Aliases for MAP4K1 Gene
External Ids for MAP4K1 Gene
Previous GeneCards Identifiers for MAP4K1 Gene
GeneCards Summary for MAP4K1 Gene
MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1) is a Protein Coding gene. Among its related pathways are TCR signaling in naive CD4+ T cells and TGF-Beta Pathway. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is MAP4K3.
UniProtKB/Swiss-Prot for MAP4K1 Gene
Serine/threonine-protein kinase, which may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation. Able to autophosphorylate.