MAP4K3 Gene
protein-coding GIFtS: 60
GCID: GC02M039476
|
|
mitogen-activated protein kinase kinase kinase kinase 3
(Previous symbol: RAB8IPL1)
| |
Aliases
for MAP4K3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Mitogen-Activated Protein Kinase Kinase Kinase Kinase 31 2 | | MEK Kinase Kinase 32 3 | | GLK1 2 3 | | MEKKK 32 3 | | RAB8IPL11 2 3 | | EC 2.7.11.13 8 | | MAPKKKK31 2 | | MEKKK32 | | Germinal Center Kinase-Related Protein Kinase2 3 | | Germinal Center Kinase-Like Kinase2 | | MAPK/ERK Kinase Kinase Kinase 32 3 | | EC 2.7.118 |
Export aliases for MAP4K3 gene to outside databasesPrevious GC identifers: GC02M039440 GC02M039623 GC02M039450 GC02M039388 GC02M039329 GC02M039215 |
Summaries
for MAP4K3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MAP4K3:
This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded proteinactivates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multipleisoforms have been observed for this gene. (provided by RefSeq, Jul 2012)
UniProtKB/Swiss-Prot: M4K3_HUMAN, Q8IVH8Function: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminalpathway
|
Genomic Views
for MAP4K3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MAP4K3 gene promoter:
SRF AML1a SRF (504 AA) HTF CUTL1 RORalpha1 PPAR-alpha HSF2 Msx-1 NF-AT1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MAP4K3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAP4K3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p22.1 Ensembl cytogenetic band: 2p22.1 HGNC cytogenetic band: 2p22.3MAP4K3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M039476: view genomic region
(about GC identifiers)
Start:
|
39,476,407 bp from pter |
End:
|
39,664,453 bp from pter |
Size:
|
188,047 bases |
Orientation:
|
minus strand |
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Proteins
for MAP4K3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: M4K3_HUMAN, Q8IVH8 (See
protein sequence)Recommended Name: Mitogen-activated protein kinase kinase kinase kinase 3 Size: 894 amino acids; 101316 Da
Cofactor: Magnesium
Subunit: Interacts with SH3GL2. Interaction appears to regulate MAP4K3-mediated JNK activation (By similarity)
Secondary accessions: Q6IQ39 Q8IVH7 Q9UDM5 Q9Y6R5Alternative splicing: 3 isoforms: Q8IVH8-1 Q8IVH8-2 Q8IVH8-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MAP4K3: NX_Q8IVH8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IVH8
4/25 DME Specific Peptides for MAP4K3 (Q8IVH8) (see all 25)
MAP4K3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001257354.1 NP_003609.2
ENSEMBL proteins: ENSP00000263881 ENSP00000416958 ENSP00000345434 ENSP00000399228 ENSP00000405137 ENSP00000410183 ENSP00000440580
Human Recombinant Protein Products:
MAP4K3 Antibody Products:
Assay Products for MAP4K3: |
Protein
Domains /
Families
for MAP4K3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MAP4K3 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q8IVH8ProtoNet protein and cluster: Q8IVH8 1 Blocks protein family: IPB001180 Citron-like
UniProtKB/Swiss-Prot: M4K3_HUMAN, Q8IVH8Similarity: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamilySimilarity: Contains 1 CNH domainSimilarity: Contains 1 protein kinase domain |
Function
for MAP4K3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: M4K3_HUMAN, Q8IVH8Function: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminalpathwayCatalytic activity: ATP + a protein = ADP + a phosphoproteinEnzyme Numbers (IUBMB): EC 2.7.11.11 2 EC 2.7.112
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAP4K3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAP4K3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MAP4K3 (NM_003618) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MAP4K3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAP4K3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAP4K3 |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
MAP4K3 for ontologies About GeneDecksing
5 GenomeRNAi human phenotypes for MAP4K3:
Animal Models:
3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Map4k3):
MAP4K3 for phenotypes About GeneDecksing
|
Pathways & Interactions
for MAP4K3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signal transduction_JNK pathway | | | 2 | MAPK signaling pathway | | | 3 | TGF-Beta Pathway | | | 4 | Insulin Signaling | | | 5 | TNF receptor signaling pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for MAP4K3
2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for MAP4K3
1 
Cell Signaling Technology (CST) Pathway for MAP4K3
1  GeneGo (Thomson Reuters) Pathway for MAP4K3
3  BioSystems Pathways for MAP4K3
1 
Kegg Pathway (Kegg details for MAP4K3):
MAP4K3 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MAP4K3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 15)
5/27 Interacting proteins for MAP4K3 (Q8IVH81, 3 ENSP000002638814) via UniProtKB, MINT, STRING, and/or I2D (see all 27)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
MAP4K3 for ontologies About GeneDecksing
|
Drugs & Compounds
for MAP4K3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MAP4K3 for compounds About GeneDecksing
 Browse Tocris compounds for MAP4K3
3 HMDB Compounds for MAP4K3 About this table
2 Novoseek chemical compound relationships for MAP4K3 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| threonine |
50.6 |
2 |
9820741 (1), 10979967 (1) |
| serine |
37.7 |
2 |
9820741 (1), 10979967 (1) |
Search CenterWatch for drugs/clinical trials and news about MAP4K3 / M4K3
|
Transcripts
for MAP4K3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MAP4K3 gene (2 alternative transcripts): NM_001270425.1 NM_003618.3 Unigene Cluster for MAP4K3: Mitogen-activated protein kinase kinase kinase kinase 3 Hs.655750 [show with all ESTs]Unigene Representative Sequence: NM_00361814 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000263881(uc010yns.2 uc002rro.3 uc002rrp.3) ENST00000437545
ENST00000341681 ENST00000479708 ENST00000475457 ENST00000495648 ENST00000497566
ENST00000474502 ENST00000465701 ENST00000414968 ENST00000429397 ENST00000437968
ENST00000484274 ENST00000536018
