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MAP6 Gene

protein-coding   GIFtS: 52
GCID: GC11M075297

Microtubule-Associated Protein 6

  See MAP6-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Microtubule-Associated Protein 61 2     MTAP62
Stable Tubule-Only Polypeptide2 3     N-STOP2
MAP-62 3     KIAA18783
STOP2 3     

External Ids:    HGNC: 68681   Entrez Gene: 41352   Ensembl: ENSG000001715337   OMIM: 6017835   UniProtKB: Q96JE93   

Export aliases for MAP6 gene to outside databases

Previous GC identifers: GC06U990078 GC11U900013 GC11M075536 GC11M075040 GC11M075024 GC11M074975 GC11M071595


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MAP6 Gene:
This gene encodes a microtubule-associated protein. The encoded protein is a calmodulin-binding and
calmodulin-regulated protein that is involved in microtubule stabilization. Two transcript variants encoding
distinct isoforms have been identified for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for MAP6 Gene:
MAP6 (microtubule-associated protein 6) is a protein-coding gene. Diseases associated with MAP6 include ebstein anomaly. GO annotations related to this gene include microtubule binding and calmodulin binding. An important paralog of this gene is MAP6D1.

UniProtKB/Swiss-Prot: MAP6_HUMAN, Q96JE9
Function: Involved in microtubule stabilization in many cell types, including neuronal cells. Specifically has
microtubule cold stabilizing activity

Gene Wiki entry for MAP6 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_167190.2  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MAP6 gene promoter:
         PPAR-gamma1   Elk-1   POU2F1   POU2F1a   c-Myb   PPAR-gamma2   Zic3   c-Ets-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMAP6 promoter sequence
   Search Chromatin IP Primers for MAP6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MAP6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.5   Ensembl cytogenetic band:  11q13.5   HGNC cytogenetic band: 11q13.5

MAP6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAP6 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M075297:  view genomic region     (about GC identifiers)

Start:
75,297,963 bp from pter      End:
75,380,165 bp from pter
Size:
82,203 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MAP6_HUMAN, Q96JE9 (See protein sequence)
Recommended Name: Microtubule-associated protein 6  
Size: 813 amino acids; 86505 Da
Subunit: Interacts with calmodulin (via C-terminus); the interaction is dependent on Ca(2+) (By similarity)
Sequence caution: Sequence=AAH63860.1; Type=Erroneous initiation;
Secondary accessions: A7E2A1 Q6P3T0
Alternative splicing: 2 isoforms:  Q96JE9-1   Q96JE9-2   

Explore the universe of human proteins at neXtProt for MAP6: NX_Q96JE9

Explore proteomics data for MAP6 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See MAP6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_149052.1  NP_997460.1  

    ENSEMBL proteins: 
     ENSP00000307093   ENSP00000434278   ENSP00000415108  

    MAP6 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for MAP6

     
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    Search eBioscience for ELISAs for MAP6 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR024963 MAP6/FAM154
     IPR007882 MAP6

    Graphical View of Domain Structure for InterPro Entry Q96JE9

    ProtoNet protein and cluster: Q96JE9

    UniProtKB/Swiss-Prot: MAP6_HUMAN, Q96JE9
    Similarity: Belongs to the STOP family


    Find genes that share domains with MAP6           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MAP6_HUMAN, Q96JE9
    Function: Involved in microtubule stabilization in many cell types, including neuronal cells. Specifically has
    microtubule cold stabilizing activity

         Genatlas biochemistry entry for MAP6:
    microtubule associated protein 6 acting on the stability and dynamics of microtubules

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0005516calmodulin binding IEA--
    GO:0008017microtubule binding IEA--
         
    Find genes that share ontologies with MAP6           About GenesLikeMe


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Map6):
     behavior/neurological  mortality/aging  nervous system 

    Find genes that share phenotypes with MAP6           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MAP6
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MAP6

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MAP6
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    Block miRNA regulation of human, mouse, rat MAP6 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MAP6 (see all 17):
    hsa-miR-30c hsa-miR-29c hsa-miR-29a hsa-miR-30d hsa-miR-30a hsa-miR-376a* hsa-miR-155* hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmidMAP6 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat MAP6

