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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MAPKBP1 Gene

protein-coding GIFtS: 49
GCID: GC15P042067

mitogen-activated protein kinase binding protein 1

(Previous name: mitogen activated protein kinase binding protein 1 )

Explore 2 diseases affiliated with
MAPKBP1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Mitogen-Activated Protein Kinase Binding Protein 1¹ ²		JNK-Binding Protein 1² ³
Mitogen Activated Protein Kinase Binding Protein 1¹ ²		Mitogen-Activated Protein Kinase-Binding Protein 1²
KIAA0596¹ ³		JNKBP1³
JNKBP-1² ³

External Ids:	HGNC: 29536¹	Entrez Gene: 23005²	Ensembl: ENSG00000137802⁷	UniProtKB: O60336³

Export aliases for MAPKBP1 gene to outside databases

Previous GC identifers: GC15P037434 GC15P034962 GC15P039645 GC15P039782 GC15P039855 GC15P018915

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MABP1_HUMAN, O60336

Function: Involved in JNK signaling pathway (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000015.9 NC_018926.1 NT_010194.17

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the MAPKBP1 gene promoter:
Nkx3-1 HFH-3 Brachyury SREBP-1c SREBP-1b Evi-1 AREB6 FOXI1 SREBP-1a
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MAPKBP1 promoter sequence

Search SABiosciences Chromatin IP Primers for MAPKBP1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAPKBP1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q15.1 Ensembl cytogenetic band: 15q15.1 HGNC cytogenetic band: 15q15.1

MAPKBP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAPKBP1 gene location

GeneLoc information about chromosome 15 GeneLoc Exon Structure

GeneLoc location for GC15P042067: view genomic region (about GC identifiers)

Start:	42,066,632 bp from pter	End:	42,120,053 bp from pter
Size:	53,422 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MABP1_HUMAN, O60336 (See protein sequence)

Recommended Name: Mitogen-activated protein kinase-binding protein 1

Size: 1514 amino acids; 163818 Da

Subunit: Interacts with MAPK10 (By similarity)

Sequence caution: Sequence=BAA25522.2; Type=Erroneous initiation;

Secondary accessions: A6NM93 A8K8P9 Q14CB5 Q14CD8 Q49AJ8 Q5W9G9

Alternative splicing: 6 isoforms: O60336-1 O60336-2 O60336-3 O60336-4 O60336-5 O60336-6 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MAPKBP1: NX_O60336

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O60336

MAPKBP1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001122080.1 NP_001252540.1 NP_055809.2

ENSEMBL proteins:

ENSP00000427582 ENSP00000397570 ENSP00000421891 ENSP00000393099 ENSP00000426154

ENSP00000422132 ENSP00000221214 ENSP00000260357

Human Recombinant Protein Products:

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	Uscn Proteins for MAPKBP1

MAPKBP1 Antibody Products:

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	Novus Biologicals MAPKBP1 Antibodies
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	Uscn Antibodies for MAPKBP1
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Assay Products for MAPKBP1:

	Browse Kits and Assays available from EMD Millipore
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	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for MAPKBP1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for MAPKBP1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

MAPKBP1 for domains About GeneDecksing

3 InterPro domains/families:

IPR001680 WD40_repeat

IPR017986 WD40_repeat_dom

IPR015943 WD40/YVTN_repeat-like_dom

Graphical View of Domain Structure for InterPro Entry O60336

ProtoNet protein and cluster: O60336

UniProtKB/Swiss-Prot: MABP1_HUMAN, O60336

Similarity: Contains 12 WD repeats

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: MABP1_HUMAN, O60336

Function: Involved in JNK signaling pathway (By similarity)

miRNA Products:		OriGene 3'-UTR Clone (see all 2): MAPKBP1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MAPKBP1
		8/53 QIAGEN miScript miRNA Assays for microRNAs that regulate MAPKBP1 (see all 53):
		hsa-miR-607 hsa-miR-3194-5p hsa-miR-485-3p hsa-miR-29a hsa-miR-3138 hsa-miR-486-3p hsa-miR-650 hsa-miR-105

		SwitchGear 3'UTR luciferase reporter plasmid: MAPKBP1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MAPKBP1 (see all 7) OriGene shRNA RFP: MAPKBP1 OriGene siRNA: MAPKBP1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAPKBP1

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for MAPKBP1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAPKBP1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAPKBP1 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): MAPKBP1 (NM_014994)
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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAPKBP1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for MAPKBP1
		Search LifeMap BioReagents cell lines for MAPKBP1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAPKBP1

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	--	--

MAPKBP1 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for MAPKBP1:

