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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MARC2 Gene

protein-coding GIFtS: 47
GCID: GC01P220922

mitochondrial amidoxime reducing component 2

(Previous name: MOCO sulphurase C-terminal domain containing 2 )
(Previous symbol: MOSC2)

Search for MARC2
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Mitochondrial Amidoxime Reducing Component 2¹ ² ³		FLJ20605¹
MOSC2¹ ² ³		RP11-270A6.1²
MOCO Sulphurase C-Terminal Domain Containing 2¹ ²		MOSC Domain-Containing Protein 2, Mitochondrial²
Moco Sulfurase C-Terminal Domain-Containing Protein 2² ³		EC 1.-.-.-³
Molybdenum Cofactor Sulfurase C-Terminal Domain-Containing Protein 2² ³		MARC2¹

External Ids:	HGNC: 26064¹	Entrez Gene: 54996²	Ensembl: ENSG00000117791⁷	OMIM: 614127⁵	UniProtKB: Q969Z3³

Export aliases for MARC2 gene to outside databases

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MOSC2_HUMAN, Q969Z3

Function: As a component of the benzamidoxime prodrug-converting complex required to reduce N-hydroxylated prodrugs,

such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and

N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively

Gene Wiki entry for MARC2 (MOSC2)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_167186.1

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for MARC2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MARC2 promoter sequence

Search SABiosciences Chromatin IP Primers for MARC2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MARC2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q41 Ensembl cytogenetic band: 1q41 HGNC cytogenetic band: 1q41

MARC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MARC2 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P220922: view genomic region (about GC identifiers)

Start:	220,921,567 bp from pter	End:	220,958,150 bp from pter
Size:	36,584 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MOSC2_HUMAN, Q969Z3 (See protein sequence)

Recommended Name: MOSC domain-containing protein 2, mitochondrial precursor

Size: 335 amino acids; 38023 Da

Cofactor: Molybdenum (Probable)

Subunit: Component of a complex composed of cytochrome b5, NADH-cytochrome b5 reductase (CYB5R3) and MOSC2 (By

similarity)

Subcellular location: Mitochondrion outer membrane; Peripheral membrane protein. Peroxisome (By similarity)

Sequence caution: Sequence=BAA91287.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

Sequence=CAH70306.1; Type=Erroneous gene model prediction; Sequence=CAH71880.1; Type=Erroneous gene model prediction;

Secondary accessions: B2D0R5 D3DTB3 Q0JSK7 Q5VT67 Q5VXC7 Q7L317 Q9H066 Q9NWU0

Alternative splicing: 2 isoforms: Q969Z3-1 Q969Z3-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MARC2: NX_Q969Z3

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q969Z3

MARC2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_060368.2

ENSEMBL proteins:

ENSP00000435450 ENSP00000352266 ENSP00000355880 ENSP00000416442

Human Recombinant Protein Products for MARC2:

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	Uscn Proteins for MARC2

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005739	mitochondrion	ISS	--
GO:0005741	mitochondrial outer membrane	IEA	--
GO:0005743	mitochondrial inner membrane	IEA	--
GO:0005777	peroxisome	IEA	--

MARC2 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

MARC2 for domains About GeneDecksing

3 InterPro domains/families:

IPR005303 MOSC_N

IPR005302 MoCF_Sase_C

IPR011037 Pyrv_Knase-like_insert_dom

Graphical View of Domain Structure for InterPro Entry Q969Z3

ProtoNet protein and cluster: Q969Z3

1 Blocks protein family: IPB005302 MOSC domain

UniProtKB/Swiss-Prot: MOSC2_HUMAN, Q969Z3

Similarity: Contains 1 MOSC domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: MOSC2_HUMAN, Q969Z3

Function: As a component of the benzamidoxime prodrug-converting complex required to reduce N-hydroxylated prodrugs,

such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and

N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively

Biophysicochemical properties: Kinetic parameters: KM=830 uM for benzamidoxime; KM=3 mM for NOHA; KM=3.7 mM for NHAM;

Vmax=307 nmol/min/mg enzyme toward benzamidoxime; Vmax=373 nmol/min/mg enzyme toward NOHA; Vmax=36.5 nmol/min/mg

enzyme toward NHAM;

