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MAP7D1 Gene

protein-coding   GIFtS: 51
GCID: GC01P036621

MAP7 Domain Containing 1

(Previous names: proline arginine rich coiled coil 1, arginine/proline rich...)
(Previous symbols: PARCC1, RPRC1)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
MAP7 Domain Containing 11 2     Arginine/Proline-Rich Coiled-Coil Domain-Containing Protein 12 3
PARCC11 2 3     Proline/Arginine-Rich Coiled-Coil Domain-Containing Protein 12 3
RPRC11 2 3     MAP7 Domain-Containing Protein 12
Arginine/Proline Rich Coiled-Coil 11 2     KIAA11873
Proline Arginine Rich Coiled Coil 11 2     

External Ids:    HGNC: 255141   Entrez Gene: 557002   Ensembl: ENSG000001168717   UniProtKB: Q3KQU33   

Export aliases for MAP7D1 gene to outside databases

Previous GC identifers: GC01P036395 GC01P034738


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MAP7D1 Gene:
MAP7D1 (MAP7 domain containing 1) is a protein-coding gene. An important paralog of this gene is MAP7D2.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MAP7D1 gene promoter:
         MyoD   Lmo2   MEF-2A   S8   GATA-6   Nkx6-1   c-Myb   ARP-1   aMEF-2   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMAP7D1 promoter sequence
   Search Chromatin IP Primers for MAP7D1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MAP7D1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.3   Ensembl cytogenetic band:  1p34.3   HGNC cytogenetic band: 1p34.3

MAP7D1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAP7D1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P036621:  view genomic region     (about GC identifiers)

Start:
36,621,180 bp from pter      End:
36,646,450 bp from pter
Size:
25,271 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: MA7D1_HUMAN, Q3KQU3 (See protein sequence)
Recommended Name: MAP7 domain-containing protein 1  
Size: 841 amino acids; 92820 Da
Sequence caution: Sequence=AAG17244.1; Type=Frameshift; Positions=80, 207, 736; Sequence=BAA86501.2;
Type=Erroneous initiation;
Secondary accessions: D3DPS4 Q7L8J5 Q8N905 Q8TAK0 Q9HBQ2 Q9NW29 Q9ULN3
Alternative splicing: 4 isoforms:  Q3KQU3-1   Q3KQU3-2   Q3KQU3-3   Q3KQU3-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MAP7D1: NX_Q3KQU3

Explore proteomics data for MAP7D1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys268, Lys272, Lys439
  • Modification sites at PhosphoSitePlus

  • See MAP7D1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001273294.1  NP_001273295.1  NP_060537.3  

    ENSEMBL proteins: 
     ENSP00000390091   ENSP00000320228   ENSP00000362243   ENSP00000362244   ENSP00000435126  
     ENSP00000437046   ENSP00000362241  

    MAP7D1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for MAP7D1

     
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    antibodies-online peptides for MAP7D1

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    antibodies-online kits for MAP7D1 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR008604 MAP7

    Graphical View of Domain Structure for InterPro Entry Q3KQU3

    ProtoNet protein and cluster: Q3KQU3

    UniProtKB/Swiss-Prot: MA7D1_HUMAN, Q3KQU3
    Similarity: Belongs to the MAP7 family


    Find genes that share domains with MAP7D1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         1 GenomeRNAi human phenotype for MAP7D1:
     Increased circadian rhythm amp 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for MAP7D1

    miRNA
    Products:
        
    miRTarBase miRNAs that target MAP7D1:
    hsa-mir-100-5p (MIRT048388), hsa-mir-320b (MIRT036182), hsa-mir-615-3p (MIRT040351), hsa-mir-186-5p (MIRT045138), hsa-mir-18a-3p (MIRT040902), hsa-mir-484 (MIRT042300), hsa-let-7b-5p (MIRT005227), hsa-mir-18a-5p (MIRT031359)

    Block miRNA regulation of human, mouse, rat MAP7D1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MAP7D1 (see all 15):
    hsa-miR-18a hsa-miR-516b hsa-miR-130a* hsa-miR-200a hsa-miR-16-1* hsa-miR-23c hsa-miR-141 hsa-miR-935
    SwitchGear 3'UTR luciferase reporter plasmidMAP7D1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for MAP7D1
    Predesigned siRNA for gene silencing in human, mouse, rat MAP7D1