Decreased viability of wild-ty

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MAPKBP1

5/7 Interacting proteins for MAPKBP1 (O60336^{2, 3}) via UniProtKB, MINT, STRING, and/or I2D (see all 7)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
APTX	Q7Z2E3²^,³	MINT-2870118 I2D: score=3
MAPK10	P53779³	I2D: score=3
MAPK9	P45984³	I2D: score=3
MAPK8	P45983³	I2D: score=2
MAP3K7	O43318³	I2D: score=1

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007256	activation of JNKK activity	IEA	--

MAPKBP1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MAPKBP1
Search CenterWatch for drugs/clinical trials and news about MAPKBP1 / MABP1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MAPKBP1 gene (3 alternative transcripts):

NM_001128608.1 NM_001265611.1 NM_014994.2

Unigene Cluster for MAPKBP1:

Mitogen-activated protein kinase binding protein 1

Hs.513661 [show with all ESTs]

Unigene Representative Sequence: NM_001128608

18 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000512970 ENST00000457542(uc001zok.4 uc001zoj.4 uc010bcj.3 uc010bci.3 uc010udb.2 uc010bck.3 uc010bcl.3)

ENST00000505373 ENST00000456763 ENST00000514566 ENST00000502292 ENST00000510535

ENST00000505061 ENST00000507762 ENST00000515164 ENST00000507147 ENST00000503526

ENST00000508050 ENST00000506301 ENST00000502695 ENST00000512433 ENST00000221214

ENST00000260357

miRNA Products:		OriGene 3'-UTR Clone (see all 2): MAPKBP1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MAPKBP1
		8/53 QIAGEN miScript miRNA Assays for microRNAs that regulate MAPKBP1 (see all 53):
		hsa-miR-607 hsa-miR-3194-5p hsa-miR-485-3p hsa-miR-29a hsa-miR-3138 hsa-miR-486-3p hsa-miR-650 hsa-miR-105

		SwitchGear 3'UTR luciferase reporter plasmid: MAPKBP1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MAPKBP1 (see all 7) OriGene shRNA RFP: MAPKBP1 OriGene siRNA: MAPKBP1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAPKBP1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAPKBP1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAPKBP1 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): MAPKBP1 (NM_014994)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MAPKBP1
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Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAPKBP1 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAPKBP1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAPKBP1

Additional cDNA sequence:

AB011168.2 AB177850.1 AK091616.1 AK292414.1 AK302482.1 AL833267.1 AL834413.1 BC111090.1

BC113983.1 BC114493.1 BX648786.1 NR_049761.1 NR_049762.1

19 DOTS entries:

DT.100814991 DT.409769 DT.97836514 DT.95366070 DT.97767632 DT.411781 DT.100711128 DT.100036105

DT.102823467 DT.75117545 DT.91663210 DT.100814990 DT.95366069 DT.121073181 DT.70100075 DT.91714025

DT.97783563 DT.100036106 DT.91653804

24/91 AceView cDNA sequences (see all 91):

BQ959299 CK904274 BM476443 CR609233 AI368862 AL046558 CA312846 AL079848

BQ045172 AL043360 CO245500 BX489812 AI350720 BG744410 BG675754 BC036660

BX354967 BX415355 D80617 BM018726 AU140717 BM457135 BM978422 BM559468

GeneLoc Exon Structure

5/13 Alternative Splicing Database (ASD) splice patterns (SP) for MAPKBP1 (see all 13) About this scheme

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12a	·	12b	^	13a	·	13b	^	14	^	15	^	16a	·	16b	^	17a	·	17b	^	18a	·	18b	·	18c	^	19	^	20a	·
SP1:
SP2:																																											-				-		-
SP3:
SP4:
SP5:

ExUns:	20b	^	21a	·	21b	^	22a	·	22b	·	22c	·	22d	^	23a	·	23b	^	24a	·	24b	^	25a	·	25b	^	26	^	27	^	28	^	29
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for MAPKBP1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MAPKBP1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGGCGGGGGC

About this image

MAPKBP1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

PureStem™ progenitor Z1 (Embryonic Progenitor Cell)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See MAPKBP1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MAPKBP1

