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MARC1 Gene

protein-coding   GIFtS: 44
GCID: GC01P220961

Mitochondrial Amidoxime Reducing Component 1

(Previous name: MOCO sulphurase C-terminal domain containing 1)
(Previous symbol: MOSC1)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Mitochondrial Amidoxime Reducing Component 11 2 3     Molybdenum Cofactor Sulfurase C-Terminal Domain-Containing Protein 12 3
MOSC11 2 3 5     MOSC Domain-Containing Protein 1, Mitochondrial2
MOCO Sulphurase C-Terminal Domain Containing 11 2     EC 1.-.-.-3
Moco Sulfurase C-Terminal Domain-Containing Protein 12 3     mARC13

External Ids:    HGNC: 261891   Entrez Gene: 647572   Ensembl: ENSG000001862057   OMIM: 6141265   UniProtKB: Q5VT663   

Export aliases for MARC1 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MARC1 Gene:
MARC1 (mitochondrial amidoxime reducing component 1) is a protein-coding gene. Diseases associated with MARC1 include malaria. GO annotations related to this gene include molybdenum ion binding and pyridoxal phosphate binding. An important paralog of this gene is MARC2.

UniProtKB/Swiss-Prot: MOSC1_HUMAN, Q5VT66
Function: As a component of an N-hydroxylated prodrug-converting complex required to reduce N-hydroxylated
prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and
N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NC_018912.2  NT_004487.20  
Regulatory elements:
   Search for regulatory transcription factor binding sites for MARC1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMARC1 promoter sequence
   Search Chromatin IP Primers for MARC1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MARC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q41   Ensembl cytogenetic band:  1q41   HGNC cytogenetic band: 1q41

MARC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MARC1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P220961:  view genomic region     (about GC identifiers)

Start:
220,960,039 bp from pter      End:
220,987,741 bp from pter
Size:
27,703 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MOSC1_HUMAN, Q5VT66 (See protein sequence)
Recommended Name: MOSC domain-containing protein 1, mitochondrial  
Size: 337 amino acids; 37499 Da
Cofactor: Molybdenum
Subunit: Component of a complex composed of cytochrome b5, NADH-cytochrome b5 reductase and MOSC1
Sequence caution: Sequence=BAB15333.1; Type=Frameshift; Positions=139; Sequence=CAH72118.1; Type=Erroneous gene
model prediction;
Secondary accessions: A8K447 B2D078 Q5VVS9 Q5VVT0 Q5VVT1 Q8N9P5 Q96FN8 Q9H6C7
Alternative splicing: 3 isoforms:  Q5VT66-1   Q5VT66-2   Q5VT66-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MARC1: NX_Q5VT66

Explore proteomics data for MARC1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys310
  • Modification sites at PhosphoSitePlus

  • See MARC1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_073583.3  
    ENSEMBL proteins: 
     ENSP00000355877   ENSP00000385327   ENSP00000434522   ENSP00000409634  

    MARC1 Human Recombinant Protein Products:

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    Novus Biologicals MARC1 Lysate
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    Browse Proteins at Cloud-Clone Corp.

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    MARC1 Assay Products:

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    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR005303 MOSC_N
     IPR005302 MoCF_Sase_C
     IPR011037 Pyrv_Knase-like_insert_dom

    Graphical View of Domain Structure for InterPro Entry Q5VT66

    ProtoNet protein and cluster: Q5VT66

    UniProtKB/Swiss-Prot: MOSC1_HUMAN, Q5VT66
    Similarity: Contains 1 MOSC domain


    MARC1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MOSC1_HUMAN, Q5VT66
    Function: As a component of an N-hydroxylated prodrug-converting complex required to reduce N-hydroxylated
    prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and
    N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively
    Biophysicochemical properties: Kinetic parameters: KM=180 uM for benzamidoxime; KM=86 uM for NOHA; KM=272 uM for
    NHAM; Vmax=34 nmol/min/mg enzyme toward benzamidoxime; Vmax=55 nmol/min/mg enzyme toward NOHA; Vmax=43
    nmol/min/mg enzyme toward NHAM;