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MAP6_HUMAN, Q96JE9: Cytoplasm, cytoskeleton. Golgi apparatus (By similarity). Note=Colocalizes with
    neurofilament (NF)-rich inclusions in spinal chord and brain neurons of patients with amyotrophic lateral
    sclerosis (ALS)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    golgi apparatus2
    mitochondrion2
    nucleus2
    cytosol1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus IEA--
    GO:0005874microtubule IDA17210638
    GO:0048471perinuclear region of cytoplasm IDA17210638

    Find genes that share ontologies with MAP6           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MAP6
    Interactions:

        Search GeneGlobe Interaction Network for MAP6

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    Selected Interacting proteins for MAP6 (Q96JE93 ENSP000003070934) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TUBB2AQ138853, ENSP000003697034I2D: score=1 STRING: ENSP00000369703
    TRAF1Q130773, ENSP000003629944I2D: score=1 STRING: ENSP00000362994
    RARGP136313I2D: score=3 
    RORBQ927533I2D: score=3 
    NR2F1P105893I2D: score=2 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000226microtubule cytoskeleton organization IEA--
    GO:0032418lysosome localization IMP--
    GO:0048813dendrite morphogenesis IMP--

    Find genes that share ontologies with MAP6           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MAP6



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MAP6 gene (2 alternative transcripts): 
    NM_033063.1  NM_207577.1  

    Unigene Cluster for MAP6:

    Microtubule-associated protein 6
    Hs.585540  [show with all ESTs]
    Unigene Representative Sequence: BC150254
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000304771(uc001owu.3) ENST00000526740 ENST00000526689 ENST00000434603(uc001owv.3)

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate MAP6 (see all 17):
    hsa-miR-30c hsa-miR-29c hsa-miR-29a hsa-miR-30d hsa-miR-30a hsa-miR-376a* hsa-miR-155* hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmidMAP6 3' UTR sequence
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAP6
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      QuantiTect SYBR Green Assays in human, mouse, rat MAP6
      QuantiFast Probe-based Assays in human, mouse, rat MAP6

    Additional mRNA sequence: 

    AB058781.1 AK054873.1 AK096511.1 AK123340.1 BC041411.1 BC063860.1 BC139780.1 BC150254.1 

    7 DOTS entries:

    DT.310930  DT.452419  DT.97793179  DT.40121218  DT.100670491  DT.100748695  DT.101976569 

    Selected AceView cDNA sequences (see all 123):

    AI077806 AI350327 BC063860 BE327485 AK123340 AI146518 BF439090 AI929437 
    AI368576 BU727491 AI090935 AL134649 BM722298 BG059683 BX952082 AL134650 
    BQ639076 AK096511 AW118357 AB058781 NM_207577 AW118394 CD105196 AW006157 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MAP6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACAGTAGTC
    MAP6 Expression
    About this image


    MAP6 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Neural Ectoderm (Nervous System)
             Neural ectoderm cells
     
     Neural Tube (Nervous System)
             Floor plate-like cells
    MAP6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MAP6 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.585540

    UniProtKB/Swiss-Prot: MAP6_HUMAN, Q96JE9
    Tissue specificity: Expressed in brain (at protein level). Expressed in spinal chord. Isoform 2 expression is
    up-regulated in the prefrontal cortex (Brodmann's area 46) of patients with schizophrenia (postmortem brain
    study)

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for MAP6 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Map61 , 5 microtubule-associated protein 61, 5 78.39(n)1
    73.19(a)1
      7 (54.05 cM)5
    177601  NM_010837.31  NP_034967.21 
     992674475 
    chicken
    (Gallus gallus)
    Aves MAP61 microtubule-associated protein 6 70.21(n)
    66.76(a)
      395753  NM_204919.1  NP_990250.1 
    lizard
    (Anolis carolinensis)
    Reptilia MAP66
    microtubule-associated protein 6
    53(a)
    1 ↔ 1
    GL343298.1(1120707-1179172)
    zebrafish
    (Danio rerio)
    Actinopterygii map6a1 microtubule-associated protein 6a 64(n)
    58.65(a)
      100000844  XM_001336510.5  XP_001336546.4 


    ENSEMBL Gene Tree for MAP6 (if available)
    TreeFam Gene Tree for MAP6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MAP6 gene
    MAP6D12  

