MARCH1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 21 variations for MARCH1
         11 CNVs: 22875 10076 92519 98946 64010 64009 92520 92521 64007 64008 59179
         10 Indels: 62279 46548 40701 46549 12578 42756 27501 40700 12577 27502
    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MARCH1
    DNA2.0 Custom Variant and Variant Library Synthesis for MARCH1

    Disorders / Diseases
    for MARCH1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    MARCH1 for disorders           About MalaCards

    MARCH1 for disorders           About GeneDecksing

    OMIM gene information: 613331    OMIM disorders: --

    Human Genome Epidemiology (HuGE) Navigator: MARCH1 (1 document)

    Export disorders for MARCH1 gene to outside databases

    Publications
    for MARCH1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MARCH1 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with MARCH1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins. (PubMed id 14722266)1, 2, 3 Bartee E.... Frueh K. (2004)
    2. Interleukin-10-induced MARCH1 mediates intracellular sequestration of MHC class II in monocytes. (PubMed id 18389477)1, 2, 9 Thibodeau J....Steimle V. (2008)
    3. MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation. (PubMed id 18305173)1, 2, 9 De Gassart A....Gatti E. (2008)
    4. The HLA-DRalpha chain is modified by polyubiquitination. (PubMed id 19117940)1, 2 Lapaque N....Kelly A.P. (2009)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Autoregulation of MARCH1 expression by dimerization an d autoubiquitination. (PubMed id 22508929)1 Bourgeois-Daigneault M.C. and Thibodeau J. (2012)
    7. Ubiquitin-mediated regulation of CD86 protein express ion by the ubiquitin ligase membrane-associated RING-CH-1 (MARCH1). (PubMed id 21896490)1 Corcoran K....Lybarger L. (2011)
    8. MARCH ubiquitin ligases alter the itinerary of clathr in-independent cargo from recycling to degradation. (PubMed id 21757542)1 Eyster C.A....Donaldson J.G. (2011)
    9. Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia. (PubMed id 21490949)1 Sim X....Tai E.S. (2011)
    10. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)

    External Searches for MARCH1 gene

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    Genome Databases showing MARCH1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55016 HGNC: 26077 AceView: MARCH-I.1 Ensembl:ENSG00000145416 euGenes: HUgn55016
    ECgene: MARCH1 H-InvDB: MARCH1

    Other Databases showing MARCH1 gene

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    Specialized Databases showing MARCH1 gene

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    NameDescription
    PharmGKB entry for MARCH1 Pharmacogenomics, SNPs, Pathways

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