         Enzyme Number (IUBMB): EC 1.-.-.-1

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0008940nitrate reductase activity IDA--
    GO:0030151molybdenum ion binding IDA--
    GO:0030170pyridoxal phosphate binding IEA--
    GO:0043546molybdopterin cofactor binding IDA--
         
    MARC1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MARC1
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    miRNA
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    miRTarBase miRNAs that target MARC1:
    hsa-mir-155-5p (MIRT001536), hsa-mir-100-5p (MIRT048573)

    Block miRNA regulation of human, mouse, rat MARC1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate MARC1
    SwitchGear 3'UTR luciferase reporter plasmidMARC1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat MARC1

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MOSC1_HUMAN, Q5VT66: Mitochondrion outer membrane; Single-pass type II membrane protein. Note=Mitochondrial
    import is mediated by AA 1-40 and requires ATP

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ISS--
    GO:0005741mitochondrial outer membrane IEA--
    GO:0005743mitochondrial inner membrane IEA--
    GO:0016021integral component of membrane IEA--

    MARC1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MARC1
    Interactions:

        Search GeneGlobe Interaction Network for MARC1

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for MARC1 (Q5VT663 ENSP000003558774) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    NDUFS2ENSP000003569724STRING: ENSP00000356972
    NDUFS3ENSP000002637744STRING: ENSP00000263774
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0042126nitrate metabolic process IDA--
    GO:0051410detoxification of nitrogen compound NAS--
    GO:0055114oxidation-reduction process IDA--

    MARC1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MARC1 (MOSC1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MARC1 gene: 
    NM_022746.3  

    Unigene Cluster for MARC1:

    Mitochondrial amidoxime reducing component 1
    Hs.497816  [show with all ESTs]
    Unigene Representative Sequence: AK092439
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000366910(uc001hms.3 uc001hmt.3) ENST00000492847 ENST00000407981
    ENST00000496110 ENST00000463976 ENST00000443880 ENST00000472269
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MARC1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate MARC1
    SwitchGear 3'UTR luciferase reporter plasmidMARC1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat MARC1
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    Primer
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    OriGene qPCR primer pairs and template standards for MARC1
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    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat MARC1
      QuantiTect SYBR Green Assays in human, mouse, rat MARC1
      QuantiFast Probe-based Assays in human, mouse, rat MARC1

    Additional mRNA sequence: 

    AK000035.1 AK026043.1 AK092439.1 AK094105.1 AK225416.1 AK290812.1 BC010619.1 

    4 DOTS entries:

    DT.115805  DT.100009724  DT.92420771  DT.97793152 

    Selected AceView cDNA sequences (see all 109):

    AI151008 AW673259 AW002743 N29359 BE646270 AA190676 AA483828 CR606830 
    AV682628 CD171974 BX339180 AI192767 BF589161 CF135110 AA926799 AA320944 
    AI168349 AA676308 R99392 AW467945 CA439234 BM794264 BX369326 BV197259 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for MARC1    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8
    SP1:                                -                 -                     
    SP2:                                                  -                     
    SP3:                                -                                       
    SP4:              -                                                         


    ECgene alternative splicing isoforms for MARC1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MARC1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGGACCCCT
    MARC1 Expression
    About this image


    MARC1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Neurons
             Mature Horizontal Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)
             Mature Horizontal Cells Inner Nuclear Layer
    MARC1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MARC1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.497816
        Custom PCR Arrays for MARC1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MARC1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for MARC1 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Marc11 , 5 MOCO sulphurase C-terminal domain containing 15
    mitochondrial amidoxime reducing component 11
    79.34(n)1
    79.04(a)1
      1 (89.07 cM)5
    661121  NM_001081361.11  NP_001074830.11 
     1847867765 
    chicken
    (Gallus gallus)
    Aves MARC21 mitochondrial amidoxime reducing component 2 67.59(n)
    63.08(a)
      428563  XM_426119.3  XP_426119.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 4)
    Uncharacterized protein
    (see all 4)
    6(a)
    56(a)
    (see all 4)
    many ↔ many
    many ↔ many
    (see all 4)
    GL344100.1(36229-61934)
    1(243573954-243586585)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.252532 Xenopus laevis transcribed sequence with weak similarity more 76.2(n)    BX845733.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1107831 zgc:110783 58.36(n)
    50.9(a)
      378742  NM_001014367.1  NP_001014389.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG16656
    --
    29(a)
    1 → many
    2R(5727283-5728667)
    worm
    (Caenorhabditis elegans)
    Secernentea F56A11.51 F56A11.5 48.63(n)
    37.99(a)
      176883  NM_067547.4  NP_499948.1 