Enzyme Number (IUBMB): EC 1.-.-.-¹

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008940	nitrate reductase activity	IDA	--
GO:0030151	molybdenum ion binding	IDA	--
GO:0030170	pyridoxal phosphate binding	IEA	--
GO:0043546	molybdopterin cofactor binding	IDA	--

MARC2 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for MARC2:

Decreased circadian period len

6 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Marc2):

adipose tissue	behavior/neurological	growth/size	hematopoietic system	homeostasis/metabolism
immune system

MARC2 for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for MARC2

miRNA Products:		OriGene 3'-UTR Clone: MARC2 Browse MicroRNA Expression Plasmids
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MARC2

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MARC2

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

2 Interacting proteins for MARC2 (Q969Z3³ ENSP00000355880⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
YWHAB	P31946³	I2D: score=1
NDUFS2	ENSP00000356972⁴	STRING: ENSP00000356972

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0042126	nitrate metabolic process	IDA	--
GO:0051410	detoxification of nitrogen compound	NAS	--
GO:0055114	oxidation-reduction process	IDA	--

MARC2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MARC2
Search CenterWatch for drugs/clinical trials and news about MARC2 / MOSC2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MARC2 gene:

NM_017898.3

Unigene Cluster for MARC2:

Mitochondrial amidoxime reducing component 2

Hs.369042 [show with all ESTs]

Unigene Representative Sequence: AK125512

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000469583 ENST00000359316 ENST00000366913(uc001hmq.3 uc001hmr.3 uc009xdx.3)

ENST00000425560 ENST00000496078 ENST00000472447

miRNA Products:		OriGene 3'-UTR Clone: MARC2 Browse OriGene MicroRNA Expression Plasmids
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MARC2

Additional cDNA sequence:

AK000583.1 AK000612.1 AK125512.1 AL136931.1 BC010366.1 BC011973.1 BC015829.2 BC016859.1

5 DOTS entries:

DT.215529 DT.101958880 DT.92425176 DT.86840490 DT.92425177

24/144 AceView cDNA sequences (see all 144):

CB267441 AI580303 BQ889002 AI650791 AI473138 AA779383 AI912794 AA854382

AA649845 AI028136 BE046902 AI570738 BF222677 AA843271 AI247692 AI457991

AI283785 AI379634 BC011973 AI400354 AI422191 AI572411 CA394968 CA312814

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for MARC2 (see all 7) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3a	·	3b	^	4	^	5a	·	5b	^	6	^	7a	·	7b	·	7c	^	8	^	9	^	10a	·	10b	·	10c
SP1:									-												-		-				-
SP2:									-												-		-				-
SP3:																							-				-
SP4:							-		-
SP5:

ECgene alternative splicing isoforms for MARC2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MARC2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTATTACAC

About this image

MARC2 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Ovary

Antral Follicle

Mature Granulosa Cells

Ovary

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See MARC2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MARC2

SOURCE GeneReport for Unigene cluster: Hs.369042

SABiosciences Custom PCR Arrays for MARC2

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MARC2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the last universal common ancestor (LUCA).

Orthologs for MARC2 gene from 8/24 species (see all 24) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	MARC2¹	mitochondrial amidoxime reducing component 2	68.05(n) 62.42(a)		428563 XM_426119.2 XP_426119.2
lizard (Anolis carolinensis)	Reptilia	--	--	56(a)	1 → many	1(243573986-243585219)
zebrafish (Danio rerio)	Actinopterygii	zgc:110783¹	zgc:110783	55.7(n) 48.68(a)		378742 NM_001014367.1 NP_001014389.1
fruit fly (Drosophila melanogaster)	Insecta	CG1665⁶	--	26(a)	1 → many	2R(5727283-5728667)
worm (Caenorhabditis elegans)	Secernentea	F56A11.5⁶ F22B8.7⁶ (see all 3)	Protein F22B8.7 (see all 3)	31(a) 30(a) (see all 3)	many ↔ many many ↔ many (see all 3)	IV(568373-570843) V(16095204-16097300)
thale cress (Arabidopsis thaliana)	eudicotyledons	AT5G44720¹	molybdenum cofactor sulfurase family protein	45.98(n) 37.07(a)		834501 NM_123839.3 NP_199285.1
rice (Oryza sativa)	Liliopsida	Os09g0560800¹	hypothetical protein	45.11(n) 34.21(a)		4347854 NM_001070465.1 NP_001063930.1
E. coli (Escherichia coli)	Gamma proteobacteria	ycbX⁶	predicted 2Fe-2S cluster-containing protein; 6-N-h...	22(a)	1 → many	Chromosome(1005714-1006823)