SOURCE GeneReport for Unigene cluster: Hs.513661

SABiosciences Custom PCR Arrays for MAPKBP1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAPKBP1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat MAPKBP1
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAPKBP1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAPKBP1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for MAPKBP1 gene from 6/22 species (see all 22) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	MAPKBP1¹	mitogen activated protein kinase binding protein 1	66.06(n) 67.63(a)		771487 XM_003641348.1 XP_003641396.1
lizard (Anolis carolinensis)	Reptilia	MAPKBP1⁶	--	65(a)	1 ↔ 1	1(40873601-40927600)
zebrafish (Danio rerio)	Actinopterygii	LOC100535386¹	mitogen-activated protein kinase-binding protein 1-like	66.63(n) 66.7(a)		100535386 XM_003200317.1 XP_003200365.1
fruit fly (Drosophila melanogaster)	Insecta	CG7337⁶	--	19(a)	1 → many	2L(1884622-1944289)
worm (Caenorhabditis elegans)	Secernentea	H24G06.1⁶	Protein H24G06.1, isoform d	11(a)	1 → many	V(9446149-9460615)
thale cress (Arabidopsis thaliana)	eudicotyledons	AT3G09080⁶	transducin/WD40 domain-containing protein	20(a)	1 → many	3(2776259-2781785)

ENSEMBL Gene Tree for MAPKBP1 (if available)
TreeFam Gene Tree for MAPKBP1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for MAPKBP1 gene

EML3² EML5² WDR16² EML1² EML2² WDR62² EML4² EML6²

WDR90²

1 SIMAP similar gene for MAPKBP1 using alignment to 7 protein entries: MABP1_HUMAN (see all proteins):

WDR62

MAPKBP1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 15 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs187047384^1,2		--	42064694(+)	`GTGGCA/GCGTGC`	5	--	us2k¹		0	--	--	--	--
rs144440532^1,2		--	42064708(+)	`TAATCC/TCAGCT`	5	--	us2k¹		0	--	--	--	--
rs189843467^1,2		--	42064781(+)	`GATCGC/TCACTG`	5	--	us2k¹		0	--	--	--	--
rs68025753^1,2	C	--	42064821(+)	`AAAAA-/AAA AAAAAAAAAAA`	5	--	us2k¹		1		NA	2
rs56942810^1,2	F,	--	42065017(+)	`ATGATC/TTGGAG`	5	--	us2k¹		1		WA	118
rs145964637^1,2		--	42065035(+)	`GGGACA/GGCTCT`	5	--	us2k¹		0	--	--	--	--
rs139880538^1,2		--	42065215(+)	`GTAGCC/TAATGG`	5	--	us2k¹		0	--	--	--	--
rs116487777^1,2		--	42065220(+)	`TAATGG/CTTCTT`	5	--	us2k¹		1		WA	118
rs182520286^1,2		--	42065230(+)	`TGCCTC/TCTTCT`	5	--	us2k¹		0	--	--	--	--
rs186165175^1,2		--	42065231(+)	`GCCTTC/TTTCTT`	5	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for MAPKBP1 (42066632 - 42120053 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for MAPKBP1
2 CNVs: 3078 30707
1 Indel: 33284

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAPKBP1

DNA2.0 Custom Variant and Variant Library Synthesis for MAPKBP1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

MAPKBP1 for disorders About GeneDecksing

2 diseases for MAPKBP1: About MalaCards

ataxia malaria

Human Genome Epidemiology (HuGE) Navigator: MAPKBP1 (4 documents)

Export disorders for MAPKBP1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MAPKBP1 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with MAPKBP1)

Utopia: connect your pdf to the dynamic
world of online information

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)^{1, 2, 3} Nagase T....Ohara O. (1998)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Alternative splice variants encoding unstable protein domains exist in the human brain. (PubMed id 15491607)^{1, 2} Homma K.... Nishikawa K. (2004)
A novel Jun N-terminal kinase (JNK)-binding protein that enhances the activation of JNK by MEK kinase 1 and TGF-beta-activated kinase 1. (PubMed id 10471813)^{1, 3} Koyano S....Yoshioka K. (1999)
The c-Jun N-terminal kinase (JNK)-binding protein (JNK BP1) acts as a negative regulator of NOD2 protein signaling by inhibiting its ol igomerization process. (PubMed id 22700971)¹ Lecat A....Legrand-Poels S. (2012)
Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)² Zody M.C....Nusbaum C. (2006)
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)¹ Lim J.... Zoghbi H.Y. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 23005	HGNC: 29536	AceView: MAPKBP1	Ensembl:ENSG00000137802	euGenes: HUgn23005
ECgene: MAPKBP1	H-InvDB: MAPKBP1

(According to HUGE)
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HUGE: KIAA0596

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for MAPKBP1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for MAPKBP1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for MAPKBP1 gene:
Search GeneIP for patents involving MAPKBP1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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MAPKBP1 Gene

mitogen-activated protein kinase binding protein 1

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MAPKBP1 Gene

mitogen-activated protein kinase binding protein 1

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