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAP4K3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAP4K3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MAP4K3 (NM_003618) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MAP4K3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAP4K3 |
Additional cDNA sequence: AK021553.1 AK291467.1 AK299889.1 AK314487.1 AK316144.1 BC060880.1 BC071579.1 18 DOTS entries: DT.92002754 DT.70104021 DT.100650188 DT.120962589 DT.120962500 DT.40108322 DT.95155821 DT.100755411 DT.116209 DT.120962675 DT.207519 DT.75112927 DT.75129923 DT.91935214 DT.92427062 DT.92427066 DT.95290103 DT.120962704 24/110 AceView cDNA sequences (see all 110): BX955753 AK021553 AI918730 AU117665 NM_003618 CA446177 AA741136 BM786598 BM828868 AA844713 BX506982 AA258988 AA250885 AA250828 N50618 AA605308 BC060880 AI803730 BU852924 AA453226 BG708225 AW006909 AI741612 AV708133
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for MAP4K3 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 26a | · | 26b | ^ | 27a | · | 27b | ^ | 28 | ^ | 29a | · | 29b | · | 29c | ^ | 30 | ^ | 31 | ^ | 32 | ^ | 33 | ^ | 34 |
|---|
|
| SP1: | | | - | | - | | | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | - | | - | | | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MAP4K3
|
Expression
for MAP4K3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MAP4K3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTTTTAACA
About this image
See MAP4K3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MAP4K3
SOURCE GeneReport for Unigene cluster: Hs.655750
UniProtKB/Swiss-Prot: M4K3_HUMAN, Q8IVH8Tissue specificity: Ubiquitously expressed in all tissues examined, with high levels in heart, brain, placenta,skeletal muscle, kidney and pancreas and lower levels in lung and liver
SABiosciences Custom PCR Arrays for MAP4K3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAP4K3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat MAP4K3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAP4K3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAP4K3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAP4K3 |
Orthologs
for MAP4K3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for MAP4K3 gene from 5/22 species (see all 22) About this table
ENSEMBL Gene Tree for MAP4K3 (if available)
TreeFam Gene Tree for MAP4K3 (if available) |
Paralogs
for MAP4K3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MAP4K3 gene
- TAOK22 MAP4K52 TAOK32 NRK2 TNIK2 MAP4K22 MAP4K12 MAP4K42
- TAOK12 STK102 MINK12 SLK2
18/50 SIMAP similar genes for MAP4K3 using alignment to 7 protein entries: M4K3_HUMAN (see all proteins)
(see all similar genes):MAP4K5 CDK2 MAP4K2 PNCK TNIK MYO3A
MAP4K1 MAP4K4 STK25 CDK1 STK24 PAK2
PAK4 STK3 PAK1 DKFZp686J1430 STK4 MST4
MAP4K3 for paralogs About GeneDecksing
|
Genomic Variants
for MAP4K3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MAP4K3 (39476407 - 39664453 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for MAP4K3
2 CNVs: 97823 97822
1 Indel: 60295 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for MAP4K3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MAP4K3 for disorders About GeneDecksing
OMIM gene information: 604921
OMIM disorders: --
1  disease for MAP4K3: About MalaCardslung cancer
Human Genome Epidemiology (HuGE) Navigator: MAP4K3 (6 documents)
Export disorders for MAP4K3 gene to outside databases
|
Publications
for MAP4K3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MAP4K3 gene, integrated from 9 sources (see all 26):
(articles sorted by number of sources associating them with MAP4K3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase. (PubMed id 9275185)1, 2, 3, 9 Diener K.... Yao Z. (1997)
- The kinase GLK controls autoimmunity and NF-I_B signal ing by activating the kinase PKC-I, in T cells. (PubMed id 21983831)1 Chuang H.C....Tan T.H. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrien t signaling to mTOR. (PubMed id 20227368)1 Yan L....Lamb R.F. (2010)
- A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (2010)
- Replication of previous genome-wide association studi es of bone mineral density in premenopausal American women. (PubMed id 20200978)1 Ichikawa S....Econs M.J. (2010)
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
- MAP4K3 modulates cell death via the post-transcriptio nal regulation of BH3-only proteins. (PubMed id 19587239)1 Lam D....Martins L.M. (2009)
- Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
- Large-scale proteomics analysis of the human kinome. (PubMed id 19369195)2 Oppermann F.S.... Daub H. (2009)
|
External Searches for MAP4K3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MAP4K3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MAP4K3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MAP4K3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for MAP4K3 gene:
Search GeneIP for patents involving MAP4K3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MAP4K3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MAP4K3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MAP4K3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAP4K3 | | | OriGene Protein Over-expression Lysate for MAP4K3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MAP4K3 | | OriGene 3'-UTR Clone for MAP4K3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAP4K3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAP4K3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MAP4K3 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MAP4K3 | | OriGene Custom Protein Services for MAP4K3 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MAP4K3 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAP4K3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAP4K3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAP4K3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAP4K3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAP4K3 |
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| | Antibodies & Assays for MAP4K3 (KHS2) |
| | | | Search Tocris compounds for MAP4K3 |
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 | | | MAP4K3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAP4K3 |
|  |  |  | | | | ThermoFisher Antibody for MAP4K3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAP4K3 |
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