ENSEMBL Gene Tree for MARC2 (if available)
TreeFam Gene Tree for MARC2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for MARC2 gene

MARC1² MOCOS²

1 SIMAP similar gene for MARC2 using alignment to 2 protein entries: MOSC2_HUMAN (see all proteins):

MARC1

MARC2 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for MARC2
PGOHUM00000237925

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs150564788^1,2		--	220919703(+)	`ACTCCC/TGCCAC`	1	--	us2k¹		0	--	--	--	--
rs74139892^1,2	C	--	220919809(+)	`TGCACG/ATGCTG`	1	--	us2k¹		2		WA	120
rs190612026^1,2		--	220919886(+)	`CCAAAC/GCTCCG`	1	--	us2k¹		0	--	--	--	--
rs12133663^1,2	C,F,A,H	--	220920083(+)	`AGGACG/AAAGCC`	1	--	us2k¹		14		NS EA NA	1182
rs72472364^1,2	C,F	--	220920305(+)	`ACACCA/CTGCTT`	1	--	us2k¹		7		NS NA	310
rs12738566^1,2	C,F	--	220920374(+)	`GGACTA/GATTCT`	1	--	us2k¹		8		NA NS	312
rs11800654^1,2	C,F,H	--	220920386(+)	`CTGGCC/TTGAGG`	1	--	us2k¹		7		NS NA WA	306
rs182964758^1,2		--	220920492(+)	`CTTCCC/TGGAGT`	1	--	us2k¹		0	--	--	--	--
rs72472365^1,2	C,F	--	220920518(+)	`AGAACG/CGGCCC`	1	--	us2k¹		9		NS NA WA EA	550
rs139544590^1,2		--	220920718(+)	`TGGAGG/TTGTTA`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for MARC2 (220921567 - 220958150 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MARC2: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MARC2

DNA2.0 Custom Variant and Variant Library Synthesis for MARC2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

MARC2 for disorders About MalaCards

MARC2 for disorders About GeneDecksing

OMIM gene information: 614127 OMIM disorders: --

Export disorders for MARC2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MARC2 gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with MARC2)

Utopia: connect your pdf to the dynamic
world of online information

Reduction of N(I8)-hydroxy-L-arginine by the mitochond rial amidoxime reducing component (mARC). (PubMed id 21029045)^{1, 2} Kotthaus J....Clement B. (2010)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
MOSC domains: ancient, predicted sulfur-carrier domains, present in diverse metal-sulfur cluster biosynthesis proteins including Molybdenum cofactor sulfurases. (PubMed id 11886751)^{1, 3} Anantharaman V. and Aravind L. (2002)
Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)^{1, 2} Wiemann S.... Poustka A. (2001)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
Structural studies of the molybdenum center of mitoch ondrial amidoxime reducing component (mARC) by pulsed EPR spectroscopy and 17O- labeling. (PubMed id 21916412)¹ Rajapakshe A....Enemark J.H. (2011)
The Chlamydomonas reinhardtii molybdenum cofactor enz yme crARC has a Zn-dependent activity and protein partners similar to those of its human homologue. (PubMed id 21803866)¹ Chamizo-Ampudia A....Llamas A. (2011)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 54996	HGNC: 26064	AceView: FLJ20605	Ensembl:ENSG00000117791	euGenes: HUgn54996
ECgene: MARC2	H-InvDB: MARC2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for MARC2	Pharmacogenomics, SNPs, Pathways
NIEHS-SNPs	http://egp.gs.washington.edu/data/mosc2/

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Patent Information for MARC2 gene:
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mitochondrial amidoxime reducing component 2

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mitochondrial amidoxime reducing component 2

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