MAP7D2 Gene
protein-coding GIFtS: 41
GCID: GC0XM020024
|
|
MAP7 domain containing 2
| |
Aliases
for MAP7D2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| MAP7 Domain Containing 21 2 | | FLJ145031 | | MAP7 Domain Containing 2 Protein Varaint 12 | | MAP7 Domain Containing 2 Protein Varaint 22 | | MAP7 Domain-Containing Protein 22 |
Export aliases for MAP7D2 gene to outside databasesPrevious GC identifers: GC0XM019935 GC0XM017770 |
Summaries
for MAP7D2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for MAP7D2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_167197.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MAP7D2 gene promoter:
AhR MEF-2 CUTL1 Arnt MEF-2A SRY FOXO1a FOXJ2 aMEF-2 FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MAP7D2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAP7D2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp22.12 Ensembl cytogenetic band: Xp22.12 HGNC cytogenetic band: Xp22.12MAP7D2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM020024: view genomic region
(about GC identifiers)
Start:
|
20,024,831 bp from pter |
End:
|
20,135,114 bp from pter |
Size:
|
110,284 bases |
Orientation:
|
minus strand |
|
Proteins
for MAP7D2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MA7D2_HUMAN, Q96T17 (See
protein sequence)Recommended Name: MAP7 domain-containing protein 2 Size: 732 amino acids; 81965 Da
Sequence caution: Sequence=BAC05407.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B7Z2J8 B7Z3S7 B9EGC7 C9JMA4 C9JYW0 Q5EBN1 Q5JPS7 Q6PIC7 Q8N792Alternative splicing: 5 isoforms: Q96T17-1 Q96T17-2 Q96T17-3 Q96T17-4 Q96T17-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MAP7D2: NX_Q96T17
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96T17
MAP7D2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001161937.1 NP_001161938.1 NP_001161939.1 NP_689993.2
ENSEMBL proteins: ENSP00000368972 ENSP00000368964 ENSP00000450876 ENSP00000388239 ENSP00000413301 ENSP00000440691
Human Recombinant Protein Products:
MAP7D2 Antibody Products:
Assay Products for MAP7D2: |
Protein
Domains /
Families
for MAP7D2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MAP7D2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96T17ProtoNet protein and cluster: Q96T17 UniProtKB/Swiss-Prot: MA7D2_HUMAN, Q96T17Similarity: Belongs to the MAP7 family |
Function
for MAP7D2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAP7D2 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAP7D2 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): MAP7D2 (NM_152780) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MAP7D2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAP7D2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAP7D2 |
Animal Models:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Map7d2):
MAP7D2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for MAP7D2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MAP7D2
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
2 Interacting proteins for MAP7D2 (Q96T173 ENSP000003689724) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for MAP7D2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MAP7D2
Search CenterWatch for drugs/clinical trials and news about MAP7D2 / MA7D2
|
Transcripts
for MAP7D2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MAP7D2 gene (4 alternative transcripts): NM_001168465.1 NM_001168466.1 NM_001168467.1 NM_152780.3 Unigene Cluster for MAP7D2: MAP7 domain containing 2 Hs.127951 [show with all ESTs]Unigene Representative Sequence: NM_0011684657 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000379651(uc004czq.2 uc011mji.2 uc010nfo.2 uc004czr.2 uc011mjj.2)
ENST00000379643 ENST00000485173(uc004czs.1) ENST00000443379 ENST00000452324
ENST00000466145 ENST00000543767
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAP7D2 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAP7D2 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): MAP7D2 (NM_152780) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MAP7D2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAP7D2 |
Additional cDNA sequence: AK027409.1 AK098768.1 AK127056.1 AK294788.1 AK296319.1 AK303019.1 AK316117.1 BC037165.2 BC052256.1 BC089400.1 BC136379.1 8 DOTS entries: DT.100026071 DT.454071 DT.121299349 DT.121299379 DT.91674636 DT.100315 DT.121299351 DT.121299354 24/93 AceView cDNA sequences (see all 93): BF057813 BC052256 CB306139 AI273383 AW470871 BP362745 BP362465 AI277048 BP369690 R45145 AK127056 AI091319 AA988024 AW237462 AW205321 AI934583 AK027409 Z41048 NM_152780 BC037165 Z45335 AA336956 AA969410 BQ652601
GeneLoc Exon Structure
5/15 Alternative Splicing Database (ASD) splice patterns (SP) for MAP7D2 (see all 15) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | · | 9d | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · |
|---|
|
| SP1: | | | | | | | - | | - | | - | | | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | - | | | | - | | | | | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | | | - | | | | | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 13b | · | 13c | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | ^ | 21 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MAP7D2
|
Expression
for MAP7D2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MAP7D2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATATGTACCT
About this image
See MAP7D2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MAP7D2
SOURCE GeneReport for Unigene cluster: Hs.127951
SABiosciences Custom PCR Arrays for MAP7D2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAP7D2
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAP7D2 |
Orthologs
for MAP7D2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for MAP7D2 gene from 5/16 species (see all 16) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
MAP7D21 |
MAP7 domain containing 2 |
71.52(n)
67.14(a) |
|
418607 XM_003640488.1 XP_003640536.1 |
lizard
(Anolis carolinensis) |
Reptilia |
MAP7D26 |
-- |
60(a) |
1 ↔ 1 |
3(123825371-123861989) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.74552 |
Transcribed sequence with weak similarity to protein more |
78.23(n) |
|
142022249 |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC1000051951 |
novel protein similar to mouse microtubule-associated more |
49.46(n)
41.12(a) |
|
100005195 NM_001100092.2 NP_001093562.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
ens6 |
ensconsin |
10(a) |
1 → many |
3L(4123138-4134550) |
ENSEMBL Gene Tree for MAP7D2 (if available)
TreeFam Gene Tree for MAP7D2 (if available) |
Paralogs
for MAP7D2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MAP7D2 gene
- INCENP2 MAP7D32 MAP7D12 MAP72
1 SIMAP similar gene for MAP7D2 using alignment to 5 protein entries: MA7D2_HUMAN (see all proteins):MAP7
MAP7D2 for paralogs About GeneDecksing
|
Genomic Variants
for MAP7D2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MAP7D2 (20024831 - 20135114 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MAP7D2: --
Locus Specific Mutation Databases (LSDB): MAP7D2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAP7D2 |
|
Disorders
/ Diseases
for MAP7D2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for MAP7D2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MAP7D2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with MAP7D2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)1, 2 Sjoeblom T.... Velculescu V.E. (2006)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)1 Gauci S....Mohammed S. (2009)
- Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
|
External Searches for MAP7D2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MAP7D2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MAP7D2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MAP7D2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MAP7D2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MAP7D2 gene:
Search GeneIP for patents involving MAP7D2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MAP7D2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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| |
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| |
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| |  |  |  |  | | | | |
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 |
 |
 | | | MAP7D2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAP7D2 |
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