    Gene Editing
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAP7D1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MA7D1_HUMAN, Q3KQU3: Cytoplasm, cytoskeleton, spindle
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    nucleus3
    cytosol1
    mitochondrion1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005819spindle IEA--
    GO:0005874microtubule IEA--
    GO:0015630microtubule cytoskeleton IDA--

    Find genes that share ontologies with MAP7D1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MAP7D1
    Interactions:

        Search GeneGlobe Interaction Network for MAP7D1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    Selected Interacting proteins for MAP7D1 (Q3KQU32, 3 ENSP000003622444) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATN1P542592, 3, ENSP000003490764MINT-2874537 I2D: score=3 STRING: ENSP00000349076
    MYCP011063, ENSP000003672074I2D: score=2 STRING: ENSP00000367207
    USP20Q9Y2K63, ENSP000003138114I2D: score=2 STRING: ENSP00000313811
    MAP1LC3AQ9H4923, ENSP000003639704I2D: score=1 STRING: ENSP00000363970
    APOA1P026473I2D: score=4 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000226microtubule cytoskeleton organization IEA--

    Find genes that share ontologies with MAP7D1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MAP7D1 (MA7D1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MAP7D1 gene (3 alternative transcripts): 
    NM_001286365.1  NM_001286366.1  NM_018067.4  

    Unigene Cluster for MAP7D1:

    MAP7 domain containing 1
    Hs.356096  [show with all ESTs]
    Unigene Representative Sequence: AB033013
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000429533 ENST00000316156(uc001cab.3) ENST00000527764 ENST00000373150(uc001caa.3)
    ENST00000373151(uc001bzz.3 uc001cac.3) ENST00000530729 ENST00000462118
    ENST00000474796 ENST00000530975 ENST00000487131 ENST00000373148(uc001cad.3)
    ENST00000532131 ENST00000487114
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MAP7D1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MAP7D1 (see all 15):
    hsa-miR-18a hsa-miR-516b hsa-miR-130a* hsa-miR-200a hsa-miR-16-1* hsa-miR-23c hsa-miR-141 hsa-miR-935
    SwitchGear 3'UTR luciferase reporter plasmidMAP7D1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MAP7D1
    Predesigned siRNA for gene silencing in human, mouse, rat MAP7D1
    Clone
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    OriGene clones in human, mouse for MAP7D1 (see all 8)
    OriGene ORF clones in mouse, rat for MAP7D1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MAP7D1 (NM_018067)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MAP7D1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAP7D1
    Primer
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    OriGene qPCR primer pairs and template standards for MAP7D1
    OriGene qSTAR qPCR primer pairs in human, mouse for MAP7D1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MAP7D1
      QuantiTect SYBR Green Assays in human, mouse, rat MAP7D1
      QuantiFast Probe-based Assays in human, mouse, rat MAP7D1

    Additional mRNA sequence: 

    AB033013.2 AF064852.1 AF218002.1 AK001212.1 AK095939.1 AK096341.1 AK309966.1 AL136547.1 
    AY007099.1 BC003083.2 BC015885.1 BC027334.1 BC057293.1 BC067256.1 BC082266.1 BC106053.1 
    BC111428.1 BC128042.1 CR457254.1 

    23 DOTS entries:

    DT.100713109  DT.100061020  DT.100887622  DT.95099920  DT.91702504  DT.100745174  DT.100745173  DT.95295863 
    DT.100819652  DT.121363546  DT.95085208  DT.95196559  DT.97855104  DT.100044918  DT.95196558  DT.100061019 
    DT.121363726  DT.95196563  DT.95196582  DT.97784741  DT.100747337  DT.121363671  DT.95223214 

    Selected AceView cDNA sequences (see all 378):

    BQ005849 BC027334 CA423124 BM825042 AW163601 BU178034 AB033013 AI282678 
    BM550323 BQ008870 BQ000951 BQ674778 AI089272 BM848737 CD365136 BM844594 
    CD367202 BM818822 BM849326 BU687144 BC003083 BQ431494 BM672308 AI373393 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MAP7D1 (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16a · 16b
    SP1:                                                                                                              -                                       
    SP2:                                                                                                              -                                       
    SP3:                                                                                                                                                      
    SP4:                                      -     -                                                                                                         
    SP5:                                      -     -                                                                                                         


    ECgene alternative splicing isoforms for MAP7D1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MAP7D1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCCCTGCCC
    MAP7D1 Expression
    About this image