    Find genes that share paralogs with MAP6           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MAP6 (see all 1446)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs5975011,2
    C,F,A,H--75297474(-) ATATAC/ACTAGa 1 -- ds50019Minor allele frequency- A:0.41NA WA CSA EA 373
    rs6507661,2
    C,F,H--75297481(-) CTAAAA/GAATAT 1 -- ds500111Minor allele frequency- G:0.28NA WA CSA EA 377
    rs1158740741,2
    C,F--75297785(+) ACCTCC/TGTGAT 1 -- ds50011Minor allele frequency- T:0.02WA 118
    rs5890631,2
    C,F,H--75297804(+) GTTTCA/CATCTA 1 -- ds500127Minor allele frequency- C:0.30NA NS EA WA CSA 2491
    rs1438040461,2
    --75297856(+) GAACTG/TGTGCT 1 -- ds50010--------
    rs5889551,2
    C,F,H--75297884(+) CCAGAT/CGGGTG 1 -- ds500134Minor allele frequency- C:0.25EA NA NS WA CSA 4585
    rs1472490121,2
    C--75297947(+) AGAGAC/TAGAGA 1 -- ds50010--------
    rs1487258121,2
    --75297996(+) TCCAGA/CAAGAC 1 -- ut310--------
    rs10554311,2
    C--75298022(-) TTAATC/TTGCAT 1 -- ut312Minor allele frequency- T:0.00NA 4
    rs1423202661,2
    --75298041(+) CTTCAC/TTGCCC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for MAP6 (75297963 - 75380165 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for MAP6:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2675287CNV Deletion23128226
    esv2744784CNV Deletion23290073
    nsv897923CNV Loss21882294

    Human Gene Mutation Database (HGMD): MAP6
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MAP6
    DNA2.0 Custom Variant and Variant Library Synthesis for MAP6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 601783    OMIM disorders: --

    1 disease for MAP6:    
    About MalaCards
    ebstein anomaly

    2 diseases from the University of Copenhagen DISEASES database for MAP6:
    Schizophrenia     Ebstein anomaly

    Find genes that share disorders with MAP6           About GenesLikeMe

    Genetic Association Database (GAD): MAP6
    Human Genome Epidemiology (HuGE) Navigator: MAP6 (2 documents)

    Export disorders for MAP6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MAP6 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with MAP6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic and expression analyses of the STOP (MAP6) gene in schizophrenia. (PubMed id 16624526)1, 2, 4, 9 Shimizu H.... Yoshikawa T. (Schizophr. Res. 2006)
    2. Assignment of the STOP gene (MAP6) to human chromosome bands 6p12--&gt;p11 by fluorescence in situ hybridization. (PubMed id 10516426)1, 3, 9 Jolly C....Job D. (Cytogenet. Cell Genet. 1999)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Stable tubule only polypeptides (STOP) proteins co-aggregate with spheroid neurofilaments in amyotrophic lateral sclerosis. (PubMed id 14692697)1, 2 Letournel F.... Eyer J. (J. Neuropathol. Exp. Neurol. 2003)
    5. The suppression of brain cold-stable microtubules in mice induces synaptic defects associated with neuroleptic-sensitive behavioral disorders. (PubMed id 12231625)1, 3 Andrieux A....Job D. (amp 2002)
    6. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2 Nagase T.... Ohara O. (DNA Res. 2001)
    7. Cloning, expression, and properties of the microtubule-stabilizing protein STOP. (PubMed id 8700896)1, 9 Bosc C....Margolis R.L. (Proc. Natl. Acad. Sci. U.S.A. 1996)
    8. Structural basis for the association of MAP6 protein with microtubules and its regulation by calmodulin. (PubMed id 23831686)1 LefA"vre J....Curmi P.A. (J. Biol. Chem. 2013)
    9. MAP6-F is a temperature sensor that directly binds to and protects microtubules from cold-induced depolymerization. (PubMed id 22904321)1 Delphin C....Andrieux A. (J. Biol. Chem. 2012)
    10. Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. (PubMed id 19165527)1 Martins-de-Souza D....Turck C.W. (Eur Arch Psychiatry Clin Neurosci 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 4135 HGNC: 6868 AceView: MAP6 Ensembl:ENSG00000171533 euGenes: HUgn4135
    ECgene: MAP6 H-InvDB: MAP6

    (According to HUGE)
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    HUGE: KIAA1878

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for MAP6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MAP6 gene:
    Search GeneIP for patents involving MAP6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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