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Aliases for MAP7D2 Gene

Aliases for MAP7D2 Gene

  • MAP7 Domain Containing 2 2 3

External Ids for MAP7D2 Gene

Previous GeneCards Identifiers for MAP7D2 Gene

  • GC0XM019935
  • GC0XM017770

Summaries for MAP7D2 Gene

GeneCards Summary for MAP7D2 Gene

MAP7D2 (MAP7 Domain Containing 2) is a Protein Coding gene. An important paralog of this gene is MAP7D1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAP7D2 Gene

Genomics for MAP7D2 Gene

Regulatory Elements for MAP7D2 Gene

Genomic Location for MAP7D2 Gene

Start:
20,006,713 bp from pter
End:
20,116,996 bp from pter
Size:
110,284 bases
Orientation:
Minus strand

Genomic View for MAP7D2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MAP7D2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAP7D2 Gene

Proteins for MAP7D2 Gene

  • Protein details for MAP7D2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96T17-MA7D2_HUMAN
    Recommended name:
    MAP7 domain-containing protein 2
    Protein Accession:
    Q96T17
    Secondary Accessions:
    • B7Z2J8
    • B7Z3S7
    • B9EGC7
    • C9JMA4
    • C9JYW0
    • Q5EBN1
    • Q5JPS7
    • Q6PIC7
    • Q8N792

    Protein attributes for MAP7D2 Gene

    Size:
    732 amino acids
    Molecular mass:
    81965 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC05407.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for MAP7D2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MAP7D2 Gene

Proteomics data for MAP7D2 Gene at MOPED

Post-translational modifications for MAP7D2 Gene

  • Ubiquitination at Lys217
  • Modification sites at PhosphoSitePlus

Other Protein References for MAP7D2 Gene

No data available for DME Specific Peptides for MAP7D2 Gene

Domains for MAP7D2 Gene

Protein Domains for MAP7D2 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q96T17

UniProtKB/Swiss-Prot:

MA7D2_HUMAN :
  • Q96T17
Family:
  • Belongs to the MAP7 family.
genes like me logo Genes that share domains with MAP7D2: view

No data available for Gene Families for MAP7D2 Gene

Function for MAP7D2 Gene

Gene Ontology (GO) - Molecular Function for MAP7D2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005198 structural molecule activity IBA --
genes like me logo Genes that share ontologies with MAP7D2: view

Phenotypes for MAP7D2 Gene

MGI mutant phenotypes for MAP7D2:
inferred from 1 alleles
genes like me logo Genes that share phenotypes with MAP7D2: view

Animal Model Products

CRISPR Products

miRNA for MAP7D2 Gene

miRTarBase miRNAs that target MAP7D2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for MAP7D2 Gene

Localization for MAP7D2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MAP7D2 Gene COMPARTMENTS Subcellular localization image for MAP7D2 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for MAP7D2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IBA --
GO:0005874 microtubule IEA --
GO:0015630 microtubule cytoskeleton IBA --
genes like me logo Genes that share ontologies with MAP7D2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for MAP7D2 Gene

Pathways for MAP7D2 Gene

SuperPathways for MAP7D2 Gene

No Data Available

Interacting Proteins for MAP7D2 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000368964%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000334499%0d%0a
Selected Interacting proteins: ENSP00000368964 Q96T17-MA7D2_HUMAN for MAP7D2 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for MAP7D2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000226 microtubule cytoskeleton organization IBA --
genes like me logo Genes that share ontologies with MAP7D2: view

No data available for Pathways by source for MAP7D2 Gene

Transcripts for MAP7D2 Gene

Unigene Clusters for MAP7D2 Gene

MAP7 domain containing 2:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MAP7D2

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for MAP7D2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MAP7D2 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c · 7d ^ 8a · 8b ^ 9a · 9b · 9c · 9d ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13a ·
SP1: - - - - - - -
SP2: - - - - - - -
SP3: - - - - -
SP4: - - - -
SP5:
SP6: - - - - - - - -
SP7: - - - - - - - - - - - - - - - - -
SP8: - - - -
SP9:
SP10: - - -
SP11: - - - -
SP12: -
SP13: - - - - - - -
SP14:
SP15: - - -

ExUns: 13b · 13c ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^ 21
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:

Relevant External Links for MAP7D2 Gene

GeneLoc Exon Structure for
MAP7D2
ECgene alternative splicing isoforms for
MAP7D2

Expression for MAP7D2 Gene

mRNA expression in normal human tissues for MAP7D2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MAP7D2 Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (6.1), Brain - Anterior cingulate cortex (BA24) (5.5), and Brain - Cortex (4.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for MAP7D2 Gene

SOURCE GeneReport for Unigene cluster for MAP7D2 Gene Hs.127951

genes like me logo Genes that share expressions with MAP7D2: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for MAP7D2 Gene

Orthologs for MAP7D2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MAP7D2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MAP7D2 35
  • 99.13 (n)
  • 98.96 (a)
MAP7D2 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MAP7D2 36
  • 73 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MAP7D2 35
  • 86.32 (n)
  • 82.77 (a)
MAP7D2 36
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Map7d2 35
  • 79.43 (n)
  • 75.29 (a)
Map7d2 16
Map7d2 36
  • 70 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MAP7D2 36
  • 62 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MAP7D2 36
  • 57 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Map7d2 35
  • 79.43 (n)
  • 74.81 (a)
chicken
(Gallus gallus)
Aves MAP7D2 35
  • 69.57 (n)
  • 64.56 (a)
MAP7D2 36
  • 60 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MAP7D2 36
  • 60 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia map7d2 35
  • 63.51 (n)
  • 57.04 (a)
Str.7455 35
zebrafish
(Danio rerio)
Actinopterygii map7d2a 36
  • 31 (a)
OneToMany
map7d2b 36
  • 31 (a)
OneToMany
Species with no ortholog for MAP7D2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MAP7D2 Gene

ENSEMBL:
Gene Tree for MAP7D2 (if available)
TreeFam:
Gene Tree for MAP7D2 (if available)

Paralogs for MAP7D2 Gene

Paralogs for MAP7D2 Gene

genes like me logo Genes that share paralogs with MAP7D2: view

Variants for MAP7D2 Gene

Sequence variations from dbSNP and Humsavar for MAP7D2 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs4077051 -- 20,020,808(+) GCCTG(C/G)CTACG intron-variant
rs4297225 -- 20,042,242(+) TGGAC(C/G)TAAAG intron-variant
rs4370706 -- 20,084,788(+) GGTCT(C/T)GAACT intron-variant
rs4400548 -- 20,027,318(+) GCTTA(A/G)CAATC intron-variant
rs4403568 -- 20,028,197(+) gctta(A/G)agagg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MAP7D2 Gene

Variant ID Type Subtype PubMed ID
nsv6827 CNV Loss 18451855
nsv425374 CNV Loss 16902084

Relevant External Links for MAP7D2 Gene

HapMap Linkage Disequilibrium report
MAP7D2
Locus Specific Mutation Databases (LSDB)
MAP7D2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MAP7D2 Gene

Disorders for MAP7D2 Gene

No disorders were found for MAP7D2 Gene.

No data available for UniProtKB/Swiss-Prot for MAP7D2 Gene

Publications for MAP7D2 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  4. The consensus coding sequences of human breast and colorectal cancers. (PMID: 16959974) Sjoeblom T. … Velculescu V.E. (Science 2006) 3 4
  5. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PMID: 19413330) Gauci S. … Mohammed S. (Anal. Chem. 2009) 3 4

Products for MAP7D2 Gene

Sources for MAP7D2 Gene

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