    MAP7D1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 9) fully expand
     
     Gonad (Reproductive System)
             Primordial Germ Cells Primitive Gonad
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Uterus (Reproductive System)
     
     Lung (Respiratory System)
    MAP7D1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MAP7D1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.356096
        Custom PCR Arrays for MAP7D1
    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat MAP7D1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAP7D1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for MAP7D1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Map7d11 , 5 microtubule-associated protein 7 domain containing more5
    MAP7 domain containing 11
    87.07(n)1
    87.11(a)1
      4 (60.16 cM)5
    2458771  NM_144941.31  NP_659190.31 
     1262321675 
    chicken
    (Gallus gallus)
    Aves MAP7D11 MAP7 domain containing 1 66.9(n)
    62.12(a)
      419624  XM_417771.4  XP_417771.4 
    lizard
    (Anolis carolinensis)
    Reptilia MAP7D16
    MAP7 domain containing 1
    50(a)
    1 ↔ 1
    GL343558.1(204060-272081)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.156652 Xenopus laevis transcribed sequence with weak similarity more 77.43(n)    BX850956.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.62042 Transcribed sequence with weak similarity to protein more 76(n)    57052547 


    ENSEMBL Gene Tree for MAP7D1 (if available)
    TreeFam Gene Tree for MAP7D1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MAP7D1 gene
    MAP7D22  MAP7D32  MAP72  
    2 SIMAP similar genes for MAP7D1 using alignment to 6 protein entries:     MA7D1_HUMAN (see all proteins):
    RPRC1    MAP7

    Find genes that share paralogs with MAP7D1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MAP7D1 (see all 537)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs768396601,2
    C--36623744(+) GGGCA-/GGGGGG 1 -- int10--------
    rs1150455351,2
    C,F--36623762(+) GTGGGC/TGGGGA 1 -- int11Minor allele frequency- T:0.03WA 118
    rs775668601,2
    F--36623787(+) GCCGGT/AGGGCA 1 -- int12Minor allele frequency- A:0.03CSA WA 120
    rs1845462771,2
    --36623996(+) CACTCC/TGAGAG 1 -- int10--------
    rs1443865681,2
    --36624004(+) GAGCAC/TGTGAC 1 -- int10--------
    rs1142221321,2
    F--36624095(+) TGTGGG/AGACCA 1 -- int11Minor allele frequency- A:0.02WA 118
    rs1126062771,2
    C,F--36624178(+) TACCTC/TCTGGA 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs1895165961,2
    --36624218(+) GCAGTA/GTTGTC 1 -- int10--------
    rs2728321,2
    C,F,A,H--36624234(-) TTAACC/GCCACA 1 -- int18Minor allele frequency- G:0.14NS EA NA WA CSA 540
    rs1815190631,2
    --36624326(+) TGTGGG/TTATGC 1 -- int10--------

    HapMap Linkage Disequilibrium report for MAP7D1 (36621180 - 36646450 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for MAP7D1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2746819CNV Deletion23290073
    esv2671242CNV Deletion23128226
    esv2671893CNV Deletion23128226
    nsv870558CNV Loss21882294
    nsv834691CNV Loss17160897
    nsv871426CNV Loss21882294
    nsv871804CNV Loss21882294
    nsv871396CNV Gain21882294
    dgv47e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MAP7D1 gene, integrated from 10 sources (see all 31):
    (articles sorted by number of sources associating them with MAP7D1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)1, 2, 3 Hirosawa M.... Ohara O. (DNA Res. 1999)
    2. Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry. (PubMed id 17370265)1, 2 Denis N.J.... Figeys D. (Proteomics 2007)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    5. The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition. (PubMed id 24163370)1 Lu L....Zhang L. (J. Biol. Chem. 2013)
    6. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    7. Interaction proteomics identify NEURL4 and the HECT E3 ligase HERC2 as novel modulators of centrosome architecture. (PubMed id 22261722)1 Al-Hakim A.K.... Pelletier L. (Mol. Cell. Proteomics 2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55700 HGNC: 25514 AceView: FLJ10350 Ensembl:ENSG00000116871 euGenes: HUgn55700
    ECgene: MAP7D1 H-InvDB: MAP7D1

    (According to HUGE)
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    HUGE: KIAA1187

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MAP7D1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MAP7D1 gene:
    Search GeneIP for patents involving MAP7D1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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