    ENSEMBL Gene Tree for MARC1 (if available)
    TreeFam Gene Tree for MARC1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MARC1 gene
    MARC22  MOCOS2  
    1 SIMAP similar gene for MARC1 using alignment to 3 protein entries:     MOSC1_HUMAN (see all proteins):
    MARC2

    MARC1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MARC1 (see all 826)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs41245961,2
    C,F,A--220958149(-) AGCAGG/AATTGA 1 -- us2k16Minor allele frequency- A:0.04NS EA 310
    rs1895359961,2
    --220958220(+) CACTGA/CAATTT 1 -- us2k10--------
    rs1112950931,2
    F--220958312(+) AGGGCG/ATTGTG 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs3678243311,2
    C--220958401(+) TGGCT-/GGTTCC 1 -- us2k10--------
    rs39028851,2
    C,F--220958580(-) TAAGAG/TGAAAA 1 -- us2k1 trp313Minor allele frequency- T:0.04NS CSA WA EA 540
    rs673585771,2
    C,F--220958619(+) ATAAAC/TAGAAA 1 -- us2k111Minor allele frequency- T:0.04NS EA 416
    rs670658031,2
    C,F--220958645(+) CCGGAA/GCTGCC 1 -- us2k113Minor allele frequency- G:0.06NS CSA WA EA 536
    rs1845002191,2
    --220958717(+) CCTGGG/TGTTGG 1 -- us2k10--------
    rs673054551,2
    C,F--220958753(+) CAGGAC/GAGATA 1 -- us2k110Minor allele frequency- G:0.01NS 340
    rs1510620671,2
    --220958851(+) TCTCTC/TGGCGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for MARC1 (220960039 - 220987741 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for MARC1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MARC1
    DNA2.0 Custom Variant and Variant Library Synthesis for MARC1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614126    OMIM disorders: --

    1 disease for MARC1:    
    About MalaCards
    malaria


    MARC1 for disorders           About GeneDecksing


    Export disorders for MARC1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MARC1 gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with MARC1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The mitochondrial amidoxime-reducing component (mARC1) is a novel signal-anchored protein of the outer mitochondrial membrane. (PubMed id 23086957)1, 2 Klein J.M.... Schwarz G. (J. Biol. Chem. 2012)
    2. Reduction of N(omega)-hydroxy-L-arginine by the mitochondrial amidoxime reducing component (mARC). (PubMed id 21029045)1, 2 Kotthaus J.... Clement B. (Biochem. J. 2011)
    3. The fourth molybdenum containing enzyme mARC: cloning and involvement in the activation of N-hydroxylated prodrugs. (PubMed id 19053771)1, 2 Gruenewald S.... Clement B. (J. Med. Chem. 2008)
    4. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. MOSC domains: ancient, predicted sulfur-carrier domains, present in diverse metal-sulfur cluster biosynthesis proteins including Molybdenum cofactor sulfurases. (PubMed id 11886751)1, 3 Anantharaman V. and Aravind L. (FEMS Microbiol. Lett. 2002)
    8. The involvement of mitochondrial amidoxime reducing components 1 and 2 and mitochondrial cytochrome b5 in N-reductive metabolism in human cells. (PubMed id 23703616)1 Plitzko B....Havemeyer A. (J. Biol. Chem. 2013)
    9. Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. (PubMed id 23503661)1 Sarraf S.A....Harper J.W. (Nature 2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64757 HGNC: 26189 AceView: FLJ22390 Ensembl:ENSG00000186205 euGenes: HUgn64757
    ECgene: MARC1 H-InvDB: MARC1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MARC1 Pharmacogenomics, SNPs, Pathways
    NIEHS-SNPshttp://egp.gs.washington.edu/data/mosc1/

    (Patent information from GeneIP,
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    Patent Information for MARC1 gene:
    Search GeneIP for patents involving MARC1

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